PD Dr. sc. agr. habil. Siriluck Wimmers
Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
- miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
- Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene
Lebenslauf
- seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
- 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
- 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
- 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
- 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der Universität Chiang Mai, Thailand
Lehre
Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn
Publikationen
Günther, J.; Petzl, W.; Bauer, I.; Ponsuksili, S.; Zerbe, H.; Schuberth, H.-J.; Brunner, R. M.; Seyfert, H.-M. (2017):
Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection. Sci Rep-UK 7: 4811,1-14
https://dx.doi.org/10.1038/s41598-017-05107-4
Reyer, H.; Shirali, M.; Ponsuksili, S.; Muràni, E.; Varley, P. F.; Jensen, J.; Wimmers, K. (2017):
Exploring the genetics of feed efficiency and feeding behaviour traits in a pig line highly selected for performance characteristics. Mol Genet genomics 292 (5): 1001-1011
https://dx.doi.org/10.1007/s00438-017-1325-1
Oster, M.; Trakooljul, N.; Reyer, H.; Zeyner, A.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Sex-specific muscular maturation responses following prenatal exposure to methylation-related micronutrients in pigs. Nutrients 9 (1): 74-86
https://dx.doi.org/10.3390/nu9010074
Friedrich, J.; Brand, B.; Graunke, K. L.; Langbein, J.; Schwerin, M.; Ponsuksili, S. (2017):
Adrenocortical expression profiling of cattle with distinct juvenile temperament types. Behav Genet 47 (1): 102-113
https://dx.doi.org/10.1007/s10519-016-9816-0
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2016):
Genetically regulated hepatic transcripts and pathways orchestrate haematological, biochemical and body composition traits. Sci Rep-UK 6: 39614, 1-13
https://dx.doi.org/10.1038/srep39614
Reyer, H.; Ponsuksili, S.; Kanitz, E.; Pöhland, R.; Wimmers, K.; Muràni, E. (2016):
A natural mutation in helix 5 of the ligand binding domain of glucocorticoid receptor enhances receptor-ligand interaction. Plos One 11 (10): e0164628, 1-15
https://dx.doi.org/10.1371/journal.pone.0164628
Liu, X.; Trakooljul, N.; Muràni, E.; Krischek, C.; Schellander, K.; Wicke, M.; Wimmers, K.; Ponsuksili, S. (2016):
Molecular changes in mitochondrial respiratory activity and metabolic enzyme activity in muscle of four pig breeds with distinct metabolic types. J Bioenerg Biomembr 48 (1): 55-65
https://dx.doi.org/10.1007/s10863-015-9639-3
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Immediate and long-term transcriptional response of hind muscle tissue to transient variation of incubation temperature in broilers. BMC Genomics 17: 323, 1-13
https://dx.doi.org/10.1186/s12864-016-2671-9
Muràni, E.; Ponsuksili, S.; Jaeger, A.; Görres, A.; Tuchscherer, A.; Wimmers, K. (2016):
A naturally hypersensitive glucocorticoid receptor elicits a compensatory reduction of hypothalamus-pituitary-adrenal axis activity early in ontogeny. Open Biol 6 (7): 150193, 1-11
https://dx.doi.org/10.1098/rsob.150193
Ponsuksili, S.; Reyer, H.; Trakooljul, N.; Muràni, E.; Wimmers, K. (2016):
Single- and Bayesian multi-marker genome-wide association for haematological parameters in pigs. Plos One 11 (7): e0159212, 1-14
https://dx.doi.org/10.1371/journal.pone.0159212
Liu, X.; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2016):
MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities. BMC Genomics 17: 531, 1-14
https://dx.doi.org/10.1186/s12864-016-2850-8
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Transient shifts of incubation temperature reveal immediate and long-term transcriptional response in chicken breast muscle underpinning resilience and phenotypic plasticity. Plos One 11 (9): e0162485, 1-17
https://dx.doi.org/10.1371/journal.pone.0162485
Brand, B.; Scheinhardt, M. O.; Friedrich, J.; Zimmer, D.; Reinsch, N.; Ponsuksili, S.; Schwerin, M.; Ziegler, A. (2016):
Adrenal cortex expression quantitative trait loci in a German Holstein x Charolais cross (Erratum in 17: 148). BMC Genet 17: 135, 1-11
https://dx.doi.org/10.1186/s12863-016-0442-x
Ohde, D.; Moeller, M.; Brenmoehl, J.; Walz, C.; Ponsuksili, S.; Schwerin, M.; Fuellen, G.; Hoeflich, A. (2016):
Advanced running performance by genetic predisposition in male Dummerstorf marathon mice (DUhTP) reveals higher sterol regulatory element-binding protein (SREBP) related mRNA expression in the liver and higher serum levels of progesterone. Plos One 11 (1): e0146748, 1-16
https://dx.doi.org/10.1371/journal.pone.0146748
Oster, M.; Just, F.; Büsing, K.; Wolf, C.; Polley, C.; Vollmar, B.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2016):
Toward improved phosphorus efficiency in monogastrics - interplay of serum, minerals, bone and immune system after divergent dietary phosphorus supply in swine. Am J Physiol-Reg I 310 (10): R917-R925
https://dx.doi.org/10.1152/ajpregu.00215.2015
Friedrich, J.; Brand, B.; Ponsuksili, S.; Graunke, K. L.; Langbein, J.; Knaust, J.; Kühn, C.; Schwerin, M. (2016):
Detection of genetic variants affecting cattle behaviour and their impact on milk production: a genome-wide association study. Anim Genet 47 (1): 12-18
https://dx.doi.org/10.1111/age.12371
Komolka, K.; Ponsuksili, S.; Albrecht, E.; Kühn, C.; Wimmers, K.; Maak, S. (2016):
Gene expression profile of Musculus longissimus dorsi in bulls of a Charolais X Holstein F2-cross with divergent intramuscular fat content. Genomics Data 7: 131-133
https://dx.doi.org/10.1016/j.gdata.2015.12.023
Albrecht, E.; Komolka, K.; Ponsuksili, S.; Gotoh, T.; Wimmers, K.; Maak, S. (2016):
Transcriptome profiling of Musculus longissimus dorsi in two cattle breeds with different intramuscular fat deposition. Genomics Data 7: 109-111
https://dx.doi.org/10.1016/j.gdata.2015.12.014
Görres, A.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2016):
Genetic variation of the porcine NR5A1 is associated with meat color. J APPL Genet 57 (1): 81-89
https://dx.doi.org/10.1007/s13353-015-0289-2
Oster, M.; Nuchchanart, W.; Trakooljul, N.; Muràni, E.; Zeyner, A.; Wirthgen, E.; Hoeflich, A.; Ponsuksili, S.; Wimmers, K. (2016):
Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight. Eur J Nutr 55 (4): 1717-1727
https://dx.doi.org/10.1007/s00394-015-0990-2