Dr. rer. nat. Julia Brenmoehl

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Endokrinologie der Nutztiere
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Fett- und Ernergiemetabolismus, Zellsignalanalyse

Lebenslauf

  • seit 2009: Forschungsinstitut für Nutztierbiologie (FBN)
  • 2007–2009: Universitätsklinikum Jena, Innere Medizin IV, Abteilung für Gastroenterologie, Hepatologie und Infektiologie
  • 2005–2007: Promotion zum Dr. rer. nat.
  • 2003–2004: wissenschaftliche Tätigkeit im Fach Biologie, Universität Regensburg
  • 2002–2006: Universitätsklinikum Regensburg, Abteilung für Gastroenterologie, Endokrinologie, Rheumatologie, Infectiologie und Notfallmedizin
  • 2002: Universitätsklinikum Rostock, Innere Medizin, Abteilung Gastroenterologie
  • 2001–2001: Creatogen AG Augsburg, Abteilung für Impfstoffe
  • 1997–2002: Studium der Biotechnologie, Fachhochschule Jena
  • 1997: Hochschulreife

Publikationen

Brenmoehl, J.; Brosig, E.; Trakooljul, N.; Walz, C.; Ohde, D.; Noce, A.; Walz, M.; Langhammer, M.; Petkov, S.; Röntgen, M.; Maak, S.; Galuska, C. E.; Fuchs, B.; Kuhla, B.; Ponsuksili, S.; Wimmers, K.; Hoeflich, A. (2023):
Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC) - a Possible Role of Lactate Dehydrogenase in Metabolic Flexibility. Cells-Basel 12 (15): 1925, 1-21
https://doi.org/10.3390/cells12151925
Galow, A.-M.; Brenmoehl, J.; Höflich, A. (2023):
Synergistic effects of hormones on structural and functional maturation of cardiomyocytes and implications for heart regeneration. Cell Mol Life Sci 80: 240, 1-33
https://doi.org/10.1007/s00018-023-04894-6
Höflich, A.; Galow, A.-M.; Brenmoehl, J.; Hadlich, F. (2023):
Growth and development of the mammary gland in mice-control of the insulin-like growth factor system by hormones and metalloproteases, and putative interference with micro RNAs. ANIM FRONT 13 (3): 84-92
https://doi.org/10.1093/af/vfad024
Müller-Eigner, A.; Sanz-moreno, A.; de Diego, I.; Venkateswaran Venkatasubramani, A.; Langhammer, M.; Gerlini, R.; Rathkolb, B.; Aguilar-Pimentel, A.; Klein-Rodewald, T.; Calzada-Wack, J.; Becker, L.; Palma Vera, S. E.; Gille, B.; Forne, I.; Imhof, A.; Meng, C.; Ludwig, A.; Koch, F.; Heiker, J.; Kuhla, A.; Caton, V.; Brenmoehl, J.; Reyer, H.; Schön, J.; Fuchs, H.; Gailus-Durner, V.; Höflich, A.; Hrabe de Angelis, M.; Peleg, S. (2022):
Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse. COMMUN BIOL 5: 408, 1-17
https://doi.org/10.1038/s42003-022-03339-3
Petkov, S.; Brenmoehl, J.; Langhammer, M.; Höflich, A.; Röntgen, M. (2022):
Myogenic Precursor Cells Show Faster Activation and Enhanced Differentiation in a Male Mouse Model Selected for Advanced Endurance Exercise Performance. Cells-Basel 11 (6): 101, 1-20
https://doi.org/10.3390/cells11061001
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418
Walz, M.; Höflich, C.; Walz, C.; Ohde, D.; Brenmoehl, J.; Sawitzky, M.; Vernunft, A.; Zettl, U. K.; Holtze, S.; Hildebrandt, T. B.; Wolf, E.; Hoeflich, A. (2021):
Development of a Sensitive Bioassay for the Analysis of IGF-Related Activation of AKT/mTOR Signaling in Biological Matrices. Cells-Basel 10 (3): 482, 1-19
https://doi.org/10.3390/cells10030482
Walz, C.; Brenmoehl, J.; Trakooljul, N.; Noce, A.; Caffier, C.; Ohde, D.; Langhammer, M.; Wimmers, K.; Ponsuksili, S.; Hoeflich, A. (2021):
Control of Protein and Energy Metabolism in the Pituitary Gland in Response to Three-Week Running Training in Adult Male Mice . Cells-Basel 10 (4): 736, 1-20
https://doi.org/10.3390/cells10040736
Noce, A.; Qanbari, S.; Gonzalez-Prendes, R.; Brenmoehl, J.; Luigi-Sierra, M. G.; Theerkorn, M.; Fiege, M.-A.; Pilz, H.; Bota, A.; Vidu, L.; Horwath, C.; Haraszthy, L.; Penchev, P.; Ilieva, Y.; Peeva, T.; Lüpcke, W.; Krawczynski, R.; Wimmers, K.; Thiele, M.; Hoeflich, A. (2021):
Genetic Diversity of Bubalus bubalis in Germany and Global Relations of Its Genetic Background. Front Genet 11: 610353, 1-16
https://doi.org/10.3389/fgene.2020.610353
Hoeflich, A.; Fitzner, B.; Walz, C.; Hecker, M.; Tuchscherer, A.; Brenmoehl, J.; Zettl, U. K. (2021):
Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis. Front Endocrinol 11: 565557, 1-10
https://doi.org/10.3389/fendo.2020.565557
Braude, S.; Holtze, S.; Begall, S.; Brenmoehl, J.; Burda, H.; Dammann, P.; de Marmol, D.; Gorshkova, E.; Henning, Y.; Hoeflich, A.; Höhn, A.; Jung, T.; Hamo, D.; Sahm, A.; Shebzukhov, Y.; Šumbera, R.; Miwa, S.; Vyssokikh, M.; von Zglinicki, T.; Averina, O.; Hildebrandt, T. B. (2021):
Surprisingly long survival of premature conclusions about naked mole-rat biology. Biol Rev 96 (2): 376-393
https://doi.org/10.1111/brv.12660
Logotheti, S.; Marquardt, S.; Gupta, S.K.; Richter, C.; Edelhäuser, B. A. H.; Engelmann, D.; Brenmoehl, J.; Söhnchen, C.; Murr, N.; Alpers, M.; Singh, K. P.; Wolkenhauer, O.; Heckl, D.; Spitschak, A.; Pützer, B. M. (2020):
LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1. Theranostics 10 (21): 9620-9643
https://doi.org/10.7150/thno.44176
Brenmoehl, J.; Ohde, D.; Walz, C.; Langhammer, M.; Schultz, J.; Hoeflich, A. (2020):
Analysis of activity-dependent energy metabolism in mice reveals regulation of mitochondrial fission and fusion mRNA by voluntary physical exercise in subcutaneous fat from male marathon mice (DUhTP). Cells-Basel 9: 2697, 1-20
https://doi.org/10.3390/cells9122697
Walz, M.; Chau, L.; Sawitzky, M.; Ohde, D.; Brenmoehl, J.; Tuchscherer, A.; Langhammer, M.; Metzger, F.; Höflich, C.; Hoeflich, A. (2020):
Overlap of peak growth activity and peak IGF-1 to IGFBP ratio: delayed increase of IGFBPs versus IGF-1 in serum as a mechanism to speed up and down postnatal weight gain in mice. Cells-Basel 9 (6): 1516, 1-12
https://doi.org/10.3390/cells9061516
Hoeflich, A.; Fitzner, B.; Walz, C.; Hecker, M.; Tuchscherer, A.; Bastian, M.; Brenmoehl, J.; Schröder, S.; Willenberg, H.S.; Reincke, M. (2020):
Systemic effects by intrathecal administration of triamcinolone acetonide in patients with multiple sclerosis. Front Endocrinol 11: 574, 1-8
https://doi.org/10.3389/fendo.2020.00574
Ohde, D.; Walz, M.; Walz, C.; Noce, A.; Brenmoehl, J.; Langhammer, M.; Hoeflich, A. (2020):
Sex-specific control of muscle mass: elevated IGFBP proteolysis and reductions of IGF-1 levels are associated with substantial loss of carcass weight in male DU6PxIGFBP-2 transgenic mice. Cells-Basel 9 (10): 2174, 1-17
https://doi.org/10.3390/cells9102174
Verleih, M.; Borchel, A.; Rebl, A.; Brenmoehl, J.; Kühn, C.; Goldammer, T. (2019):
A molecular survey of programmed cell death in rainbow trout: Structural and functional specifications of apoptotic key molecules. Comp Biochem Phys B 230: 57-69
https://doi.org/10.1016/j.cbpb.2019.01.012
Wirthgen, E.; Otten, W.; Tuchscherer, M.; Tuchscherer, A.; Domanska, G.; Brenmoehl, J.; Günther, J.; Ohde, D.; Weitschies, W.; Seidlitz, A.; Scheuch, E.; Kanitz, E. (2018):
Effects of 1-Methyltryptophan on immune responses and the kynurenine pathway after lipopolysaccharide challenge in pigs. Int J Mol Sci 19 (10): 3009, 1-23
https://doi.org/10.3390/ijms19103009
Brenmoehl, J.; Walz, C.; Spitschak, M.; Wirthgen, E.; Walz, M.; Langhammer, M.; Tuchscherer, A.; Naumann, R.; Höflich, A. (2018):
Partial phenotype conversion and differential trait response to conditions of husbandry in mice. J Comp Physiol B 188 (3): 527-539
https://doi.org/10.1007/s00360-017-1138-x
Brenmoehl, J.; Ohde, D.; Wirthgen, E.; Hoeflich, A. (2018):
Cytokines in milk and the role of TGF-beta. Best Pract Res Cl En 32 (1): 47-56
https://doi.org/10.1016/j.beem.2018.01.006