PD Dr. biol. hom. Sebastian Peter Galuska

+49 38208 68 752
Research Institute for Farm Animal Biology (FBN)
Institute of Reproductive Biology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Glycobiology
  • Reproductive Biology
  • Immunology
  • Glycoanalytic

Curriculum Vitae

  • since 2020: Head of the Glycobiology Unit at the Institute of Reproductive Biology, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
  • 2016–2020: Junior Group Leader at the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
  • 2012–2016: Junior Group leader at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2008–2012: Postdoctoral Research Fellow at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2008: Dr. in human biology, Dr. biol. hom.
  • 2003–2008: PhD student at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2003: Dipl. Ing. in Biotechnology
  • 1999–2003: Studies in Biotechnology at the University of applied Sciences Giessen/Friedberg (THM), Germany, Germany

Teaching

since 2005: Different practical courses, seminars and lectures in the disciplines of biology and biochemistry in the Medical Faculty as well as in the Faculty of Psychology and Sports Science at the Justus-Liebig University Giessen, Germany

Publications

Magray, A. R.; Martorell Ribera, J.; Isernhagen, L.; Galuska, S. P.; Günther, J.; Verleih, M.; Viergutz, T.; Brunner, R. M.; Ganai, B.; Ahmad, F.; Zlatina, K.; Rebl, A. (2021):
Evaluation of blood cell viability rate, gene expression, and O-GlcNAcylation profiles as indicative signatures for fungal stimulation of salmonid cell models. MOL IMMUNOL 142: 120-129
https://doi.org/10.1016/j.molimm.2021.12.019
Kühnle, A.; Galuska, C.E.; Zlatina, K.; Galuska, S. P. (2020):
The bovine antimicrobial peptide lactoferricin interacts with polysialic acid without loss of its antimicrobial activity against Escherichia coli. Animals-Basel 10 (1): 1, 1--12
https://doi.org/10.3390/ani10010001
Venuto, M. T.; Decloquement, M.; Martorell Ribera, J.; Noel, M.; Rebl, A.; Cogez, V.; Petit, D.; Galuska, S. P.; Harduin-Lepers, A. (2020):
Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective. Int J Mol Sci 21 (2): 513, 1-21
https://doi.org/10.3390/ijms21020513
Bornhöfft, K.; Martorell Ribera, J.; Viergutz, T.; Venuto, M. T.; Gimsa, U.; Galuska, S. P.; Rebl, A. (2020):
Characterization of sialic acid-binding immunoglobulin-type lectins in fish reveals teleost-specific structures and expression patterns. Cells-Basel 9 (4): 836, 1-19
https://doi.org/10.3390/cells9040836
Zlatina, K.; Galuska, S. P. (2020):
The N-glycans of lactoferrin: More than just a sweet decoration. Biochem Cell Biol 99 (1): 117-127
https://doi.org/10.1139/bcb-2020-0106
Venuto, M. T.; Martorell Ribera, J.; Bochert, R.; Harduin-Lepers, A; Rebl, A.; Galuska, S. P. (2020):
Characterization of the polysialylation status in ovaries of the salmonid fish Coregonus maraena and the percid fish Sander lucioperca. Cells-Basel 9 (11): 2391, 1-15
https://doi.org/10.3390/cells9112391
Galuska, C.E.; Rudloff, S.; Kunz, S.; Borsch, C; Reutzel, M.; Eckert, G; Galuska, S. P.; Kunz, C. (2020):
Metabolic fate and organ distribution of 13C-3′-sialyllactose and 13C-N-acetylneuraminic acid in wild-type mice – No evidence for direct incorporation into the brain. J Funct Foods 75: 104268, 1-10
https://doi.org/10.1016/j.jff.2020.104268
Kronimus, Y.; Dodel, R.; Galuska, S. P.; Neumann, S. (2019):
IgG Fc N-glycosylation: Alterations in neurologic diseases and potential therapeutic target?. J Autoimmun 96: 14-23
https://doi.org/10.1016/j.jaut.2018.10.006
Kühnle, A.; Veelken, R.; Galuska, C.E.; Saftenberger, M.; Verleih, M.; Schuppe, H.C.; Rudloff, S.; Kunz, C.; Galuska, S. P. (2019):
Polysialic acid interacts with lactoferrin and supports its activity to inhibit the release of neutrophil extracellular traps. Carbohyd Polym 208: 32-41
https://doi.org/10.1016/j.carbpol.2018.12.033
Zlatina, K.; Galuska, S. P. (2019):
Polysialic acid modulates only the antimicrobial properties of distinct histones. ACS Omega 4 (1): 1601-1610
https://doi.org/10.1021/acsomega.8b02222
Kühnle, A.; Lütteke, T.; Bornhöfft, K.; Galuska, S. P. (2019):
Polysialic acid modulates the binding of external lactoferrin in neutrophil extracellular traps. BIOLOGY-BASEL 8 (2): 20
https://doi.org/10.3390/biology8020020
Bornhöfft, K.; Galuska, S. P. (2019):
Glycans as modulators for the formation and functional properties of neutrophil extracellular traps: used by the forces of good and evil. Front Immunol 10: 959, 1-9
https://doi.org/10.3389/fimmu.2019.00959
Bornhöfft, K.; Rebl, A.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P. (2019):
Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol 10: 2478, 1-15
https://doi.org/10.3389/fimmu.2019.02478
Kudipudi, P.K.; Galuska, S. P.; Dietze, R.; Scheiner-Bobis, G.; Loveland, K.; Konrad, L (2019):
Betaglycan (TβRIII) is a key factor in TGF-β2 sSignaling in prepubertal rat sertoli cells. Int J Mol Sci 20 (24): 6214, 1-18
https://doi.org/10.3390/ijms20246214
Bornhöfft, K.; Viergutz, T.; Kühnle, A.; Galuska, S. P. (2019):
Nanoparticles equipped with 2,8-linked sialic acid chains inhibit the release of neutrophil extracellular traps. Nanomaterials-Basel 9 (4): 610, 1-16
https://doi.org/10.3390/nano9040610
Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):
Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231
https://doi.org/10.1016/j.dci.2018.05.008
Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):
Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10
https://doi.org/10.3390/ijms18061679
Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):
Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):
https://doi.org/10.1186/s13578-018-0262-y
Chen, S.; Palma Vera, S.; Langhammer, M.; Galuska, S. P.; Braun, B.C.; Krause, E.; Lucas-Hahn, A.; Schön, J. (2017):
An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Sci Rep-UK 7: 42298, 1-7
https://dx.doi.org/10.1038/srep42298
Galuska, C.E.; Lütteke, T.; Galuska, S. P. (2017):
Is polysialylated NCAM not only a regulator during brain development but also during the formation of other organs?. BIOLOGY-BASEL 6 (2): 27,1-15
https://dx.doi.org/10.3390/biology6020027