Dr. rer. nat. habil. Beate Fuchs

+49 38208 68-852
Forschungsinstitut für Nutztierbiologie (FBN)
Servicegruppe Metabolom
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Regulation des Lipidstoffwechsels
  • Lipidomics, Metabolomics
  • Massenspektrometrie & Analytik (GC-MS/MS, MALDI-TOF-MS, TLC, HR-ESI-MS/MS)

Lebenslauf

  • 2017-heute Leiterin der Zentralen Servicegruppe - Metabolomics, Leibniz-Institut für Nutztierbiologie (FBN) Dummerstorf
  • 2016 Habilitation (Dr. rer. nat. habil.) an der Medizinischen Fakultät Leipzig
  • 2016 Forschungsaufenthalt an der University of Pittsburgh, USA
  • 2009-2017 Arbeitsgruppenleiterin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2007-2009 Wissenschaftlerin am Institut für Medizinische Physik und Biophysik der Medizinischen Fakultät Leipzig
  • 2006 Forschungsaufenthalt an der Strathclyde University in Glasgow, UK
  • 2004 Forschungsaufenthalt an der University of Louisville, Kentucky, USA
  • 2002-2006 Postgradualstudium Toxikologie, University Leipzig, Abschluss: Fachchemikerin für Toxikologie und Umweltschutz
  • 2002-2006 Postdoc am Interdisziplinären Zentrum für Klinische Forschung (IZKF) der Medizinischen Fakultät Leipzig ("NMR und MALDI-TOF-MS-Untersuchungen des Knorpelabbaus bei Rheumatischer Arthritis: Strukturaufklärung und klinisches Monitoring")
  • 1998-2001 Doktorandin am Leibniz-Institut für Polymerforschung Dresden (Thema: 19F-NMR-Untersuchungen an strahlenmodifizierten Fluorpolymeren)
  • 1996-1997 Stipendiatin der Carl-Duisberg-Gesellschaft und Praktikantin bei Bayer de México in Mexico-City
  • 1996 Diplomarbeit in der "Analytischen Chemie" an der TU Freiberg (Thema: 31C-NMR-Untersuchungen von strukturellen Änderungen mikrobiell behandelter Braunkohle)

Publikationen

Schilf, P.; Künstner, A.; Olbrich, M.; Waschina, S.; Fuchs, B.; Galuska, C. E.; Braun, A.; Neuschütz, K.; Seutter, M.; Bieber, K.; Hellberg, L.; Sina, C.; Laskay, T.; Rupp, J.; Ludwig, R.; Zillikens, D.; Busch, H.; Sadik, C. D.; Misa, H.; Ibrahim, S. M. (2022):
A Mitochondrial Polymorphism Alters Immune Cell Metabolism and Protects Mice from Skin Inflammation. Int J Mol Sci 22 (3): 1006, 1-22
https://doi.org/10.3390/ijms22031006
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Gille, B.; Galuska, C. E.; Fuchs, B.; Peleg, S. (2021):
Recent advances in studying age-associated lipids alterations and dietary interventions in mammals. Front Aging 2: 773795, 1-7
https://doi.org/10.3389/fragi.2021.773795
Wołczańska, A.; Christie, W. W.; Fuchs, B.; Galuska, C. E.; Kowalczyk, B.; Palusińska-Szysz, M. (2021):
Fatty acid composition and lipid profiles as chemotaxonomic markers of phytopathogenic fungi Puccinia malvacearum and P. glechomatis. FUNGAL BIOL-UK 125 (11): 869-878
https://doi.org/10.1016/j.funbio.2021.05.008
Engel, M.; Schiller, J.; Galuska, C.E.; Fuchs, B. (2021):
Phospholipases and Reactive Oxygen Species Derived Lipid Biomarkers in Healthy and Diseased Humans and Animals – A Focus on Lysophosphatidylcholine. Front Physiol 12: 732319,1-8
https://doi.org/10.3389/fphys.2021.732319
Beckmann, L.; Künstner, A.; Freschi, M. L.; Huber, K.; Stölting, I.; Ibrahim, S. M.; Misa, H.; Freitag, J.; Langan, E. A.; Matschl, U.; Galuska, C. E.; Fuchs, B.; Knobloch, J. K.; Busch, H.; Raasch, M.-L. (2021):
Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect. PHARMACOL RES 170: 105724, 1-14
https://doi.org/10.1016/j.phrs.2021.105724
Ditz, T.; Schnapka-Hille, L.; Noack, N.; Dorow, J.; Ceglarek, U.; Niederwieser, D.; Schiller, J.; Fuchs, B.; Cross, M. (2019):
Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation 105: 27-32
https://doi.org/10.1016/j.diff.2018.12.002
de Diego, I.; Peleg, S.; Fuchs, B. (2019):
The role of lipids in aging-related metabolic changes. Chem Phys Lipids 222: 59-69
https://doi.org/10.1016/j.chemphyslip.2019.05.005
Palusińska-Szysz, M.; Szuster-Ciesielska, A.; Janczarek, M.; Wdowiak-Wróbel, S.; Schiller, J.; Reszczyńska, E.; Gruszecki, W.; Fuchs, B. (2019):
Genetic diversity of Legionella pcs and pmt genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines. Pathog Dis 77: ftz065, 1-13
https://doi.org/10.1093/femspd/ftz065
Ditz, T.; Fuchs, B. (2018):
Determination of the phosphatidylcholine/lysophosphatidylcholine ratio in intact serum by matrix-assisted laser desorption/ionisation mass spectrometry with prior enzymatic albumin digestion. Lipids 53: 971-977
https://doi.org/10.1002/lipd.12106
Broniec, A.; Zadlo, A.; Pawlak, A.; Fuchs, B.; Klosinski, R.; Thompson, D.; Sarna, T. (2017):
Interaction of plasmenylcholine with free radicals in selected model systems. Free Radic Biol Med 106: 368-378
Dinkla, S.; van Eijk, L. T.; Fuchs, B.; Schiller, J.; Joosten, I.; Brock, R.; Pickkers, P.; Bosman, G. J. (2016):
Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane. BBA Clin 5: 186-192
Schroter, J.; Griesinger, H.; Reuss, E.; Schulz, M.; Riemer, T.; Suss, R.; Schiller, J.; Fuchs, B. (2016):
Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry. J. Chromatogr. 1439: 89-96
Fuchs, B. (2015):
Analytical methods for (oxidized) plasmalogens: Methodological aspects and applications. Free Radical Research 49: 599-617
Fuchs, B.; Popkova, Y.; Suss, R.; Schiller, J. (2015):
Separation of (Phospho)Lipids by Thin-Layer Chromatography. Instrumental Thin-Layer Chromatography 375-405
Angelini, R.; Vortmeier, G.; Corcelli, A.; Fuchs, B. (2014):
A fast method for the determination of the PC/LPC ratio in intact serum by MALDI-TOF MS: An easy-to-follow lipid biomarker of inflammation. Chemistry and Physics of Lipids 183: 169-175
Fuchs, B.; Schiller, J. (2014):
Glycosaminoglycan degradation by selected reactive oxygen species. Antioxid. Redox Signal. 21: 1044-1062
Palusinska-Szysz, M.; Kania, M.; Turska-Szewczuk, A.; Danikiewicz, W.; Russa, R.; Fuchs, B. (2014):
Identification of Unusual Phospholipid Fatty Acyl Compositions of Acanthamoeba castellanii. Plos One 9: e01243
Fuchs, B. (2014):
Mass spectrometry and inflammation--MS methods to study oxidation and enzyme-induced changes of phospholipids. Anal. Bioanal. Chem. 406: 1291-1306
Griesinger, H.; Fuchs, B.; Suss, R.; Matheis, K.; Schulz, M.; Schiller, J. (2014):
Stationary phase thickness determines the quality of thin-layer chromatography/matrix-assisted laser desorption and ionization mass spectra of lipids. Anal. Biochem. 451: 45-47