PD Dr. rer. nat. habil. Bianka Grunow
Forschungsinstitut für Nutztierbiologie (FBN)
Leiterin der Arbeitsgruppe Wachstumsphysiologie der Fische
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Leiterin der Arbeitsgruppe Wachstumsphysiologie der Fische
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Implementierung und Weiterentwicklung der 3R-Prinzipien (Replace, Reduce, Refine) in der Fischforschung Etablierung und Charakterisierung von Fisch-Zellkulturmodellen für grundlagen- und angewandte Fragestellungen, einschließlich zellulärer Differenzierungen sowie der Nutzung von 2D- und 3D-Kultursystemen
- Analyse von Toxizitäten und zellulären Stressreaktionen sowie Untersuchung physiologischer Anpassungsmechanismen von Fischen an klimabedingte Umweltveränderungen
- Untersuchung der Embryonal- und Larvalentwicklung von Fischen
- Förderung und Bewertung des Tierwohls in der Aquakultur
Publikationen
Di Leonardo, V.; Tönißen, K.; Brenmoehl, J.; Ohde, D.; Wanka, H.; Benning, K.; Grunow, B. (2025):
Sibling-derived cell lines of whole larval Siberian sturgeon as an in vitro model system for studying inter-individual differences within the same genomic heritage
Cells 14 (24): 2004, 1-15
https://doi.org/10.3390/cells14242004
Fischbach, V.; Franz, G.; Moritz, T.; Ohde, D.; Thieme, P.; Kotterba, P.; Polte, P.; Grunow, B. (2025):
Growth and developmental processes alternate during larval development of Atlantic herring
Evolution and Development 27 (4): e70022, 1-20
https://doi.org/10.1111/ede.70022
Koch, A.-K.; Grunow, B.; Moritz, T. (2025):
Recommendations for scientific fish husbandry: Scyliorhinus canicula (Carcharhiniformes, Scyliorhinidae)
Bulletin of Fish Biology 21: 1-17
Di Leonardo, V.; Brenmoehl, J.; Wanka, H.; Grunow, B. (2025):
Proliferation and metabolism of the Atlantic sturgeon cell line AOXlar7y under reduced serum concentration and growth factor stimulation
Frontiers in Toxicology 7: 1636776, 1-17
https://doi.org/10.3389/ftox.2025.1636776
Franz, G. P.; Stüeken, M.; Höhne, C.; Grunow, B. (2025):
Overlap of vertebral development and first gradings during pikeperch (Sander lucioperca) rearing: implications for possible temporal protocol adaptations
Aquaculture International 33: 522, 1-10
https://doi.org/10.1007/s10499-025-02208-0
Grunow, B.; Di Leonardo, V.; Tönißen, K. (2025):
Towards Animal-Free Toxicology: Establishment of Two Larval Brown Trout Cell Lines for Environmental Risk Assessment
Toxics 13 (8): 696, 1-18
https://doi.org/10.3390/toxics13080696
Tönißen, K.; Brenmoehl, J.; Wanka H.; Grunow, B. (2025):
Morphological and Metabolic Adaptations to Increasing Temperature: Insights from the In Vitro Model of Maraena Whitefish
Fishes 10 (7): 352, 1-18
https://doi.org/10.3390/fishes10070352
Moritz, T.; Bierbach, D.; Schwarzer J.; Grunow, B. (2024):
Recommendations for scientific fish husbandry – a series for promoting animal welfare, reproducibility and transferability in ichthyologic research
Bulletin of Fish Biology 20: 35-48
Tönißen, K.; Franz, G. P.; Albrecht, E.; Lutz, P.; Bochert, R.; Grunow, B. (2024):
Pikeperch muscle tissues: a comparative study of structure, enzymes, genes, and proteins in wild and farmed fish
Fish Physiology Biochemisty 50: 1527–1544
https://doi.org/10.1007/s10695-024-01354-1
Tönißen, K.; Franz, G. P.; Rebl, A.; Lutze, P.; Grunow, B. (2024):
Does Size Matter? Small and Large Larvae of Pikeperch (Sander lucioperca) in a Comparative Gene Expression Analysis
Fishes 9 (1): 33, 1-14
https://doi.org/10.3390/fishes9010033
Lutze, P.; Brenmoehl, J.; Tesenvitz, S.; Ohde, D.; Wanka, H.; Meyer, Z.; Grunow, B. (2024):
Effects of Temperature Adaptation on the Metabolism and Physiological Properties of Sturgeon Fish Larvae Cell Line
Cells 13 (3): 269, 1-16
https://doi.org/10.3390/cells13030269
Kaya, Y.; Tönißen, K.; Verleih, M.; Rebl, H.; Grunow, B. (2023):
Establishment of an in vitro model from the vulnerable fish species Coregonus maraena (maraena whitefish): Optimization of growth conditions and characterization of the cell line
Cell Biology International 47 (3): 548-559
https://doi.org/10.1002/cbin.11956
Ripley, D. M.; Garner, T.; Hook, S.; Verissimo, A.; Grunow, B.; Moritz, T.; Clayton, P.; Shiels, H.; Stevens, A. (2023):
Warming during embryogenesis induces a lasting transcriptomic signature in fishes
Science of The Total Environment 902: 165954, 1-11
https://doi.org/10.1016/j.scitotenv.2023.165954
Moritz, T.; Walter, J.; Grunow, B.; Thieme, P. (2023):
A true caudal fin or not? New insights in the evolution of the gadiform caudal fin
Zoological Journal of the Linnean Society 199 (1): 26-44
https://doi.org/10.1093/zoolinnean/zlad017
Bochert, R.; Bernolle, D.; Grunow, B. (2023):
Comparison of fatty acid composition of the eggs of wild and farmed Coregonus maraena and the influence of feed
Fisheries and Aquatic Life 31: 1-14
https://doi.org/10.2478/aopf-2023-0001
Grunow, B.; Strauch, S. M. (2023):
Status assessment and opportunities for improving fish welfare in animal experimental research according to the 3R-Guidelines
Reviews in Fish Biology and Fisheries 33: 1075–1093
https://doi.org/10.1007/s11160-023-09781-8
Franz, G. P.; Tönißen, K.; Rebl, A.; Lutze, P.; Grunow, B. (2022):
The expression of myogenic gene markers during the embryo-larval-transition in Pikeperch (Sander lucioperca)
Aquaculture Research 53 (13): 4767-4781
https://doi.org/10.1111/are.15969
Grunow, B.; Reismann, T.; Moritz, T. (2022):
Pre-Hatching Ontogenetic Changes of Morphological Characters of Small-Spotted Catshark (Scyliorhinus canicula)
Fishes 7 (3): 100, 1-11
https://doi.org/10.3390/fishes7030100
Franz, G. P.; Warth, P.; Grunow, B.; Konstantinidis, P. (2022):
Osteology of the White Barracudina, Arctozenus risso (Bonaparte) (Aulopiformes: Paralepididae)
Ichthyology & Herpetology 110 (1): 115-130
https://doi.org/10.1643/i2020130
Tönißen, K.; Pfuhl, R.; Franz, G. P.; Dannenberger, D.; Bochert, R.; Grunow, B. (2022):
Impact of spawning season on fillet quality of wild pikeperch (Sander lucioperca)
European Food Research and Technology 248: 1277-1285
https://doi.org/10.1007/s00217-022-03963-7