Dr. rer. nat. Rainer Fürbaß

+49 38208 68-752
Research Institute for Farm Animal Biology (FBN)
Institute of Reproductive Biology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Publications

Fürbaß, R.; Michaelis, M.; Schuler, G (2022):
Unhatched bovine blastocysts express all transcripts of the estrogen biosynthetic pathway, but steroid hormone synthesis could not yet be demonstrated [epublished ahead of print]. DOMEST ANIM ENDOCRIN
https://doi.org/10.1016/j.domaniend.2022.106770
Polei, M.; Günther, J.; Koczan, D.; Fürbaß, R. (2020):
Trophoblast cell differentiation in the bovine placenta: Differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis. BMC Mol Cell Biol 21: 1, 1-12
https://doi.org/10.1186/s12860-020-0246-8
Polei, M.; Günther, J.; Koczan, D.; Fürbaß, R. (2020):
Gene expression profiles of bovine uninucleate trophoblast cells and trophoblast giant cells: a data note. BMC Res Notes 13: 115, 1-3
https://doi.org//10.1186/s13104-020-04964-z
Schuler, G; Fürbaß, R.; Klisch, K. (2018):
Placental contribution to the endocrinology of gestation and parturition. Anim Reprod 15 (Suppl. 1): 822-842
https://doi.org/10.21451/1984-3143-AR2018-0015
Chwalisz, M.; Fürbaß, R. (2014):
Evaluation of coding-independent functions of the transcribed bovine aromatase pseudogene CYP19P1. BMC Res Notes 7: 378-383
https://dx.doi.org/10.1186/1756-0500-7-378
Polei, M.; Viergutz, T.; Tomek, W.; Schuler, G.; Fürbaß, R. (2014):
Estrogen-specific sulfotransferase (SULT1E1) in bovine placentomes: inverse levels of mRNA and protein in uninucleated trophoblast cells and trophoblast giant cells . Biol Reprod 91 (2): 48-56
https://dx.doi.org/10.1095/biolreprod.114.118760
Chwalisz, M.; Viergutz, T.; Tomek, W.; Schuler, G.; Fürbaß, R. (2014):
Estrogen-specific sulfotransferase SULT1E1 in bovine placentomes: predominant expression in uninucleated trophoblast cells balances the local availability of estrogens. In: 15th Day of the Doctoral Student : abstracts, 13 May 2014 Dummerstorf (Schriftenreihe / Leibniz-Institut für Nutztierbiologie , 23) (Christa Kühn, Gunther Viereck, Hrsg.): 13-16
Vanselow, J.; Fürbaß, R. (2011):
The bovine genome contains three differentially methylated paralogous copies of the P450c17 encoding gene (CYP17A1). Gen Comp Endocr 170 (3): 475-479
https://dx.doi.org/10.1016/j.ygcen.2010.11.003
Vanselow, J.; Spitschak, M.; Nimz, M.; Fürbaß, R. (2010):
DNA methylation is not involved in preovulatory down-regulation of CYP11A1, HSD3B1, and CYP19A1 in bovine follicles but may have a role in permanent silencing of CYP19A1 in large granulosa lutein cells. Biol Reprod 82 (2): 289-298
https://dx.doi.org/10.1095/biolreprod.109.079251
Fürbaß, R.; Tomek, W.; Vanselow, J. (2010):
Upstream Stimulating Factors 1 and 2 Enhance Transcription from the Placenta-Specific Promoter 1.1 of the Bovine Cyp19 Gene. BMC Mol Biol 11: 5
Vanselow, J.; Fürbaß, R. (2010):
Epigenetic control of folliculogenesis and luteinization. Anim Reprod 7 (3): 134-139
Nimz, M.; Spitschak, M.; Fürbaß, R.; Vanselow, J. (2010):
The preovulatory luteinizing hormone surge is followed by downregulation of CYP19A1, HSD3B1 and CYP17A1 and chromatin condensation of the corresponding promoters in bovine follicles. Mol Reprod Dev 77: 1040-1048
https://dx.doi.org/10.1002/mrd.21257
Nimz, M.; Spitschak, M.; Schneider, F.; Fürbaß, R.; Vanselow, J. (2009):
Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids. DOMEST ANIM ENDOCRIN 37 (1): 45-54
https://dx.doi.org/10.1016/j.domaniend.2009.02.002
Fürbaß, R.; Selimyan, R.; Vanselow, J. (2008):
DNA methylation and chromatin accessibility of the proximal Cyp19 promoter region 1.5/2 correlate with expression levels in sheep placentomes. Mol Reprod Dev 75 (1): 1-7
https://dx.doi.org/10.1002/mrd.20756
Vanselow, J.; Fürbaß, R.; Tiemann, U. (2008):
Cultured bovine trophoblast cells differentially express genes encoding key steroid synthesis enzymes. Placenta 29 (6): 531-538
https://dx.doi.org/10.1016/j.placenta.2008.03.
Vanselow, J.; Selimyan, R.; Fürbaß, R. (2008):
DNA methylation of placenta-specific Cyp19 promoters of cattle and sheep. Exp Clin Endocr Diab 116 (7): 437-442
https://dx.doi.org/10.1055/s-2008-1058083
Fürbaß, R.; Winter, A.; Fries, R.; Kühn, Ch. (2006):
Alleles of the bovine DGAT1 variable number of tandem repeat associated with a milk fat QTL at chromosome 14 can stimulate gene expression. Physiol Genomics 25 (1): 116-120
https://dx.doi.org/10.1152/physiolgenomics.00145.2005
Vanselow, J.; Viergutz, T.; Fürbaß, R. (2006):
Repression of the aromatase gene (CYP19) during luteinization coincides with DANN methylation of a specific CpG dinucleotide within promoter 2. In: Proc. 8th World Congress on Genetics Applied to Livestock Production (Comm.11-11):
Vanselow, J.; Pöhland, R.; Fürbaß, R. (2005):
Promoter-2-derived Cyp19 expression in bovine granulosa cells coincides with gene-specific DNA hypo-methylation. Mol Cell Endocrinol 233 (1-2): 57-64
https://dx.doi.org/10.1016/j.mce.2005.01.007
Freese, L.G.; Rehfeldt, C.; Fürbaß, R.; Kuhn, G.; Okamura, C.S.; Ender, K.; Grant, A.L.; Gerrard, D.E. (2005):
Exogenous somatotropin alters IGF axis in porcine endometrium and placenta. DOMEST ANIM ENDOCRIN 29 (3): 457-475
https://dx.doi.org/10.1016/j.domaniend.2005.02.012