Dr. agr. Eduard Muráni
Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
- Regulation der mRNA Expression
- Verbindung von genotypischer mit phänotypischer Variation
Lebenslauf
- 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
- 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
- 2003: Promotion in den Agrarwissenschaften
- 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
- 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei
Publikationen
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways. Physiol Genomics 44 (16): 811-818
https://dx.doi.org/10.1152/physiolgenomics.00050.2012
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model. BMC Genomics 13 (1): 93-107
https://dx.doi.org/10.1186/1471-2164-13-93
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny. Plos One 7 (3): 1-9
https://dx.doi.org/10.1371/journal.pone.0034519
Du, Y.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Flexible and efficient genome tiling design with penalized uniqueness score. BMC Bioinformatics 13: 323-334
https://dx.doi.org/10.1186/1471-2105-13-323
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds - indications of prenatal initiation of postnatal phenotypic differences. BMC Dev Biol 12: 13-29
https://dx.doi.org/10.1186/1471-213x-12-13
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Maternal dietary protein restriction and excess affects offspring gene expression and methylation of non-SMC subunits of condensin I in liver and skeletal muscle. Epigenetics-US 7 (3): 239-252
https://dx.doi.org/10.4161/epi.7.3.19183
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Somatic cytochrome c (CYCS) gene expression and promoter-specific DNA methylation in a porcine model of prenatal exposure to maternal dietary protein excess and restriction. Brit J Nutr 107 (6): 791-799
https://dx.doi.org/10.1017/S0007114511003667
Altmann, S.; Muràni, E.; Metges, C. C.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2012):
Effect of gestational protein deficiency and excess on hepatic expression of genes related to cell cycle and proliferation in offspring from late gestation to finishing phase in pig. Mol Biol Rep 39 (6): 7095-7104
https://dx.doi.org/10.1007/s11033-012-1541-z
Muràni, E.; Reyer, H.; Ponsuksili, S.; Fritschka, S.; Wimmers, K. (2012):
A substitution in the ligand binding domain of the porcine glucocorticoid receptor affects activity of the adrenal gland. Plos One 7 (9): 1-10
https://dx.doi.org/10.1371/journal.pone.0045518
Brunner, R. M.; Srikanchai, T.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2012):
Genes with expression levels correlating to drip loss prove association of their polymorphism with water holding capacity of pork. Mol Biol Rep 39 (1): 97-107
https://dx.doi.org/10.1007/s11033-011-0714-5
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs. J Anim Sci 90 (1): 1-15
https://dx.doi.org/10.2527/jas.2011-4269
Wimmers, K.; Do, V. A. K.; Schütze, S.; Muràni, E.; Ponsuksili, S. (2011):
The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes. BMC Proceedings 5 (Suppl.4): S19, 1-4
https://dx.doi.org/10.1186/1753-6561-5-S4-S19
Do, V. A. K.; Ponsuksili, S.; Muràni, E.; Wimmers, K. (2011):
Polymorphic sites in the 5'-region of the porcine C8A gene. Arch Tierzucht 54 (4): 430-438
Ponsuksili, S.; Muràni, E.; Brand, B.; Schwerin, M.; Wimmers, K. (2011):
Integrating expression profiling and whole-genome association for dissection of fat traits in a porcine model. J Lipid Res 52 (4): 668-678
https://dx.doi.org/10.1194/Jlr.M013342
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2011):
A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model. Plos One 6 (7): 1-12
https://dx.doi.org/10.1371/journal.pone.0021691
Muràni, E.; Ponsuksili, S.; D´Eath, R. B.; Turner, S.P.; Evans, G.; Thölking, L.; Kurt, E.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2011):
Differential mRNA expression of genes in the porcine adrenal gland associated with psychosocial stress. J Mol Endocrinol 46 (3): 165-174
https://dx.doi.org/10.1530/Jme-10-0147
Wimmers, K.; Dolle, K.; Leeb, T.; Schellander, K.; Brunner, R. M.; Muràni, E.; Ponsuksili, S. (2010):
Identification of porcine candidate genes for water-holding capacity using QTL-region-specific BAC-arrays. In: Proceedings of the 9th World Congress on Genetics Applied to Livestock Production (Gesellschaft für Tierzuchtwissenschaften e.V., Hrsg.) (978-00-031608) (2010): 455
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2010):
Functional genomics and genetical genomics approaches towards elucidating networks of genes affecting meat performance in pigs. Briefings in Functional Genomics 9: 251-258
https://dx.doi.org/10.1093/bfgp/elq003
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2010):
Expression QTL and their applications in genetic improvement in farm animals.
https://dx.doi.org/10.1079/PAVSNNR20105012