PD Dr. biol. hom. habil. Sebastian Peter Galuska
Research Institute for Farm Animal Biology (FBN)
Head of working group Glycoimmunology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of working group Glycoimmunology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Glycobiology
- Reproductive Biology
- Immunology
- Glycoanalytic
Curriculum Vitae
- since 2020: Head of the Glycobiology Unit at the Institute of Reproductive Biology, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2016–2020: Junior Group Leader at the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2012–2016: Junior Group leader at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2008–2012: Postdoctoral Research Fellow at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2008: Dr. in human biology, Dr. biol. hom.
- 2003–2008: PhD student at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
- 2003: Dipl. Ing. in Biotechnology
- 1999–2003: Studies in Biotechnology at the University of applied Sciences Giessen/Friedberg (THM), Germany, Germany
Teaching
since 2005: Different practical courses, seminars and lectures in the disciplines of biology and biochemistry in the Medical Faculty as well as in the Faculty of Psychology and Sports Science at the Justus-Liebig University Giessen, Germany
Publications
Teppa, R. E.; Galuska, S. P.; Harduin-Lepers, A. (2024):
Molecular dynamics simulations shed light into the donor substrate specificity of vertebrate poly-alpha-2,8-sialyltransferases ST8Sia IV
BBA – General Subjects 1868: 130647, 1-10
https://doi.org/10.1016/j.bbagen.2024.130647
Zlatina, K.; Isernhagen, L.; Galuska, C. E.; Muráni, E.; Galuska, S. P. (2024):
Changes in the N-glycosylation of porcine immune globulin G during postnatal development.
Frontiers in Immunology 15: 1361240, 1-12
https://doi.org/10.3389/fimmu.2024.1361240
Hinterseher, J.; Günther, J.; Zlatina, K.; Isernhagen, L.; Viergutz, T.; Wirthgen, E.; Höflich, A.; Vernunft, A.; Galuska, S. P. (2023):
Milk Polysialic Acid Levels Rapidly Decrease in Line with the N-Acetylneuraminic Acid Concentrations during Early Lactation in Dairy Cows. BIOLOGY-BASEL 12 (1): 5, 1-12
Juliane Günther,
Kristina Zlatina,
Sebastian Peter Galuska,
Andreas Höflich,
Andreas Vernunft,
Christina Galuska
Barnieh, F. M.; Galuska, S. P.; Loadman, P. M.; Ward, S.; Falconer, R. A.; El-Khamisy, S. F. (2023):
Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues
iScience 26 (11): 108219, 1-14
https://doi.org/10.1016/j.isci.2023.108219
Decloquement, M.; Venuto, M. T.; Cogez, V.; Steinmetz, A.; Schulz, C.; Lion, C.; Noel, M.; Rigolot, V.; teppa, R.; Biot, C.; Rebl, A.; Galuska, S. P.; Harduin-Lepers, A (2023):
Salmonid polysialyltransferases to generate a variety of sialic acid polymers. Sci Rep-UK 13: 15610, 1-14
Magray, A. R.; Martorell Ribera, J.; Isernhagen, L.; Galuska, S. P.; Günther, J.; Verleih, M.; Viergutz, T.; Brunner, R. M.; Ganai, B.; Ahmad, F.; Zlatina, K.; Rebl, A. (2022):
Evaluation of blood cell viability rate, gene expression, and O-GlcNAcylation profiles as indicative signatures for fungal stimulation of salmonid cell models. MOL IMMUNOL 142: 120-129
Alexander Rebl,
Kristina Zlatina,
Marieke Verleih,
Juliane Günther,
Christina Galuska,
Sebastian Peter Galuska
https://doi.org/10.1016/j.molimm.2021.12.019
Galuska, C.E.; Rudloff, S.; Kunz, S.; Borsch, C; Reutzel, M.; Eckert, G; Galuska, S. P.; Kunz, C. (2020):
Metabolic fate and organ distribution of 13C-3′-sialyllactose and 13C-N-acetylneuraminic acid in wild-type mice – No evidence for direct incorporation into the brain. J Funct Foods 75: 104268, 1-10
https://doi.org/10.1016/j.jff.2020.104268
Venuto, M. T.; Martorell Ribera, J.; Bochert, R.; Harduin-Lepers, A; Rebl, A.; Galuska, S. P. (2020):
Characterization of the polysialylation status in ovaries of the salmonid fish Coregonus maraena and the percid fish Sander lucioperca. Cells-Basel 9 (11): 2391, 1-15
https://doi.org/10.3390/cells9112391
Zlatina, K.; Galuska, S. P. (2020):
The N-glycans of lactoferrin: More than just a sweet decoration. Biochem Cell Biol 99 (1): 117-127
https://doi.org/10.1139/bcb-2020-0106
Bornhöfft, K.; Martorell Ribera, J.; Viergutz, T.; Venuto, M. T.; Gimsa, U.; Galuska, S. P.; Rebl, A. (2020):
Characterization of sialic acid-binding immunoglobulin-type lectins in fish reveals teleost-specific structures and expression patterns. Cells-Basel 9 (4): 836, 1-19
https://doi.org/10.3390/cells9040836
Venuto, M. T.; Decloquement, M.; Martorell Ribera, J.; Noel, M.; Rebl, A.; Cogez, V.; Petit, D.; Galuska, S. P.; Harduin-Lepers, A. (2020):
Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective. Int J Mol Sci 21 (2): 513, 1-21
https://doi.org/10.3390/ijms21020513
Kühnle, A.; Galuska, C.E.; Zlatina, K.; Galuska, S. P. (2020):
The bovine antimicrobial peptide lactoferricin interacts with polysialic acid without loss of its antimicrobial activity against Escherichia coli. Animals-Basel 10 (1): 1, 1--12
https://doi.org/10.3390/ani10010001
Bornhöfft, K.; Viergutz, T.; Kühnle, A.; Galuska, S. P. (2019):
Nanoparticles equipped with 2,8-linked sialic acid chains inhibit the release of neutrophil extracellular traps. Nanomaterials-Basel 9 (4): 610, 1-16
https://doi.org/10.3390/nano9040610
Kudipudi, P.K.; Galuska, S. P.; Dietze, R.; Scheiner-Bobis, G.; Loveland, K.; Konrad, L (2019):
Betaglycan (TβRIII) is a key factor in TGF-β2 sSignaling in prepubertal rat sertoli cells. Int J Mol Sci 20 (24): 6214, 1-18
https://doi.org/10.3390/ijms20246214
Bornhöfft, K.; Rebl, A.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P. (2019):
Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol 10: 2478, 1-15
https://doi.org/10.3389/fimmu.2019.02478
Bornhöfft, K.; Galuska, S. P. (2019):
Glycans as modulators for the formation and functional properties of neutrophil extracellular traps: used by the forces of good and evil. Front Immunol 10: 959, 1-9
https://doi.org/10.3389/fimmu.2019.00959
Kühnle, A.; Lütteke, T.; Bornhöfft, K.; Galuska, S. P. (2019):
Polysialic acid modulates the binding of external lactoferrin in neutrophil extracellular traps. BIOLOGY-BASEL 8 (2): 20
https://doi.org/10.3390/biology8020020
Zlatina, K.; Galuska, S. P. (2019):
Polysialic acid modulates only the antimicrobial properties of distinct histones. ACS Omega 4 (1): 1601-1610
https://doi.org/10.1021/acsomega.8b02222
Kühnle, A.; Veelken, R.; Galuska, C.E.; Saftenberger, M.; Verleih, M.; Schuppe, H.C.; Rudloff, S.; Kunz, C.; Galuska, S. P. (2019):
Polysialic acid interacts with lactoferrin and supports its activity to inhibit the release of neutrophil extracellular traps. Carbohyd Polym 208: 32-41
https://doi.org/10.1016/j.carbpol.2018.12.033
Kronimus, Y.; Dodel, R.; Galuska, S. P.; Neumann, S. (2019):
IgG Fc N-glycosylation: Alterations in neurologic diseases and potential therapeutic target?. J Autoimmun 96: 14-23
https://doi.org/10.1016/j.jaut.2018.10.006