PD Dr. sc. agr. habil. Siriluck Wimmers
Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
- miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
- Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene
Lebenslauf
- seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
- 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
- 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
- 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
- 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
- 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der Universität Chiang Mai, Thailand
Lehre
Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn
Publikationen
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2010):
Functional genomics and genetical genomics approaches towards elucidating networks of genes affecting meat performance in pigs. Briefings in Functional Genomics 9: 251-258
https://dx.doi.org/10.1093/bfgp/elq003
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2010):
Expression QTL and their applications in genetic improvement in farm animals.
https://dx.doi.org/10.1079/PAVSNNR20105012
Ponsuksili, S.; Muràni, E.; Schwerin, M.; Schellander, K.; Wimmers, K. (2010):
Identification of expression QTL (eQTL) of genes expressed in porcine M. longissimus dorsi and associated with meat quality traits. BMC Genomics 11: 572
https://dx.doi.org/10.1186/1471-2164-11-572
Taubert, A.; Wimmers, K.; Ponsuksili, S.; Jimenez, C.A; Zahner, H.; Hermosilla, C. (2010):
Microarray-based transcriptional profiling of Eimeria bovis-infected bovine endothelial host cells . Vet Res 41 (5): 70
https://dx.doi.org/10.1051/vetres/2010041
Uddin, M. J.; Grosse-Brinkhaus, C; Cinar, U; Jonas, E; Tesfaye, D.; Tholen, E.; Jüngst, H.; Looft, C.; Ponsuksili, S.; Wimmers, K.; Phatsara, C.; Schellander, K. (2010):
Mapping of quantitative trait loci for mycoplasma and tetanus antibodies and interferon-gamma in a porcine F-2 Duroc x Pietrain resource population. Mamm Genome 21 (7): 409-418
https://dx.doi.org/10.1007/s00335-010-9269-3
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2010):
Pre- and postnatal differential gene expression with relevance for meat and carcass traits in pigs - a review. Anim Sci Pap Rep 28 (2): 115-122
Naraballobh, W; Chomdej, S.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2010):
Annotation and in silico localization of the Affymetrix GeneChip Porcine Genome Array. Arch Tierzucht 53: 230-238
Srikanchai, T.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2010):
Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds. Mol Biol Rep 37 (1): 595-601
https://dx.doi.org/10.1007/s11033-009-9856-0
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2010):
Expression quantitative trait loci analysis of genes in porcine muscle by quantitative real-time RT-PCR compared to microarray data. Heredity 105 (3): 309-317
https://dx.doi.org/10.1038/hdy.2010.5
Muràni, E.; Ponsuksili, S.; D´Eath, R.; Turner, S.P.; Evans, G.; Foury, A.; Kurt, E.; Thölking, L.; Klont, R.; Mormède, P.; Wimmers, K. (2010):
Transcriptional profiling of the adrenal gland for the identification of genes and pathways associated with stress response and aggressive behaviour. In: 32th ISAG conference proceedings (International Society for Animal Genetics, Hrsg.): 108
Muràni, E.; Ponsuksili, S.; D´Eath, R.; Turner, S.P.; Kurt, E.; Evans, G.; Thölking, L.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2010):
Association of HPA axis-related genetic variation with stress reactivity and aggressive behaviour in pigs. BMC Genet 11 (74): 1-11
https://dx.doi.org/10.1186/1471-2156-11-74
Srikanchai, T.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2010):
Association of ZYX polymorphisms with carcass and meat quality traits in commercial pigs. Meat Sci 84 (1): 159-164
https://dx.doi.org/10.1016/j.meatsci.2009.08.042
Muràni, E.; Ponsuksili, S.; Seyfert, H.-M.; Shi, X.; Wimmers, K. (2009):
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing. BMC Mol Biol 10 (96): 1-11
https://dx.doi.org/10.1186/1471-2199-10-96
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2009):
Porcine muscle sensory attributes associate with major changes in gene networks invoving CAPZB, ANKDR1, and CTBP2. Funct Integr Genomic 9 (4): 455-471
https://dx.doi.org/10.1007/s10142-009-0131-1
Schwerin, M.; Janczyk, P.; Ponsuksili, S.; Walz, C.; Souffrant, W.-B. (2009):
Effects of plant extract and natural substance food additives on stress and immune response in weaning piglets. Archiva Zootechnica 12 (4): 5-21
Muràni, E.; Ponsuksili, S.; Srikanchai, T.; Maak, S.; Wimmers, K. (2009):
Expression of the porcine adrenergic receptor beta 2 gene in longissimus dorsi muscle is affected by cis-regulatory DNA variation. Anim Genet 40 (1): 80-89
https://dx.doi.org/10.1111/j.1365-2052.2008.01811.x
Wimmers, K.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2009):
QTL for traits related to humoral immune response estimated from data of a porcine F2 resource population. INT J IMMUNOGENET 36 (3): 141-151
https://dx.doi.org/10.1111/j.1744-313X.2009.00838.x
Tetzlaff, S.; Muràni, E.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2009):
Differential expression of growth factors and their receptors points out their involvement in the inverted teat defect in pigs. J Anim Sci 87 (11): 3451-3457
https://dx.doi.org/10.2527/jas.2008-1660
Tetzlaff, S.; Jonas, E; Phatsara, C.; Muràni, E.; Ponsuksili, S.; Schellander, K.; Wimmers, K. (2009):
Evidence for association of lymphoid enhancer-binding factor-1 (LEF1) with the number of functional and inverted teats in pigs. Cytogenet Genome Res 124 (2): 139-146
https://dx.doi.org/10.1159/000207521
Tetzlaff, S.; Chomdej, S.; Jonas, E; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schellander, K.; Wimmers, K. (2009):
Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs. J Anim Breed Genet 126 (3): 237-241
https://dx.doi.org/10.1111/j.1439-0388.2008.00781.x