PD Dr. sc. agr. habil. Siriluck Wimmers
Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
- miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
- Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene
Lebenslauf
- seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
- 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
- 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
- 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
- 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der Universität Chiang Mai, Thailand
Lehre
Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn
Publikationen
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
https://doi.org/10.1186/s12864-019-5880-1
Gley, K.; Murani, E.; Haack, F.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behav Brain Res 372: 112038, 1-13
https://doi.org/10.1016/j.bbr.2019.112038
Sajjanar, B.; Trakooljul, N.; Wimmers, K.; Ponsuksili, S. (2019):
DNA methylation analysis of porcine mammary epithelial cells reveals differentially methylated loci associated with immune response against Escherichia coli challenge. BMC Genomics 20: 623, 1-15
https://doi.org/10.1186/s12864-019-5976-7
Sajjanar, B.; Siengdee, P.; Trakooljul, N.; Liu, X; Kalbe, C.; Wimmers, K.; Ponsuksili, S. (2019):
Cross-talk between energy metabolism and epigenetics during temperature stress response in C2C12 myoblasts. Int J Hyperther 36 (1): 776-784
https://doi.org/10.1080/02656736.2019.1639834
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
https://doi.org/10.1080/15476286.2019.1657743
Gley, K.; Muráni, E.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Transcriptome profiles of hypothalamus and adrenal gland linked to haplotype related to coping behavior in pigs. Sci Rep-UK 9: 13038, 1-14
https://doi.org/10.1038/s41598-019-49521-2
Muráni, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2019):
Transcriptome responses to dexamethasone depending on dose and glucocorticoid receptor sensitivity in the liver. Front Genet 10: 559, 1-12
https://doi.org/10.3389/fgene.2019.00559
Gerlinger, Ch.; Oster, M.; Borgelt, L.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Polley, C.; Vollmar, B.; Reichel, M.; Wolf, P; Wimmers, K. (2019):
Physiological and transcriptional responses in weaned piglets fed diets with varying phosphorus and calcium levels. Nutrients 11 (2): 436, 1-15
https://doi.org/10.3390/nu11020436
Sokolov, E. P.; Markert, S.; Hinzke, T.; Hirschfeld, C.; Becher, D.; Ponsuksili, S.; Sokolova, I. M. (2019):
Effects of hypoxia-reoxygenation stress on mitochondrial proteome and bioenergetics of the hypoxia-tolerant marine bivalve Crassostrea gigas. J Proteomics 194: 99-111
https://doi.org/10.1016/j.jprot.2018.12.009
Naraballobh, W; Trakooljul, N.; Muráni, E.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2018):
miRNAs regulate acute transcriptional changes in broiler embryos in response to modification of incubation temperature. Sci Rep-UK 8: 11371, 1-12
https://doi.org/10.1038/s41598-018-29316-7
Reyer, H.; Metzler-Zebeli, B.U.; Trakooljul, N.; Oster, M.; Muráni, E.; Ponsuksili, S.; Hadlich, F.; Wimmers, K. (2018):
Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens. Sci Rep-UK 8: 12903, 1-9
https://doi.org/10.1038/s41598-018-31072-7
Reyer, H.; Oster, M.; Magowan, E.; Muráni, E.; Sauerwein, H.; Dannenberger, D.; Kuhla, B.; Ponsuksili, S.; Wimmers, K. (2018):
Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients. Physiol Genomics 50 (9): 726-734
Henry Reyer,
Michael Oster,
Eduard Muráni,
Dirk Dannenberger,
Björn Kuhla,
Siriluck Wimmers,
Klaus Wimmers
https://doi.org/10.1152/physiolgenomics.00021.2018
Just, F.; Oster, M.; Büsing, K.; Borgelt, L.; Muráni, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2018):
Lowered dietary phosphorus affects intestinal and renal gene expression to maintain mineral homeostasis with immunomodulatory implications in weaned piglets. BMC Genomics 19: 207, 1-11
https://doi.org/10.1186/s12864-018-4584-2
Just, F.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Oster, M.; Wimmers, K. (2018):
Genetic variants of major genes contributing to phosphate and calcium homeostasis and their association with serum parameters in pigs. J Appl Genet 59 (3): 325-333
https://doi.org/10.1007/s13353-018-0449-2
Oster, M.; Gerlinger, Ch.; Heide, K.; Just, F.; Borgelt, L.; Wolf, C.; Polley, C.; Vollmar, B.; Muráni, E.; Ponsuksili, S.; Wimmers, K. (2018):
Lower dietary phosphorus supply in pigs match both animal welfare aspects and resource efficiency. Ambio 47 (Suppl. 1): 20-29
https://doi.org/10.1007/s13280-017-0969-8
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2017):
Genetic architecture and regulatory impact on hepatic microRNA expression linked to immune and metabolic traits. Open Biol 7 (11): 170101, 1-11
https://dx.doi.org/10.1098/rsob.170101
Liu, X; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
Mitochondrial-nuclear crosstalk, haplotype and copy number variation distinct in muscle fiber type, mitochondrial respiratory and metabolic enzyme activities. Sci Rep-UK 7: 14024, 1-12
https://dx.doi.org/10.1038/s41598-017-14491-w
Jaeger, A.; Hadlich, F.; Kemper, N.; Lübke-Becker, A.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
MicroRNA expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli in vitro. BMC Genomics 18: 660, 1-14
https://dx.doi.org/10.1186/s12864-017-4070-2
Reyer, H.; Varley, P. F.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Genetics of body fat mass and related traits in a pig population selected for leanness. Sci Rep-UK 7: 9118, 1-9
https://dx.doi.org/10.1038/s41598-017-08961-4
Reyer, H.; Oster, M.; Magowan, E.; Dannenberger, D.; Ponsuksili, S.; Wimmers, K. (2017):
Strategies towards improved feed efficiency in pigs comprise molecular shifts in hepatic lipid and carbohydrate metabolism. Int J Mol Sci 18 (8): 1674, 1-15
https://dx.doi.org/10.3390/ijms18081674