Dr. agr. Eduard Muráni

+49 38208 68-702
Forschungsinstitut für Nutztierbiologie (FBN)
Institut für Genombiologie
Abteilung Genomik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Molekularbiologie und Genetik von Eigenschaften zur Produktion, Anpassung und zum Tierwohl von Schweinen mit Hinblick auf Stressantwort, Verhalten und Muskelentwicklung
  • Regulation der mRNA Expression
  • Verbindung von genotypischer mit phänotypischer Variation

Lebenslauf

  • 2014-heute: Wissenschaftler Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2009-2014: Nachwuchsgruppenleiter in der Abteilung Genomik am am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2004-2009: Wissenschaftler in der Abteilung Genomik am Leibniz-Institut für Nutztierbiologie (FBN)
  • 2002-2004: Postdoc im EU Projekt "PorDictor" im Institut für Tierwissenschaften der Universität Bonn
  • 2003: Promotion in den Agrarwissenschaften
  • 1998-2002: PhD Student im Institut für Tierwissenschaften der Universität Bonn
  • 1993-1998: MSc an der Univerzita Konštantína Filozofa v Nitre Slovakei

Publikationen

Du, S.; Trakooljul, N.; Palma Vera, S. E.; Murani, E.; Schuler, G.; Schön, J.; Chen, S. (2023):
Regulation of Porcine Oviduct Epithelium Functions via Progesterone and Estradiol Is Influenced by Cortisol. Endocrinology 164 (1): bqac176, 1-15
https://doi.org/10.1210/endocr/bqac176
Murani, E.; Gilbert, H.; Rauw, W. (2023):
Editorial: Genotype-by-environment interaction in farm animals: from measuring to understanding. Front Genet 14: 1267334, 1-2
https://doi.org/10.3389/fgene.2023.1267334
Gu, H.; Du, Z.; Murani, E.; D Alessandro, E.; Chen, C,; Wang, X.; Mao, J.; Wimmers, K.; Song, C. (2023):
A 314-bp SINE insertion in the ZNF2 promoter region may act as a repressor related to regulation of fat deposition in pigs. J Integr Agr 22 (2): 526-536
https://doi.org/10.1016/j.jia.2022.08.128
Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2023):
RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken. Evol Appl 16 (6): 1135-1153
https://doi.org/10.1111/eva.13557
Murani, E.; Hadlich, F. (2023):
Exploration of genotype-by-environment interactions affecting gene expression responses in porcine immune cells. Front Genet 14: 1157267, 1-9
https://doi.org/10.3389/fgene.2023.1157267
Hasan, M.; Oster, M.; Reyer, H.; Ponsuksili, S.; Murani, E.; Wolf, P.; Fischer, D.-C.; Wimmers, K. (2022):
Tissue-Wide Expression of Genes Related to Vitamin D Metabolism and FGF23 Signaling following Variable Phosphorus Intake in Pigs. METABOLITES 12 (8): 729, 1-15
https://doi.org/10.3390/metabo12080729
Li, Z.; Hadlich, F.; Wimmers, K.; Murani, E. (2022):
Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs. Front Immunol 13: 976454, 1-16
https://doi.org/10.3389/fimmu.2022.976454
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity. Sci Rep-UK 12: 16293, 1-13
https://doi.org/10.1038/s41598-022-20682-x
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER 13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Ovilo, C.; Trakooljul, N.; Nunez, Y; Hadlich, F.; Murani, E.; Ayuso, M; García-Contreras, C; Vázquez-Gómez, M.; Rey, A.; Garcia, F; García-Casco, J.; Lopez-Bote, C.; Isabel, B.; Gonzales-Bulnes, A.; Wimmers, K.; Munoz, J. (2022):
SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs. Sci Rep-UK 12: 16361, 1-16
https://doi.org/10.1038/s41598-022-20817-0
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
https://doi.org/10.1016/j.gpb.2020.06.007
Alaedin, M.; Ghaffari, M. H.; Sadri, H.; Meyer, J.; Dänicke, S.; Frahm, J.; Huber, K.; Grindler, S.; Kersten, S.; Rehage, J.; Murani, E.; Sauerwein, H. (2021):
Effects of dietary l-carnitine supplementation on the response to an inflammatory challenge in mid-lactating dairy cows: Hepatic mRNA abundance of genes involved in fatty acid metabolism. J Dairy Sci 104 (10): 11193-11209
https://doi.org/10.3168/jds.2021-20226
Abousoliman, I.; Reyer, H.; Oster, M.; Murani, E.; Mohamed, I.; Wimmers, K. (2021):
Genome-Wide Analysis for Early Growth-Related Traits of the Locally Adapted Egyptian Barki Sheep. Genes-Basel 12 (8): 1243, 1-10
https://doi.org/10.3390/genes12081243
Chen, C.; D´Allesandro, E.; Murani, E.; Zheng, Y.; Giosa, D.; Yang, R; Wang, XY.; Gao, B; Li, S.; Wimmers, K.; Song, C. (2021):
SINE jumping contributes to large-scale polymorphisms in the pig genomes. Mobile DNA-UK 12: 17, 1-17
https://doi.org/10.1186/s13100-021-00246-y
Chen, Cai; Zheng, Y.; Wang, Mengli; Murani, E.; D´Allesandro, E.; Moawad, A.; Wang, XY.; Wimmers, K.; Song, C. (2021):
SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor. Animals-Basel 11 (7): 1871, 1-13
https://doi.org/10.3390/ani11071871
Wang, XY.; Chen, J.; Murani, E.; D´Allesandro, E.; An, Y.; Chen, C.; Li, S.; Galeano, G.; Wimmers, K.; Song, C. (2021):
A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1. Mobile DNA-UK 12 (1): 20, 1-13
https://doi.org/10.1186/s13100-021-00248-w
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes. Genes-Basel 12 (8): 1264, 1-16
https://doi.org/10.3390/genes12081264