Dr. agr. Eduard Muráni
Forschungsinteressen
- Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
- Regulation der mRNA Expression
- Verbindung von genotypischer mit phänotypischer Variation
Lebenslauf
- 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
- 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
- 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
- 2003: Promotion in den Agrarwissenschaften
- 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
- 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei
Publikationen
Reyer, H.; Sjöberg, P. J. R.; Oster, M.; Wubuli, A.; Murani, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2021):
Mineral Phosphorus Supply in Piglets Impacts the Microbial Composition and Phytate Utilization in the Large Intestine. Microorganisms 9 (9): 1197, 1-10
https://doi.org/10.3390/microorganisms9061197
Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Omotoso, A. O.; Iqbal, M. A.; Murani, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Transcriptional responses in jejunum of two layer chicken strains following variations in dietary calcium and phosphorus levels. BMC Genomics 22: 485, 1-12
https://doi.org/10.1186/s12864-021-07814-9
Li, Z.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K.; Murani, E. (2021):
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. Virulence 12 (1): 1808-1824
https://doi.org/10.1080/21505594.2021.1948276
Gerlinger, Ch.; Oster, M.; Reyer, H.; Polley, C.; Vollmar, B.; Muráni, E.; Wimmers, K.; Wolf, P. (2021):
Effects of excessive or restricted phosphorus and calcium intake during early life on markers of bone architecture and composition in pigs. J Anim Physiol An N 105 (S. 2): 52-62
https://doi.org/10.1111/jpn.13286
Abousoliman, I.; Reyer, H.; Oster, M.; Muráni, E.; Mourad, M.; Abdel-Salam Rashed, M.; Mohamed, I.; Wimmers, K. (2020):
Analysis of candidate genes for growth and milk performance traits in the Egyptian Barki sheep. Animals 10: 197, 1-13
https://doi.org/10.3390/ani10020197
Reyer, H.; Oster, M.; McCormack, U. M.; Muráni, E.; Gardiner, G. E.; Ponsuksili, S.; Lawlor, P. G.; Wimmers, K. (2020):
Host-microbiota interactions in ileum and caecum of pigs divergent in feed efficiency contribute to nutrient utilization. Microorganisms 8: 563, 1-12
https://doi.org/10.3390/microorganisms8040563
Ponsuksili, S.; Reyer, H.; Hadlich, F.; Weber, F. M.; Trakooljul, N.; Oster, M.; Siengdee, P.; Muráni, E.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2020):
Identification of the key molecular drivers of phosphorus utilization based on host miRNA-mRNA and gut microbiome interactions. Int J Mol Sci 21: 2818, 1-18
https://doi.org/10.3390/ijms21082818
Wubuli, A.; Gerlinger, Ch.; Reyer, H.; Oster, M.; Murani, E.; Trakooljul, N.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2020):
Reduced phosphorus intake throughout gestation and lactation of sows is mitigated by transcriptional adaptations in kidney and intestine. BMC Genomics 21: 626, 1-11
https://doi.org/10.1186/s12864-020-07049-0
Kasper, C.; Ribeiro, D.; Almeida, A. M. de; Larzul, C.; Liaubet, L.; Murani, E. (2020):
Omics Application in Animal Science—A Special Emphasis on Stress Response and Damaging Behaviour in Pigs. Genes-Basel 11 (8): 920, 1-24
https://doi.org/10.3390/genes11080920
Li, Z.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A.; Metges, C. C.; Trakooljul, N.; Wimmers, K.; Murani, E. (2020):
A natural Ala610Val substitution causing glucocorticoid receptor hypersensitivity aggravates consequences of endotoxemia. Brain Behav Immun 90: 174-183
https://doi.org/10.1016/j.bbi.2020.08.009
Oster, M.; Reyer, H.; Keiler, J.; Ball, E.; Mulvenna, C.; Muráni, E.; Ponsuksili, S.; Wimmers, K. (2020):
Comfrey (Symphytum spp.) as an alternative field crop contributing to closed agricultural cycles in chicken feeding. Sci Total Environ 742: 140490, 1-9
https://doi.org/10.1016/j.scitotenv.2020.140490
Oster, M.; Reyer, H.; Trakooljul, N.; Weber, F. M.; Xi, L.; Muráni, E.; Ponsuksili, S.; Rodehutscord, M.; Bennewitz, J.; Wimmers, K. (2020):
Ileal transcriptome profiles of Japanese quail divergent in phosphorus utilization. Int J Mol Sci 21: 2762, 1-13
https://doi.org/10.3390/ijms21082762
Benítez, R.; Trakooljul, N.; Nunez, Y.; Isabel, B.; Murani, E.; de Mercado, E.; Gómez-Izquierdo, E.; Garcia-Casco, J.; López-Bote, C.; Wimmers, K.; Óvilo, C. (2019):
Breed, diet, and interaction effects on adipose tissue transcriptome in Iberian and Duroc pigs fed different energy sources. Genes-Basel 10 (8): 589, 1-24
https://doi.org/10.3390/genes10080589
Wubuli, A.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Wolf, P.; Oster, M.; Wimmers, K. (2019):
Tissue-wide gene expression analysis of sodium/phosphate co-transporters in pigs. Int J Mol Sci 20 (22): 5576, 1-12
https://doi.org/10.3390/ijms20225576
Reyer, H.; Oster, M.; Wittenburg, D.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2019):
Genetic contribution to variation in blood calcium, phosphorus, and alkaline phosphatase activity in pigs. Front Genet 10: 590, 1-12
https://doi.org/10.3389/fgene.2019.00590
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Methling, K.; Lalk, M.; Murani, E.; Wimmers, K. (2019):
Genetic regulation of liver metabolites and transcripts linking to biochemical-llinical parameters. Front Genet 10: 348, 1-15
https://doi.org/10.3389/fgene.2019.00348
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
https://doi.org/10.1186/s12864-019-5880-1
Gley, K.; Murani, E.; Haack, F.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behav Brain Res 372: 112038, 1-13
https://doi.org/10.1016/j.bbr.2019.112038
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
https://doi.org/10.1080/15476286.2019.1657743
Gley, K.; Muráni, E.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Transcriptome profiles of hypothalamus and adrenal gland linked to haplotype related to coping behavior in pigs. Sci Rep-UK 9: 13038, 1-14
https://doi.org/10.1038/s41598-019-49521-2