PD Dr. rer. nat. habil. Jens Vanselow

+49 38208 68-752
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Fortpflanzungsbiologie
Institutsleitung
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Reproduktionsbiologie
  • Follikulogenese, Luteinisierung
  • Genregulation
  • Epigenetik

Lebenslauf

  • 2013-heute: Leiter des Instituts für Fortpflanzungsbiologie am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2002: Habilitation und Dozent an der Mathematisch-Naturwissenschaftlichen Fakultät und Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 1992-2012: Leiter der Abteilung Genregulation am Leibniz Institut für Nutztierbiologie (FBN) Dummerstorf, Forschungsbereich Molekularbiologie
  • 1990-1992: Postdoc-Stipendiat des Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow am Massachusetts General Hospital, Institut für Entwicklungsbiologie, Boston, USA
  • 1988-1990: Mitglied des DFG Graduierten Kollegs "Neurobiologie" an der Eberhard Karls Universität Tübingen
  • 1990: Promotion zum Dr. rer. nat. an der Eberhard Karls Universität Tübingen und am Max-Planck-Institut für Entwicklungsbiologie Tübingen
  • 1987: Diplom in Biologie an der Eberhard Karls Universität Tübingen
  • 1983: Vordiplom in Biologie an der Johannes Gutenberg University Mainz

Lehre

  • 2013-heute: "Populationsgenetik, molekulare Tierzucht und Reproduktionstechniken" (MSc) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2014-heute: "Zuchtprogramme und Reproduktionsmanagement" (B.Sc.) an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2011-heute: "Molekulare Tierzucht" (MSc) an der Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock
  • 1997-2010: "Molekulare Mechanismen der Entwicklung und and Differenzierung" (Dipl.-Biol.), Mathematisch-naturwissenschaftliche Fakultät der Universität Rostock

Publikationen

Baufeld, A.; Vanselow, J. (2022):
Lactate-induced effects on bovine granulosa cells are mediated via PKA signaling. Cell Tissue Res 388 (2): 471-477
https://doi.org/10.1007/s00441-021-03569-7
Baddela, V. S.; Sharma, A.; Plinski, C.; Vanselow, J. (2022):
Palmitic acid protects granulosa cells from oleic acid induced steatosis and rescues progesterone production via cAMP dependent mechanism. BBA-MOL CELL BIOL L 1867 (8): 159159, 1-11
https://doi.org/10.1016/j.bbalip.2022.159159
Vanselow, J.; Conley, A.J.; Corbin, C. J.; Berger, T (2021):
Genomic Structure of the Porcine CYP19 Locus and Expression of the CYP19A3 Paralog . Genes-Basel 12 (4): 533, 1-12
https://doi.org/10.3390/genes12040533
Yenuganti, V.; Koczan, D.; Vanselow, J. (2021):
Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition. BMC Genomics 22: 486, 1-10
https://doi.org/10.1186/s12864-021-07817-6
Vanselow, J.; Conley, A. J.; Berger, T (2021):
Aromatase and the three little paralogs. Biol Reprod 105 (1): 5-6
https://doi.org/10.1093/biolre/ioab112
Berger, T; Vanselow, J.; Conley, A.J.; Almand, T.J.; Nitta-Oda, B.S. (2021):
Multifaceted epigenetic regulation of porcine testicular aromatase. Mol Cell Endocrinol 541: 111526, 1-8
https://doi.org/10.1016/j.mce.2021.111526
Vanselow, J.; Christenson, L. K.; Pate, J. L. (2020):
Editorial: Regulation of dynamic changes and remodeling events during the formation, rescue and regression of the corpus luteum. Front Endocrinol 11: 244, 1-2
https://doi.org/10.3389/fendo.2020.00244
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
https://doi.org/10.3389/fendo.2020.00087
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
https://doi.org/10.1038/s41598-020-60935-1
Baddela, V. S.; Sharma, A.; Vanselow, J. (2020):
Non-esterified fatty acids in the ovary: friends or foes?. Reprod Biol Endocrin 18: 60, 1-14
https://doi.org/10.1186/s12958-020-00617-9
Pöhland, R.; Souza Cáceres, M. B.; Datta, T. K.; Vanselow, J.; Martins, M.I.M.; Silva, W.A.L.; Cardoso, C. T.; Melo Sterza, F. A. (2020):
Influence of long-term thermal stress on the in vitro maturation on embryo development and Heat Shock Protein abundance in zebu cattle. Anim Reprod 17 (3): e20190085, 1-10
https://doi.org/10.1590/1984-3143-AR2019-0085
Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
https://doi.org/10.1186/s12864-019-5657-6
Sharma, A.; Baddela, V. S.; Becker, F.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
https://doi.org/10.1530/EC-19-0011
Baddela, V. S.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
Global gene expression analysis indicates that small luteal cells are involved in extracellular matrix modulation and immune cell recruitment in the bovine corpus luteum. Mol Cell Endocrinol 474: 201-213
https://doi.org/10.1016/j.mce.2018.03.011
Baufeld, A.; Vanselow, J. (2018):
Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage. Reprod Biol Endocrin 16: 15, 1-11
https://doi.org/10.1186/s12958-018-0332-3
Baddela, V. S.; Sharma, A.; Viergutz, T.; Koczan, D.; Vanselow, J. (2018):
Low oxygen levels induce early luteinization associated changes in bovine granulosa cells. Front Physiol 9: 1066, 1-15
https://doi.org/10.3389/fphys.2018.01066
Baddela, V. S.; Sharma, A.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
mRNA microarraydata of FACS purified bovine small and large luteal cells. Data in brief 19: 737-742
https://doi.org/10.1016/j.dib.2018.05.029
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. 139: e58208
https://doi.org/doi:10.3791/58208
Baufeld, A.; Koczan, D.; Vanselow, J. (2017):
Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density. Reprod Biol Endocrin 15: 3, 1-14
https://dx.doi.org/10.1186/s12958-016-0221-6
Yenuganti, V.; Vanselow, J. (2017):
Cultured bovine granulosa cells rapidly lose important features of their identity and functionality but partially recover under long-term culture conditions. Cell Tissue Res 368 (2): 397-403
https://dx.doi.org/10.1007/s00441-017-2571-6