PD Dr. med. vet. habil. Monika Röntgen
Forschungsinteressen
- Zell- und Muskelbiologie
- Stammzellen und Zell-basierte Landwirtschaft
- Proteinalternativen
- Modulation des Skelettmuskelwachstums
- Probiotika und Antibiotikaersatz
- Myopathien
- Energiestoffwechsel und Mitochondrien
- Zelluläre und epitheliale Transportmechanismen
- Zellkultur und Nährmedien
- Mineralstoffe mit Schwerpunkt Magnesium und Aminosäuren
- Vegetatives Nervensystem
Lebenslauf
- 2013-heute: Leiterin der Abteilung „Wachstum & Entwicklung“ am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf
- 2004-2013: Arbeitsgruppenleiterin am Forschungsinstitut für Nutztier-biologie (FBN) Dummerstorf
- 2003-2004: Wissenschaftliche Oberassistentin (C2) am Institut für Veterinär-Physiologie des FB Veterinärmedizin der Freien Universität Berlin.
- 1993-2003: Wissenschaftliche Assistentin (C1) am Institut für Veterinär-Physiologie des FB Veterinärmedizin der Freien Universität Berlin.
- 1986-1993: Wissenschaftliche Assistentin am Institut für Veterinärphysiologie der Humboldt-Universität zu Berlin.
- 2003: Privatdozentin
- 2002: Habilitation (Physiologie)
- 1996: Fachtierarzt für Physiologie
- 1989: Promotion an der Humboldt-Universität zu Berlin.
- 1984: Tierärztliche Prüfung und Erlangung des akademischen Grades Diplomveterinär-mediziner (Parasitologie)
- 1990 - 1991 postgraduales Studium der Fachrichtung Hochschulpädagogik an der Humboldt-Universität zu Berlin.
- 1979 - 1984 Studium der Veterinärmedizin an der Humboldt-Universität zu Berlin.
Publikationen
Stange, K.; Schumacher, T.; Miersch, C.; Whelan, R.; Klünemann, M.; Röntgen, M. (2023):
Methionine Sources Differently Affect Production of Reactive Oxygen Species, Mitochondrial Bioenergetics, and Growth of Murine and Quail Myoblasts In Vitro. CURR ISSUES MOL BIOL
45 (4): 2661-2680
https://doi.org/10.3390/cimb45040174
Petkov, S.; Brenmoehl, J.; Langhammer, M.; Höflich, A.; Röntgen, M. (2022):
Myogenic Precursor Cells Show Faster Activation and Enhanced Differentiation in a Male Mouse Model Selected for Advanced Endurance Exercise Performance. Cells-Basel 11 (6): 101, 1-20
https://doi.org/10.3390/cells11061001
Stange, K.; Keric, A.; Friese, A.; Röntgen, M. (2022):
Preparation of spheroids from primary pig cells in a mid-scale bioreactor retaining their myogenic potential. Cells-Basel 11 (9): 1453, 1-18
https://doi.org/10.3390/cells11091453
Schumacher, T.; Röntgen, M.; Maak, S. (2021):
Congenital Splay Leg Syndrome in Piglets - Current Knowledge and a New Approach to Etiology
. Front Vet Sci 8: 609833, 1-11
https://doi.org/10.3389/fvets.2021.609883
Tartarkova, Z.; de Baaij, H. F.; Grendar, M.; Aschenbach, J. R.; Racay, P.; Bos, C.; Sponder, G.; Hoenderop, J. G. J.; Röntgen, M.; Turcanova Koprusakova, M.; Kolisek, M. (2020):
Dietary Mg2+ Intake and the Na+/Mg2+ Exchanger SLC41A1 Influence Components of Mitochondrial Energetics in Murine Cardiomyocytes. Int J Mol Sci 21: 8221, 1-25
https://doi.org/10.3390/ijms21218221
Stange, K.; Ahrens, H. E.; von Maltzahn, J.; Röntgen, M. (2020):
Isolation and ex vivo cultivation of single myofibers from porcine muscle. IN VITRO CELL DEV-AN 56 (8): 585-592
https://doi.org/10.1007/s11626-020-00492-z
Meese, S.; Ulbrich, S. E.; Bollwein, H.; Bruckmaier, R. M.; Wellnitz, O.; Kreuzer, M.; Röntgen, M.; Gimsa, U.; Schwarm, A. (2020):
Methane emission, metabolism, and performance of Holstein dairy cows with low, medium, and high lymphocyte proliferation during transition. J Dairy Sci 103 (5): 4367-4377
https://doi.org/10.3168/jds.2019-17584
Stange, K.; Miersch, C.; Sponder, G.; Röntgen, M. (2020):
Low birth weight influences the postnatal abundance and characteristics of satellite cell subpopulations in pigs. Sci Rep-UK 10: 6149, 1-14
https://doi.org/10.1038/s41598-020-62779-1
Erdmann, S.; Derno, M.; Schäff, C. T.; Börner, S.; Kautzsch, U.; Kuhla, B.; Hammon, H. M.; Tuchscherer, A.; Röntgen, M. (2019):
Comparative analyses of estimated and calorimetrically determined energy balance in high-yielding dairy cows. J Dairy Sci 102 (5): 4002-4013
https://doi.org/10.3168/jds.2018-15017
Zitnan, R.; Albrecht, E.; Kalbe, C.; Miersch, C.; Revajova, V.; Levkut, M.; Röntgen, M. (2019):
Muscle characteristics in chicks challenged with Salmonella Enteritidis and the effect of preventive application of the probiotic Enterococcus faecium. Poultry Sci 98 (5): 2014-2025
https://doi.org/10.3382/ps/pey561
Revajova, V.; Herich, R; Levkut, M.; Zitnan, R.; Albrecht, E.; Röntgen, M.; Levkutova, M.; Karaffova, V.; Sevcikova, Z.; Paulovicova, E.; Levkut, M. (2018):
Immunolocalization of Na+/K+-ATPase and proliferative activity of enterocytes after administration of glucan in chickens fed T-2 toxin. Acta Vet Brno 87 (4): 371-377
https://doi.org/10.2754/avb201887040000
Wang, S.; Meese, S.; Ulbrich, S. E.; Bollwein, H.; Röntgen, M.; Gimsa, U.; Schwarm, A. (2018):
Effect of immune modulators on in vitro activation and proliferation of peripheral blood mononuclear cells from multiparous Holstein cows peripartum. J Anim Physiol An N 102 (6): 1515-1520
https://doi.org/10.1111/jpn.12972
Miersch, C.; Stange, K.; Röntgen, M. (2018):
Effects of trypsinization and of a combined trypsin, collagenase, and DNase digestion on liberation and in vitro function of satellite cells isolated from juvenile porcine muscles. IN VITRO CELL DEV-AN 54 (6): 406-412
https://doi.org/10.1007/s11626-018-0263-5
Miersch, C.; Stange, K.; Röntgen, M. (2018):
Separation of functionally divergent muscle precursor cell populations from porcine juvenile muscles by discontinuous Percoll density gradient centrifugation. BMC Cell Biol 19: 2, 1-12
https://doi.org/10.1186/s12860-018-0156-1
Meese, S.; Gimsa, U.; Röntgen, M.; Weitzel, J. M.; Tuchscherer, A.; Miersch, C.; Vernunft, A.; Viergutz, T.; Kreuzer, M.; Schwarm, A. (2018):
Effect of immune modulators and lactation number on in vitro proliferation of lymphocytes from non-pregnant dairy heifers and cows. Can J Anim Sci 98 (4): 898-901
https://doi.org/10.1139/CJAS-2017-0143
Sponder, G.; Abdulhanan, N.; Fröhlich, N.; Mastrototaro, L.; Aschenbach, J. R.; Röntgen, M.; Pilchova, I.; Cibulka, M.; Racay, P.; Kolisek, M. (2018):
Overexpression of Na+/Mg2+ exchanger SLC41A1 attenuates pro-survival signaling. Oncotarget 9 (4): 5084-5104
https://doi.org/10.18632/oncotarget.23598
Erdmann, S.; Mohr, E.; Derno, M.; Tuchscherer, A.; Schäff, C. T.; Börner, S.; Kautzsch, U.; Kuhla, B.; Hammon, H. M.; Röntgen, M. (2018):
Indices of heart rate variability as potential early markers of metabolic stress and compromised regulatory capacity in dried-off high-yielding dairy cows. Animal 12 (7): 1451-1461
https://doi.org/10.1017/S1751731117002725
Aguinaga Casañas, M.; Schäff, C. T.; Albrecht, E.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Nürnberg, G.; Mielenz, M. (2017):
Short communication: Free fatty acid receptors FFAR1 and FFAR2 during the peripartal period in liver of dairy cows grouped by their postpartum plasma beta-hydroxybutyrate concentrations. J Dairy Sci 100 (4): 3287-3292
https://dx.doi.org/10.3168/jds.2016-11021
Miersch, C.; Stange, K.; Hering, S.; Kolisek, M.; Viergutz, T.; Röntgen, M. (2017):
Molecular and functional heterogeneity of early postnatal porcine satellite cell populations is associated with bioenergetic profile. Sci Rep-UK 7: 45052, 1-14
https://dx.doi.org//10.1038/srep45052