PD Dr. sc. agr. habil. Siriluck Wimmers

Research Institute for Farm Animal Biology (FBN)
Head of Working group Integrative Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Molecular genetics and expression of traits related to meat quality and other productive traits in livestock
  • miRNA regulatory network involved in energy metabolism and meat quality in muscle cells
  • Trait-associated variation at the molecular levels of the genotype-phenotype map

Curriculum Vitae

  • Since 2014: Head of unit Functional Genome Analysis, Institute of Genome Biology, FBN
  • 2004-2013: Senior Scientist, Functional Genome Analysis, FBN
  • 2003: Habilitation, venia legendi Animal Breeding and Genetics, University of Bonn
  • 1997-2003: Scientist at the Faculty of Agriculture, Rheinische Friedrich-Wilhelm-University Bonn
  • 1997: Assisted Professor of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand
  • 1990-1995: DAAD-Scholarship, Doctoral student at the Institute of Animal production, TU Berlin
  • 1987-1997: Lecturer of Department of Animal Science, Faculty of Agriculture, University of Chiang Mai, Thailand

Teaching

Lectures and seminars at the Faculty of Agriculture, University of Bonn

Publications

Gerlinger, Ch.; Oster, M.; Borgelt, L.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Polley, C.; Vollmar, B.; Reichel, M.; Wolf, P; Wimmers, K. (2019):
Physiological and transcriptional responses in weaned piglets fed diets with varying phosphorus and calcium levels. Nutrients 11 (2): 436, 1-15
https://doi.org/10.3390/nu11020436
Sokolov, E. P.; Markert, S.; Hinzke, T.; Hirschfeld, C.; Becher, D.; Ponsuksili, S.; Sokolova, I. M. (2019):
Effects of hypoxia-reoxygenation stress on mitochondrial proteome and bioenergetics of the hypoxia-tolerant marine bivalve Crassostrea gigas. J Proteomics 194: 99-111
https://doi.org/10.1016/j.jprot.2018.12.009
Naraballobh, W; Trakooljul, N.; Muráni, E.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2018):
miRNAs regulate acute transcriptional changes in broiler embryos in response to modification of incubation temperature. Sci Rep-UK 8: 11371, 1-12
https://doi.org/10.1038/s41598-018-29316-7
Reyer, H.; Metzler-Zebeli, B.U.; Trakooljul, N.; Oster, M.; Muráni, E.; Ponsuksili, S.; Hadlich, F.; Wimmers, K. (2018):
Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens. Sci Rep-UK 8: 12903, 1-9
https://doi.org/10.1038/s41598-018-31072-7
Reyer, H.; Oster, M.; Magowan, E.; Muráni, E.; Sauerwein, H.; Dannenberger, D.; Kuhla, B.; Ponsuksili, S.; Wimmers, K. (2018):
Feed-efficient pigs exhibit molecular patterns allowing a timely circulation of hormones and nutrients. Physiol Genomics 50 (9): 726-734
https://doi.org/10.1152/physiolgenomics.00021.2018
Just, F.; Oster, M.; Büsing, K.; Borgelt, L.; Muráni, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2018):
Lowered dietary phosphorus affects intestinal and renal gene expression to maintain mineral homeostasis with immunomodulatory implications in weaned piglets. BMC Genomics 19: 207, 1-11
https://doi.org/10.1186/s12864-018-4584-2
Just, F.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Oster, M.; Wimmers, K. (2018):
Genetic variants of major genes contributing to phosphate and calcium homeostasis and their association with serum parameters in pigs. J Appl Genet 59 (3): 325-333
https://doi.org/10.1007/s13353-018-0449-2
Oster, M.; Gerlinger, Ch.; Heide, K.; Just, F.; Borgelt, L.; Wolf, C.; Polley, C.; Vollmar, B.; Muráni, E.; Ponsuksili, S.; Wimmers, K. (2018):
Lower dietary phosphorus supply in pigs match both animal welfare aspects and resource efficiency. Ambio 47 (Suppl. 1): 20-29
https://doi.org/10.1007/s13280-017-0969-8
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2017):
Genetic architecture and regulatory impact on hepatic microRNA expression linked to immune and metabolic traits. Open Biol 7 (11): 170101, 1-11
https://dx.doi.org/10.1098/rsob.170101
Liu, X; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
Mitochondrial-nuclear crosstalk, haplotype and copy number variation distinct in muscle fiber type, mitochondrial respiratory and metabolic enzyme activities. Sci Rep-UK 7: 14024, 1-12
https://dx.doi.org/10.1038/s41598-017-14491-w
Jaeger, A.; Hadlich, F.; Kemper, N.; Lübke-Becker, A.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2017):
MicroRNA expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli in vitro. BMC Genomics 18: 660, 1-14
https://dx.doi.org/10.1186/s12864-017-4070-2
Reyer, H.; Varley, P. F.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Genetics of body fat mass and related traits in a pig population selected for leanness. Sci Rep-UK 7: 9118, 1-9
https://dx.doi.org/10.1038/s41598-017-08961-4
Reyer, H.; Oster, M.; Magowan, E.; Dannenberger, D.; Ponsuksili, S.; Wimmers, K. (2017):
Strategies towards improved feed efficiency in pigs comprise molecular shifts in hepatic lipid and carbohydrate metabolism. Int J Mol Sci 18 (8): 1674, 1-15
https://dx.doi.org/10.3390/ijms18081674
Günther, J.; Petzl, W.; Bauer, I.; Ponsuksili, S.; Zerbe, H.; Schuberth, H.-J.; Brunner, R. M.; Seyfert, H.-M. (2017):
Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection. Sci Rep-UK 7: 4811,1-14
https://dx.doi.org/10.1038/s41598-017-05107-4
Reyer, H.; Shirali, M.; Ponsuksili, S.; Muràni, E.; Varley, P. F.; Jensen, J.; Wimmers, K. (2017):
Exploring the genetics of feed efficiency and feeding behaviour traits in a pig line highly selected for performance characteristics. Mol Genet genomics 292 (5): 1001-1011
https://dx.doi.org/10.1007/s00438-017-1325-1
Oster, M.; Trakooljul, N.; Reyer, H.; Zeyner, A.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2017):
Sex-specific muscular maturation responses following prenatal exposure to methylation-related micronutrients in pigs. Nutrients 9 (1): 74-86
https://dx.doi.org/10.3390/nu9010074
Friedrich, J.; Brand, B.; Graunke, K. L.; Langbein, J.; Schwerin, M.; Ponsuksili, S. (2017):
Adrenocortical expression profiling of cattle with distinct juvenile temperament types. Behav Genet 47 (1): 102-113
https://dx.doi.org/10.1007/s10519-016-9816-0
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2016):
Genetically regulated hepatic transcripts and pathways orchestrate haematological, biochemical and body composition traits. Sci Rep-UK 6: 39614, 1-13
https://dx.doi.org/10.1038/srep39614
Reyer, H.; Ponsuksili, S.; Kanitz, E.; Pöhland, R.; Wimmers, K.; Muràni, E. (2016):
A natural mutation in helix 5 of the ligand binding domain of glucocorticoid receptor enhances receptor-ligand interaction. Plos One 11 (10): e0164628, 1-15
https://dx.doi.org/10.1371/journal.pone.0164628
Liu, X.; Trakooljul, N.; Muràni, E.; Krischek, C.; Schellander, K.; Wicke, M.; Wimmers, K.; Ponsuksili, S. (2016):
Molecular changes in mitochondrial respiratory activity and metabolic enzyme activity in muscle of four pig breeds with distinct metabolic types. J Bioenerg Biomembr 48 (1): 55-65
https://dx.doi.org/10.1007/s10863-015-9639-3