Dr. rer. nat. Alexander Rebl
Forschungsinteressen
- Aufklärung von immunologischen und stressphysiologischen Mechanismen, die zur Optimierung von Gesundheitskonzepten in der Aquakultur beitragen
- Erfassung der genombiologischen Unterschiede zwischen Individuen und Populationen etablierter und neuer Aquakulturfischarten in Hinblick auf Immunkompetenz und Performance
Lebenslauf
- 2014-heute: Wissenschaftler in der Arbeitsgruppe Fischgenetik am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf
- 2009-2014: Leiter der Nachwuchsgruppe Genetik der Krankheitsabwehr bei Fischen am FBN
- 2007-2009: Postdoc in der Abteilung Fischgenetik am FBN
- 2004-2007: Promotion im Bereich Molekularbiologie an der Universität Rostock
- 1999-2004: Biologie-Diplomstudium an der Universität Rostock
Publikationen
Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kühn, C.; Wimmers, K.; Goldammer, T. (2011):
Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses. In: Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses (Schwerin M. Editoren Heft 18: Seyfert, H-M, Viereck G, Hrsg.) BUK!, Kiel (0946-1981) (18): 39-41
Di Meo, G. P.; Goldammer, T.; Perucatti, A.; Genualdo, V.; Iannuzzi, A.; Incarnato, D.; Rebl, A.; Di Berardino, D.; Iannuzzi, L. (2011):
Extended cytogenetic maps of sheep chromosome 1 and their cattle and river buffalo homoeologues: comparison with the OAR1 RH map and human chromosomes 2, 3, 21 and 1q. Cytogenet Genome Res 133 (1): 16-24
https://dx.doi.org/10.1159/000323796
Rebl, A.; Köbis, J.; Fischer, K.; Takizawa, F.; Verleih, M.; Wimmers, K.; Goldammer, T. (2011):
MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after VHSV infection.. Fish Shellfish Immun 31 (6): 1041-1050
https://dx.doi.org/10.1016/j.fsi.2011.09.004
Rebl, A.; Rebl, H.; Liu, S.; Goldammer, T.; Seyfert, H.-M. (2011):
Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation. Dev Comp Immunol 35 (1): 81-87
https://dx.doi.org/10.1016/j.dci.2010.08.012
Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kotterba, G.; Anders, E.; Wimmers, K.; Goldammer, T. (2010):
Molecular characterization of PRR13 and its tissue-specific expression in rainbow trout (Oncorhynchus mykiss). Fish Physiol Biochem 36 (4): 1271-1276
https://dx.doi.org/10.1007/s10695-010-9407-6
Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T. (2009):
Cloning and tissue-specific expression of a delta-COP homologue in a freshwater and a brackish water-adapted strain of rainbow trout (Oncorhynchus mykiss). Genes Genet Syst 84 (3): 239-243
https://dx.doi.org/10.1266/ggs.84.239
Rebl, A.; Köllner, B.; Anders, E.; Wimmers, K.; Goldammer, T. (2009):
Peptidylarginine deiminase gene is differentially expressed in freshwater and brackish water rainbow trout. Mol Biol Rep 37 (5): 2333-2339
https://dx.doi.org/10.1007/s11033-009-9738-5
Goldammer, T.; Brunner, R. M.; Rebl, A.; Wu, Ch.; Nomura, K.; Hadfield, T.S.; Maddox, J.F.; Cockett, N. (2009):
Cytogenetic anchoring of radiation hybrid and virtual maps of sheep chromosome X and comparison of X chromosomes in sheep, cattle, and human. Chromosome Res 17 (4): 497-506
https://dx.doi.org/10.1007/s10577-009-9047-9
Goldammer, T.; Brunner, R. M.; Rebl, A.; Wu, Ch.; Nomura, K.; Gill, Clare A.; Hadfield, T.S.; Dalrymple, B.; Womack, J.E.; Cockett, N. (2009):
A high-resolution radiation hybrid map of sheep chromosome X and comparison with human and cattle. Cytogenet Genome Res 125 (1): 40-45
https://dx.doi.org/10.1159/000207520
Rebl, A.; Fischer, K.; Köllner, B.; Seyfert, H.-M. (2009):
Characterization of two key-factors of teleost Innate Immunity: MyD88 and Serum Amyloid A from rainbow trout. VET IMMUNOL IMMUNOP 131 (1-2): 122-126
https://dx.doi.org/10.1016/j.vetimm.2009.03.006
Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T. (2008):
Characterization of Dehydrodolichyl diphosphate synthase gene in rainbow trout (Oncorhynchus mykiss). Comp Biochem Biophys B 152 (3): 260-265
https://dx.doi.org/10.1016/j.cbpb.2008.12.003
Rebl, A.; Hoyheim, B.; Fischer, K.; Köllner, B.; Siegl, Edda; Seyfert, H.-M. (2008):
Tollip, a negative regulator of TLR-signalling, is encoded by twin genes in salmonid fish. Fish Shellfish Immun 25 (1-2): 153-162
https://dx.doi.org/10.1016/j.fsi.2008.04.002
Rebl, A.; Siegl, Edda; Köllner, B.; Fischer, K.; Seyfert, H.-M. (2007):
Characterization of twin toll-like receptors from rainbow trout (Oncorhynchus mykiss): Evolutionary relationship and induced expression by Aeromonas salmonicida salmonicida. Dev Comp Immunol 31 (5): 499-510
https://dx.doi.org/10.1016/j.dci.2006.08.007