Prof. Dr. rer. nat. habil. Ulrike Gimsa
Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Psychophysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiterin der Arbeitsgruppe Psychophysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Stress-induzierte Immunmodulation in Nutz- und Modelltieren
- Immunologie
- Neurobiologie
Lebenslauf
- 2012: Professor für Immunologie an der Universität Rostock
- 2006–heute: Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf, Institut für Verhaltensphysiologie
- 2005: Venia legendi (PD) in Immunologie an der Universität Rostock
- 2004: Habilitation (facultas docendi) in Immunologie am Universitätsklinikum Charité, Berlin
- 1995: Promotion in Zellbiologie
- 1991: Diplom in Biophysik an der Humboldt Universität, Berlin
Lehre
- Vorlesung "Grundlagen und Anwendung immunologischer Nachweismethoden" am Institut für Biowissenschaften der Universität Rostock, Master Programm
- Vorlesung: "Immunglobuline" am Institut für Biowissenschaften der Universität Rostock, Bachelor Programm
Publikationen
Buehler, S. M.; Stubbe, M.; Gimsa, U.; Baumann, W.; Gimsa, J. (2011):
A decrease of intracellular ATP is compensated by increased respiration and acidification at sub-lethal parathion concentrations in murine embryonic neuronal cells: Measurements in metabolic cell-culture chips. Toxicol lett 207 (2): 182-190
https://dx.doi.org/10.1016/j.toxlet.2011.09.005
Nowak, K.; Mix, E.; Gimsa, J.; Strauss, U.; Sriperumbudur, K.; Benecke, R.; Gimsa, U. (2011):
Optimizing a rodent model of Parkinson's disease for exploring the effects and mechanisms of deep brain stimulation. Parkinsons Disease 2011: 1-19
https://dx.doi.org/10.4061/2011/414682
van Rienen, U.; Appali, R.; Bader, R.; Baumann, W.; Beck, U.; Behrend, D.; Benecke, R.; Biala, K.; Birkholz, H.; Burkel, E.; Engel, M.; Gimsa, J.; Gimsa, U.; Gongadze, E.; Grünbaum, A.; Haba, Y.; Liese, F.; Liu, B.; Lüder, M.; Matschegewski, C.; Mittelmeier, W.; Mix, E.; Nebe, B.; Nowak, K.A.; Pahnke, J.; Petersen, S.; Polnick, S.; Reimer, T.; Rott, G.; Salomon, R.; Vinter, E.; Weihe, T.; Wolkenhauer, O. (2010):
Analyse und Simulation von Wechselwirkungen von Implantaten und Biosystemen. Biomed Tech 55 (Suppl.1): 1-4
Yu, X.; Wester-Rosenlöf, L.; Gimsa, U.; Holzhueter, S.; Marques, A.; Jonas, L.; Bauer, K.; Kunz, M.; Nizze, H.; Tiedge, M.; Holmdahl, R.; Ibrahim, S. M. (2009):
The mtDNA nt7778 G/T polymorphism affects autoimmune diseases and reproductive performance in the mouse. Hum Mol Genet 18 (24): 4689-4698
https://dx.doi.org/10.1093/hmg/ddp432
Gimsa, U.; Kanitz, E.; Otten, W.; Ibrahim, S. M. (2009):
Behavior and stress reactivity in mouse strains with mitochondrial DNA variations. Ann NY Acad Sci 1153: 131-138
https://dx.doi.org/10.1111/j.1749-6632.2008.03960.x
Yu, X.; Gimsa, U.; Wester-Rosenlöf, L.; Kanitz, E.; Otten, W.; Kunz, M.; Ibrahim, S. M. (2009):
Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res 19 (1): 159-165
https://dx.doi.org/10.1101/gr.078865.108
Henning, J.; Strauss, U.; Wree, A.; Gimsa, J.; Rolfs, A.; Benecke, R.; Gimsa, U. (2008):
Differential astroglial activation in 6-hydroxydopamine models of Parkinson's disease. Neurosci Res 62 (4): 246-253
https://dx.doi.org/10.1016/j.neures.2008.09.001
Strauss, U.; Zhou, F.; Henning, J.; Battefeld, A.; Wree, A.; Köhling, R.; Haas, S.; Benecke, R.; Rolfs, A.; Gimsa, U. (2008):
Increasing extracellular potassium results in subthalamic neuron activity resembling that seen in a 6-hydroxydopamine lesion. J Neurophysiol 99 (6): 2902-2915
https://dx.doi.org/10.1152/jn.00402.2007
Henning, J.; Koczan, D.; Glass, Änne; Karopka, T.; Pahnke, J.; Rolfs, Arndt; Benecke, R.; Gimsa, U. (2007):
Deep brain stimulation in a rat model modulates TH, CaMKIIa and Homer1 gene expression. Eur J Neurosci 25 (1): 239-250
https://dx.doi.org/10.1111/j.1460-9568.2006.05264.x
Mutlu, L.; Brandt, Christine; Kwidzinski, E.; Sawitzki, B.; Gimsa, U.; Mahlo, J.; Aktas, Orhan; Nitsch, Robert; van Zwam, Marloes; Laman, Jon D. (2007):
Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion. Exp Brain Res 178 (4): 542-553
https://dx.doi.org/10.1007/s00221-006-0758-2
Gimsa, U.; Kralj-Iglic, Veronika; Iglic, Ales; Fiedler, Stefan; Zwanzig, Michael; Jonas, E; Gimsa, J. (2007):
Basic cell-cell and cell-surface interactions in liposome and cellular systems. In: Advances in planar lipid bilayers and liposomes Elsevier, (ISSN 1554-4516) (5): 229-252
Gimsa, U.; Iglic, Ales; Fiedler, Stefan; Zwanzig, Michael; Kralj-Iglic, Veronika; Jonas, E; Gimsa, J. (2007):
Actin is not required for nanotubular protrusions of primary astrocytes grown on metal nano-lawn. Mol Membr Biol 24 (3): 243-255
https://dx.doi.org/10.1080/09687860601141730
Gimsa, U.; Scheunemann, Anke; Wachner, Derk; Sakowski, Jan; Köster, Philipp; Gimsa, J. (2006):
Effekte hochfrequenter elektromagnetischer Felder auf zellulärer Ebene - eine Literaturstudie Shaker-Verlag, (ISBN 3-8322-5251-7): 1-89
Mix, Eilhard; Ibrahim, Saleh M.; Glass, Änne; Mazon-Pelaez, Ignacio; Vogler, Susanne; Koczan, D.; Gimsa, U.; Bansemer, S.; Scheel, M.; Karopka, T. (2006):
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE. J Autoimmun 27 (4): 251-265
https://dx.doi.org/10.1016/j.jaut.2006.09.006
Gärtner, S.; Hoff, Holger; Gimsa, U.; Burmester, Gerd-Rüdiger; Brunner-Weinzierl, M. C. (2006):
CD25 regulatory T cells determine secondary but not primary remission in EAE: Impact on long-term disease progression. J Neuroimmunol 172 (1-2): 73-84
https://dx.doi.org/10.1016/j.jneuroim.2005.11.003
Seehuus, Siri-Christine; Norberg, Kari; Gimsa, U.; Krekling, Trygve; Amdam, Gro (2006):
Reproductive protein protects sterile honey-bee workers from oxidative stress. P Natl Acad Sci USA 103 (4): 962-967
https://dx.doi.org/10.1073/pnas.0502681103
Gimsa, U.; Schreiber, Ute; Habel, Beate; Flehr, Jürgen; van Rienen, U.; Gimsa, J. (2006):
Matching geometry and stimulation parameters of electrodes for deep brain stimulation experiments - Numerical considerations. J Neurosci Meth 150 (2): 212-227
https://dx.doi.org/10.1016/j.jneumeth.2005.06.013