PD Dr. rer. nat. habil. Manfred Mielenz

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Ernährungsphysiologie
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Insekten als Nutztiere zur Verwertung von Rest- und Nebenstoffen
  • Nährstoff-Sensing
  • Energieverwertung
  • Metabolismus
  • Adipokine
  • Fettsäuren
  • metabolische Signalwege
  • bioaktive Futterinhaltsstoffe

Lebenslauf

  • 2013–heute: Wissenschaftlicher Mitarbeiter am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf, Institut für Ernährungsphysiologie "Oskar Kellner"
  • 2013–heute: Privatdozent an der Rheinischen Friedrich-Wilhelms-Universität Bonn
  • 2013: Habilitation im Fach Physiologie an der Rheinischen Friedrich-Wilhelms-Universität Bonn
  • 2002–2012: Arbeitsgruppenleiter an der Rheinischen Friedrich-Wilhelms-Universität Bonn im Institut für Tierwissenschaften, Abteilung Physiologie und Hygiene
  • Promotion an der Gottfried Wilhelm Leibniz Universität Hannover; Anfertigung der Dissertation am Friedrich-Loeffler Institut, Institut Nutztiergenetik, Abteilung Funktionelle Genetik und Bioregulation, ehemals Bundesforschungsanstalt für Landwirtschaft (FAL) in Mariensee
  • Studium der Biologie an der Gottfried Wilhelm Leibniz Universität Hannover; Diplomarbeit an der Bundesforschungsanstalt für Landwirtschaft (FAL) in Mariensee

Lehre

  • Physiologie und Anatomie

Publikationen

Deruytter, D.; Gasco, L.; Yakti, W.; Katz, H.; Coudron, C. L.; Gligorescu, A.; Frooninckx, L.; Noyens, I.; Meneguz, M.; Grosso, F.; Bellezza Oddon, S.; Biasato, I.; Mielenz, M.; Veldkamp, T.; van Loon, J. J. A.; Spranghers, T.; Vandenberg, G. W.; Oonincx, D. G. A. B.; Bosch, G. (2023):
Standardising black soldier fly larvae feeding experiments: an initial protocol and variability estimates [epublished ahead of print].
J Insects Food Feed
https://doi.org/10.1163/23524588-20230008
Seyedalmossavi, S. M.; Mielenz, M.; Schleifer, K.; Görs, S.; Wolf, P.; Tränckner, J.; Hüther, L.; Dänicke, S.; Daş, G.; Metges, C. C. (2023):
Upcycling of recycled minerals from sewage sludge through black soldier fly larvae (Hermetia illucens): Impact on growth and mineral accumulation. J ENVIRON MANAGE 344: 118695, 1-12
Daş, G.; Seyedalmossavi, S. M.; Schleifer, K.; Mielenz, M.; Metges, C. C. (2023):
The validity of the bioaccumulation index versus the bioaccumulation factor for assessment of element accumulation in black soldier fly larvae [epublished ahead of print]. J INSECTS FOOD FEED
Veshkini, A.; Gnott, M.; Vogel, L.; Kröger-Koch, C.; Tuchscherer, A.; Tröscher, A.; Bernabucci, U.; Trevesi, E.; Starke, A.; Mielenz, M.; Bachmann, L.; Hammon, H. M. (2023):
Abomasal infusion of essential fatty acids and conjugated linoleic acid during late pregnancy and early lactation affects immunohematological and oxidative stress markers in dairy cows [epublished ahead of print]. J Dairy Sci
Seyedalmossavi, S. M.; Dannenberger, D.; Pfuhl, R.; Görs, S.; Mielenz, M.; Maak, S.; Wolf, P.; Daş, G.; Metges, C. C. (2023):
Lipid metabolism, fatty acid composition and meat quality in broilers supplemented with increasing levels of defrosted black soldier fly larvae . J INSECTS FOOD FEED 9 (5): 583-598
Seyedalmossavi, S. M.; Mielenz, M.; Veldkamp, T.; Das, G.; Metges, C. C. (2022):
Growth efficiency, intestinal biology, and nutrient utilization and requirements of black soldier fly (Hermetia illucens) larvae compared to monogastric livestock species: a review. J Anim Sci Biotechno 13: 31, 1-20
Seyedalmossavi, S. M.; Mielenz, M.; Görs, S.; Wolf, P.; Das, G.; Metges, C. C. (2022):
Effects of increasing levels of whole Black Soldier Fly (Hermetia illucens) larvae in broiler rations on acceptance, nutrient and energy intakes and utilization, and growth performance of broilers. Poultry Sci 101 (12): 102202, 1-15
Revskij, D.; Haubold, S. S.; Plinski, C.; Viergutz, T.; Tuchscherer, A.; Kröger-Koch, C.; Albrecht, E.; Günther, J.; Tröscher, A.; Hammon, H. M.; Schuberth, H.-J.; Mielenz, M. (2022):
Cellular detection of the chemokine receptor CXCR4 in bovine mammary glands and its distribution and regulation on bovine leukocytes. J Dairy Sci 105 (1): 866-876
https://doi.org/10.3168/jds.2021-20799
Koch, F.; Derno, M.; Langhammer, M.; Tuchscherer, A.; Hammon, H. M.; Mielenz, M.; Metges, C. C.; Kuhla, B. (2021):
A high-protein diet containing inulin/oligofructose supports body weight gain associated with lower energy expenditure and carbohydrate oxidation, and alters faecal microbiota in C57BL/6 mice. J NUTR SCI 10: e50, 1-10
https://doi.org/10.1017/jns.2021.42
Gnott, M.; Vogel, L.; Kröger-Koch, C.; Dannenberger, D.; Tuchscherer, A.; Tröscher, A.; Trevisi, E.; Stefaniak, T.; Jawor, P.; Starke, S.; Mielenz, M.; Bachmann, L.; Hammon, H. M. (2020):
Changes in fatty acids in plasma and association with the inflammatory response in dairy cows abomasally infused with essential fatty acids and conjugated linoleic acid during late and early lactation. J Dairy Sci 103 (12): 11889-11910
https://doi.org/10.3168/jds.2020-18735
Revskij, D.; Haubold, S. S.; Viergutz, T.; Kröger-Koch, C.; Tuchscherer, A.; Kirchberger, H.S.; Rychlik, M.; Tröscher, A.; Hammon, H. M.; Schuberth, H.-J.; Mielenz, M. (2019):
Dietary fatty acids affect red blood cell membrane composition and red blood cell ATP release in dairy cows. Int J Mol Sci 20: 2769, 1-19
https://doi.org/10.3390/ijms20112769
Mansouryar, M.; Mirzaei-Alamouti, H.; Dehghan-banadaky, M.; Sauerwein, H.; Mielenz, M.; Nielsen, M. O. (2018):
Short communication: relationship between body condition score and plasma adipokines in early-lactating Holstein dairy cows. J Dairy Sci 101 (9): 8552-8558
https://doi.org/10.3168/jds.2017-14122
Mielenz, M.; Pfaffl, M.W.; Schlumbohm, C.; Harmeyer, J.; Parvizi, N. (2018):
Growth hormone secretion patterns in German Landrace (DL) fetuses and piglets compared to DL piglets with inherited 1,25-dihydroxyvitamin D3 deficiency. Nutrients 10: 617, 1-7
Sadri, H.; Saremi, B.; Dänicke, S.; Rehage, J.; Mielenz, M.; Sauerwein, H. (2018):
Lactation-related changes in tissue expression of PEDF in dairy cows. DOMEST ANIM ENDOCRIN 64: 93-101
https://doi.org/10.1016/j.domaniend.2018.04.004
Aguinaga Casañas, M.; Schäff, C. T.; Albrecht, E.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Nürnberg, G.; Mielenz, M. (2017):
Short communication: Free fatty acid receptors FFAR1 and FFAR2 during the peripartal period in liver of dairy cows grouped by their postpartum plasma beta-hydroxybutyrate concentrations. J Dairy Sci 100 (4): 3287-3292
https://dx.doi.org/10.3168/jds.2016-11021
Mielenz, M. (2017):
Invited review: nutrient-sensing receptors for free fatty acids and hydroxycarboxylic acids in farm animals. Animal 11 (6): 1008-1016
https://dx.doi.org/10.1017/S175173111600238X
Schäff, C. T.; Gruse, J.; Maciej, J.; Mielenz, M.; Wirthgen, E.; Hoeflich, A.; Schmicke, M.; Pfuhl, R.; Jawor, P.; Stefaniak, T.; Hammon, H. M. (2016):
Effects of feeding milk replacer ad libitum or in restricted amounts for the first five weeks of life on the growth, metabolic adaptation, and immune status of newborn calves. Plos One 11 (12): e0168974, 1-24
https://dx.doi.org/10.1371/journal.pone.0168974
van den Borne, J.J.G.C.; Labussière, E.; Mielenz, M.; Sauerwein, H.; Gerrits, W. J. J. (2016):
Exchanging fat for lactose in milk replacer stimulates de novo lipogenesis in calves. In: Energy and protein metabolism and nutrition : 5th EAAP International Symposium, Krakow, Poland, 12-15 September 2016 (EAAP Publication , 137) (Jacek Skomial, Hélène Lapierre, Hrsg.) Wageninen Academic Publishers, Wageningen (978-90-8686-286-3): 145-146
Stoldt, A.-K.; Mielenz, M.; Nürnberg, G.; Sauerwein, H.; Esatbeyoglu, T.; Wagner, A. E.; Rimbach, G.; Starke, S.; Wolffram, S.; Metges, C. C. (2016):
Effects of a six-week intraduodenal supplementation with quercetin on liver lipid metabolism and oxidative stress in peripartal dairy cows. J Anim Sci 94 (5): 1913-1923
https://dx.doi.org/10.2527/jas.2016-0338
Friedrichs, P.; Sauerwein, H.; Huber, K.; Locher, L. F.; Rehage, J.; Meyer, U.; Dänicke, S.; Kuhla, B.; Mielenz, M. (2016):
Expression of metabolic sensing receptors in adipose tissues of periparturient dairy cows with differing extent of negative energy balance. Animal 10 (4): 623-632
https://dx.doi.org/10.1017/s175173111500227x