PD Dr. rer. nat. habil. Jens Vanselow

+49 38208 68-752
Leibniz-Institut für Nutztierbiologie (FBN)
Institut für Fortpflanzungsbiologie
Institutsleitung
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Reproduktionsbiologie
  • Follikulogenese, Luteinisierung
  • Genregulation
  • Epigenetik

Lebenslauf

  • 2013-heute: Leiter des Instituts für Fortpflanzungsbiologie am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2002: Habilitation und Dozent an der Mathematisch-Naturwissenschaftlichen Fakultät und Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 1992-2012: Leiter der Abteilung Genregulation am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf, Forschungsbereich Molekularbiologie
  • 1990-1992: Postdoc-Stipendiat des Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow am Massachusetts General Hospital, Institut für Entwicklungsbiologie, Boston, USA
  • 1988-1990: Mitglied des DFG Graduierten Kollegs "Neurobiologie" an der Eberhard Karls Universität Tübingen
  • 1990: Promotion zum Dr. rer. nat. an der Eberhard Karls Universität Tübingen und am Max-Planck-Institut für Entwicklungsbiologie Tübingen
  • 1987: Diplom in Biologie an der Eberhard Karls Universität Tübingen
  • 1983: Vordiplom in Biologie an der Johannes Gutenberg University Mainz

Lehre

  • 2013-heute: "Populationsgenetik, molekulare Tierzucht und Reproduktionstechniken" (MSc) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2014-heute: "Zuchtprogramme und Reproduktionsmanagement" (B.Sc.) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2011-heute: "Molekulare Tierzucht" (MSc) an der Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock
  • 1997-2010: "Molekulare Mechanismen der Entwicklung und and Differenzierung" (Dipl.-Biol.), Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock

Publikationen

Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
Sharma, A.; Baddela, V. S.; Becker, F.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect (https://doi.org/10.1530/EC-19-0011)
Baddela, V. S.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
Global gene expression analysis indicates that small luteal cells are involved in extracellular matrix modulation and immune cell recruitment in the bovine corpus luteum. Mol Cell Endocrinol 474: 201-213
Baufeld, A.; Vanselow, J. (2018):
Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage. Reprod Biol Endocrin 16: 15, 1-11
Baddela, V. S.; Sharma, A.; Viergutz, T.; Koczan, D.; Vanselow, J. (2018):
Low oxygen levels induce early luteinization associated changes in bovine granulosa cells. Front Physiol 9: 1066, 1-15
Baddela, V. S.; Sharma, A.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
mRNA microarraydata of FACS purified bovine small and large luteal cells. Data in brief 19: 737-742
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. J Vis Exp 139: e58208
Baufeld, A.; Koczan, D.; Vanselow, J. (2017):
Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density. Reprod Biol Endocrin 15: 3, 1-14
Yenuganti, V.; Vanselow, J. (2017):
Cultured bovine granulosa cells rapidly lose important features of their identity and functionality but partially recover under long-term culture conditions. Cell Tissue Res 368 (2): 397-403
Yenuganti, V.; Vanselow, J. (2017):
Oleic acid induces down-regulation of the granulosa cell identity marker FOXL2, and up-regulation of the Sertoli cell marker SOX9 in bovine granulosa cells. Reprod Biol Endocrin 15: 57, 1-5
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Metges, C. C. (2016):
Maternal high-protein diet during pregnancy, but not during suckling, induced altered expression of an increasing number of hepatic genes in adult mouse offspring. Eur J Nutr 55 (3): 917-930
Yenuganti, V.; Viergutz, T.; Vanselow, J. (2016):
Oleic acid induces specific alterations in the morphology, gene expression and steroid hormone production of cultured bovine granulosa cells. Gen Comp Endocr 232: 134-144
Vanselow, J.; Vernunft, A.; Koczan, D.; Spitschak, M.; Kuhla, B. (2016):
Exposure of lactating dairy cows to acute pre-ovulatory heat stress affects granulosa cell-specific gene expression profiles in dominant follicles. Plos One 11 (8): e0160600, 1-19
Shrestha, K.; Lukasik, K.; Baufeld, A.; Vanselow, J.; Moallem, U.; Meidan, R. (2015):
Regulation of ovulatory genes in bovine granulosa cells: lessons from siRNA silencing of PTGS2. Reproduction 149 (1): 21-29
Chang, G.; Petzl, W.; Vanselow, J.; Günther, J.; Shen, Z.; Seyfert, H.-M. (2015):
Epigenetic mechanisms contribute to enhanced expression of immune response genes in the liver of cows after experimentally induced Escherichia coli mastitis. Vet J 203 (3): 339-341
Yenuganti, V.; Baddela, V.S.; Baufeld, A.; Singh, D.; Vanselow, J. (2015):
The gene expression pattern induced by high plating density in cultured bovine and buffalo granulosa cells might be regulated by specific miRNA species. J Reprod Develop 61 (2): 154-160
Kunze, M.; Wirthgen, E.; Walz, C.; Spitschak, M.; Brenmoehl, J.; Vanselow, J.; Schwerin, M.; Wimmers, K.; Hoeflich, A. (2015):
Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC-MS/MS. J Chromatogr B 1007: 132-139
Rudolf, H.; Nuernberg, G.; Koczan, D.; Vanselow, J.; Gempe, T.; Beye, M.; Leboulle, G.; Bienefeld, K.; Reinsch, N. (2015):
On the relevance of technical variation due to building pools in microarray experiments. BMC Genomics 16: 1027, 1-12
Sahmi, F.; Nicola, E.S.; Zamberlam, G. O.; Goncalves, P. D. B.; Vanselow, J.; Price, C.A. (2014):
Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model. Gen Comp Endocr 200: 10-17
Vanselow, J. (2014):
Modified maternal protein supply imprints persistent alterations on offspring growth, hepatic gene expression and epigenetic profiles. In: Invited Lectures: Climate Resilient Livestock Feeding Systems for Global Food Security (Samanta,A.K., Bhatta,V., Sej