PD Dr. rer. nat. habil. Manfred Mielenz

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Ernährungsphysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

ResearchGate

Forschungsinteressen

Insekten als Nutztiere zur Verwertung von Rest- und Nebenstoffen
Nährstoff-Sensing
Energieverwertung
Metabolismus
Adipokine
Fettsäuren
metabolische Signalwege
bioaktive Futterinhaltsstoffe

Lebenslauf

2013–heute: Wissenschaftlicher Mitarbeiter am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf, Institut für Ernährungsphysiologie "Oskar Kellner"
2013–heute: Privatdozent an der Rheinischen Friedrich-Wilhelms-Universität Bonn
2013: Habilitation im Fach Physiologie an der Rheinischen Friedrich-Wilhelms-Universität Bonn
2002–2012: Arbeitsgruppenleiter an der Rheinischen Friedrich-Wilhelms-Universität Bonn im Institut für Tierwissenschaften, Abteilung Physiologie und Hygiene
Promotion an der Gottfried Wilhelm Leibniz Universität Hannover; Anfertigung der Dissertation am Friedrich-Loeffler Institut, Institut Nutztiergenetik, Abteilung Funktionelle Genetik und Bioregulation, ehemals Bundesforschungsanstalt für Landwirtschaft (FAL) in Mariensee
Studium der Biologie an der Gottfried Wilhelm Leibniz Universität Hannover; Diplomarbeit an der Bundesforschungsanstalt für Landwirtschaft (FAL) in Mariensee

Lehre

Physiologie und Anatomie

Publikationen

Liermann, W.; Vogel, L.; Gnott, M.; Dannenberger, D.; Reyer, H.; Trakooljul, N.; Mielenz, M.; Starke, A.; Tröscher, A.; Hammon, H. M. (2026):

Influences of an abomasal fatty acid supplementation during late gestation and early lactation on the jejunal fatty acid composition, barrier function and adherent microbiota in dairy cows

Wendy Liermann, Dirk Dannenberger, Henry Reyer, Manfred Mielenz, Harald Michael Hammon

Journal of Dairy Science 109 (5): 5216-5230

https://doi.org/10.3168/jds.2025-27870

Mielenz, M.; Geick, T.; Görs, S.; Daş, G.; Dannenberger, D.; Gasco, L.; Oddon, S. B.; Deruytter, D.; Hüther, L.; Dänicke, S.; Metges, C. C. (2025):

Energy and nutrient composition and origin of common feed substrates for black soldier fly larvae determine their efficiency and life-stage-specific carbon dioxide and ammonia production

Manfred Mielenz, Solvig Görs, Gürbüz Daş, Dirk Dannenberger, Cornelia Christiane Metges

Bioresource Technology 443: 133812, 1-11

https://doi.org/10.1016/j.biortech.2025.133812

Reyer, H.; Mielenz, M.; Daş, G.; Metges, C. C.; Wimmers, K. (2025):

Microbial profiling of black soldier fly larvae reared on substrates supplemented with different mineral sources originating from phosphorus recycling technologies

Henry Reyer, Manfred Mielenz, Gürbüz Daş, Cornelia Christiane Metges, Klaus Wimmers

Animal Microbiome 7: 14, 1-14

https://doi.org/10.1186/s42523-025-00380-5

Seyedalmoosavi, M. M.; Daş, G.; Mielenz, M.; Maak; S.; Wolf, P.; Metges, C. C. (2024):

Growth, nutrient uptake, blood metabolites and bone properties in broilers consuming feed with mineral-enriched whole black soldier fly larvae

Gürbüz Daş, Manfred Mielenz, Steffen Maak, Cornelia Christiane Metges

Journal of Insects as Food and Feed 10: 2071–2083

https://doi.org/10.1163/23524588-00001208

Deruytter, D.; Gasco, L.; Yakti, W.; Katz, H.; Coudron, C. L.; Gligorescu, A.; Frooninckx, L.; Noyens, I.; Meneguz, M.; Grosso, F.; Bellezza Oddon, S.; Biasato, I.; Mielenz, M.; Veldkamp, T.; van Loon, J. J. A.; Spranghers, T.; Vandenberg, G. W.; Oonincx, D. G. A. B.; Bosch, G. (2023):

Standardising black soldier fly larvae feeding experiments: an initial protocol and variability estimates

Manfred Mielenz

Journal of Insects as Food and Feed 10: 1685–1696

https://doi.org/10.1163/23524588-20230008

Seyedalmossavi, S. M.; Mielenz, M.; Schleifer, K.; Görs, S.; Wolf, P.; Tränckner, J.; Hüther, L.; Dänicke, S.; Daş, G.; Metges, C. C. (2023):

Upcycling of recycled minerals from sewage sludge through black soldier fly larvae (Hermetia illucens): Impact on growth and mineral accumulation

Manfred Mielenz, Solvig Görs, Gürbüz Daş, Cornelia Christiane Metges

Journal of Environmental Management 344: 118695, 1-12

https://doi.org/10.1016/j.jenvman.2023.118695

Daş, G.; Seyedalmossavi, S. M.; Schleifer, K.; Mielenz, M.; Metges, C. C. (2023):

The validity of the bioaccumulation index versus the bioaccumulation factor for assessment of element accumulation in black soldier fly larvae

Gürbüz Daş, Manfred Mielenz, Cornelia Christiane Metges

Journal of Insects as Food and Feed 9 (10): 1365-1379

https://doi.org/10.3920/JIFF2023.0021

Veshkini, A.; Gnott, M.; Vogel, L.; Kröger-Koch, C.; Tuchscherer, A.; Tröscher, A.; Bernabucci, U.; Trevesi, E.; Starke, A.; Mielenz, M.; Bachmann, L.; Hammon, H. M. (2023):

Abomasal infusion of essential fatty acids and conjugated linoleic acid during late pregnancy and early lactation affects immunohematological and oxidative stress markers in dairy cows

Manfred Mielenz, Lisa Bachmann, Harald Michael Hammon

Journal of Dairy Science 106 (7): 5096-5114

https://doi.org/10.3168/jds.2022-22514

Seyedalmossavi, S. M.; Dannenberger, D.; Pfuhl, R.; Görs, S.; Mielenz, M.; Maak, S.; Wolf, P.; Daş, G.; Metges, C. C. (2023):

Lipid metabolism, fatty acid composition and meat quality in broilers supplemented with increasing levels of defrosted black soldier fly larvae

Dirk Dannenberger, Solvig Görs, Manfred Mielenz, Steffen Maak, Gürbüz Daş, Cornelia Christiane Metges

Journal of Insects as Food and Feed 9 (5): 583-598

https://doi.org/10.3920/JIFF2022.0125

Seyedalmossavi, S. M.; Mielenz, M.; Veldkamp, T.; Das, G.; Metges, C. C. (2022):

Growth efficiency, intestinal biology, and nutrient utilization and requirements of black soldier fly (Hermetia illucens) larvae compared to monogastric livestock species: a review

Manfred Mielenz, Gürbüz Daş, Cornelia Christiane Metges

Journal of Animal Science and Biotechnology 13: 31, 1-20

https://doi.org/10.1186/s40104-022-00682-7

Seyedalmossavi, S. M.; Mielenz, M.; Görs, S.; Wolf, P.; Das, G.; Metges, C. C. (2022):

Effects of increasing levels of whole Black Soldier Fly (Hermetia illucens) larvae in broiler rations on acceptance, nutrient and energy intakes and utilization, and growth performance of broilers

Manfred Mielenz, Solvig Görs, Gürbüz Daş, Cornelia Christiane Metges

Poultry Science 101 (12): 102202, 1-15

https://doi.org/10.1016/j.psj.2022.102202

Revskij, D.; Haubold, S. S.; Plinski, C.; Viergutz, T.; Tuchscherer, A.; Kröger-Koch, C.; Albrecht, E.; Günther, J.; Tröscher, A.; Hammon, H. M.; Schuberth, H.-J.; Mielenz, M. (2022):

Cellular detection of the chemokine receptor CXCR4 in bovine mammary glands and its distribution and regulation on bovine leukocytes

Elke Albrecht, Juliane Günther, Harald Michael Hammon, Manfred Mielenz

Journal of Dairy Science 105 (1): 866-876

https://doi.org/10.3168/jds.2021-20799

Koch, F.; Derno, M.; Langhammer, M.; Tuchscherer, A.; Hammon, H. M.; Mielenz, M.; Metges, C. C.; Kuhla, B. (2021):

A high-protein diet containing inulin/oligofructose supports body weight gain associated with lower energy expenditure and carbohydrate oxidation, and alters faecal microbiota in C57BL/6 mice. J NUTR SCI 10: e50, 1-10

Franziska Koch, Harald Michael Hammon, Manfred Mielenz, Cornelia Christiane Metges, Björn Kuhla

https://doi.org/10.1017/jns.2021.42

Gnott, M.; Vogel, L.; Kröger-Koch, C.; Dannenberger, D.; Tuchscherer, A.; Tröscher, A.; Trevisi, E.; Stefaniak, T.; Jawor, P.; Starke, S.; Mielenz, M.; Bachmann, L.; Hammon, H. M. (2020):

Changes in fatty acids in plasma and association with the inflammatory response in dairy cows abomasally infused with essential fatty acids and conjugated linoleic acid during late and early lactation. J Dairy Sci 103 (12): 11889-11910

Dirk Dannenberger, Manfred Mielenz, Lisa Bachmann, Harald Michael Hammon

https://doi.org/10.3168/jds.2020-18735

Revskij, D.; Haubold, S. S.; Viergutz, T.; Kröger-Koch, C.; Tuchscherer, A.; Kirchberger, H.S.; Rychlik, M.; Tröscher, A.; Hammon, H. M.; Schuberth, H.-J.; Mielenz, M. (2019):

Dietary fatty acids affect red blood cell membrane composition and red blood cell ATP release in dairy cows. Int J Mol Sci 20: 2769, 1-19

Harald Michael Hammon, Manfred Mielenz

https://doi.org/10.3390/ijms20112769

Mansouryar, M.; Mirzaei-Alamouti, H.; Dehghan-banadaky, M.; Sauerwein, H.; Mielenz, M.; Nielsen, M. O. (2018):

Short communication: relationship between body condition score and plasma adipokines in early-lactating Holstein dairy cows. J Dairy Sci 101 (9): 8552-8558

Manfred Mielenz

https://doi.org/10.3168/jds.2017-14122

Mielenz, M.; Pfaffl, M.W.; Schlumbohm, C.; Harmeyer, J.; Parvizi, N. (2018):

Growth hormone secretion patterns in German Landrace (DL) fetuses and piglets compared to DL piglets with inherited 1,25-dihydroxyvitamin D3 deficiency. Nutrients 10: 617, 1-7

Manfred Mielenz

Sadri, H.; Saremi, B.; Dänicke, S.; Rehage, J.; Mielenz, M.; Sauerwein, H. (2018):

Lactation-related changes in tissue expression of PEDF in dairy cows. DOMEST ANIM ENDOCRIN 64: 93-101

Manfred Mielenz

https://doi.org/10.1016/j.domaniend.2018.04.004

Aguinaga Casañas, M.; Schäff, C. T.; Albrecht, E.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Nürnberg, G.; Mielenz, M. (2017):

Short communication: Free fatty acid receptors FFAR1 and FFAR2 during the peripartal period in liver of dairy cows grouped by their postpartum plasma beta-hydroxybutyrate concentrations. J Dairy Sci 100 (4): 3287-3292

Elke Albrecht, Harald Michael Hammon, Björn Kuhla, Monika Röntgen, Manfred Mielenz

https://dx.doi.org/10.3168/jds.2016-11021

Mielenz, M. (2017):

Invited review: nutrient-sensing receptors for free fatty acids and hydroxycarboxylic acids in farm animals. Animal 11 (6): 1008-1016

Manfred Mielenz

https://dx.doi.org/10.1017/S175173111600238X