Dr. agr. Eduard Muráni

+49 38208 68-702
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Genombiologie
Abteilung Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
  • Regulation der mRNA Expression
  • Verbindung von genotypischer mit phänotypischer Variation

Lebenslauf

  • 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
  • 2003: Promotion in den Agrarwissenschaften
  • 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
  • 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei

Publikationen

Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER 13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity. Sci Rep-UK 12: 16293, 1-13
https://doi.org/10.1038/s41598-022-20682-x
Li, Z.; Hadlich, F.; Wimmers, K.; Murani, E. (2022):
Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs. Front Immunol 13: 1
https://doi.org/10.3389/fimmu.2022.976454
Gerlinger, Ch.; Oster, M.; Reyer, H.; Polley, C.; Vollmar, B.; Muráni, E.; Wimmers, K.; Wolf, P. (2021):
Effects of excessive or restricted phosphorus and calcium intake during early life on markers of bone architecture and composition in pigs. J Anim Physiol An N 105 (S. 2): 52-62
https://doi.org/10.1111/jpn.13286
Li, Z.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K.; Murani, E. (2021):
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. Virulence 12 (1): 1808-1824
https://doi.org/10.1080/21505594.2021.1948276
Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Omotoso, A. O.; Iqbal, M. A.; Murani, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Transcriptional responses in jejunum of two layer chicken strains following variations in dietary calcium and phosphorus levels. BMC Genomics 22: 485, 1-12
https://doi.org/10.1186/s12864-021-07814-9
Reyer, H.; Sjöberg, P. J. R.; Oster, M.; Wubuli, A.; Murani, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2021):
Mineral Phosphorus Supply in Piglets Impacts the Microbial Composition and Phytate Utilization in the Large Intestine. Microorganisms 9 (9): 1197, 1-10
https://doi.org/10.3390/microorganisms9061197
Abousoliman, I.; Reyer, H.; Oster, M.; Murani, E.; Mohamed, I.; Wimmers, K. (2021):
Genome-Wide SNP Analysis for Milk Performance Traits in Indigenous Sheep: A Case Study in the Egyptian Barki Sheep. Animal 11 (6): 1-9
https://doi.org/10.3390/ani11061671
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Murani, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Jejunal transcriptomic profiling of two layer strains throughout the entire production period. Sci Rep-UK 11: 20086, 1-11
https://doi.org/10.1038/s41598-021-99566-5
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
Prenatal Skeletal Muscle Transcriptome Analysis Reveals Novel MicroRNA-mRNA Networks Associated with Intrauterine Growth Restriction in Pigs. Cells-Basel 10 (5): 1007, 1-21
https://doi.org/10.3390/cells10051007
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes. Genes-Basel 12 (8): 1264, 1-16
https://doi.org/10.3390/genes12081264
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Wang, XY.; Chen, J.; Murani, E.; D´Allesandro, E.; An, Y.; Chen, C.; Li, K.; Galeano, G.; Wimmers, K.; Song, C. (2021):
A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1. Mobile DNA-UK 12 (1): 20, 1-13
https://doi.org/10.1186/s13100-021-00248-w
Chen, Cai; Zheng, Y.; Wang, Mengli; Murani, E.; D´Allesandro, E.; Moawad, A.; Wang, XY.; Wimmers, K.; Song, C. (2021):
SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor. Animals-Basel 11 (7): 1871, 1-13
https://doi.org/10.3390/ani11071871
Chen, C.; D´Allesandro, E.; Murani, E.; Zheng, Y.; Giosa, D.; Yang, R; Wang, XY.; Gao, B; Li, K.; Wimmers, K.; Song, C. (2021):
SINE jumping contributes to large-scale polymorphisms in the pig genomes. Mobile DNA-UK 12: 17, 1-17
https://doi.org/10.1186/s13100-021-00246-y
Abousoliman, I.; Reyer, H.; Oster, M.; Murani, E.; Mohamed, I.; Wimmers, K. (2021):
Genome-Wide Analysis for Early Growth-Related Traits of the Locally Adapted Egyptian Barki Sheep. Genes-Basel 12 (8): 1243, 1-10
https://doi.org/10.3390/genes12081243
Alaedin, M.; Ghaffari, M. H.; Sadri, H.; Meyer, J.; Dänicke, S.; Frahm, J.; Huber, K.; Grindler, S.; Kersten, S.; Rehage, J.; Murani, E.; Sauerwein, H. (2021):
Effects of dietary l-carnitine supplementation on the response to an inflammatory challenge in mid-lactating dairy cows: Hepatic mRNA abundance of genes involved in fatty acid metabolism. J Dairy Sci 104 (10): 11193-11209
https://doi.org/10.3168/jds.2021-20226
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
https://doi.org/10.1016/j.gpb.2020.06.007