Dr. rer. nat. Alexander Rebl

Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Fischgenetik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Forschungsinteressen

  • Aufklärung von immunologischen und stressphysiologischen Mechanismen, die zur Optimierung von Gesundheitskonzepten in der Aquakultur beitragen
  • Erfassung der genombiologischen Unterschiede zwischen Individuen und Populationen etablierter und neuer Aquakulturfischarten in Hinblick auf Immunkompetenz und Performance

Lebenslauf

  • 2014-heute: Wissenschaftler in der Arbeitsgruppe Fischgenetik am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf
  • 2009-2014: Leiter der Nachwuchsgruppe Genetik der Krankheitsabwehr bei Fischen am FBN
  • 2007-2009: Postdoc in der Abteilung Fischgenetik am FBN
  • 2004-2007: Promotion im Bereich Molekularbiologie an der Universität Rostock
  • 1999-2004: Biologie-Diplomstudium an der Universität Rostock

Publikationen

Sarais, F.; Rebl, H.; Verleih, M.; Ostermann, S.; Krasnov, A.; Köllner, B.; Goldammer, T.; Rebl, A. (2020):
Characterisation of the teleostean κB-Ras family: The two members NKIRAS1 and NKIRAS2 from rainbow trout influence the activity of NF-κB in opposite ways. Fish Shellfish Immun 106: 1004-1013
https://doi.org/10.1016/j.fsi.2020.08.052
Bornhöfft, K.; Martorell Ribera, J.; Viergutz, T.; Venuto, M. T.; Gimsa, U.; Galuska, S. P.; Rebl, A. (2020):
Characterization of sialic acid-binding immunoglobulin-type lectins in fish reveals teleost-specific structures and expression patterns. Cells-Basel 9 (4): 836, 1-19
https://doi.org/10.3390/cells9040836
Venuto, M. T.; Decloquement, M.; Martorell Ribera, J.; Noel, M.; Rebl, A.; Cogez, V.; Petit, D.; Galuska, S. P.; Harduin-Lepers, A. (2020):
Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective. Int J Mol Sci 21 (2): 513, 1-21
https://doi.org/10.3390/ijms21020513
Koll, R.; Martorell Ribera, J.; Brunner, R. M.; Rebl, A.; Goldammer, T. (2020):
Gene profiling in the adipose fin of salmonid fishes supports its function as a flow sensor. Genes-Basel 11 (1): 21, 1-22
https://doi.org/10.3390/genes11010021
Martorell Ribera, J.; Nipkow, M.; Viergutz, T.; Brunner, R. M.; Bochert, R.; Koll, R.; Goldammer, T.; Gimsa, U.; Rebl, A. (2020):
Early response of salmonid head-kidney cells to stress hormones and toll-like receptor ligands. Fish Shellfish Immun 98: 950-961
https://doi.org/10.1016/j.fsi.2019.11.058
Nguinkal, J. A.; Brunner, R. M.; Verleih, M.; Rebl, A.; de los Rios Pérez, L.; Schäfer, N.; Hadlich, F.; Stüeken, M.; Wittenburg, D.; Goldammer, T. (2019):
The first highly contiguous genome assembly of pikeperch (Sander lucioperca), an emerging aquaculture species in Europe. Genes-Basel 10: 708, 1-14
https://doi.org/10.3390/genes10090708
Borchel, A.; Verleih, M.; Kühn, C.; Rebl, A.; Goldammer, T. (2019):
Evolutionary expression differences of creatine synthesis-related genes: Implications for skeletal muscle metabolism in fish. Sci Rep-UK 9: 5429, 1-8
https://doi.org/10.1038/s41598-019-41907-6
Verleih, M.; Borchel, A.; Rebl, A.; Brenmoehl, J.; Kühn, C.; Goldammer, T. (2019):
A molecular survey of programmed cell death in rainbow trout: Structural and functional specifications of apoptotic key molecules. Comp Biochem Phys B 230: 57-69
https://doi.org/10.1016/j.cbpb.2019.01.012
Montero, R.; Strzelczyk, J.; Tze Ho Chan, J.; Verleih, M.; Rebl, A.; Goldammer, T.; Köllner, B.; Korytár, T. (2019):
Dawn to dusk: Diurnal rhythm of the immune response in rainbow trout (Oncorhynchus mykiss). BIOLOGY-BASEL 9 (1): 8, 1-13
https://doi.org/10.3390/biology9010008
Rebl, A.; Rebl, H.; Verleih, M.; Haupt, S.; Goldammer, T.; Seyfert, H.-M. (2019):
At least two genes encode many variants of Irak3 in rainbow trout, but neither the full-length factor nor its variants interfere directly with the TLR-mediated stimulation of inflammation. Front Immunol 10: 2246, 1-19
https://doi.org/10.3389/fimmu.2019.02246. eCollection 2019.
Bornhöfft, K.; Rebl, A.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P. (2019):
Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol 10: 2478, 1-15
https://doi.org/10.3389/fimmu.2019.02478
Swirplies, F.; Würtz, S.; Baßmann, B.; Orban, A.; Schäfer, N.; Brunner, R. M.; Hadlich, F.; Goldammer, T.; Rebl, A. (2019):
Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture 501: 260-271
https://doi.org/10.1016/j.aquaculture.2018.11.043
Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):
Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):
https://doi.org/10.1186/s13578-018-0262-y
Rebl, A.; Verleih, M.; Nipkow, M.; Altmann, S.; Bochert, R.; Goldammer, T. (2018):
Gradual and acute temperature rise induces crossing endocrine, metabolic, and immunological pathways in Maraena whitefish (Coregonus maraena). Front Genet 9: 241, 1-16
https://doi.org/10.3389/fgene.2018.00241
Nipkow, M.; Wirthgen, E.; Luft, P.; Rebl, A.; Hoeflich, A.; Goldammer, T. (2018):
Characterization of igf1 and igf2 genes during maraena whitefish (Coregonus maraena) ontogeny and the effect of temperature on embryogenesis and igf expression. Growth Horm IGF Res 40: 32-43
https://doi.org/10.1016/j.ghir.2018.04.003
Rebl, A.; Goldammer, T. (2018):
Under control: the innate immunity of fish from the inhibitors' perspective. Fish Shellfish Immun 77: 328-349
https://doi.org/doi: 10.1016/j.fsi.2018.04.016
Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):
Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10
https://doi.org/10.3390/ijms18061679
Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):
Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231
https://doi.org/10.1016/j.dci.2018.05.008
Borchel, A.; Komisarczuk, A.; Rebl, A.; Goldammer, T.; Nilsen, F. (2018):
Systematic identification and characterization of stress-inducible heat shock proteins (HSPs) in the salmon louse (Lepeophtheirus salmonis). CELL STRESS CHAPERON 23 (1): 127-139
https://doi.org/10.1007/s12192-017-0830-9
Wirthgen, E.; Hoeflich, A.; Rebl, A.; Günther, J. (2017):
Kynurenic acid: The Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions. Front Immunol 8: 1957, 1-13
https://dx.doi.org/10.3389/fimmu.2017.01957