As covalently attached modifications of lipids and proteins or as freestanding entities glycans (mono- and oligosaccharides) are involved in several biological processes like the modulation of cell-cell interactions during organogenesis. Our research team is prevalently interested in the physiological role of these glycoconjugates in the male and female reproductive tract. To evaluate in a reproductive context the impact of different glycoconjugates during immunological and interaction processes as well as during cellular differentiation, analytical techniques like HPLC and nanoLC-ESI-MS in addition to different cell culture and animal models are applied.
Furthermore, we develop novel strategies for in-depth characterization of glycolconjugates and are interested to combine these techniques with laser-microdissection applications (laser-supported cell isolation from microscopic regions) to analyze the glycome of defined cell types during physiological and pathophysiological conditions.
Dr. rer. nat. Juliane Günther
Institute of Reproductive Biology
+49 38208 68-781
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+49 38208 68-781 | ||||
Dr. biol. hom. Kristina Zlatina
Institute of Reproductive Biology
+49 38208 68-781
| E-Mail
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+49 38208 68-781 |
Franziska Kubelt
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Anna Steinmetz
Institute of Reproductive Biology
+49 38208 68-753
| E-Mail
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+49 38208 68-753 |