PD Dr. rer. nat. habil. Jens Vanselow

+49 38208 68-752
Leibniz Institute for Farm Animal Biology (FBN)
Institute of Reproductive Biology
Director
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Reproductive Biology
  • Folliculogenesis, Luteinization
  • Gene Regulation
  • Epigenetics

Curriculum Vitae

  • 2013-present: Head of the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2002: Habilitation and Lecturer at the Faculty of Mathematics and Natural Sciences and the Faculty of Agricultural and Environmental Sciences at the University of Rostock
  • 1992-2012: Head of the Gene Regulation Group at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Research Unit Molecular Biology
  • 1990-1992: Postdoctoral Grant, Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow at Massachusetts General Hospital, Institute for Developmental Biology, Boston, USA
  • 1988-1990: Member of the DFG Graduate College "Neurobiology", Eberhard Karls University Tübingen, Germany
  • 1990: Graduation (Dr. rer. nat.) at Eberhard Karls University Tübingen and Max-Planck-Institute for Developmental Biology, Tübingen, Germany
  • 1987: Diploma Biology at Eberhard Karls University Tübingen, Germany
  • 1983: Prediploma Biology at Johannes Gutenberg University Mainz, Germany

Teaching

  • 2013-present: "Population Genetics, Molecular Animal Breeding and Reproductive Technology" (MSc), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2014-present: "Breeding Programs and Reproduction Management" (B.Sc.), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2011-present: "Molecular Animal Breeding" (MSc), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
  • 1997-2010: "Molecular Mechanisms of Development and Differentiation" (Dipl-Biol), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany

Publications

Vanselow, J.; Christenson, L. K.; Pate, J. L. (2020):
Editorial: Regulation of dynamic changes and remodeling events during the formation, rescue and regression of the corpus luteum. Front Endocrinol 11: 244, 1-2
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
Sharma, A.; Baddela, V. S.; Becker, F.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
Baddela, V. S.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
Global gene expression analysis indicates that small luteal cells are involved in extracellular matrix modulation and immune cell recruitment in the bovine corpus luteum. Mol Cell Endocrinol 474: 201-213
Baufeld, A.; Vanselow, J. (2018):
Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage. Reprod Biol Endocrin 16: 15, 1-11
Baddela, V. S.; Sharma, A.; Viergutz, T.; Koczan, D.; Vanselow, J. (2018):
Low oxygen levels induce early luteinization associated changes in bovine granulosa cells. Front Physiol 9: 1066, 1-15
Baddela, V. S.; Sharma, A.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
mRNA microarraydata of FACS purified bovine small and large luteal cells. Data in brief 19: 737-742
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. 139: e58208
Baufeld, A.; Koczan, D.; Vanselow, J. (2017):
Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density. Reprod Biol Endocrin 15: 3, 1-14
Yenuganti, V.; Vanselow, J. (2017):
Cultured bovine granulosa cells rapidly lose important features of their identity and functionality but partially recover under long-term culture conditions. Cell Tissue Res 368 (2): 397-403
Yenuganti, V.; Vanselow, J. (2017):
Oleic acid induces down-regulation of the granulosa cell identity marker FOXL2, and up-regulation of the Sertoli cell marker SOX9 in bovine granulosa cells. Reprod Biol Endocrin 15: 57, 1-5
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Metges, C. C. (2016):
Maternal high-protein diet during pregnancy, but not during suckling, induced altered expression of an increasing number of hepatic genes in adult mouse offspring. Eur J Nutr 55 (3): 917-930
Yenuganti, V.; Viergutz, T.; Vanselow, J. (2016):
Oleic acid induces specific alterations in the morphology, gene expression and steroid hormone production of cultured bovine granulosa cells. Gen Comp Endocr 232: 134-144
Vanselow, J.; Vernunft, A.; Koczan, D.; Spitschak, M.; Kuhla, B. (2016):
Exposure of lactating dairy cows to acute pre-ovulatory heat stress affects granulosa cell-specific gene expression profiles in dominant follicles. Plos One 11 (8): e0160600, 1-19
Shrestha, K.; Lukasik, K.; Baufeld, A.; Vanselow, J.; Moallem, U.; Meidan, R. (2015):
Regulation of ovulatory genes in bovine granulosa cells: lessons from siRNA silencing of PTGS2. Reproduction 149 (1): 21-29
Chang, G.; Petzl, W.; Vanselow, J.; Günther, J.; Shen, Z.; Seyfert, H.-M. (2015):
Epigenetic mechanisms contribute to enhanced expression of immune response genes in the liver of cows after experimentally induced Escherichia coli mastitis. Vet J 203 (3): 339-341
Yenuganti, V.; Baddela, V.S.; Baufeld, A.; Singh, D.; Vanselow, J. (2015):
The gene expression pattern induced by high plating density in cultured bovine and buffalo granulosa cells might be regulated by specific miRNA species. J Reprod Develop 61 (2): 154-160
Kunze, M.; Wirthgen, E.; Walz, C.; Spitschak, M.; Brenmoehl, J.; Vanselow, J.; Schwerin, M.; Wimmers, K.; Hoeflich, A. (2015):
Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC-MS/MS. J Chromatogr B 1007: 132-139