PD Dr. sc. agr. habil. Siriluck Wimmers

Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
  • miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
  • Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene

Lebenslauf

  • seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
  • 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
  • 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
  • 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
  • 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der  Universität Chiang Mai, Thailand

Lehre

Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn

Publikationen

Srikanchai, T.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2010):
Association of ZYX polymorphisms with carcass and meat quality traits in commercial pigs. Meat Sci 84 (1): 159-164
https://dx.doi.org/10.1016/j.meatsci.2009.08.042
Muràni, E.; Ponsuksili, S.; Seyfert, H.-M.; Shi, X.; Wimmers, K. (2009):
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing. BMC Mol Biol 10 (96): 1-11
https://dx.doi.org/10.1186/1471-2199-10-96
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2009):
Porcine muscle sensory attributes associate with major changes in gene networks invoving CAPZB, ANKDR1, and CTBP2. Funct Integr Genomic 9 (4): 455-471
https://dx.doi.org/10.1007/s10142-009-0131-1
Schwerin, M.; Janczyk, P.; Ponsuksili, S.; Walz, C.; Souffrant, W.-B. (2009):
Effects of plant extract and natural substance food additives on stress and immune response in weaning piglets. Archiva Zootechnica 12 (4): 5-21
Muràni, E.; Ponsuksili, S.; Srikanchai, T.; Maak, S.; Wimmers, K. (2009):
Expression of the porcine adrenergic receptor beta 2 gene in longissimus dorsi muscle is affected by cis-regulatory DNA variation. Anim Genet 40 (1): 80-89
https://dx.doi.org/10.1111/j.1365-2052.2008.01811.x
Wimmers, K.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2009):
QTL for traits related to humoral immune response estimated from data of a porcine F2 resource population. INT J IMMUNOGENET 36 (3): 141-151
https://dx.doi.org/10.1111/j.1744-313X.2009.00838.x
Tetzlaff, S.; Muràni, E.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2009):
Differential expression of growth factors and their receptors points out their involvement in the inverted teat defect in pigs. J Anim Sci 87 (11): 3451-3457
https://dx.doi.org/10.2527/jas.2008-1660
Tetzlaff, S.; Jonas, E; Phatsara, C.; Muràni, E.; Ponsuksili, S.; Schellander, K.; Wimmers, K. (2009):
Evidence for association of lymphoid enhancer-binding factor-1 (LEF1) with the number of functional and inverted teats in pigs. Cytogenet Genome Res 124 (2): 139-146
https://dx.doi.org/10.1159/000207521
Tetzlaff, S.; Chomdej, S.; Jonas, E; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schellander, K.; Wimmers, K. (2009):
Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs. J Anim Breed Genet 126 (3): 237-241
https://dx.doi.org/10.1111/j.1439-0388.2008.00781.x
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Jonas, E; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2008):
Expression profiling of muscle reveals transcripts differentially expressed in muscle that affect water-holding capacity of pork. J Agr Food Chem 56 (21): 10311-10317
https://dx.doi.org/10.1021/jf800881y
Wimmers, K.; Ngu, N.T.; Jennen, D.; Tesfaye, D.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2008):
Relationship between myosin heavy chain isoform expression and muscling in several diverse pig breeds. J Anim Sci 86 (4): 795-803
https://dx.doi.org/10.2527/jas.2006-521
Wimmers, K.; Kumar, K.G.; Schellander, K.; Ponsuksili, S. (2008):
Porcine IL12A and IL12B gene mapping, variation and evidence of association with lytic complement and blood leucocyte proliferation traits. INT J IMMUNOGENET 35 (1): 75-85
https://dx.doi.org/10.1111/j.1744-313X.2007.00742.x
Ponsuksili, S.; Jonas, E; Muràni, E.; Phatsara, C.; Srikanchai, T.; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2008):
Trait correlated expression combined with expression QTL analysis reveals biological pathways and candidate genes affecting water holding capacity of muscle. BMC Genomics 9: 367
https://dx.doi.org/10.1186/1471-2164-9-367
Liu, G.; Kim, EJ; Jonas, E; Wimmers, K.; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Tholen, E.; Jüngst, H.; Tesfaye, D.; Ji Lan Chen, J.L; Schellander, K. (2008):
Combined line-cross and half-sib QTL analysis in Duroc-Pietrain population. Mamm Genome 19 (6): 429-438
https://dx.doi.org/10.1007/s00335-008-9132-y
Phatsara, C.; Jonas, E; Yammuen-art, S; Buschbell, K; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Wimmers, K. (2008):
Physiological interactions between the endocrine and immune systems shown in gene analysis in pigs. Developments in Biologicals 132: 161-167
Ponsuksili, S.; Muràni, E.; Wimmers, K. (2008):
Porcine genome-wide gene expression in response to tetanus toxoid vaccine. Developments in Biologicals 132: 185-195
Wimmers, K.; Jonas, E; Schreinemachers, H.-J.; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Phatsara, C. (2008):
Verification of chromosomal regions affecting the innate immunity in pigs using linkage mapping.. Developments in Biologicals 132: 279-286
Jonas, E; Schreinemachers, H.-J.; Kleinwächter, T.; Ün, G.; Oltmanns, I.; Tetzlaff, S.; Jennen, D.; Tesfaye, D.; Ponsuksili, S.; Muràni, E.; Jüngst, H.; Tholen, E.; Schellander, K.; Wimmers, K. (2008):
QTL for the heritable inverted teat defect in pigs. Mamm Genome 19 (2): 127-138
https://dx.doi.org/10.1007/s00335-007-9086-5
Thumdee, P.; Ponsuksili, S.; Muràni, E.; Nganvongpanit, K.; Gehrig, B; Tesfaye, D.; Gilles, M.; Hoelker, M; Jennen, D.; Griese, J.; Schellander, K.; Wimmers, K. (2007):
Expression of the prion protein gene (PRNP) and cellular prion protein (PrPc) in cattle and sheep foetuses and maternal tissues during pregnancy. Gene Expression 13 (4-5): 283-297
https://doi.org/10.3727/000000006780666984
Muràni, E.; Ponsuksili, S.; Wimmers, K. (2007):
Investigation of genetic and epigenetic mechanisms underlying stage- and breed-specific differences in the transcription of SPP1 gene during porcine myogenesis. Arch Tierzucht 50: 49-56