Dr. agr. Eduard Muráni
Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Arbeitsgruppe Physiologische Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
- Regulation der mRNA Expression
- Verbindung von genotypischer mit phänotypischer Variation
Lebenslauf
- 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
- 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
- 2003: Promotion in den Agrarwissenschaften
- 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
- 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei
Publikationen
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Methling, K.; Lalk, M.; Murani, E.; Wimmers, K. (2019):
Genetic regulation of liver metabolites and transcripts linking to biochemical-llinical parameters. Front Genet 10: 348, 1-15
https://doi.org/10.3389/fgene.2019.00348
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
https://doi.org/10.1186/s12864-019-5880-1
Gley, K.; Murani, E.; Haack, F.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behav Brain Res 372: 112038, 1-13
https://doi.org/10.1016/j.bbr.2019.112038
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
https://doi.org/10.1080/15476286.2019.1657743
Gley, K.; Muráni, E.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Transcriptome profiles of hypothalamus and adrenal gland linked to haplotype related to coping behavior in pigs. Sci Rep-UK 9: 13038, 1-14
https://doi.org/10.1038/s41598-019-49521-2
Muráni, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2019):
Transcriptome responses to dexamethasone depending on dose and glucocorticoid receptor sensitivity in the liver. Front Genet 10: 559, 1-12
https://doi.org/10.3389/fgene.2019.00559
Li, Z.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A.; Metges, C. C.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2019):
Kinetics of physiological and behavioural responses in endotoxemic pigs with or without dexamethasone treatment. Int J Mol Sci 20 (6): 1393, 1-15
https://doi.org/10.3390/ijms20061393
Gerlinger, Ch.; Oster, M.; Borgelt, L.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Polley, C.; Vollmar, B.; Reichel, M.; Wolf, P; Wimmers, K. (2019):
Physiological and transcriptional responses in weaned piglets fed diets with varying phosphorus and calcium levels. Nutrients 11 (2): 436, 1-15
https://doi.org/10.3390/nu11020436
Naraballobh, W; Trakooljul, N.; Muráni, E.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2018):
miRNAs regulate acute transcriptional changes in broiler embryos in response to modification of incubation temperature. Sci Rep-UK 8: 11371, 1-12
https://doi.org/10.1038/s41598-018-29316-7
Reyer, H.; Metzler-Zebeli, B.U.; Trakooljul, N.; Oster, M.; Muráni, E.; Ponsuksili, S.; Hadlich, F.; Wimmers, K. (2018):
Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens. Sci Rep-UK 8: 12903, 1-9
https://doi.org/10.1038/s41598-018-31072-7
Reyer, H.; Oster, M.; Magowan, E.; Muráni, E.; Sauerwein, H.; Dannenberger, D.; Kuhla, B.; Ponsuksili, S.; Wimmers, K. (2018):
Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients. Physiol Genomics 50 (9): 726-734
Henry Reyer,
Michael Oster,
Eduard Muráni,
Dirk Dannenberger,
Björn Kuhla,
Siriluck Wimmers,
Klaus Wimmers
https://doi.org/10.1152/physiolgenomics.00021.2018
Just, F.; Oster, M.; Büsing, K.; Borgelt, L.; Muráni, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2018):
Lowered dietary phosphorus affects intestinal and renal gene expression to maintain mineral homeostasis with immunomodulatory implications in weaned piglets. BMC Genomics 19: 207, 1-11
https://doi.org/10.1186/s12864-018-4584-2
Just, F.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Oster, M.; Wimmers, K. (2018):
Genetic variants of major genes contributing to phosphate and calcium homeostasis and their association with serum parameters in pigs. J Appl Genet 59 (3): 325-333
https://doi.org/10.1007/s13353-018-0449-2
Oster, M.; Gerlinger, Ch.; Heide, K.; Just, F.; Borgelt, L.; Wolf, C.; Polley, C.; Vollmar, B.; Muráni, E.; Ponsuksili, S.; Wimmers, K. (2018):
Lower dietary phosphorus supply in pigs match both animal welfare aspects and resource efficiency. Ambio 47 (Suppl. 1): 20-29
https://doi.org/10.1007/s13280-017-0969-8
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2017):
Genetic architecture and regulatory impact on hepatic microRNA expression linked to immune and metabolic traits. Open Biol 7 (11): 170101, 1-11
https://dx.doi.org/10.1098/rsob.170101
Liu, X; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
Mitochondrial-nuclear crosstalk, haplotype and copy number variation distinct in muscle fiber type, mitochondrial respiratory and metabolic enzyme activities. Sci Rep-UK 7: 14024, 1-12
https://dx.doi.org/10.1038/s41598-017-14491-w
Jaeger, A.; Hadlich, F.; Kemper, N.; Lübke-Becker, A.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
MicroRNA expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli in vitro. BMC Genomics 18: 660, 1-14
https://dx.doi.org/10.1186/s12864-017-4070-2
Reyer, H.; Varley, P. F.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Genetics of body fat mass and related traits in a pig population selected for leanness. Sci Rep-UK 7: 9118, 1-9
https://dx.doi.org/10.1038/s41598-017-08961-4
Reyer, H.; Shirali, M.; Ponsuksili, S.; Muràni, E.; Varley, P. F.; Jensen, J.; Wimmers, K. (2017):
Exploring the genetics of feed efficiency and feeding behaviour traits in a pig line highly selected for performance characteristics. Mol Genet genomics 292 (5): 1001-1011
https://dx.doi.org/10.1007/s00438-017-1325-1
Oster, M.; Trakooljul, N.; Reyer, H.; Zeyner, A.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Sex-specific muscular maturation responses following prenatal exposure to methylation-related micronutrients in pigs. Nutrients 9 (1): 74-86
https://dx.doi.org/10.3390/nu9010074