Dr. rer. nat. habil. Beate Fuchs

+49 38208 68-852
Leibniz-Institut für Nutztierbiologie (FBN)
Servicegruppe Metabolom
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Regulation des Lipidstoffwechsels
  • Lipidomics, Metabolomics
  • Massenspektrometrie & Analytik (GC-MS/MS, MALDI-TOF-MS, TLC, HR-ESI-MS/MS)

Lebenslauf

  • 2017-heute Leiterin der Zentralen Servicegruppe - Metabolomics, Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2016 Habilitation (Dr. rer. nat. habil.) an der Medizinischen Fakultät Leipzig
  • 2016 Forschungsaufenthalt an der University of Pittsburgh, USA
  • 2009-2017 Arbeitsgruppenleiterin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2007-2009 Wissenschaftlerin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2006 Forschungsaufenthalt an der Strathclyde University in Glasgow, UK
  • 2004 Forschungsaufenthalt an der University of Louisville, Kentucky, USA
  • 2002-2006 Postgradualstudium Toxikologie, University Leipzig, Abschluss: Fachchemikerin für Toxikologie und Umweltschutz
  • 2002-2006 Postdoc am Interdisziplinären Zentrum für Klinische Forschung (IZKF) der Medizinischen Fakultät Leipzig ("NMR und MALDI-TOF-MS-Untersuchungen des Knorpelabbaus bei Rheumatischer Arthritis: Strukturaufklärung und klinisches Monitoring")
  • 1998-2001 Doktorandin am Leibniz-Institut für Polymerforschung Dresden (Thema: 19F-NMR-Untersuchungen an strahlenmodifizierten Fluorpolymeren)
  • 1996-1997 Stipendiatin der Carl-Duisberg-Gesellschaft und Praktikantin bei Bayer de México in Mexico-City
  • 1996 Diplomarbeit in der "Analytischen Chemie" an der TU Freiberg (Thema: 31C-NMR-Untersuchungen von strukturellen Änderungen mikrobiell behandelter Braunkohle)

Publikationen

Ditz, T.; Schnapka-Hille, L.; Noack, N.; Dorow, J.; Ceglarek, U.; Niederwieser, D.; Schiller, J.; Fuchs, B.; Cross, M. (2019):
Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation 105: 27-32
Ditz, T.; Fuchs, B. (2018):
Determination of the phosphatidylcholine/lysophosphatidylcholine ratio in intact serum by matrix-assisted laser desorption/ionisation mass spectrometry with prior enzymatic albumin digestion. Lipids 53: 971-977
Broniec, A.; Zadlo, A.; Pawlak, A.; Fuchs, B.; Klosinski, R.; Thompson, D.; Sarna, T. (2017):
Interaction of plasmenylcholine with free radicals in selected model systems. Free Radic Biol Med 106: 368-378
Dinkla, S.; van Eijk, L. T.; Fuchs, B.; Schiller, J.; Joosten, I.; Brock, R.; Pickkers, P.; Bosman, G. J. (2016):
Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane. BBA Clin 5: 186-192
Schroter, J.; Griesinger, H.; Reuss, E.; Schulz, M.; Riemer, T.; Suss, R.; Schiller, J.; Fuchs, B. (2016):
Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry. J Chromatogr A 1439: 89-96
Fuchs, B. (2015):
Analytical methods for (oxidized) plasmalogens: Methodological aspects and applications. Free Radical Res 49: 599-617
Fuchs, B.; Popkova, Y.; Suss, R.; Schiller, J. (2015):
Separation of (Phospho)Lipids by Thin-Layer Chromatography. Instrumental Thin-Layer Chromatography 375-405
Angelini, R.; Vortmeier, G.; Corcelli, A.; Fuchs, B. (2014):
A fast method for the determination of the PC/LPC ratio in intact serum by MALDI-TOF MS: An easy-to-follow lipid biomarker of inflammation. Chem Phys Lipids 183: 169-175
Fuchs, B.; Schiller, J. (2014):
Glycosaminoglycan degradation by selected reactive oxygen species. Antioxid Redox Signal 21: 1044-1062
Palusinska-Szysz, M.; Kania, M.; Turska-Szewczuk, A.; Danikiewicz, W.; Russa, R.; Fuchs, B. (2014):
Identification of Unusual Phospholipid Fatty Acyl Compositions of Acanthamoeba castellanii. Plos One 9: e01243
Fuchs, B. (2014):
Mass spectrometry and inflammation--MS methods to study oxidation and enzyme-induced changes of phospholipids. Anal Bioanal Chem 406: 1291-1306
Griesinger, H.; Fuchs, B.; Suss, R.; Matheis, K.; Schulz, M.; Schiller, J. (2014):
Stationary phase thickness determines the quality of thin-layer chromatography/matrix-assisted laser desorption and ionization mass spectra of lipids. Anal Biochem 451: 45-47
Wegener, J.; Zschornig, K.; Onischke, K.; Fuchs, B.; Schiller, J.; Muller, K. (2013):
Conservation of honey bee (Apis mellifera) sperm phospholipids during storage in the bee queen - A TLC/MALDI-TOF MS study. Exp Gerontol 48: 213-222
Eibisch, M.; Riemer, T.; Fuchs, B.; Schiller, J. (2013):
Differently saturated fatty acids can be differentiated by 31P NMR subsequent to derivatization with 2-chloro-4,4,5,5-tetramethyldioxaphospholane: a cautionary note. J Agric Food Chem 61: 2696-2700
Nimptsch, A.; Fuchs, B.; Suss, R.; Zschornig, K.; Jakop, U.; Goritz, F.; Schiller, J.; Muller, K. (2013):
A simple method to identify ether lipids in spermatozoa samples by MALDI-TOF mass spectrometry. Anal Bioanal Chem 405: 6675-6682
Fuchs, B. (2012):
Analysis of phospolipids and glycolipids by thin-layer chromatography-matrix-assisted laser desorption and ionization mass spectrometry. J Chromatogr A 1259: 62-73
Dinkla, S.; Wessels, K.; Verdurmen, W. P. R.; Tomelleri, C.; Cluitmans, J. C. A.; Fransen, J.; Fuchs, B.; Schiller, J.; Joosten, I.; Brock, R.; Bosman, G. J. C. G. M. (2012):
Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. Cell Death Dis 3: e410
Fuchs, B.; Muller, K.; Paasch, U.; Schiller, J. (2012):
Lysophospholipids: potential markers of diseases and infertility? Mini Rev Med Chem 12: 74-86
Jakop, U.; Fuchs, B.; Rudiger, K.; Schiller, J.; Muller, K.; Schulze, M. (2012):
Screening of boar sperm for their resistance to storage at low temperatures. Reprod Domest Anim 47: 7-7
Eibisch, M.; Fuchs, B.; Schiller, J.; Suss, R.; Teuber, K. (2011):
Analysis of Phospholipid Mixtures from Biological Tissues by Matrix-Assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS): A Laboratory Experiment. J Chem Educ 88: 503-507