PD Dr. sc. agr. habil. Siriluck Wimmers
Research Institute for Farm Animal Biology (FBN)
Head of Working group Integrative Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of Working group Integrative Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Molecular genetics and expression of traits related to meat quality and other productive traits in livestock
- miRNA regulatory network involved in energy metabolism and meat quality in muscle cells
- Trait-associated variation at the molecular levels of the genotype-phenotype map
Curriculum Vitae
- Since 2014: Head of unit Functional Genome Analysis, Institute of Genome Biology, FBN
- 2004-2013: Senior Scientist, Functional Genome Analysis, FBN
- 2003: Habilitation, venia legendi Animal Breeding and Genetics, University of Bonn
- 1997-2003: Scientist at the Faculty of Agriculture, Rheinische Friedrich-Wilhelm-University Bonn
- 1997: Assisted Professor of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand
- 1990-1995: DAAD-Scholarship, Doctoral student at the Institute of Animal production, TU Berlin
- 1987-1997: Lecturer of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand
Teaching
Lectures and seminars at the Faculty of Agriculture, University of Bonn
Publications
Oster, M.; Gerlinger, Ch.; Heide, K.; Just, F.; Borgelt, L.; Wolf, C.; Polley, C.; Vollmar, B.; Muráni, E.; Ponsuksili, S.; Wimmers, K. (2018):
Lower dietary phosphorus supply in pigs match both animal welfare aspects and resource efficiency. Ambio 47 (Suppl. 1): 20-29
https://doi.org/10.1007/s13280-017-0969-8
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2017):
Genetic architecture and regulatory impact on hepatic microRNA expression linked to immune and metabolic traits. Open Biol 7 (11): 170101, 1-11
https://dx.doi.org/10.1098/rsob.170101
Liu, X; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
Mitochondrial-nuclear crosstalk, haplotype and copy number variation distinct in muscle fiber type, mitochondrial respiratory and metabolic enzyme activities. Sci Rep-UK 7: 14024, 1-12
https://dx.doi.org/10.1038/s41598-017-14491-w
Jaeger, A.; Hadlich, F.; Kemper, N.; Lübke-Becker, A.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
MicroRNA expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli in vitro. BMC Genomics 18: 660, 1-14
https://dx.doi.org/10.1186/s12864-017-4070-2
Reyer, H.; Varley, P. F.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Genetics of body fat mass and related traits in a pig population selected for leanness. Sci Rep-UK 7: 9118, 1-9
https://dx.doi.org/10.1038/s41598-017-08961-4
Reyer, H.; Oster, M.; Magowan, E.; Dannenberger, D.; Ponsuksili, S.; Wimmers, K. (2017):
Strategies towards improved feed efficiency in pigs comprise molecular shifts in hepatic lipid and carbohydrate metabolism. Int J Mol Sci 18 (8): 1674, 1-15
https://dx.doi.org/10.3390/ijms18081674
Günther, J.; Petzl, W.; Bauer, I.; Ponsuksili, S.; Zerbe, H.; Schuberth, H.-J.; Brunner, R. M.; Seyfert, H.-M. (2017):
Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection. Sci Rep-UK 7: 4811,1-14
https://dx.doi.org/10.1038/s41598-017-05107-4
Reyer, H.; Shirali, M.; Ponsuksili, S.; Muràni, E.; Varley, P. F.; Jensen, J.; Wimmers, K. (2017):
Exploring the genetics of feed efficiency and feeding behaviour traits in a pig line highly selected for performance characteristics. Mol Genet genomics 292 (5): 1001-1011
https://dx.doi.org/10.1007/s00438-017-1325-1
Oster, M.; Trakooljul, N.; Reyer, H.; Zeyner, A.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Sex-specific muscular maturation responses following prenatal exposure to methylation-related micronutrients in pigs. Nutrients 9 (1): 74-86
https://dx.doi.org/10.3390/nu9010074
Friedrich, J.; Brand, B.; Graunke, K. L.; Langbein, J.; Schwerin, M.; Ponsuksili, S. (2017):
Adrenocortical expression profiling of cattle with distinct juvenile temperament types. Behav Genet 47 (1): 102-113
https://dx.doi.org/10.1007/s10519-016-9816-0
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2016):
Genetically regulated hepatic transcripts and pathways orchestrate haematological, biochemical and body composition traits. Sci Rep-UK 6: 39614, 1-13
https://dx.doi.org/10.1038/srep39614
Reyer, H.; Ponsuksili, S.; Kanitz, E.; Pöhland, R.; Wimmers, K.; Muràni, E. (2016):
A natural mutation in helix 5 of the ligand binding domain of glucocorticoid receptor enhances receptor-ligand interaction. Plos One 11 (10): e0164628, 1-15
https://dx.doi.org/10.1371/journal.pone.0164628
Liu, X.; Trakooljul, N.; Muràni, E.; Krischek, C.; Schellander, K.; Wicke, M.; Wimmers, K.; Ponsuksili, S. (2016):
Molecular changes in mitochondrial respiratory activity and metabolic enzyme activity in muscle of four pig breeds with distinct metabolic types. J Bioenerg Biomembr 48 (1): 55-65
https://dx.doi.org/10.1007/s10863-015-9639-3
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Immediate and long-term transcriptional response of hind muscle tissue to transient variation of incubation temperature in broilers. BMC Genomics 17: 323, 1-13
https://dx.doi.org/10.1186/s12864-016-2671-9
Muràni, E.; Ponsuksili, S.; Jaeger, A.; Görres, A.; Tuchscherer, A.; Wimmers, K. (2016):
A naturally hypersensitive glucocorticoid receptor elicits a compensatory reduction of hypothalamus-pituitary-adrenal axis activity early in ontogeny. Open Biol 6 (7): 150193, 1-11
https://dx.doi.org/10.1098/rsob.150193
Ponsuksili, S.; Reyer, H.; Trakooljul, N.; Muràni, E.; Wimmers, K. (2016):
Single- and Bayesian multi-marker genome-wide association for haematological parameters in pigs. Plos One 11 (7): e0159212, 1-14
https://dx.doi.org/10.1371/journal.pone.0159212
Liu, X.; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2016):
MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities. BMC Genomics 17: 531, 1-14
https://dx.doi.org/10.1186/s12864-016-2850-8
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Transient shifts of incubation temperature reveal immediate and long-term transcriptional response in chicken breast muscle underpinning resilience and phenotypic plasticity. Plos One 11 (9): e0162485, 1-17
https://dx.doi.org/10.1371/journal.pone.0162485
Brand, B.; Scheinhardt, M. O.; Friedrich, J.; Zimmer, D.; Reinsch, N.; Ponsuksili, S.; Schwerin, M.; Ziegler, A. (2016):
Adrenal cortex expression quantitative trait loci in a German Holstein x Charolais cross (Erratum in 17: 148). BMC Genet 17: 135, 1-11
https://dx.doi.org/10.1186/s12863-016-0442-x
Ohde, D.; Moeller, M.; Brenmoehl, J.; Walz, C.; Ponsuksili, S.; Schwerin, M.; Fuellen, G.; Hoeflich, A. (2016):
Advanced running performance by genetic predisposition in male Dummerstorf marathon mice (DUhTP) reveals higher sterol regulatory element-binding protein (SREBP) related mRNA expression in the liver and higher serum levels of progesterone. Plos One 11 (1): e0146748, 1-16
https://dx.doi.org/10.1371/journal.pone.0146748