Dr. agr. Winfried Otten

+49 38208 68-802
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Verhaltensphysiologie
Abteilung Psychophysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

    • Glucocorticoide in Haaren und Federn als Bioindikator zum retrospektiven, minimal-invasiven Monitoring für Tierwohl in verschiedenen Nutztierspezies
    • Tryptophan Metabolismus: Relevanz für die Immunfunktion sowie Stimmug und Verhalten
    • Analyse von Neurotransmittern und Katecholaminen, ihren Vorläufern und Metaboliten in biologischen Proben mithilfe der High performance liquid chromatography (HPLC)

      Lebenslauf

      • 1992-heute: Wissenschaftler am Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf, Institut für Verhaltensphysiologie
      • 1993: Promotion an der Technischen Universität München
      • 1984-1989: Studium der Agrarwissenschaften mit Schwerpunkt Tierproduktion an der Technischen Universität München

      Lehre

      Universität Rostock, Agrarwissenschaften (Bachelor) Themen: Stress, Tierwohl

      Publikationen

      Tuchscherer, M.; Otten, W.; Kanitz, E.; Gräbner, M.; Tuchscherer, A.; Bellmann, O.; Rehfeldt, C.; Metges, C. C. (2012):
      Effects of inadequate maternal dietary protein:carbohydrate ratios during pregnancy on offspring immunity in pigs. BMC Vet Res 8: 232-243
      https://dx.doi.org/10.1186/1746-6148-8-232
      Gimsa, U.; Kanitz, E.; Otten, W.; Tuchscherer, M.; Tuchscherer, A.; Ibrahim, S. M. (2012):
      Tumour necrosis factor receptor deficiency alters anxiety-like behavioural and neuroendocrine stress responses of mice. Cytokine 59 (1): 72-78
      https://dx.doi.org/10.1016/j.cyto.2012.04.001
      Metzler-Zebeli, B. U.; Lang, I. S.; Görs, S.; Brüssow, K.-P.; Hennig, U.; Nürnberg, G.; Rehfeldt, C.; Otten, W.; Metges, C. C. (2012):
      High-protein-low-carbohydrate diet during pregnancy alters maternal plasma amino acid concentration and placental amino acid extraction but not fetal plasma amino acids in pigs. Brit J Nutr 108 (12): 2176-2189
      https://dx.doi.org/10.1017/S0007114512000414
      Metges, C. C.; Lang, I. S.; Hennig, U.; Brüssow, K.-P.; Kanitz, E.; Tuchscherer, M.; Schneider, F.; Weitzel, J. M.; Steinhoff-Ooster, A.; Sauerwein, H.; Bellmann, O.; Nürnberg, G.; Rehfeldt, C.; Otten, W. (2012):
      Intrauterine growth retarded progeny of pregnant sows fed high protein:low carbohydrate diet is related to metabolic energy deficit. Plos One 7 (2): 1-10
      https://dx.doi.org/10.1371/journal.pone.0031390
      Rehfeldt, C.; Stabenow, B.; Pfuhl, R.; Block, J.; Nürnberg, G.; Otten, W.; Metges, C. C.; Kalbe, C. (2012):
      Effects of limited and excess protein intake of pregnant gilts on carcass quality and cellular properties of skeletal muscle and subcutaneous adipose tissue in fattening pigs. J Anim Sci 90 (1): 184-196
      https://dx.doi.org/10.2527/jas.2011-4234
      Rehfeldt, C.; Lefaucheur, L.; Block, J.; Stabenow, B.; Pfuhl, R.; Otten, W.; Metges, C. C.; Kalbe, C. (2012):
      Limited and excess protein intake of pregnant gilts differently affects body composition and cellularity of skeletal muscle and subcutaneous adipose tissue of newborn and weanling piglets. Eur J Nutr 51 (2): 151-165
      https://dx.doi.org/10.1007/s00394-011-0201-8
      Rehfeldt, C.; Lang, I. S.; Görs, S.; Hennig, U.; Kalbe, C.; Stabenow, B.; Brüssow, K.-P.; Pfuhl, R.; Bellmann, O.; Nürnberg, G.; Otten, W.; Metges, C. C. (2011):
      Limited and excess dietary protein during gestation affects growth and compositional traits in gilts and impairs offspring fetal growth. J Anim Sci 89 (2): 329-341
      https://dx.doi.org/10.2527/jas.2010-2970
      Le Floch, N.; Otten, W.; Merlot, E. (2011):
      Tryptophan metabolism, from nutrition to potential therapeutic applications. Amino Acids 41 (5): 1195-1205
      https://dx.doi.org/10.1007/s00726-010-0752-7
      Zimmermann, S; Zöls, S.; Otten, W.; Palzer, A.; Ritzmann, M.; Heinritzi, K. (2011):
      Evaluation of carbon dioxide anaesthesia for the castration of male suckling piglets by stress hormone concentrations, behaviour and clinical factors. Berl Munch Tierarztl 124 (9/10): 368-375
      https://dx.doi.org/10.2376/0005-9366-124-368
      Gimsa, U.; Kanitz, E.; Otten, W.; Aheng, C.; Tuchscherer, M.; Ricquier, D.; Miroux, B.; Ibrahim, S. M. (2011):
      Alterations in anxiety-like behavior following knockout of the uncoupling protein 2 (ucp2) gene in mice. Life Sci 89 (19-20): 677-684
      https://dx.doi.org/10.1016/j.lfs.2011.08.009
      Kanitz, E.; Otten, W.; Hameister, T.; Tuchscherer, M.; Puppe, B.; Tuchscherer, A. (2011):
      Age-related changes in corticosteroid receptor expression and monoamine neurotransmitter concentrations in various brain regions of postnatal pigs. J Neurosci Res 89 (7): 1134-1141
      https://dx.doi.org/10.1002/jnr.22621
      Rehfeldt, C.; Block, J.; Lefaucheur, L.; Stabenow, B.; Otten, W.; Metges, C. C.; Kalbe, C. (2010):
      Inadequate protein intake of pregnant gilts affects body composition and skeletal muscle properties of newborn piglets. In: Energy and protein metabolism and nutrition, EAAP publication No. 127, 2010, 3rd EAAP ISEP, Parma, Italy, 6-10 September 2010 (ed. G. Matteo Corvetto, Hrsg.) Wageningen Academic Publishers, The Netherlands, (ISSN 0071-2477): 383-384
      Kiank, C.; Zeden, J.P.; Drude, S.; Domanska, G.; Fusch, G.; Otten, W.; Schütt, C. (2010):
      Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans. Plos One 5 (7): 1-12
      https://dx.doi.org/10.1371/journal.pone.0011825
      Otten, W.; Kanitz, E.; Couret, D.; Veissier, I.; Prunier, Armelle; Merlot, E. (2010):
      Maternal social stress during late pregnancy affects hypothalamic-pituitary-adrenal function and brain neurotransmitter systems in pig offspring. DOMEST ANIM ENDOCRIN 38 (3): 146-156
      https://dx.doi.org/10.1016/j.domaniend.2009.09.002
      Mühlbauer, I.C.; Otten, W.; Lüpping, W.; Palzer, A.; Zöls, S.; Elicker, S.; Ritzmann, M.; Heinritzi, K. (2009):
      Untersuchung zur CO2-Narkose als eine Alternative zur betäubungslosen Kastration von Saugferkeln. Prakt Tierarzt 90 (5): 460-464
      Gimsa, U.; Kanitz, E.; Otten, W.; Ibrahim, S. M. (2009):
      Behavior and stress reactivity in mouse strains with mitochondrial DNA variations. Ann NY Acad Sci 1153: 131-138
      https://dx.doi.org/10.1111/j.1749-6632.2008.03960.x
      Gräbner, M.; Kanitz, E.; Otten, W. (2009):
      Pränataler Stress bei Nutztieren: Eine Übersicht. Berl Munch Tierarztl 122 (3/4): 73-81
      https://dx.doi.org/10.2376/0005-9366-122-73
      Yu, X.; Gimsa, U.; Wester-Rosenlöf, L.; Kanitz, E.; Otten, W.; Kunz, M.; Ibrahim, S. M. (2009):
      Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res 19 (1): 159-165
      https://dx.doi.org/10.1101/gr.078865.108
      Couret, D.; Otten, W.; Puppe, B.; Prunier, Armelle; Merlot, E. (2009):
      Behavioural, endocrine and immune responses to repeated social stress in pregnant gilts. Animal 3 (1): 118-127
      https://dx.doi.org/10.1017/S1751731108003236
      Puppe, B.; Meunier-Salaün, M.C.; Otten, W.; Orgeur, P. (2008):
      The welfare of piglets.. In: Welfare of Pigs (L. Faucitanio & A.L. Schaefer, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-066-1): 97-132