PD Dr. biol. hom. habil. Sebastian Peter Galuska
Research interests
- Glycobiology
- Reproductive Biology
- Immunology
- Glycoanalytic
Curriculum Vitae
- since 2020: Head of the Glycobiology Unit at the Institute of Reproductive Biology, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2016–2020: Junior Group Leader at the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2012–2016: Junior Group leader at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2008–2012: Postdoctoral Research Fellow at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2008: Dr. in human biology, Dr. biol. hom.
- 2003–2008: PhD student at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2003: Dipl. Ing. in Biotechnology
- 1999–2003: Studies in Biotechnology at the University of applied Sciences Giessen/Friedberg (THM), Germany, Germany
Teaching
since 2005: Different practical courses, seminars and lectures in the disciplines of biology and biochemistry in the Medical Faculty as well as in the Faculty of Psychology and Sports Science at the Justus-Liebig University Giessen, Germany
Publications
Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):
Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):
https://doi.org/10.1186/s13578-018-0262-y
Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):
Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10
https://doi.org/10.3390/ijms18061679
Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):
Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231
https://doi.org/10.1016/j.dci.2018.05.008
Zlatina, K.; Lütteke, T.; Galuska, S. P. (2017):
Individual impact of distinct polysialic acid chain lengths on the cytotoxicity of histone H1, H2A, H2B, H3 und H4. POLYMERS-BASEL 9 (12): 720, 1-13
https://dx.doi.org/10.3390/polym9120720
Galuska, C.E.; Dambon, J.; Kühnle, A.; Bornhöfft, K.; Prem, G.; Zlatina, K.; Lütteke, T.; Galuska, S. P. (2017):
Artificial polysialic acid chains as sialidase-resistant molecular-anchors to accumulate particles on neutrophil extracellular traps. Front Immunol 8: 1229, 1-10
https://dx.doi.org/10.3389/fimmu.2017.01229
Chan, K.H.; Galuska, S. P.; Kudipudi, P.K.; Riaz, M.A.; Loveland, K.L.; Konrad, L. (2017):
Signaling by TGF-betas in tubule cultures of adult rat testis. Am J Transl Res 9 (3): 1173-1182
Galuska, S. P.; Galuska, C.E.; Tharmalingam, T; Zlatina, K.; Prem, G.; Husejnov, F.C.O.; Rudd, P.M.; Vann, W.F.; Reid, C.; Vionnet, J.; Gallagher, M.E.; Carrington, F.A.; Hassett, S.L.; Carrington, S.D. (2017):
In vitro generation of polysialylated cervical mucins by bacterial polysialyltransferases to counteract cytotoxicity of extracellular histones. FEBS J 284 (11): 1688-1699
https://dx.doi.org/10.1111/febs.14073
Galuska, C.E.; Lütteke, T.; Galuska, S. P. (2017):
Is polysialylated NCAM not only a regulator during brain development but also during the formation of other organs?. BIOLOGY-BASEL 6 (2): 27,1-15
https://dx.doi.org/10.3390/biology6020027
Chen, S.; Palma Vera, S. E.; Langhammer, M.; Galuska, S. P.; Braun, B.C.; Krause, E.; Lucas-Hahn, A.; Schön, J. (2017):
An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Sci Rep-UK 7: 42298, 1-7
https://dx.doi.org/10.1038/srep42298
Zhang, R.; Loers, G.; Schachner, M.; Boelens, R.; Wienk, H.; Siebert, S.; Eckert, T.; Kraan, S.; Rojas-Macias, M.; Lütteke, T.; Galuska, S. P.; Scheidig, A.; Petridis, A.; Liang, S.; Billeter, M.; Schauer, R.; Steinmeyer, J.; Schröder, J.J.; Siebert, H. (2016):
Molecular basis of the receptor interactions of polysialic acid (polySia), polySia mimetics, and sulfated polysaccharides. ChemMedChem 11 (9): 990-1002
https://dx.doi.org/10.1002/cmdc.201500609
Khosravi, F.; Michel, V.; Galuska, C. E.; Bhushan, S.; Christian, P.; Schuppe, H.C.; Pilatz, A.; Galuska, S. P.; Meinhardt, A. (2016):
Desialylation of spermatozoa and epithelial cell glycocalyx is a consequence of bacterial infection of the epididymis. J Biol Chem 291 (34): 17717-17726
https://dx.doi.org/10.1074/jbc.M116.718072
Kallolimath, S.; Castilho, A.; Strasser, R.; Grünwald-Gruber, C.; Altmann, F.; Strubl, S.; Galuska, C. E.; Zlatina, K.; Galuska, S. P.; Werner, S.; Thiesler, H.; Werneburg, S.; Hildebrandt, T.; Gerardy-Schahn, R.; Steinkellner, H. (2016):
Engineering of complex protein sialylation in plants. P Natl Acad Sci USA 113 (34): 9498-9503
https://dx.doi.org/10.1073/pnas.1604371113