Dr. rer. nat. Rosemarie Weikard
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Genombiologie
Abteilung Genomphysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Institut für Genombiologie
Abteilung Genomphysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Publikationen
Nolte, W.; Weikard, R.; Kühn, C. (2023):
Identifizierung und Charakterisierung der Rolle langer nichtkodierender RNA (lncRNA) bei der Genregulation von Stoffwechselprozessen beim Rind. Zuchtungskunde 95 (1): 34-43
Nolte, W.; Weikard, R.; Albrecht, E.; Hammon, H. M.; Kühn, C. (2022):
Metabogenomic analysis to functionally annotate the regulatory role of long non-coding RNAs in the liver of cows with different nutrient partitioning phenotype. Genomics 114 (1): 202-214
https://doi.org/10.1016/j.ygeno.2021.12.004
Chitneedi, P.; Weikard, R.; Arranz, J. J.; Martínez-Valladares, M.; Kühn, C.; Gutiérrez-Gil, B. (2021):
Identification of Regulatory Functions of LncRNAs Associated With T. circumcincta Infection in Adult Sheep. Front Genet 12: 685341, 1-18
https://doi.org/10.3389/fgene.2021.685341
Becker, D.; Weikard, R.; Hadlich, F.; Kühn, C. (2021):
Single-cell RNA sequencing of freshly isolated bovine milk cells and cultured primary mammary epithelial cells. Sci Data 8: 177, 1-9
Becker, D.; Weikard, R.; Schulze, C.; Wohlsein, P.; Kühn, C. (2020):
A 50-kb deletion disrupting the RSPO2 gene is associated with tetradysmelia in Holstein Friesian cattle. Genet Sel Evol 62: 68, 1-13
Knaust, J.; Weikard, R.; Albrecht, E.; Brunner, R. M.; Günther, J.; Kühn, C. (2020):
Indication of premelanosome protein (PMEL) expression outside of pigmented bovine skin suggests functions beyond eumelanogenesis. Genes-Basel 11 (7): 788,1-13
https://doi.org/10.3390/genes11070788
Nolte, W.; Weikard, R.; Brunner, R. M.; Albrecht, E.; Hammon, H. M.; Reverter, A.; Kühn, C. (2020):
Identification and annotation of potential function of regulatory antisense long non-coding RNAs related to feed efficiency in Bos taurus bulls. Int J Mol Sci 21 (9): 3292,1-14
https://doi.org/10.3390/ijms21093292
Heimes, A.; Brodhagen, J.; Weikard, R.; Seyfert, H.-M.; Becker, D.; Meyerholz, M. M.; Petzl, W.; Zerbe, H.; Hoedemaker, M.; Rohmeier, L.; Schubert, H-J; Schmicke, M.; Engelmann, S.; Kühn, C. (2020):
Hepatic transcriptome analysis identifies divergent pathogen-specific targeting-strategies to modulate the innate immune system in response to intramammary infection. Front Immunol 11: 715, 1-22
https://doi.org/10.3389/fimmu.2020.00715
Heimes, A.; Brodhagen, J.; Weikard, R.; Becker, D.; Meyerholz, M. M.; Petzl, W.; Zerbe, H.; Schuberth, H.-J.; Hoedemaker, M.; Schmicke, M.; Engelmann, S.; Kühn, C. (2020):
Cows selected for divergent mastitis susceptibility display a differntial liver transcriptome profile after experimental Staphylococcus aureus mammary gland inoculation. J Dairy Sci 103 (7): 6364-6373
https://doi.org/10.3168/jds.2019-17612
Nolte, W.; Weikard, R.; Brunner, R. M.; Albrecht, E.; Hammon, H. M.; Kühn, C. (2019):
Biological network approach for the identification of regulatory long non-coding RNAs associated with metabolic efficiency in cattle. Front Genet 10: 1130, 1-19
https://doi.org/10.3389/fgene2019.01130
Brodhagen, J.; Weikard, R.; Thom, U.; Heimes, A.; Günther, J.; Hadlich, F.; Zerbe, H.; Petzl, W.; Meyerholz, M. M.; Hoedemaker, M.; Schubert, H-J; Engelmann, S.; Kühn, C. (2019):
Development and evaluation of a milk protein transcript depletion method for differential transcriptome analysis in mammary gland tissue. BMC Genomics 20 (1): 400, 1-19
https://doi.org/10.1186/s12864-019-5781-3
Robic, A.; Farault, T.; Djebali, S.; Weikard, R.; Feve, K.; Maman, S.; Kühn, C. (2019):
Analysis of pig transcriptomes suggests a gloal regulation mechanism enabling temporary bursts of circular RNAs. RNA Biol 16 (9): 1190-1204
https://doi.org/10.1080/15476286.2019.1621621
Heimes, A.; Brodhagen, J.; Weikard, R.; Hammon, H. M.; Meyerholz, M. M.; Petzl, W.; Zerbe, H.; Engelmann, S.; Schmicke, M.; Hoedemaker, M.; Schubert, H-J; Kühn, C. (2019):
Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18. BMC Vet Res 15 (1): 241, 1-11
https://doi.org/10.1186/s12917-019-1988-4
Koch, F.; Thom, U.; Albrecht, E.; Weikard, R.; Nolte, W.; Kuhla, B.; Kühn, C. (2019):
Heat stress directly impairs gut integrity and recruits distinct immune cell populations into the bovine intestine. P Natl Acad Sci USA 116 (21): 10333-10338
https://doi.org/10.1073/pnas.1820130116
Weikard, R.; Kühn, C. (2018):
Different mitochondrial DNA copy number in liver and mammary gland of lactating cows with divergent genetic background for milk production. Mol Biol Rep 45 (5): 1209-1218
https://doi.org/10.1007/s11033-018-4273-x
Weikard, R.; Hadlich, F.; Hammon, H. M.; Frieten, D.; Gerbert, C.; Koch, C.; Dusel, G.; Kühn, C. (2018):
Long noncoding RNAs are associated with metabolic and cellular processes in the jejunum mucosa of pre-weaning calves in response to different diets. Oncotarget 9 (30): 21052-21069
https://doi.org/10.18632/oncotarget.24898
Hammon, H. M.; Frieten, D.; Gerbert, C.; Koch, C.; Dusel, G.; Weikard, R.; Kühn, C. (2018):
Different milk diets have substantial effects on the jejunal mucosal immune system of pre-weaning calves, as demonstrated by whole transcriptome sequencing. Sci Rep-UK 8: 1693, 1-14
https://doi.org/10.1038/s41598-018-19954-2
Usman, T.; Hadlich, F.; Demasius, W.; Weikard, R.; Kühn, C. (2017):
Unmapped reads from cattle RNAseq data: a source for missing and misassembled sequences in the reference assemblies and for detection of pathogens in the host. Genomics 109 (1): 36-42
https://dx.doi.org/10.1016/j.ygeno.2016.11.009
Weikard, R.; Demasius, W.; Kühn, C. (2017):
Mining long noncoding RNA in livestock. Anim Genet 48 (1): 3-18
https://dx.doi.org/10.1111/age.12493
Demasius, W.; Weikard, R.; Hadlich, F.; Buitkamp, J.; Kühn, C. (2016):
A novel RNAseq–assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease. BMC Genomics 17: 365, 1-15
https://dx.doi.org/10.1186/s12864-016-2688-0