Dr. rer. nat. Alexander Rebl
Forschungsinstitut für Nutztierbiologie (FBN)
Arbeitsgruppe Fischgenetik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Arbeitsgruppe Fischgenetik
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Forschungsinteressen
- Aufklärung von immunologischen und stressphysiologischen Mechanismen, die zur Optimierung von Gesundheitskonzepten in der Aquakultur beitragen
- Erfassung der genombiologischen Unterschiede zwischen Individuen und Populationen etablierter und neuer Aquakulturfischarten in Hinblick auf Immunkompetenz und Performance
Lebenslauf
- 2014-heute: Wissenschaftler in der Arbeitsgruppe Fischgenetik am Forschungsinstitut für Nutztierbiologie (FBN) Dummerstorf
- 2009-2014: Leiter der Nachwuchsgruppe Genetik der Krankheitsabwehr bei Fischen am FBN
- 2007-2009: Postdoc in der Abteilung Fischgenetik am FBN
- 2004-2007: Promotion im Bereich Molekularbiologie an der Universität Rostock
- 1999-2004: Biologie-Diplomstudium an der Universität Rostock
Publikationen
Martorell Ribera, J.; Venuto, M. T.; Otten, W.; Brunner, R. M.; Goldammer, T.; Rebl, A.; Gimsa, U. (2020):
Time-dependent effects of acute handling on the brain monoamine system of the Salmonid Coregonus maraena. FRONT NEUROSCI-SWITZ 14: 1293, 1-18
https://doi.org/10.3389/fnins.2020.591738
de los Rios Pérez, L.; Brunner, R. M.; Hadlich, F.; Rebl, A.; Kühn, C.; Wittenburg, D.; Goldammer, T.; Verleih, M. (2020):
Comparative analysis of the transcriptome and distribution of putative SNPs in two rainbow trout (Oncorhynchus mykiss) breeding strains by using next-generation sequencing. Genes-Basel 11: 841, 1-16
https://doi.org/10.3390/genes11080841
Venuto, M. T.; Martorell Ribera, J.; Bochert, R.; Harduin-Lepers, A; Rebl, A.; Galuska, S. P. (2020):
Characterization of the polysialylation status in ovaries of the salmonid fish Coregonus maraena and the percid fish Sander lucioperca. Cells-Basel 9 (11): 2391, 1-15
https://doi.org/10.3390/cells9112391
Rebl, A.; Korytár, T.; Borchel, A.; Bochert, R.; Strzelczyk, J.; Goldammer, T.; Verleih, M. (2020):
The synergistic interaction of thermal stress coupled with overstocking strongly modulates the transcriptomic activity and immune capacity of rainbow trout (Oncorhynchus mykiss). Sci Rep-UK 10: 14913, 1-15
https://doi.org/10.1038/s41598-020-71852-8
Krasnov, A.; Afanasyef, S.; Nyland, S.; Rebl, A. (2020):
Multigene expression assay for assessment of the immune status of Atlantic salmon. Genes-Basel 11 (11): 1236, 1-11
https://doi.org//10.3390/genes11111236
Sarais, F.; Rebl, H.; Verleih, M.; Ostermann, S.; Krasnov, A.; Köllner, B.; Goldammer, T.; Rebl, A. (2020):
Characterisation of the teleostean κB-Ras family: The two members NKIRAS1 and NKIRAS2 from rainbow trout influence the activity of NF-κB in opposite ways. Fish Shellfish Immun 106: 1004-1013
https://doi.org/10.1016/j.fsi.2020.08.052
Bornhöfft, K.; Martorell Ribera, J.; Viergutz, T.; Venuto, M. T.; Gimsa, U.; Galuska, S. P.; Rebl, A. (2020):
Characterization of sialic acid-binding immunoglobulin-type lectins in fish reveals teleost-specific structures and expression patterns. Cells-Basel 9 (4): 836, 1-19
https://doi.org/10.3390/cells9040836
Venuto, M. T.; Decloquement, M.; Martorell Ribera, J.; Noel, M.; Rebl, A.; Cogez, V.; Petit, D.; Galuska, S. P.; Harduin-Lepers, A. (2020):
Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective. Int J Mol Sci 21 (2): 513, 1-21
https://doi.org/10.3390/ijms21020513
Koll, R.; Martorell Ribera, J.; Brunner, R. M.; Rebl, A.; Goldammer, T. (2020):
Gene profiling in the adipose fin of salmonid fishes supports its function as a flow sensor. Genes-Basel 11 (1): 21, 1-22
https://doi.org/10.3390/genes11010021
Martorell Ribera, J.; Nipkow, M.; Viergutz, T.; Brunner, R. M.; Bochert, R.; Koll, R.; Goldammer, T.; Gimsa, U.; Rebl, A. (2020):
Early response of salmonid head-kidney cells to stress hormones and toll-like receptor ligands. Fish Shellfish Immun 98: 950-961
https://doi.org/10.1016/j.fsi.2019.11.058
Nguinkal, J. A.; Brunner, R. M.; Verleih, M.; Rebl, A.; de los Rios Pérez, L.; Schäfer, N.; Hadlich, F.; Stüeken, M.; Wittenburg, D.; Goldammer, T. (2019):
The first highly contiguous genome assembly of pikeperch (Sander lucioperca), an emerging aquaculture species in Europe. Genes-Basel 10: 708, 1-14
https://doi.org/10.3390/genes10090708
Borchel, A.; Verleih, M.; Kühn, C.; Rebl, A.; Goldammer, T. (2019):
Evolutionary expression differences of creatine synthesis-related genes: Implications for skeletal muscle metabolism in fish. Sci Rep-UK 9: 5429, 1-8
https://doi.org/10.1038/s41598-019-41907-6
Verleih, M.; Borchel, A.; Rebl, A.; Brenmoehl, J.; Kühn, C.; Goldammer, T. (2019):
A molecular survey of programmed cell death in rainbow trout: Structural and functional specifications of apoptotic key molecules. Comp Biochem Phys B 230: 57-69
https://doi.org/10.1016/j.cbpb.2019.01.012
Montero, R.; Strzelczyk, J.; Tze Ho Chan, J.; Verleih, M.; Rebl, A.; Goldammer, T.; Köllner, B.; Korytár, T. (2019):
Dawn to dusk: Diurnal rhythm of the immune response in rainbow trout (Oncorhynchus mykiss). BIOLOGY-BASEL 9 (1): 8, 1-13
https://doi.org/10.3390/biology9010008
Rebl, A.; Rebl, H.; Verleih, M.; Haupt, S.; Goldammer, T.; Seyfert, H.-M. (2019):
At least two genes encode many variants of Irak3 in rainbow trout, but neither the full-length factor nor its variants interfere directly with the TLR-mediated stimulation of inflammation. Front Immunol 10: 2246, 1-19
https://doi.org/10.3389/fimmu.2019.02246. eCollection 2019.
Bornhöfft, K.; Rebl, A.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P. (2019):
Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol 10: 2478, 1-15
https://doi.org/10.3389/fimmu.2019.02478
Swirplies, F.; Würtz, S.; Baßmann, B.; Orban, A.; Schäfer, N.; Brunner, R. M.; Hadlich, F.; Goldammer, T.; Rebl, A. (2019):
Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture 501: 260-271
https://doi.org/10.1016/j.aquaculture.2018.11.043
Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):
Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):
https://doi.org/10.1186/s13578-018-0262-y
Rebl, A.; Verleih, M.; Nipkow, M.; Altmann, S.; Bochert, R.; Goldammer, T. (2018):
Gradual and acute temperature rise induces crossing endocrine, metabolic, and immunological pathways in Maraena whitefish (Coregonus maraena). Front Genet 9: 241, 1-16
https://doi.org/10.3389/fgene.2018.00241
Nipkow, M.; Wirthgen, E.; Luft, P.; Rebl, A.; Hoeflich, A.; Goldammer, T. (2018):
Characterization of igf1 and igf2 genes during maraena whitefish (Coregonus maraena) ontogeny and the effect of temperature on embryogenesis and igf expression. Growth Horm IGF Res 40: 32-43
https://doi.org/10.1016/j.ghir.2018.04.003