PD Dr. sc. agr. Siriluck Wimmers

Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Integrative Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
  • miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
  • Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene

Lebenslauf

  • seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
  • 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
  • 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
  • 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
  • 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der  Universität Chiang Mai, Thailand

Lehre

Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn

Publikationen

Omotoso, A. O.; Reyer, H.; Oster, M.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2023):
Broiler physiological response to low phosphorus diets at different stages of production. Poultry Sci 102 (2): 102351, 1-38
Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2023):
The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains. Poultry Sci 102 (1): 102256, 1-14
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Wimmers, K. (2023):
Jejunal Microbiota of Broilers fed varying Levels of Mineral Phosphorus [epublished ahead of print]. Poultry Sci
Brenmoehl, J.; Brosig, E.; Trakooljul, N.; Walz, C.; Ohde, D.; Noce, A.; Walz, M.; Langhammer, M.; Petkov, S.; Röntgen, M.; Maak, S.; Galuska, C. E.; Fuchs, B.; Kuhla, B.; Ponsuksili, S.; Wimmers, K.; Hoeflich, A. (2023):
Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC) - a Possible Role of Lactate Dehydrogenase in Metabolic Flexibility. Cells-Basel 12 (15): 1925, 1-21
Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2023):
RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken. Evol Appl 16 (6): 1135-1153
Honerlagen, H.; Reyer, H.; Abousoliman, I.; Segelke, D.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2023):
Microbial signature inferred from genomic breeding selection on milk urea concentration and its relation to proxies of nitrogen-utilization efficiency in Holsteins. J Dairy Sci 106 (7): 4682-4697
Honerlagen, H.; Reyer, H.; Segelke, D.; Müller, C. B. M.; Prahl, M. C.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2022):
Ruminal background of predisposed milk urea (MU) concentration in Holsteins. Front microbiol 13: 939711, 1-18
Hasan, M.; Oster, M.; Reyer, H.; Ponsuksili, S.; Murani, E.; Wolf, P.; Fischer, D.-C.; Wimmers, K. (2022):
Tissue-Wide Expression of Genes Related to Vitamin D Metabolism and FGF23 Signaling following Variable Phosphorus Intake in Pigs. METABOLITES 12 (8): 729, 1-15
Adzigbli, L.; Sokolov, E. P.; Wimmers, K.; Sokolova, I. M.; Ponsuksili, S. (2022):
Effects of hypoxia and reoxygenation on mitochondrial functions and transcriptional profles of isolated brain and muscle porcine cells. Sci Rep-UK 12: 19881, 1-17
Metzger, K.; Kalbe, C.; Siengdee, P.; Ponsuksili, S. (2022):
The effects of temperature and donor piglet age on the transcriptomic profile and energy metabolism of myoblasts. Front Physiol 13: 979283, 1-13
Iqbal, M. A.; Reyer, H.; Oster, M.; Hadlich, F.; Trakooljul, N.; Perdomo-Sabogal, A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2022):
Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens. Front Genet 13: 858232, 1-20
Sarais, F.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2022):
tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research. NON-CODING RNA 8 (3): 37, 1-19
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity. Sci Rep-UK 12: 16293, 1-13
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER 13: 24, 1-14
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
Adzigbli, L.; Sokolov, E. P.; Ponsuksili, S.; Sokolova, I. M. (2022):
Tissue- and substrate-dependent mitochondrial responses to acute hypoxia–reoxygenation stress in a marine bivalve (Crassostrea gigas). J Exp Biol 225 (1): 243304, 1-13
https://doi.org/10.1242/jeb.243304
Abu Risha, M.; Ali, A.; Siengdee, P.; Trakooljul, N.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2022):
Insights into molecular pathways and fatty acid membrane composition during the temperature stress response in the murine C2C12 cell model. Sci Total Environ 807 (3): 151019, 1-13
https://doi.org/10.1016/j.scitotenv.2021.151019
Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418