PD Dr. sc. agr. Siriluck Wimmers

+49 38208 68-702
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Genombiologie
Abteilungsleitung Funktionale Genomanalyse
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekulargenetik und Expression der Fleischqualität und weiterer Leistungseigenschaften landwirtschaftlicher Nutztiere
  • miRNA regulatorische Netzwerke des Energiemetabolismus und der Fleischqualität in Muskelzellen
  • Eigenschaftsabhängige Variation der Genotyp-Phänotyp Beziehung auf molekularer Ebene

Lebenslauf

  • seit 2014: Abteilungsleitung Funktionale Genomanalyse im Institut Genombiologie am FBN
  • 2004-2013: Oberassistentin Funktionale Genomanalyse , FBN
  • 2003: Habilitation, venia legendi an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 1997-2003: Wissenschaftliche Mitarbeiterin an der Agrarwissenschaftlichen Fakultät der Universität Bonn
  • 01/1997: Assistenzprofessor im Institut für Tierwissenschaften an der Agrarwissenschaftlichen Fakultät der Universität Chiang Mai, Thailand
  • 1990-1995: DAAD-Stipendiatin, Promotion am Institut für Tierwissenschaften der TU Berlin
  • 1987-1997: Dozentin am Institut für Tierwissenschaften der Agrarwissenschaftlichen Fakultät an der  Universität Chiang Mai, Thailand

Lehre

Vorlesungen und Seminare an der Agrarwissenschaftlichen Fakultät der Universität Bonn

Publikationen

Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2023):
RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken [epublished ahead of print]. Evol Appl
https://doi.org/10.1111/eva.13557
Honerlagen, H.; Reyer, H.; Abousoliman, I.; Segelke, D.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2023):
Microbial signature inferred from genomic breeding selection on milk urea concentration and its relation to proxies of nitrogen-utilization efficiency in Holsteins [epublished ahead of print]. J Dairy Sci
https://doi.org/10.3168/jds.2022-22935
Honerlagen, H.; Reyer, H.; Segelke, D.; Müller, C. B. M.; Prahl, M.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2022):
Ruminal background of predisposed milk urea (MU) concentration in Holsteins. Front microbiol 13: 939711, 1-18
https://doi.org/10.3389/fmicb.2022.939711
Hasan, M.; Oster, M.; Reyer, H.; Ponsuksili, S.; Murani, E.; Wolf, P.; Fischer, D.-C.; Wimmers, K. (2022):
Tissue-Wide Expression of Genes Related to Vitamin D Metabolism and FGF23 Signaling following Variable Phosphorus Intake in Pigs. METABOLITES 12 (8): 729, 1-15
https://doi.org/10.3390/metabo12080729
Omotoso, A. O.; Reyer, H.; Oster, M.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2022):
Broiler physiological response to low phosphorus diets at different stages of production [epublished ehead of print]. Poultry Sci
https://doi.org/10.1016/j.psj.2022.102351
Adzigbli, L.; Sokolov, E. P.; Wimmers, K.; Sokolova, I. M.; Ponsuksili, S. (2022):
Effects of hypoxia and reoxygenation on mitochondrial functions and transcriptional profles of isolated brain and muscle porcine cells. Sci Rep-UK 12: 19881, 1-17
https://doi.org/10.1038/s41598-022-24386-0
Metzger, K.; Kalbe, C.; Siengdee, P.; Ponsuksili, S. (2022):
The effects of temperature and donor piglet age on the transcriptomic profile and energy metabolism of myoblasts. Front Physiol 13: 979283, 1-13
https://doi.org/10.3389/fphys.2022.979283
Iqbal, M. A.; Reyer, H.; Oster, M.; Hadlich, F.; Trakooljul, N.; Perdomo-Sabogal, A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2022):
Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens. Front Genet 13: 858232, 1-20
https://doi.org/10.3389/fgene.2022.858232
Sarais, F.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2022):
tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research. NON-CODING RNA 8 (3): 37, 1-19
https://doi.org/10.3390/ncrna8030037
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity. Sci Rep-UK 12: 16293, 1-13
https://doi.org/10.1038/s41598-022-20682-x
Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2022):
The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains [epublished ahead of print]. Poultry Sci
https://doi.org/10.1016/j.psj.2022.102256
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER 13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Adzigbli, L.; Sokolov, E. P.; Ponsuksili, S.; Sokolova, I. M. (2022):
Tissue- and substrate-dependent mitochondrial responses to acute hypoxia–reoxygenation stress in a marine bivalve (Crassostrea gigas). J Exp Biol 225 (1): 243304, 1-13
https://doi.org/10.1242/jeb.243304
Abu Risha, M.; Ali, A.; Siengdee, P.; Trakooljul, N.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2022):
Insights into molecular pathways and fatty acid membrane composition during the temperature stress response in the murine C2C12 cell model. Sci Total Environ 807 (3): 151019, 1-13
https://doi.org/10.1016/j.scitotenv.2021.151019
Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
https://doi.org/10.1016/j.gpb.2020.06.007
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Ponsuksili, S.; Oster, M.; Reyer, H.; Hadlich, F.; Trakooljul, N.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2021):
Genetic regulation and heritability of miRNA and mRNA expression link to phosphorus utilization and gut microbiome. Open Biol 11 (2): 200182, 1-11
https://doi.org/10.1098/rsob.200182