Dr. agr. Eduard Muráni

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
  • Regulation der mRNA Expression
  • Verbindung von genotypischer mit phänotypischer Variation

Lebenslauf

  • 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
  • 2003: Promotion in den Agrarwissenschaften
  • 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
  • 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei

Publikationen

Oster, M.; Scheel, M.; Muràni, E.; Ponsuksili, S.; Zebunke, M.; Puppe, B.; Wimmers, K. (2015):
The fight-or-flight response is associated with PBMC expression profiles related to immune defence and recovery in swine. Plos One 10 (3): e0120153, 1-15
https://dx.doi.org/10.1371/journal.pone.0120153
Görres, A.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Analysis of non-synonymous SNPs of the porcine SERPINA6 gene as potential causal variants for a QTL affecting plasma cortisol levels on SSC7. Anim Genet 46 (3): 239-246
https://dx.doi.org/10.1111/age.12276
Muràni, E.; Reyer, H.; Görres, A.; Tuchscherer, A.; Kanitz, E.; Ponsuksili, S.; Wimmers, K. (2014):
From phenotype to QTN and back: Identification and characterization of a genetic variant of the porcine glucocorticoid receptor with a major effect on HPA axis activity. In: Proceedings / 10th World Congress of Genetics Applied to Livestock Production (https://asas.org/wcgalp-proceedings) (https://asas.org/wcgalp-proceedings/species-breeding-swine): 371
Oster, M.; Muràni, E.; Ponsuksili, S.; D´Eath, R. B.; Turner, S.P.; Evans, G.; Thölking, L.; Kurt, E.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2014):
Transcriptional responses of PBMC in psychosocially stressed animals indicate an alerting of the immune system in female but not in castrated male pigs. BMC Genomics 15: 967-978
https://dx.doi.org/10.1186/1471-2164-15-967
Oster, M.; Muràni, E.; Ponsuksili, S.; D´Eath, R. B.; Turner, S.P.; Evans, G.; Thölking, L.; Kurt, E.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2014):
Hepatic expression patterns in psychosocially high-stressed pigs suggest mechanisms following allostatic principles. Physiol Behav 128: 159-165
https://dx.doi.org/10.1016/j.physbeh.2014.02.014
Ponsuksili, S.; Muràni, E.; Trakooljul, N.; Schwerin, M.; Wimmers, K. (2014):
Discovery of candidate genes for muscle traits based on GWAS supported by eQTL-analysis. Int J Biol Sci 10 (3): 327-337
https://dx.doi.org/10.7150/ijbs.8134
Du, Y.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2014):
biomvRhsmm: genomic segmentation with hidden semi-Markov model. BioMed Res Int 2014: 1-11
https://dx.doi.org/10.1155/2014/910390
Loan, H. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2014):
UBXN1 polymorphism and its expression in porcine M. longissimus dorsi are associated with water holding capacity. Mol Biol Rep 41 (3): 1411-1418
https://dx.doi.org/10.1007/s11033-013-2985-5
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2014):
High- and low-protein gestation diets do not provoke common transcriptional responses representing universal target-pathways in muscle and liver of porcine progeny. Acta Physiol 210 (1): 202-214
https://dx.doi.org/10.1111/Apha.12192
Reyer, H.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2014):
Association of N-terminal domain polymorphisms of the porcine glucocorticoid receptor with carcass composition and meat quality traits. Anim Genet 45 (1): 125-129
https://dx.doi.org/10.1111/age.12083.
Du, Y.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
BiomvRCNS: copy number variation study and segmentation for multivariate biological data. Schriftenreihe / Leibniz-Institut für Nutztierbiol 21: 11-14
Huynh, L. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
UBE3B and TRIP12 polymorphisms and transcript abundance are associated with water holding capacity of porcine m. longissimus dorsi . Schriftenreihe / Leibniz-Institut für Nutztierbiol 21: 27-30
Loan, H. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
Novel SNPs of the porcine TRIP12 are associated with water holding capacity of meat. Czech J Anim Sci 58 (11): 525-533
Siengdee, P.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2013):
Transcriptional profiling and miRNA-dependent regulatory network analysis of longissimus dorsi muscle during prenatal and adult stages in two distinct pig breeds. Anim Genet 44 (4): 398-407
https://dx.doi.org/10.1111/Age.12032
Adler, M.; Muràni, E.; Brunner, R. M.; Ponsuksili, S.; Wimmers, K. (2013):
Transcriptomic response of porcine PBMCs to vaccination with tetanus toxoid as a model antigen. Plos One 8 (3): 1-8
https://dx.doi.org/10.1371/journal.pone.0058306
Rangkasenee, N.; Muràni, E.; Brunner, R. M.; Schellander, K.; Cinar, M. U.; Luther, H.; Hofer, A.; Stoll, M.; Witten, A.; Ponsuksili, S.; Wimmers, K. (2013):
Genome-wide association identifies TBX5 as candidate gene for osteochondrosis providing a functional link to cartilage perfusion as initial factor. Front Genet 4: 78
https://dx.doi.org/10.3389/fgene.2013.00078
Ponsuksili, S.; Du, Y.; Hadlich, F.; Siengdee, P.; Muràni, E.; Schwerin, M.; Wimmers, K. (2013):
Correlated mRNAs and miRNAs from co-expression and regulatory networks affect porcine muscle and finally meat properties. BMC Genomics 14: 533-550
https://dx.doi.org/10.1186/1471-2164-14-533
Rangkasenee, N.; Muràni, E.; Schellander, K.; Cinar, M. U.; Ponsuksili, S.; Wimmers, K. (2013):
Gene expression profiling of articular cartilage reveals functional pathways and networks of candidate genes for osteochondrosis in pigs. Physiol Genomics 45 (18): 856-865
https://dx.doi.org/10.1152/physiolgenomics.00055.2013
Adler, M.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
PBMC transcription profiles of pigs with divergent humoral immune responses and lean growth performance. Int J Biol Sci 9 (9): 907-916
https://dx.doi.org/10.1371/journal.pone.0076705
Huynh, L. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
UBE3B and ZRANB1 polymorphisms and transcript abundance are associated with water holding capacity of porcine M. longissimus dorsi. Meat Sci 95 (2): 166-172
https://dx.doi.org/10.1016/j.meatsci.2013.04.033