Dr. agr. Martina Langhammer

+49 38208 68-902
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Genetik und Biometrie
Servicegruppe Modelltierlaboratorium
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Publikationen

Michaelis, M.; Sobczak, A.; Koczan, D.; Langhammer, M.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2018):
Testicular transcriptional signatures associated with high fertility. Reproduction 155 (2): 219-231
https://doi.org/10.1530/REP-17-0392
Michaelis, M.; Sobczak, A.; Koczan, D.; Langhammer, M.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2017):
Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile. BMC Genomics 18 (1): 889, 1-19
https://doi.org/10.1186/s12864-017-4288-z
Chen, S.; Palma Vera, S. E.; Langhammer, M.; Galuska, S. P.; Braun, B.C.; Krause, E.; Lucas-Hahn, A.; Schön, J. (2017):
An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Sci Rep-UK 7: 42298, 1-7
https://dx.doi.org/10.1038/srep42298
Langhammer, M.; Michaelis, M.; Hartmann, F.; Wudy, A.; Sobczak, A.; Nürnberg, G.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2017):
Reproductive performance primarily depends on the female genotype in a two-factorial breeding experiment using high-fertility mouse lines. Reproduction 153 (3): 361-368
https://dx.doi.org/10.1530/REP-16-0434
Hoeflich, A.; Reyer, A.; Ohde, D.; Brenmoehl, J.; Spitschak, M.; Langhammer, M.; Tuchscherer, A.; Wirthgen, E.; Renner-Müller, Ingrid; Wanke, R.; Metzger, F.; Bielohuby, M.; Wolf, E. (2016):
Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice. Aging Cell 15 (1): 111-117
https://dx.doi.org/10.1111/acel.12413
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Metges, C. C. (2016):
Maternal high-protein diet during pregnancy, but not during suckling, induced altered expression of an increasing number of hepatic genes in adult mouse offspring. Eur J Nutr 55 (3): 917-930
https://dx.doi.org/10.1007/s00394-015-0906-1
Brenmoehl, J.; Albrecht, E.; Komolka, K.; Schering, L.; Langhammer, M.; Hoeflich, A.; Maak, S. (2014):
Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise. Int J Biol Sci 10 (3): 338-349
https://dx.doi.org/10.7150/ijbs.7972
Langhammer, M.; Michaelis, M.; Hoeflich, A.; Sobczak, A.; Schön, J.; Weitzel, J. M. (2014):
High fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility. Reproduction 147 (4): 427-433
https://dx.doi.org/10.1530/REP-13-0425
Langhammer, M.; Henning, M. (2013):
Genetische Ressourcen im Nutztierbereich. In: Forschungsbericht Agrobiodiversität (Senat der Bundesforschungsistitute im BMELV, Hrsg.): 38-52
Renne, U.; Langhammer, M.; Brenmoehl, J.; Walz, C.; Zeissler, A.; Tuchscherer, A.; Piechotta, M.; Wiesner, R. J.; Bielohuby, M.; Hoeflich, A. (2013):
Lifelong obesity in a polygenic mouse model prevents age- and diet-induced glucose intolerance - obesity is no road to late-onset diabetes in mice. Plos One 8 (11): e79788, 1-8
https://dx.doi.org/10.1371/journal.pone.0079788
Michaelis, M.; Langhammer, M.; Hoeflich, A.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2013):
Initial characterization of an outbreed mouse model for male factor (in)fertility. Andrology 1 (5): 772-778
https://dx.doi.org/10.1111/j.2047-2927.2013.00108.x
Dannenberger, D.; Nürnberg, G.; Renne, U.; Nürnberg, K.; Langhammer, M.; Huber, K.; Breier, B. H. (2013):
High-fat diets rich in [omega]-3 or [omega]-6 polyunsaturated fatty acids have distinct effects on lipid profiles and lipid peroxidation in mice selected for either high body weight or leanness. Nutrition 29 (5): 765-771
https://dx.doi.org/10.1016/j.nut.2012.10.010
Rehfeldt, C.; Langhammer, M.; Kucia, M.; Nürnberg, G.; Metges, C. C. (2013):
Enhanced sensitivity of skeletal muscle growth in offspring of mice long-term selected for high body mass in response to a maternal high-protein/low-carbohydrate diet during lactation. Eur J Nutr 52 (3): 1201-1213
https://dx.doi.org/10.1007/s00394-012-0431-4
Derno, M.; Langhammer, M.; Renne, U.; Hennig, U.; Kuhla, S.; Nürnberg, G.; Klaus, S.; Brockmann, G. A.; Metges, C. C. (2012):
Mice long-term selected for high body mass are more susceptible to body fat deposition in response to a high fat diet due to insufficient increase in heat production. Arch Tierzucht 55 (6): 633-646
Sawitzky, M.; Zeissler, A.; Langhammer, M.; Bielohuby, M.; Stock, K. F.; Hammon, H. M.; Görs, S.; Metges, C. C.; Stoehr, B. J. M.; Bidlingmaier, M.; Fromm-Dornieden, C.; Baumgartner, B. G.; Christ, B.; Brenig, B.; Binder, G.; Metzger, F.; Renne, U.; Hoeflich, A. (2012):
Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. Plos One 7 (6): 1-13
https://dx.doi.org/10.1371/journal.pone.0039711
Sawitzky, M.; Stock, K. F.; Langhammer, M.; Renne, U.; Hoeflich, A. (2011):
Phosphatase und Tensin Homolog (PTEN) als neuer Biomarkerkandidat für postnatalen Muskelansatz in der Maus. Schriftenreihe / Leibniz-Institut für Nutztierbiol 18: 47-50
Nürnberg, K.; Breier, B. H.; Jayasinghe, S. N.; Bergmann, H.; Thompson, N.; Nürnberg, G.; Dannenberger, D.; Schneider, F.; Renne, U.; Langhammer, M.; Huber, K. (2011):
Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes. Nutr Metab 8: 56-69
https://dx.doi.org/10.1186/1743-7075-8-56
Renne, U.; Sawitzky, M.; Brenmoehl, J.; Bidlingmaier, M.; Bielohuby, M.; Langhammer, M.; Hoeflich, A. (2011):
Funktionale Genomanalyse in Inzuchtlinien und Auszuchtpopulationen: Interaktion von Wachstum und Lebensdauer. In: Biometrische Aspekte der Genomanalyse IV (Biometrie und Medizinische Informatik Greifswalder Seminarberichte , 19) (C. Hemmelmann ..., Hrsg.) Shaker Verlag, Aachen (978-3-8440-0155-6): 99-112
Walther, T.; Dietrich, G.; Langhammer, M.; Kucia, M.; Hammon, H. M.; Renne, U.; Siems, W.- E.; Metges, C. C. (2011):
High-protein diet in lactation leads to a sudden infant-death-like syndrome in mice. Plos One 6 (3): 1-6
https://dx.doi.org/10.1371/journal.pone.0017443
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Rehfeldt, C.; Metges, C. C. (2011):
Hepatic expression of the GH/JAK/STAT/IGF pathway, acute-phase response signalling and complement system are affected in mouse offspring by prenatal and early postnatal exposure to maternal high-protein diet. Eur J Nutr 50 (8): 611-623
https://dx.doi.org/10.1007/s00394-011-0168-5