Dr. rer. nat. Dirk Dannenberger
Forschungsinstitut für Nutztierbiologie (FBN)
Leiter der Servicegruppe Metabolomics und Lipidomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiter der Servicegruppe Metabolomics und Lipidomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Regulierung des Lipidmetabolismus in Nutz- und Modelltieren (Rind, Schwein, Schaf, Maus)
- Lipidomics, Metabolomics, Fleischqualität
- Effekte von Fütterungs- (exogene PUFAs) und genetischen Faktoren auf den Lipidmetabolismus von Nutztieren
- Mechanismen der de novo Synthese von Fettsäuren in Phospholipiden und Triglyzeriden,
- Chemische Analytik (GC, GC-MS/MS, MALDI-TOF, Ag+-HPLC, TLC, biochemische Assays, Mikronährstoffe)
Lebenslauf
- seit 2018: Arbeitsgruppenleiter AG Lipidmetabolismus und muskuläre Adaptation
- 2001–2017: Wissenschaftler, Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf, Abteilung Funktion bioaktiver Lipide
- 1992–1997: Postdoc, Institut für Ostseeforschung Warnemünde, Rostock
- 1985–1989: Promotion zum Dr. rer. nat., Universität Rostock
- 1985: Abschluss zum Dipl.-Chem. in Anorganischer Chemie, Universität Rostock
Lehre
- Seit 2012: Fettqualität, Agrar- und Umweltwissenschaftliche Fakultät der Universität Rostock (M.Sc.)
- Seit 2012: Fettqualität, Agrar- und Umweltwissenschaftliche Fakultät der Universität Rostock (B.Sc.)
Publikationen
Gnott, M.; Vogel, L.; Kröger-Koch, C.; Dannenberger, D.; Tuchscherer, A.; Tröscher, A.; Trevisi, E.; Stefaniak, T.; Jawor, P.; Starke, S.; Mielenz, M.; Bachmann, L.; Hammon, H. M. (2020):
Changes in fatty acids in plasma and association with the inflammatory response in dairy cows abomasally infused with essential fatty acids and conjugated linoleic acid during late and early lactation. J Dairy Sci 103 (12): 11889-11910
https://doi.org/10.3168/jds.2020-18735
Vogel, L.; Gnott, M.; Kröger-Koch, C.; Dannenberger, D.; Tuchscherer, A.; Tröscher, A.; Kienberger, H.; Rychlik, M.; Starke, S.; Bachmann, L.; Hammon, H. M. (2020):
Effects of abomasal infusion of essential fatty acids together with conjugated linoleic acid in late and early lactation on performance, milk and body composition, and plasma metabolites in dairy cows. J Dairy Sci 103 (8): 7431-7450
https://doi.org/10.3168/jds.2019-18065
Liermann, W.; Viergutz, T.; Uken, K. L.; Vogel, L.; Gnott, M.; Dannenberger, D.; Tuchscherer, A.; Kienberger, H.; Rychlik, M.; Tröscher, A.; Hammon, H. M. (2020):
Influences of maternal conjugated linoleic acid and essential fatty acid supply during late pregnancy and early lactation on T and B cell subsets in mesenteric lymph nodes and the small intestine of neonatal calves. Front Vet Sci 7: 604452, 1-8
https://doi.org/10.3389/fvets.2020.604452
Kruse, M.; Kemper, M.; Gancheva, S.; Osterhoff, M.; Dannenberger, D.; Markgraf, D.F.; Machmann, J.; Hierholzer, J.; Roden, M.; Pfeiffer, H. (2020):
Dietary rapeseed oil supplementation reduces hepatic steatosis in obese men - A randomized controlled trial. Mol Nutr Food Res 64 (21): 2000419, 1-13
https://doi.org/10.1002/mnfr.202000419
Schindler, M.; Dannenberger, D.; Nuernberg, G.; Pendzialek, S.; Grybel, K.; Seeling, T.; Santos, A. (2020):
Embryonic fatty acid metabolism in diabetic pregnancy: the difference between embryoblasts and trophoblasts. Mol Hum Reprod 26 (11): 837-849
https://doi.org/10.1093/molehr/gaaa063
Dahl, N.; Albrecht, E.; Dannenberger, D.; Uken, K. L.; Hammon, H. M.; Maak, S. (2020):
Consequences of maternal essential fatty acid and conjugated linoleic acid supplementation on the development of calf muscle and adipose tissue. Animals-Basel 10 (9): 1598, 1-18
https://doi.org/10.3390/ani10091598
Dannenberger, D.; Möller, R.; Westphal, L.; Moritz, T.; Dähne, M.; Grunow, B. (2020):
Fatty acid composition in blubber, liver, and muscle of marine mammals in the southern Baltic Sea. Animals-Basel 10: 1509, 1-12
https://doi.org/10.3390/ani10091509
Suchý, T.; Zieschang, C.; Popkova, Y.; Kaczmarek, I.; Weiner, J.; Liebing, A. D.; Çakir, M. V.; Landgraf, K.; Gericke, M.; Pospisilik, J. A.; Körner, A.; Heiker, J. K.; Dannenberger, D.; Schiller, J.; Schöneberg, T.; Liebscher, V.; Thor, D. (2020):
The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance. Int J Obesity 44: 2124-2136
https://doi.org/10.1038/s41366-020-0570-2
Engel, K. M.; Dzyuba, B.; Ninhaus-Silveira, A.; Verissomo-Silveira, R.; Dannenberger, D.; Schiller, J.; Steinbach, C.; Dzyuba, B. (2020):
Sperm lipid composition in early diverged fish species: Internal vs. external mode of fertilization. Biomolecules 10 (2): 172, 1-25
https://doi.org/10.3390/biom10020172
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
Vijay Simha Baddela,
Volker Röttgen,
Andreas Vernunft,
Dirk Dannenberger,
Harald Michael Hammon,
Jens Vanselow
https://doi.org/10.3389/fendo.2020.00087
Popkova, Y.; Dannenberger, D.; Schiller, J.; Engel, K. M. (2019):
Differences in the lipid pattern during maturation of 3T3-L1 adipocytes investiged by thin-layer chromatography, gas chromatography, and mass spectrometric approaches. Anal Bioanal Chem 412: 2273-2249
https://doi.org/10.1007/s00216-019-02243-w
Stehr, M.; Grashorn, M.; Dannenberger, D.; Tuchscherer, A.; Gauly, M.; Metges, C. C.; Daş, G. (2019):
Resistance and tolerance to mixed nematode infections in relation to performance level in laying hens. Vet Parasitol 275: 108925, 1-12
https://doi.org/10.1016/j.vetpar.2019.108925
Möller, R.; Nürnberg, G.; Albrecht, E.; Ruth, W.; Brockmann, G. A.; Dannenberger, D. (2019):
A method for analyzing fatty acids in cattle hair, with special emphasis on lauric and myristic acid. Eur J Lipid Sci Tech 121 (11): 1900143, 1-7
https://doi.org/10.1002/ejlt.201900143
Liebig, M.; Dannenberger, D.; Vollmar, B.; Abshagen, K. (2019):
n-3 PUFAs reduce tumor load and improve survival in a NASH-tumor mouse model. Ther Adv Chronic Dis 10: 2040622319872118, 1-16
https://doi.org/10.1177/2040622319872118
Engel, K. M.; Sampels, S.; Dzyuba, B.; Podhorec, P.; Policar, T.; Dannenberger, D.; Schiller, J. (2019):
Swimming at different temperatures: The lipid composition of sperm from three freshwater fish species determined by mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Phys Lipids 221: 65-72
https://doi.org/10.1016/j.chemphyslip.2019.03.014
Liebig, M.; Dannenberger, D.; Vollmar, B.; Abshagen, K. (2019):
Endogenously increased n-3 PUFA levels in fat-1 transgenic mice do not protect from non-alcoholic steatohepatitis. Hepatobil Surg Nutr 8 (5): 447-458
https://doi.org/10.21037/hbsn.2019.04.03
Liu, Y; Albrecht, E.; Dannenberger, D.; Hammon, H. M.; Kühn, C.; Sauerwein, H.; Yang, R; Zhao, Z; Maak, S. (2019):
Retinol binding protein 4 abundance in plasma and tissues is related to body fat deposition in cattle. Sci Rep-UK 9: 8056, 1-13
https://doi.org/10.1038/s41598-019-44508-4
Schiavon, S.; Cecchinato, A.; Pegolo, S.; Dannenberger, D.; Tagliapietra, F.; Bittante, G. (2019):
Dose response of rumen-protected conjugated linoleic acid supplementation to fattening bulls and heifers on growth, and carcass and meat quality. J Anim Physiol An N 103: 997-1005
https://doi.org/10.1111/jpn.13107
Sharma, A.; Baddela, V. S.; Becker, D.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
https://doi.org/10.1530/EC-19-0011
Möller, R.; Dannenberger, D.; Nürnberg, G.; Strucken, E.-M.; Brockmann, G. A. (2019):
Relationship between fatty acid profile of hair and energy availability of lactating primiparous cows. J Dairy Res 86 (1): 77-84
https://doi.org/10.1017/S0022029918000791