PD Dr. rer. nat. habil. Jens Vanselow

+49 38208 68-752
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Fortpflanzungsbiologie
Institutsleitung
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Reproduktionsbiologie
  • Follikulogenese, Luteinisierung
  • Genregulation
  • Epigenetik

Lebenslauf

  • 2013-heute: Leiter des Instituts für Fortpflanzungsbiologie am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2002: Habilitation und Dozent an der Mathematisch-Naturwissenschaftlichen Fakultät und Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 1992-2012: Leiter der Abteilung Genregulation am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf, Forschungsbereich Molekularbiologie
  • 1990-1992: Postdoc-Stipendiat des Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow am Massachusetts General Hospital, Institut für Entwicklungsbiologie, Boston, USA
  • 1988-1990: Mitglied des DFG Graduierten Kollegs "Neurobiologie" an der Eberhard Karls Universität Tübingen
  • 1990: Promotion zum Dr. rer. nat. an der Eberhard Karls Universität Tübingen und am Max-Planck-Institut für Entwicklungsbiologie Tübingen
  • 1987: Diplom in Biologie an der Eberhard Karls Universität Tübingen
  • 1983: Vordiplom in Biologie an der Johannes Gutenberg University Mainz

Lehre

  • 2013-heute: "Populationsgenetik, molekulare Tierzucht und Reproduktionstechniken" (MSc) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2014-heute: "Zuchtprogramme und Reproduktionsmanagement" (B.Sc.) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2011-heute: "Molekulare Tierzucht" (MSc) an der Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock
  • 1997-2010: "Molekulare Mechanismen der Entwicklung und and Differenzierung" (Dipl.-Biol.), Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock

Publikationen

Vanselow, J.; Conley, A.J.; Corbin, C.; Berger, T (2021):
Genomic structure of the porcine CYP19 locus and expression of the CYP19A3 paralog. Genes-Basel
Yenuganti, V.; Koczan, D.; Vanselow, J. (2021):
Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition. BMC Genomics
Vanselow, J.; Conley, A.; Berger, T (2021):
Aromatase and the three little paralogs. Biol Reprod
Vanselow, J.; Christenson, L. K.; Pate, J. L. (2020):
Editorial: Regulation of dynamic changes and remodeling events during the formation, rescue and regression of the corpus luteum. Front Endocrinol 11: 244, 1-2
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
Baddela, V. S.; Sharma, A.; Vanselow, J. (2020):
Non-esterified fatty acids in the ovary: friends or foes?. Reprod Biol Endocrin 18: 60, 1-14
Pöhland, R.; Souza Cáceres, M. B.; Datta, T. K.; Vanselow, J.; Martins, M.I.M.; Silva, W.A.L.; Cardoso, C. T.; Melo Sterza, F. A. (2020):
Influence of long-term thermal stress on the in vitro maturation on embryo development and Heat Shock Protein abundance in zebu cattle. Anim Reprod 17 (3): e20190085, 1-10
Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
Sharma, A.; Baddela, V. S.; Becker, F.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
Baddela, V. S.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
Global gene expression analysis indicates that small luteal cells are involved in extracellular matrix modulation and immune cell recruitment in the bovine corpus luteum. Mol Cell Endocrinol 474: 201-213
Baufeld, A.; Vanselow, J. (2018):
Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage. Reprod Biol Endocrin 16: 15, 1-11
Baddela, V. S.; Sharma, A.; Viergutz, T.; Koczan, D.; Vanselow, J. (2018):
Low oxygen levels induce early luteinization associated changes in bovine granulosa cells. Front Physiol 9: 1066, 1-15
Baddela, V. S.; Sharma, A.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
mRNA microarraydata of FACS purified bovine small and large luteal cells. Data in brief 19: 737-742
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. 139: e58208
Baufeld, A.; Koczan, D.; Vanselow, J. (2017):
Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density. Reprod Biol Endocrin 15: 3, 1-14
Yenuganti, V.; Vanselow, J. (2017):
Cultured bovine granulosa cells rapidly lose important features of their identity and functionality but partially recover under long-term culture conditions. Cell Tissue Res 368 (2): 397-403
Yenuganti, V.; Vanselow, J. (2017):
Oleic acid induces down-regulation of the granulosa cell identity marker FOXL2, and up-regulation of the Sertoli cell marker SOX9 in bovine granulosa cells. Reprod Biol Endocrin 15: 57, 1-5
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Metges, C. C. (2016):
Maternal high-protein diet during pregnancy, but not during suckling, induced altered expression of an increasing number of hepatic genes in adult mouse offspring. Eur J Nutr 55 (3): 917-930
Yenuganti, V.; Viergutz, T.; Vanselow, J. (2016):
Oleic acid induces specific alterations in the morphology, gene expression and steroid hormone production of cultured bovine granulosa cells. Gen Comp Endocr 232: 134-144