PD Dr. sc. agr. habil. Siriluck Wimmers
Research Institute for Farm Animal Biology (FBN)
Head of Working group Integrative Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of Working group Integrative Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Molecular genetics and expression of traits related to meat quality and other productive traits in livestock
- miRNA regulatory network involved in energy metabolism and meat quality in muscle cells
- Trait-associated variation at the molecular levels of the genotype-phenotype map
Curriculum Vitae
- Since 2014: Head of unit Functional Genome Analysis, Institute of Genome Biology, FBN
- 2004-2013: Senior Scientist, Functional Genome Analysis, FBN
- 2003: Habilitation, venia legendi Animal Breeding and Genetics, University of Bonn
- 1997-2003: Scientist at the Faculty of Agriculture, Rheinische Friedrich-Wilhelm-University Bonn
- 1997: Assisted Professor of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand
- 1990-1995: DAAD-Scholarship, Doctoral student at the Institute of Animal production, TU Berlin
- 1987-1997: Lecturer of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand
Teaching
Lectures and seminars at the Faculty of Agriculture, University of Bonn
Publications
Loan, H. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
Novel SNPs of the porcine TRIP12 are associated with water holding capacity of meat. Czech J Anim Sci 58 (11): 525-533
Siengdee, P.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2013):
Transcriptional profiling and miRNA-dependent regulatory network analysis of longissimus dorsi muscle during prenatal and adult stages in two distinct pig breeds. Anim Genet 44 (4): 398-407
https://dx.doi.org/10.1111/Age.12032
Adler, M.; Muràni, E.; Brunner, R. M.; Ponsuksili, S.; Wimmers, K. (2013):
Transcriptomic response of porcine PBMCs to vaccination with tetanus toxoid as a model antigen. Plos One 8 (3): 1-8
https://dx.doi.org/10.1371/journal.pone.0058306
Rangkasenee, N.; Muràni, E.; Brunner, R. M.; Schellander, K.; Cinar, M. U.; Luther, H.; Hofer, A.; Stoll, M.; Witten, A.; Ponsuksili, S.; Wimmers, K. (2013):
Genome-wide association identifies TBX5 as candidate gene for osteochondrosis providing a functional link to cartilage perfusion as initial factor. Front Genet 4: 78
https://dx.doi.org/10.3389/fgene.2013.00078
Ponsuksili, S.; Du, Y.; Hadlich, F.; Siengdee, P.; Muràni, E.; Schwerin, M.; Wimmers, K. (2013):
Correlated mRNAs and miRNAs from co-expression and regulatory networks affect porcine muscle and finally meat properties. BMC Genomics 14: 533-550
https://dx.doi.org/10.1186/1471-2164-14-533
Rangkasenee, N.; Muràni, E.; Schellander, K.; Cinar, M. U.; Ponsuksili, S.; Wimmers, K. (2013):
Gene expression profiling of articular cartilage reveals functional pathways and networks of candidate genes for osteochondrosis in pigs. Physiol Genomics 45 (18): 856-865
https://dx.doi.org/10.1152/physiolgenomics.00055.2013
Nossol, C.; Diesing, A.-K.; Kahlert, S.; Kersten, S.; Kluess, J.; Ponsuksili, S.; Hartig, R.; Wimmers, K.; Dänicke, S.; Rothkötter, H.-J. (2013):
Deoxynivalenol affects the composition of the basement membrane proteins and influences en route the migration of CD16+ cells into the intestinal epithelium. Mycotoxin Res 29 (4): 245-254
https://dx.doi.org/10.1007/s12550-013-0177-8
Heidt, H.; Cinar, M. U.; Uddin, M. J.; Looft, C.; Jüngst, H.; Tesfaye, D.; Becker, A.; Zimmer, A.; Ponsuksili, S.; Wimmers, K.; Tholen, E.; Schellander, K.; Grosse-Brinkhaus, C. (2013):
A genetical genomics approach reveals new candidates and confirms known candidate genes for drip loss in a porcine resource population. Mamm Genome 24 (9-10): 416-426
https://dx.doi.org/10.1007/s00335-013-9473-z
Adler, M.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
PBMC transcription profiles of pigs with divergent humoral immune responses and lean growth performance. Int J Biol Sci 9 (9): 907-916
https://dx.doi.org/10.1371/journal.pone.0076705
Huynh, L. T. P.; Muràni, E.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2013):
UBE3B and ZRANB1 polymorphisms and transcript abundance are associated with water holding capacity of porcine M. longissimus dorsi. Meat Sci 95 (2): 166-172
https://dx.doi.org/10.1016/j.meatsci.2013.04.033
Muràni, E.; Ponsuksili, S.; Reyer, H.; Wittenburg, D.; Wimmers, K. (2013):
Expression variation of the porcine ADRB2 has a complex genetic background. Mol Genet genomics 288 (11): 615-625
https://dx.doi.org/10.1007/s00438-013-0776-2
Reyer, H.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2013):
Transcript variants of the porcine glucocorticoid receptor gene (NR3C1). Gen Comp Endocr 189: 127-133
https://dx.doi.org/10.1016/j.ygcen.2013.04.038
Brenmoehl, J.; Walz, C.; Renne, U.; Ponsuksili, S.; Wolf, C.; Langhammer, M.; Schwerin, M.; Hoeflich, A. (2013):
Metabolic adaptations in the liver of born long-distance running mice. Med Sci Sport Exer 45 (5): 841-850
https://dx.doi.org/10.1249/MSS.0b013e31827e0fca
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2013):
Dietary protein restriction and excess of pregnant German Landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring. J Nutr Biochem 24 (2): 484-495
https://dx.doi.org/10.1016/j.jnutbio.2012.01.011
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
Association of TLR5 sequence variants and mRNA level with cytokine transcription in pigs. Immunogenetics 65 (2): 125-132
https://dx.doi.org/10.1007/s00251-012-0662-9
Rangkasenee, N.; Muràni, E.; Brunner, R. M.; Schellander, K.; Cinar, M. U.; Scholz, A. M.; Luther, H.; Hofer, A.; Ponsuksili, S.; Wimmers, K. (2013):
KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs. Mol Biol Rep 39 (4): 2859-2866
https://dx.doi.org/10.1007/s11033-012-2301-9
Chomwisarutkun, K.; Muràni, E.; Brunner, R. M.; Ponsuksili, S.; Wimmers, K. (2013):
QTL region-specific microarrays reveal differential expression of positional candidate genes of signaling pathways associated with the liability for the inverted teat defect. Anim Genet 44 (2): 139-148
https://dx.doi.org/10.1111/j.1365-2052.2012.02378.x
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Association of TLR4 polymorphism with cytokine expression level and pulmonary lesion score in pigs. Mol Biol Rep 39 (6): 7003-7009
https://dx.doi.org/10.1007/s11033-012-1530-2
Do, V. A. K.; Ponsuksili, S.; Muràni, E.; Huynh, L. T. P.; Brunner, R. M.; Wimmers, K. (2012):
Detection of a polymorphic site of the porcine C8G gene and evaluation of association with haemolytic complement activity. Arch Tierzucht 55 (3): 255-262
Ponsuksili, S.; Muràni, E.; Schwerin, M.; Schellander, K.; Tesfaye, D.; Wimmers, K. (2012):
Gene expression and DNA-methylation of bovine pretransfer endometrium depending on its receptivity after in vitro-produced embryo transfer. Plos One 7 (8): 1-13
https://dx.doi.org/10.1371/journal.pone.0042402