Dr. rer. nat. habil. Beate Fuchs

+49 38208 68-852
Forschungsinstitut für Nutztierbiologie (FBN)
Servicegruppe Metabolom
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Regulation des Lipidstoffwechsels
  • Lipidomics, Metabolomics
  • Massenspektrometrie & Analytik (GC-MS/MS, MALDI-TOF-MS, TLC, HR-ESI-MS/MS)

Lebenslauf

  • 2017-heute Leiterin der Zentralen Servicegruppe - Metabolomics, Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2016 Habilitation (Dr. rer. nat. habil.) an der Medizinischen Fakultät Leipzig
  • 2016 Forschungsaufenthalt an der University of Pittsburgh, USA
  • 2009-2017 Arbeitsgruppenleiterin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2007-2009 Wissenschaftlerin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2006 Forschungsaufenthalt an der Strathclyde University in Glasgow, UK
  • 2004 Forschungsaufenthalt an der University of Louisville, Kentucky, USA
  • 2002-2006 Postgradualstudium Toxikologie, University Leipzig, Abschluss: Fachchemikerin für Toxikologie und Umweltschutz
  • 2002-2006 Postdoc am Interdisziplinären Zentrum für Klinische Forschung (IZKF) der Medizinischen Fakultät Leipzig ("NMR und MALDI-TOF-MS-Untersuchungen des Knorpelabbaus bei Rheumatischer Arthritis: Strukturaufklärung und klinisches Monitoring")
  • 1998-2001 Doktorandin am Leibniz-Institut für Polymerforschung Dresden (Thema: 19F-NMR-Untersuchungen an strahlenmodifizierten Fluorpolymeren)
  • 1996-1997 Stipendiatin der Carl-Duisberg-Gesellschaft und Praktikantin bei Bayer de México in Mexico-City
  • 1996 Diplomarbeit in der "Analytischen Chemie" an der TU Freiberg (Thema: 31C-NMR-Untersuchungen von strukturellen Änderungen mikrobiell behandelter Braunkohle)

Publikationen

Wegener, J.; Zschornig, K.; Onischke, K.; Fuchs, B.; Schiller, J.; Muller, K. (2013):
Conservation of honey bee (Apis mellifera) sperm phospholipids during storage in the bee queen - A TLC/MALDI-TOF MS study. Experimental Gerontology 48: 213-222
Eibisch, M.; Riemer, T.; Fuchs, B.; Schiller, J. (2013):
Differently saturated fatty acids can be differentiated by 31P NMR subsequent to derivatization with 2-chloro-4,4,5,5-tetramethyldioxaphospholane: a cautionary note. J. Agric. Food Chem. 61: 2696-2700
Nimptsch, A.; Fuchs, B.; Suss, R.; Zschornig, K.; Jakop, U.; Goritz, F.; Schiller, J.; Muller, K. (2013):
A simple method to identify ether lipids in spermatozoa samples by MALDI-TOF mass spectrometry. Anal. Bioanal. Chem. 405: 6675-6682
Fuchs, B. (2012):
Analysis of phospolipids and glycolipids by thin-layer chromatography-matrix-assisted laser desorption and ionization mass spectrometry. J Chromatogr A 1259: 62-73
Dinkla, S.; Wessels, K.; Verdurmen, W. P. R.; Tomelleri, C.; Cluitmans, J. C. A.; Fransen, J.; Fuchs, B.; Schiller, J.; Joosten, I.; Brock, R.; Bosman, G. J. C. G. M. (2012):
Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. Cell Death & Disease 3: e410
Fuchs, B.; Muller, K.; Paasch, U.; Schiller, J. (2012):
Lysophospholipids: potential markers of diseases and infertility? Mini Rev Med Chem 12: 74-86
Jakop, U.; Fuchs, B.; Rudiger, K.; Schiller, J.; Muller, K.; Schulze, M. (2012):
Screening of boar sperm for their resistance to storage at low temperatures. Reproduction in Domestic Animals 47: 7-7
Eibisch, M.; Fuchs, B.; Schiller, J.; Suss, R.; Teuber, K. (2011):
Analysis of Phospholipid Mixtures from Biological Tissues by Matrix-Assisted Laser Desorption and Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS): A Laboratory Experiment. Journal of Chemical Education 88: 503-507
Wu, J.; Teuber, K.; Eibisch, M.; Fuchs, B.; Schiller, J. (2011):
Chlorinated and brominated phosphatidylcholines are generated under the influence of the Fenton reagent at low pH-a MALDI-TOF MS study. Chem Phys Lipids 164: 1-8
Jakop, U.; Fuchs, B.; Rudiger, K.; Schulze, M.; Schiller, J.; Muller, K. (2011):
Different responses of cold-sensitive and -resistant boar sperm to Triton X-100 exposure. Reproduction in Domestic Animals 46: 20-20
Fuchs, B.; Suss, R.; Teuber, K.; Eibisch, M.; Schiller, J. (2011):
Lipid analysis by thin-layer chromatography--a review of the current state. J Chromatogr A 1218: 2754-2774
Fuchs, B.; Bresler, K.; Schiller, J. (2011):
Oxidative changes of lipids monitored by MALDI MS. Chem Phys Lipids 164: 782-795
Fuchs, B.; Schnapka-Hille, L.; Schiller, J.; Cross, M. A. (2011):
Oxygen and cytokine-dependent changes in choline phospholipid saturation in hematopoietic progenitor cells detected by MALDI-TOF mass spectrometry. Chem Phys Lipids 164: 636-642
Eibisch, M.; Zellmer, S.; Gebhardt, R.; Suss, R.; Fuchs, B.; Schiller, J. (2011):
Phosphatidylcholine dimers can be easily misinterpreted as cardiolipins in complex lipid mixtures: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of lipids from hepatocytes. Rapid Commun Mass Spectrom 25: 2619-2626
Loewenbruck, K. F.; Fuchs, B.; Hermann, A.; Brandt, M.; Werner, A.; Kirsch, M.; Schwarz, S.; Schwarz, J.; Schiller, J.; Storch, A. (2011):
Proton MR spectroscopy of neural stem cells: does the proton-NMR peak at 1.28 ppm function as a biomarker for cell type or state? Rejuvenation Res 14: 371-381
Bischoff, A.; Eibisch, M.; Fuchs, B.; Suss, R.; Schurenberg, M.; Suckau, D.; Schiller, J. (2011):
A Simple TLC-MALDI Method to Monitor Oxidation Products of Phosphatidylcholines and -Ethanolamines. Acta Chromatographica 23: 365-375
Renner, C.; Zemitzsch, N.; Fuchs, B.; Geiger, K. D.; Hermes, M.; Hengstler, J.; Gebhardt, R.; Meixensberger, J.; Gaunitz, F. (2010):
Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model. Mol Cancer 9: 2
Lessig, J.; Fuchs, B. (2010):
HOCl-mediated glycerophosphocholine and glycerophosphoethanolamine generation from plasmalogens in phospholipid mixtures. Lipids 45: 37-51
Dannenberger, D.; Suss, R.; Teuber, K.; Fuchs, B.; Nuernberg, K.; Schiller, J. (2010):
The intact muscle lipid composition of bulls: an investigation by MALDI-TOF MS and P-31 NMR. Chemistry and Physics of Lipids 163: 157-164
Galle, J.; Bader, A.; Hepp, P.; Grill, W.; Fuchs, B.; Kas, J. A.; Krinner, A.; Marquass, B.; Muller, K.; Schiller, J.; Schulz, R. M.; von Buttlar, M.; von der Burg, E.; Zscharnack, M.; Loffler, M. (2010):
Mesenchymal stem cells in cartilage repair: state of the art and methods to monitor cell growth, differentiation and cartilage regeneration. Curr. Med. Chem. 17: 2274-2291