PD Dr. rer. nat. habil. Bianka Grunow
Forschungsinteressen
- Implementierung und Weiterentwicklung der 3R-Prinzipien (Replace, Reduce, Refine) in der Fischforschung Etablierung und Charakterisierung von Fisch-Zellkulturmodellen für grundlagen- und angewandte Fragestellungen, einschließlich zellulärer Differenzierungen sowie der Nutzung von 2D- und 3D-Kultursystemen
- Analyse von Toxizitäten und zellulären Stressreaktionen sowie Untersuchung physiologischer Anpassungsmechanismen von Fischen an klimabedingte Umweltveränderungen
- Untersuchung der Embryonal- und Larvalentwicklung von Fischen
- Förderung und Bewertung des Tierwohls in der Aquakultur
Publikationen
Koch, A.-K.; Grunow, B.; Moritz, T. (2025):
Recommendations for scientific fish husbandry: Scyliorhinus canicula (Carcharhiniformes, Scyliorhinidae).
Bulletin of Fish Biology 21: 1-17
Di Leonardo, V.; Brenmoehl, J.; Wanka, H.; Grunow, B. (2025):
Proliferation and metabolism of the Atlantic sturgeon cell line AOXlar7y under reduced serum concentration and growth factor stimulation.
Frontiers in Toxicology 7: 1636776
https://doi.org/10.3389/ftox.2025.1636776
Franz, G. P.; Stüeken, M.; Höhne, C.; Grunow, B. (2025):
Overlap of vertebral development and first gradings during pikeperch (Sander lucioperca) rearing: implications for possible temporal protocol adaptations.
Aquaculture International 33: 522
https://doi.org/10.1007/s10499-025-02208-0
Grunow, B.; Di Leonardo, V.; Tönißen, K. (2025):
Towards Animal-Free Toxicology: Establishment of Two Larval Brown Trout Cell Lines for Environmental Risk Assessment.
Toxics 13 (8): 696
https://doi.org/10.3390/toxics13080696
Tönißen, K.; Brenmoehl, J.; Wanka H.; Grunow, B. (2025):
Morphological and Metabolic Adaptations to Increasing Temperature: Insights from the In Vitro Model of Maraena Whitefish.
Fishes 10 (7): 352
https://doi.org/10.3390/fishes10070352
Tönißen, K.; Franz, G. P.; Albrecht, E.; Lutz, P.; Bochert, R.; Grunow, B. (2024):
Pikeperch muscle tissues: a comparative study of structure, enzymes, genes, and proteins in wild and farmed fish
Fish Physiology Biochemisty: 1-18
https://doi.org/10.1007/s10695-024-01354-1
Tönißen, K.; Franz, G. P.; Rebl, A.; Lutze, P.; Grunow, B. (2024):
Does Size Matter? Small and Large Larvae of Pikeperch (Sander lucioperca) in a Comparative Gene Expression Analysis
Fishes 9 (1): 33, 1-14
https://doi.org/10.3390/fishes9010033
Lutze, P.; Brenmoehl, J.; Tesenvitz, S.; Ohde, D.; Wanka, H.; Meyer, Z.; Grunow, B. (2024):
Effects of Temperature Adaptation on the Metabolism and Physiological Properties of Sturgeon Fish Larvae Cell Line
Cells 13: 269, 1-16
https://doi.org/10.3390/cells13030269
Kaya, Y.; Tönißen, K.; Verleih, M.; Rebl, H.; Grunow, B. (2023):
Establishment of an in vitro model from the vulnerable fish species Coregonus maraena (maraena whitefish): Optimization of growth conditions and characterization of the cell line. CELL BIOL INT
47 (3): 548-559
Grunow, B.; Di Leonardo, V. (2023):
In vitro Contracting Cardiomyogenic Models from Whole Fish Embryos and Larvae – Method, Properties, and Applications. In: Technologies in Cell Culture - A Journey From Basics to Advanced Applications
IntechOpen, Wien, Österreich (978-1-83969-445-5): 1-20 (Miroslav Blumenberg; Hrsg.)
https://doi.org/10.5772/intechopen.113858
Ripley, D. M.; Garner, T.; Hook, S.; Verissimo, A.; Grunow, B.; Moritz, T.; Clayton, P.; Shiels, H.; Stevens, A. (2023):
Warming during embryogenesis induces a lasting transcriptomic signature in fishes. Sci Total Environ 902: 165954, 1-11
Moritz, T.; Walter, J.; Grunow, B.; Thieme, P. (2023):
A true caudal fin or not? New insights in the evolution of the gadiform caudal fin. ZOOL J LINN SOC-LOND
199 (1): 26-44
Bochert, R.; Bernolle, D.; Grunow, B. (2023):
Comparison of fatty acid composition of the eggs of wild and farmed Coregonus maraena and the influence of feed. Fish Aquat Life
31: 1-14
Grunow, B.; Strauch, S. M. (2023):
Status assessment and opportunities for improving fish welfare in animal experimental research according to the 3R-Guidelines
REV FISH BIOL FISHER
Grunow, B. (2022):
Die Anwendung der 3R-Grundsätze (Reduction, Refinement und Replacement von Tierversuchen) in der Fischforschung und insbesondere der Aquakultur
Universität Greifswald, Greifswald: 1-250
Franz, G. P.; Tönißen, K.; Rebl, A.; Lutze, P.; Grunow, B. (2022):
The expression of myogenic gene markers during the embryo-larval-transition in Pikeperch (Sander lucioperca). AQUAC RES 53 (13): 4767-4781
Grunow, B.; Reismann, T.; Moritz, T. (2022):
Pre-Hatching Ontogenetic Changes of Morphological Characters of Small-Spotted Catshark (Scyliorhinus canicula). FISHES-BASEL 7 (3): 100, 1-11
https://doi.org/10.3390/fishes7030100
Franz, G. P.; Warth, P.; Grunow, B.; Konstantinidis, P. (2022):
Osteology of the White Barracudina, Arctozenus risso (Bonaparte) (Aulopiformes: Paralepididae). Ichthyology & Herpetology 110 (1): 115-130
https://doi.org/10.1643/i2020130
Tönißen, K.; Pfuhl, R.; Franz, G. P.; Dannenberger, D.; Bochert, R.; Grunow, B. (2022):
Impact of spawning season on fillet quality of wild pikeperch (Sander lucioperca). EUR FOOD RES TECHNOL 248: 1-9
https://doi.org/10.1007/s00217-022-03963-7
Grunow, B.; Franz, G. P.; Tönißen, K. (2021):
In Vitro Fish Models for the Analysis of Exotoxins and Temperature Increase in the Context of Global Warming. TOXICS 9 (11): 286, 1-15
https://doi.org/10.3390/toxics9110286