Dr. agr. Eduard Muráni
Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
- Regulation der mRNA Expression
- Verbindung von genotypischer mit phänotypischer Variation
Lebenslauf
- 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
- 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
- 2003: Promotion in den Agrarwissenschaften
- 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
- 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei
Publikationen
Adler, M.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
PBMC transcription profiles of pigs with divergent humoral immune responses and lean growth performance. Int J Biol Sci 9 (9): 907-916
https://dx.doi.org/10.1371/journal.pone.0076705
Huynh, L. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
UBE3B and ZRANB1 polymorphisms and transcript abundance are associated with water holding capacity of porcine M. longissimus dorsi. Meat Sci 95 (2): 166-172
https://dx.doi.org/10.1016/j.meatsci.2013.04.033
Muràni, E.; Ponsuksili, S.; Reyer, H.; Wittenburg, D.; Wimmers, K. (2013):
Expression variation of the porcine ADRB2 has a complex genetic background. Mol Genet genomics 288 (11): 615-625
https://dx.doi.org/10.1007/s00438-013-0776-2
Reyer, H.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2013):
Transcript variants of the porcine glucocorticoid receptor gene (NR3C1). Gen Comp Endocr 189: 127-133
https://dx.doi.org/10.1016/j.ygcen.2013.04.038
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2013):
Dietary protein restriction and excess of pregnant German Landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring. J Nutr Biochem 24 (2): 484-495
https://dx.doi.org/10.1016/j.jnutbio.2012.01.011
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
Association of TLR5 sequence variants and mRNA level with cytokine transcription in pigs. Immunogenetics 65 (2): 125-132
https://dx.doi.org/10.1007/s00251-012-0662-9
Rangkasenee, N.; Muràni, E.; Brunner, R. M.; Schellander, K.; Cinar, M. U.; Scholz, A. M.; Luther, H.; Hofer, A.; Ponsuksili, S.; Wimmers, K. (2013):
KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs. Mol Biol Rep 39 (4): 2859-2866
https://dx.doi.org/10.1007/s11033-012-2301-9
Chomwisarutkun, K.; Muràni, E.; Brunner, R. M.; Ponsuksili, S.; Wimmers, K. (2013):
QTL region-specific microarrays reveal differential expression of positional candidate genes of signaling pathways associated with the liability for the inverted teat defect. Anim Genet 44 (2): 139-148
https://dx.doi.org/10.1111/j.1365-2052.2012.02378.x
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Association of TLR4 polymorphism with cytokine expression level and pulmonary lesion score in pigs. Mol Biol Rep 39 (6): 7003-7009
https://dx.doi.org/10.1007/s11033-012-1530-2
Do, V. A. K.; Ponsuksili, S.; Muràni, E.; Huynh, L. T. P.; Brunner, R. M.; Wimmers, K. (2012):
Detection of a polymorphic site of the porcine C8G gene and evaluation of association with haemolytic complement activity. Arch Tierzucht 55 (3): 255-262
Ponsuksili, S.; Muràni, E.; Schwerin, M.; Schellander, K.; Tesfaye, D.; Wimmers, K. (2012):
Gene expression and DNA-methylation of bovine pretransfer endometrium depending on its receptivity after in vitro-produced embryo transfer. Plos One 7 (8): 1-13
https://dx.doi.org/10.1371/journal.pone.0042402
Ponsuksili, S.; Du, Y.; Muràni, E.; Schwerin, M.; Wimmers, K. (2012):
Elucidating molecular networks that either affect or respond to plasma cortisol concentration in target tissues of liver and muscle. Genetics 192 (3): 1109-1122
https://dx.doi.org/10.1534/genetics.112.143081
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways. Physiol Genomics 44 (16): 811-818
https://dx.doi.org/10.1152/physiolgenomics.00050.2012
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model. BMC Genomics 13 (1): 93-107
https://dx.doi.org/10.1186/1471-2164-13-93
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny. Plos One 7 (3): 1-9
https://dx.doi.org/10.1371/journal.pone.0034519
Du, Y.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Flexible and efficient genome tiling design with penalized uniqueness score. BMC Bioinformatics 13: 323-334
https://dx.doi.org/10.1186/1471-2105-13-323
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds - indications of prenatal initiation of postnatal phenotypic differences. BMC Dev Biol 12: 13-29
https://dx.doi.org/10.1186/1471-213x-12-13
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Maternal dietary protein restriction and excess affects offspring gene expression and methylation of non-SMC subunits of condensin I in liver and skeletal muscle. Epigenetics-US 7 (3): 239-252
https://dx.doi.org/10.4161/epi.7.3.19183
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Somatic cytochrome c (CYCS) gene expression and promoter-specific DNA methylation in a porcine model of prenatal exposure to maternal dietary protein excess and restriction. Brit J Nutr 107 (6): 791-799
https://dx.doi.org/10.1017/S0007114511003667
Altmann, S.; Muràni, E.; Metges, C. C.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2012):
Effect of gestational protein deficiency and excess on hepatic expression of genes related to cell cycle and proliferation in offspring from late gestation to finishing phase in pig. Mol Biol Rep 39 (6): 7095-7104
https://dx.doi.org/10.1007/s11033-012-1541-z