Dr. Nares Trakooljul

+49 38208 68-702
Leibniz-Institut für Nutztierbiologie (FBN)
Institut für Genombiologie
Abteilung Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Epigenetische Einflüsse auf maternale Ernährung während der Trächtigkeit  auf das Methylom, Transkriptom und die Phänotypen der Nachkommen
  • Funktionelle Rolle der microRNAs in Nutztieren
  • Anwendung von Next Generation Sequencing (NGS) Technologien in der Nutztiergenomik

Lebenslauf

  • seit 2012: Wissenschaftler am Leibniz Institut für Nutztierbiologie (FBN), Dummerstorf
  • 2008–2012: Wissenschaftlicher Mitarbeiter an der North Carolina State University, USA
  • 2005–2008: Postdoc an der University of Delaware, USA
  • 1999–2005: Promotion an der Universität Bonn

Publikationen

Du, S.; Trakooljul, N.; Schoen, J.; Chen, S. (2020):
Does maternal stress affect the early embryonic microenvironment? Impact of long-term cortisol stimulation on the oviduct epithelium. Int J Mol Sci 21 (2): 443, 1-14
Laezer, I.; Palma-Vera, S. E.; Liu, F.; Frank, M.; Trakooljul, N.; Vernunft, A.; Schoen, J.; Chen, S. (2020):
Dynamic profile of EVs in porcine oviductal fluid during the periovulatory period. Reproduction 159 (4): 371-382
Oster, M.; Reyer, H.; Trakooljul, N.; Weber, F. M.; Xi, L.; Muráni, E.; Ponsuksili, S.; Rodehutscord, M.; Bennewitz, J.; Wimmers, K. (2020):
Ileal transcriptome profiles of Japanese quail divergent in phosphorus utilization. Int J Mol Sci 21: 2762, 1-13
Li, Z.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A; Metges, C. C.; Trakooljul, N.; Wimmers, K.; Murani, E. (2020):
A natural Ala610Val substitution causing glucocorticoid receptor hypersensitivity aggravates consequences of endotoxemia. Brain Behav Immun 90: 174-183
Wubuli, A.; Gerlinger, Ch.; Reyer, H.; Oster, M.; Murani, E.; Trakooljul, N.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2020):
Reduced phosphorus intake throughout gestation and lactation of sows is mitigated by transcriptional adaptations in kidney and intestine . BMC Genomics 21: 626, 1-11
Ponsuksili, S.; Reyer, H.; Hadlich, F.; Weber, F. M.; Trakooljul, N.; Oster, M.; Siengdee, P.; Muráni, E.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2020):
Identification of the key molecular drivers of phosphorus utilization based on host miRNA-mRNA and gut microbiome interactions. Int J Mol Sci 21: 2818, 1-18
Webb, L.; Ghaffari, M. H.; Sadri, H.; Schuh, K.; Zamarian, V.; Koch, C.; Trakooljul, N.; Wimmers, K.; Lecchi, C.; Ceciliani, F.; Sauerwein, H. (2020):
Profiling of circulating microRNA and pathway analysis in normal- versus over-conditioned dairy cows during the dry period and early lactation. J Dairy Sci 103 (10): 9534-9547
Hicks, J. A.; Trakooljul, N.; Liu, H. (2019):
Alterations in cellular and viral microRNA and cellular gene expression in Marek's disease virus-transformed T-cell lines treated with sodium butyrate. Poultry Sci 98 (2): 642-652
Horodyska, J.; Reyer, H.; Wimmers, K.; Trakooljul, N.; Lawlor, P. G.; Hamill, R. (2019):
Transcriptome analysis of adipose tissue from pigs divergent in feed efficiency reveals alteration in gene networks related to adipose growth, lipid metabolism, extracellular matrix and immune response. Mol Genet genomics 294: 395-408
Horodyska, J.; Hamill, R.; Reyer, H.; Trakooljul, N.; Lawlor, P. G.; McCormack, U. M.; Wimmers, K. (2019):
RNA-seq of liver from pigs divergent in feed efficiency highlights shifts in macronutrient metabolism, hepatic growth and immune response. Front Genet 10: 117, 1-11
Li, Z.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A; Metges, C. C.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2019):
Kinetics of physiological and behavioural responses in endotoxemic pigs with or without dexamethasone treatment. Int J Mol Sci 20 (6): 1393, 1-15
Muráni, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2019):
Transcriptome responses to dexamethasone depending on dose and glucocorticoid receptor sensitivity in the liver. Front Genet 10: 559, 1-12
Gley, K.; Muráni, E.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Transcriptome profiles of hypothalamus and adrenal gland linked to haplotype related to coping behavior in pigs. Sci Rep-UK 9: 13038, 1-14
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
Sajjanar, B.; Siengdee, P.; Trakooljul, N.; Liu, X; Kalbe, C.; Wimmers, K.; Ponsuksili, S. (2019):
Cross-talk between energy metabolism and epigenetics during temperature stress response in C2C12 myoblasts. Int J Hyperther 36 (1): 776-784
Sajjanar, B.; Trakooljul, N.; Wimmers, K.; Ponsuksili, S. (2019):
DNA methylation analysis of porcine mammary epithelial cells reveals differentially methylated loci associated with immune response against Escherichia coli challenge. BMC Genomics 20: 623, 1-15
Gley, K.; Murani, E.; Haack, F.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behav Brain Res 372: 112038, 1-13
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Methling, K.; Lalk, M.; Murani, E.; Wimmers, K. (2019):
Genetic regulation of liver metabolites and transcripts linking to biochemical-llinical parameters. Front Genet 10: 348, 1-15
Benítez, R.; Trakooljul, N.; Nunez, Y.; Isabel, B.; Murani, E.; de Mercado, E.; Gómez-Izquierdo, E.; Garcia-Casco, J.; López-Bote, C.; Wimmers, K.; Óvilo, C. (2019):
Breed, diet, and interaction effects on adipose tissue transcriptome in Iberian and Duroc pigs fed different energy sources. Genes-Basel 10 (8): 589, 1-24