Dr. rer. nat. Marten Michaelis

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Reproduktionsbiochemie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Männliche Fertilität
  • Endokrinologie
  • Selenoproteine

Lebenslauf

  • aktuell: Post Doc am Leibniz-Institute für Nutztierbiologie (FBN) Dummerstorf, Institute für Reproduktionsbiologie
  • Promotion in Molekularbiologie an der Humboldt Universität, Berlin
  • M.Sc. Medizinalchemie, University of Sussex, UK
  • Dipl.Ing. (FH) in Chemie an der Fachhochschule für Technik und Wirtschaft, Berlin

Publikationen

Fürbaß, R.; Michaelis, M.; Schuler, G. (2023):
Unhatched bovine blastocysts express all transcripts of the estrogen biosynthetic pathway, but steroid hormone synthesis could not yet be demonstrated. DOMEST ANIM ENDOCRIN 82: 106770, 1-9
Baddela, V. S.; Michaelis, M.; Tao, X.; Koczan, D.; Vanselow, J. (2023):
ERK1/2-SOX9/FOXL2 axis regulates ovarian steroidogenesis and favors the follicular-luteal transition. LIFE SCI ALLIANCE 6 (10): e202302100, 1-13
Calanni Pileri, M.; Michaelis, M.; Langhammer, M.; Rosellini Tognetti, P.; Weitzel, J. M. (2023):
The Imitation of the Ovarian Fatty Acid Profile of Superfertile Dummerstorf Mouse Lines during IVM of Control Line Oocytes Could Influence Their Maturation Rates. Biomedicines 11 (5): 1439, 1-13
Ludwig, C.; Bohleber, S.; Lapp, R.; Rebl, A.; Wirth, C.; Langhammer, M.; Schweizer, U.; Weitzel, J. M.; Michaelis, M. (2023):
Alterations in gonadotropin, apoptotic and metabolic pathways in granulosa cells warrant superior fertility of the Dummerstorf high fertility mouse line 1. J OVARIAN RES 16: 32, 1-16
Baddela, V. S.; Michaelis, M.; Sharma, A.; Plinski, C.; Viergutz, T.; Vanselow, J. (2022):
Estradiol production of granulosa cells is unaffected by the physiological mix of non-esterified fatty acids in follicular fluid. J Biol Chem 298 (10): 102477, 1-11
Calanni Pileri, M.; Weitzel, J. M.; Dannenberger, D.; Langhammer, M.; Michaelis, M. (2022):
Lower Plasmatic Levels of Saturated Fatty Acids and a Characteristic Fatty Acid Composition in the Ovary Could Contribute to the High-Fertility Phenotype in Dummerstorf Superfertile Mice. Int J Mol Sci 23 (18): 10245, 1-23
Calanni Pileri, M.; Weitzel, J. M.; Langhammer, M.; Michaelis, M. (2022):
Higher quality rather than superior quantity of oocytes determine the amount of fertilizable oocytes in two outbred Dummerstorf high-fertility mouse lines. Reprod Domest Anim 57 (10): 1198-1207
Ludwig, C.; Bohleber, S.; Rebl, A.; Wirth, E.; Venuto, M. T.; Langhammer, M.; Schweizer, U.; Weitzel, J. M.; Michaelis, M. (2022):
Endocrine and molecular factors of increased female reproductive performance in the Dummerstorf high-fertility mouse line FL1. J Mol Endocrinol 69 (1): 285-298
https://doi.org/10.1530/JME-22-0012
Calanni Pileri, M.; Weitzel, J. M.; Langhammer, M.; Wytrwat, E.; Michaelis, M. (2022):
Altered insulin, leptin and ghrelin hormone levels and atypical estrous cycle lengths in two highly fertile mouse lines. Reprod Domest Anim 57 (6): 577-586
https://onlinelibrary.wiley.com/doi/10.1111/rda.14097
Langhammer, M.; Wytrwat, E.; Michaelis, M.; Schön, J.; Tuchscherer, A.; Reinsch, N.; Weitzel, J. M. (2021):
Two mouse lines selected for large litter size display different lifetime fecundities. Reproduction 161: 721-730
https://doi.org/10.1530/REP-20-0563
Michaelis, M.; Sobczak, A.; Ludwig, C.; Marvanova, H.; Langhammer, M.; Schön, J.; Weitzel, J. M. (2020):
Altered testicular cell type composition in males of two outbred mouse lines selected for high fertility. Andrology 8 (5): 1419-1427
https://doi.org/10.1111/andr.12802
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
https://doi.org/10.1038/s41598-020-60935-1
Michaelis, M.; Sobczak, A.; Koczan, D.; Langhammer, M.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2018):
Testicular transcriptional signatures associated with high fertility. Reproduction 155 (2): 219-231
https://doi.org/10.1530/REP-17-0392
Michaelis, M.; Sobczak, A.; Koczan, D.; Langhammer, M.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2017):
Selection for female traits of high fertility affects male reproductive performance and alters the testicular transcriptional profile. BMC Genomics 18 (1): 889, 1-19
https://doi.org/10.1186/s12864-017-4288-z
Langhammer, M.; Michaelis, M.; Hartmann, F.; Wudy, A.; Sobczak, A.; Nürnberg, G.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2017):
Reproductive performance primarily depends on the female genotype in a two-factorial breeding experiment using high-fertility mouse lines. Reproduction 153 (3): 361-368
https://dx.doi.org/10.1530/REP-16-0434
Michaelis, M.; Sobczak, A.; Weitzel, J. M. (2014):
In vivo microinjection and electroporation of mouse testis. J Visualized Experiments 23 (90): 1-8
https://dx.doi.org/10.3791/51802
Michaelis, M.; Gralla, O.; Behrends, T.; Scharpf, M.; Endermann, T.; Rijntjes, E.; Pietschmann, N.; Hollenbach, B.; Schomburg, L. (2014):
Selenoprotein P in seminal fluid is a novel biomarker of sperm quality. Biochem Bioph Res Co 443 (3): 905-910
https://dx.doi.org/10.1016/j.bbrc.2013.12.067
Langhammer, M.; Michaelis, M.; Hoeflich, A.; Sobczak, A.; Schön, J.; Weitzel, J. M. (2014):
High fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility. Reproduction 147 (4): 427-433
https://dx.doi.org/10.1530/REP-13-0425
Michaelis, M.; Langhammer, M.; Hoeflich, A.; Reinsch, N.; Schön, J.; Weitzel, J. M. (2013):
Initial characterization of an outbreed mouse model for male factor (in)fertility. Andrology 1 (5): 772-778
https://dx.doi.org/10.1111/j.2047-2927.2013.00108.x
Hofmann, P. J.; Michaelis, M.; Götz, F.; Bartel, C.; Kienitz, T.; Quinkler, M. (2012):
Flutamide increases aldosterone levels in gonadectomized male but not female Wistar rats. Am J Hypertens 25 (6): 697-703
https://dx.doi.org/10.1038/Ajh.2012.21