Dr. rer. nat. Claudia Kalbe

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Zellphysiologie und Reproduktion
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Ontogenetische Entwicklung der Skelettmuskulatur in Nutztieren
  • Myogene und lipogene Prozesse
  • Myogene Vorläuferzellen

Lebenslauf

  • 2002-heute: Wissenschaftlerin am Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf, Institut für Muskelbiologie und Wachstum
  • 2006-2007: Elternzeit
  • 1999-2001: Postdoc an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 2000: Promotion zum Dr. rer. nat. an der Universität Rostock
  • 1995-1999: Promotionsstudium am Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf, Forschungsbereich Molekularbiologie
  • 1990-1995: Studium der Biologie an der Universität Rostock

Lehre

  • Seit 2013: Vorlesung/Praktikum Molekulare Tierzucht, Muskelentwicklung beim Nutztier, Mathematisch Naturwissenschaftliche Fakultät der Univerität Rostock (M.Sc.)
  • Seit 2004: Vorlesung Kleintierzucht an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock (M.Sc.)
  • 2000-2001: Praktikum: Moderne genetische Methoden in der Tierzucht, an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock
  • 1999-2001: Vorlesung Kleintierzucht an der Agrar- und Umweltwissenschaftlichen Fakultät der Universität Rostock

Publikationen

Kalbe, C.; Metzger, K.; Gariépy, C.; Palin, M. F. (2023):
Effect of muscle fibre types and carnosine levels on the expression of carnosine-related genes in pig skeletal muscle. Histochem Cell Biol 160: 63-77
https://doi.org/10.1007/s00418-023-02193-6
Schwerdtfeger, J.; Krause, A.; Kalbe, C.; Mazzuoli-Weber, G.; Eggert, A.; Puppe, B.; Kuhla, B.; Röttgen, V. (2023):
Endocannabinoid administration affects taste preference and the expression of cannabinoid and opioid receptors in the amygdala of early lactating cows. Sci Rep-UK 13: 4967, 1-13
https://doi.org/10.1038/s41598-023-31724-3
Metzger, K.; Kalbe, C.; Siengdee, P.; Ponsuksili, S. (2022):
The effects of temperature and donor piglet age on the transcriptomic profile and energy metabolism of myoblasts. Front Physiol 13: 979283, 1-13
https://doi.org/10.3389/fphys.2022.979283
Dannenberger, D.; Eggert, A.; Kalbe, C.; Woitalla, A.; Schwudke, D. (2022):
Are n-3 PUFAs from microalgae incorporated into membrane and storage lipids in pig muscle tissue? - A lipidomic approach. ACS Omega 7 (28): 24785-24794
https://doi.org/10.1021/acsomega.2c02476
Geng, R.; Knoll, J.; Harland, N.; Amend, B.; Enderle, M.; Linzenbold, W.; Abruzzese, T.; Kalbe, C.; Kemter, J.; Wolf, E.; Schenk, M.; Stenzl, A.; Aicher, W. (2022):
Replacing Needle Injection by a Novel Waterjet Technology Grants Improved Muscle Cell Delivery in Target Tissues. Cell Transplant 31: 1-17
https://doi.org/10.1177/09636897221080943
Metzger, K.; Dannenberger, D.; Tuchscherer, A.; Ponsuksili, S.; Kalbe, C. (2021):
Effects of temperature on proliferation of myoblasts from donor piglets with different thermoregulatory maturities. BMC Mol Cell Biol 22: 36, 1-15
https://doi.org/10.1186/s12860-021-00376-4
Palin, M. F.; Lapointe, J.; Gariépy, C.; Beaudry, D.; Kalbe, C. (2020):
Characterisation of intracellular molecular mechanisms modulated by carnosine in porcine myoblasts under basal and oxidative stress conditions. Plos One 15 (9): e0239496, 1-25
https://doi.org/10.1371/journal.pone.0239496
Metzger, K.; Tuchscherer, A.; Palin, M. F.; Ponsuksili, S.; Kalbe, C. (2020):
Establishment and validation of cell pools using primary muscle cells derived from satellite cells of pig skeletal muscle. IN VITRO CELL DEV-AN 56: 193-199
https://doi.org/10.1007/s11626-019-00428-2
Sciascia, Q. L.; Daş, G.; Maak, S.; Kalbe, C.; Metzler-Zebeli, B.; Metges, C. C. (2019):
Transcript profile of skeletal muscle lipid metabolism genes affected by diet in a piglet model of low birth weight. Plos One 14 (10): e0224484, 1-18
https://doi.org/10.1371/journal.pone.0224484
Sajjanar, B.; Siengdee, P.; Trakooljul, N.; Liu, X; Kalbe, C.; Wimmers, K.; Ponsuksili, S. (2019):
Cross-talk between energy metabolism and epigenetics during temperature stress response in C2C12 myoblasts. Int J Hyperther 36 (1): 776-784
https://doi.org/10.1080/02656736.2019.1639834
Zitnan, R.; Albrecht, E.; Kalbe, C.; Miersch, C.; Revajova, V.; Levkut, M.; Röntgen, M. (2019):
Muscle characteristics in chicks challenged with Salmonella Enteritidis and the effect of preventive application of the probiotic Enterococcus faecium. Poultry Sci 98 (5): 2014-2025
https://doi.org/10.3382/ps/pey561
Kalbe, C.; Priepke, A.; Nürnberg, G.; Dannenberger, D. (2019):
Effects of long-term microalgae supplementation on muscle microstructure, meat quality, and fatty acid composition in growing pigs. J Anim Physiol An N 103 (2): 574-582
https://doi.org/10.1111/jpn.13037
Kalbe, C.; Zebunke, M.; Lösel, Dorothea; Brendle, J.; Hoy, St.; Puppe, B. (2018):
Voluntary locomotor activity promotes myogenic growth potential in domestic pigs. Sci Rep-UK 8: 2533, 1-11
https://doi.org/10.1038/s41598-018-20652-2
Kalbe, C.; Lösel, D.; Block, J.; Lefaucheur, L.; Brüssow, K.-P.; Bellmann, O.; Pfuhl, R.; Puppe, B.; Otten, W.; Metges, C. C.; Rehfeldt, C. (2017):
Moderate high or low maternal protein diets change gene expression but not the phenotype of skeletal muscle from porcine fetuses. DOMEST ANIM ENDOCRIN 58: 63-75
https://dx.doi.org/10.1016/j.domaniend.2016.08.003
Goursot, C.; Düpjan, S.; Kalbe, C.; Kanitz, E.; Puppe, B.; Tuchscherer, A.; Leliveld, L. M. C. (2016):
Untersuchung der motorischen Lateralität beim Hausschwein (Sus scrofa). In: Aktuelle Arbeiten zur artgemäßen Tierhaltung 2016 (KTBL-Schrift , 511) KTBL, Darmstadt (978-3-945088-25-8): 273-275
Farmer, C.; Robertson, P.; Xiao, C. W.; Rehfeldt, C.; Kalbe, C. (2016):
Exogenous genistein in late gestation: effects on fetal development and sow and piglet performance. Animal 10 (9): 1423-1430
https://dx.doi.org/10.1017/S1751731116000355
Will, K.; Schering, L.; Albrecht, E.; Kalbe, C.; Maak, S. (2015):
Differentiation of bovine satellite cell-derived myoblasts under different culture conditions. IN VITRO CELL DEV-AN 51 (9): 885-889
https://dx.doi.org/10.1007/s11626-015-9916-9
Farmer, C.; Palin, M.-F.; Lösel, D.; Rehfeldt, C.; Kalbe, C. (2015):
Impact of diet deprivation and subsequent over-allowance of gestating sows on mammary gland and skeletal muscle development of their offspring at puberty. LIVEST SCI 175: 113-120
https://dx.doi.org/10.1016/j.livsci.2015.02.006
Paredes, S. P.; Kalbe, C.; Jansman, A. J. M.; Verstegen, M. W. A.; van Hees, H. M. J.; Lösel, D.; Gerrits, W. J. J.; Rehfeldt, C. (2013):
Predicted high-performing piglets exhibit more and larger skeletal muscle fibers. J Anim Sci 91 (12): 5589-5598
https://dx.doi.org/10.2527/jas.2013-6908
Will, K.; Kuzinski, J.; Kalbe, C.; Palin, M. F.; Rehfeldt, C. (2013):
Effects of leptin and adiponectin on the growth of porcine myoblasts are associated with changes in p44/42 MAPK signaling. DOMEST ANIM ENDOCRIN 45 (4): 196-205
https://dx.doi.org/10.1016/j.domaniend.2013.09.002