Dr. agr. Eduard Muráni
Forschungsinteressen
- Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
- Regulation der mRNA Expression
- Verbindung von genotypischer mit phänotypischer Variation
Lebenslauf
- 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
- 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
- 2003: Promotion in den Agrarwissenschaften
- 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
- 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei
Publikationen
Ponsuksili, S.; Reyer, H.; Trakooljul, N.; Muràni, E.; Wimmers, K. (2016):
Single- and Bayesian multi-marker genome-wide association for haematological parameters in pigs. Plos One 11 (7): e0159212, 1-14
https://dx.doi.org/10.1371/journal.pone.0159212
Liu, X.; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2016):
MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities. BMC Genomics 17: 531, 1-14
https://dx.doi.org/10.1186/s12864-016-2850-8
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Transient shifts of incubation temperature reveal immediate and long-term transcriptional response in chicken breast muscle underpinning resilience and phenotypic plasticity. Plos One 11 (9): e0162485, 1-17
https://dx.doi.org/10.1371/journal.pone.0162485
Oster, M.; Just, F.; Büsing, K.; Wolf, C.; Polley, C.; Vollmar, B.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2016):
Toward improved phosphorus efficiency in monogastrics - interplay of serum, minerals, bone and immune system after divergent dietary phosphorus supply in swine. Am J Physiol-Reg I 310 (10): R917-R925
https://dx.doi.org/10.1152/ajpregu.00215.2015
Oster, M.; Nuchchanart, W.; Trakooljul, N.; Muràni, E.; Zeyner, A.; Wirthgen, E.; Hoeflich, A.; Ponsuksili, S.; Wimmers, K. (2016):
Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight. Eur J Nutr 55 (4): 1717-1727
https://dx.doi.org/10.1007/s00394-015-0990-2
Wimmers, K.; Muràni, E.; Ponsuksili, S. (2015):
Genetic factors on reproductive traits in pigs. Proc Soc. Nutr. Physiol. 24: 185
Liu, X; Du, Y.; Trakooljul, N.; Brand, B.; Muràni, E.; Krischek, C.; Wicke, M.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
Transcriptional profile of muscle association with mitochondrial respiratory activity, metabolic enzymes and muscle fiber. Schriftenreihe / Leibniz-Institut für Nutztierbiol 24: 37-40
Siengdee, P.; Trakooljul, N.; Muràni, E.; Brand, B.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
Pre- and post-natal muscle microRNA expression profiles of two pig breeds differing in muscularity. Gene 561 (2): 190-198
https://dx.doi.org/10.1016/j.gene.2015.02.035
Ponsuksili, S.; Siengdee, P.; Du, Y.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K. (2015):
Identification of common regulators of genes in co-expression networks affecting muscle and meat properties. Plos One 10 (4): e0123678, 1-18
https://dx.doi.org/10.1371/journal.pone.0123678
Siengdee, P.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
MicroRNAs regulate cellular ATP levels by targeting mitochondrial energy metabolism genes during C2C12 myoblast differentiation. Plos One 10 (5): e0127850, 1-20
https://dx.doi.org/10.1371/journal.pone.0127850
Adler, M.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2015):
PBMC transcriptomic responses to primary and secondary vaccination differ due to divergent lean growth and antibody titers in a pig model. Physiol Genomics 47 (10): 470-478
https://dx.doi.org/10.1152/physiolgenomics.00015.2015
Liu, X; Du, Y.; Trakooljul, N.; Brand, B.; Muràni, E.; Krischek, C.; Wicke, M.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
Muscle transcriptional profile based on muscle fiber, mitochondrial respiratory activity, and metabolic enzymes. Int J Biol Sci 11 (12): 1348-1362
https://dx.doi.org/10.7150/ijbs.13132
Ponsuksili, S.; Zebunke, M.; Muràni, E.; Trakooljul, N.; Krieter, J.; Puppe, B.; Schwerin, M.; Wimmers, K. (2015):
Integrated Genome-wide association and hypothalamus eQTL studies indicate a link between the circadian rhythm-related gene PER1 and coping behavior. Sci Rep-UK 5: 16264, 1-14
https://dx.doi.org/10.1038/srep16264
Reyer, H.; Hawken, R.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2015):
The genetics of feed conversion efficiency traits in a commercial broiler line. Sci Rep-UK 5: 16387, 1-11
https://dx.doi.org/10.1038/srep16387
Jaeger, A.; Fritschka, S.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Identification and functional characterization of cis-regulatory elements controlling expression of the porcine ADRB2 gene. Int J Biol Sci 11 (9): 1006-1015
https://dx.doi.org/10.7150/ijbs.12456
Jaeger, A.; Bardehle, D.; Oster, M.; Günther, J.; Muràni, E.; Ponsuksili, S.; Wimmers, K.; Kemper, N. (2015):
Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro. Vet Res 46: 50, 1-18
https://dx.doi.org/10.1186/s13567-015-0178-z
Oster, M.; Scheel, M.; Muràni, E.; Ponsuksili, S.; Zebunke, M.; Puppe, B.; Wimmers, K. (2015):
The fight-or-flight response is associated with PBMC expression profiles related to immune defence and recovery in swine. Plos One 10 (3): e0120153, 1-15
https://dx.doi.org/10.1371/journal.pone.0120153
Görres, A.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Analysis of non-synonymous SNPs of the porcine SERPINA6 gene as potential causal variants for a QTL affecting plasma cortisol levels on SSC7. Anim Genet 46 (3): 239-246
https://dx.doi.org/10.1111/age.12276
Muràni, E.; Reyer, H.; Görres, A.; Tuchscherer, A.; Kanitz, E.; Ponsuksili, S.; Wimmers, K. (2014):
From phenotype to QTN and back: Identification and characterization of a genetic variant of the porcine glucocorticoid receptor with a major effect on HPA axis activity. In: Proceedings / 10th World Congress of Genetics Applied to Livestock Production (https://asas.org/wcgalp-proceedings) (https://asas.org/wcgalp-proceedings/species-breeding-swine): 371