PD Dr. rer. nat. habil. Manfred Mielenz
+49 38208 68-652
Research Institute for Farm Animal Biology (FBN)
Institute of Nutritional Physiology "Oskar Kellner"
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Institute of Nutritional Physiology "Oskar Kellner"
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- insects as farm animals for the utilization of residuals and by-products
- nutrient sensing
- energy efficiency
- metabolism
- adipokines
- fatty acids
- metabolic signalling pathways
- bioactive food ingredients
Curriculum Vitae
- 2013–present: Senior Scientist, Research Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Nutritional Physiology 'Oskar Kellner'
- 2013–present: Private Lecturer at the University of Bonn
- 2013: Habilitation (Physiology) at the University of Bonn
- 2002–2012: Senior Scientist at the University of Bonn, Institute of Animal Science, Physiology and Hygiene Unit
- Doctorate at the University of Hannover; Thesis at the Friedrich-Loeffler Institute, Federal Research Institute of Animal Health, Institute of Farm Animal Genetics, Department of Functional Genomics and Bioregulation, formerly Federal Agricultural Research Center (FAL) in Mariensee
- Studies in Biology at the University of Hannover; Diploma thesis at the Federal Agricultural Research Center (FAL) in Mariensee
Teaching
- Physiology and anatomy
Publications
Kopp, C.; Hosseini, A.; Singh, S. P.; Regenhard, P.; Khalilvandi-Behroozyar, H.; Sauerwein, H.; Mielenz, M. (2014):
Nicotinic acid increases adiponectin secretion from differentiated bovine preadipocytes through G-protein coupled receptor signaling. Int J Mol Sci 15: 21401-21418
https://dx.doi.org/10.3390/ijms151121401
Singh, S. P.; Häussler, S.; Heinz, J. F. L.; Akter, H.S.; Saremi, B.; Müller, U.; Rehage, J.; Dänicke, S.; Mielenz, M.; Sauerwein, H. (2014):
Lactation driven dynamics of adiponectin supply from different fat depots to circulation in cows. DOMEST ANIM ENDOCRIN 47: 35-46
https://dx.doi.org/10.1016/j.domaniend.2013.12.001
Singh, S. P.; Häussler, S.; Heinz, J. F. L.; Saremi, B.; Mielenz, B.; Rehage, J.; Dänicke, S.; Mielenz, M.; Sauerwein, H. (2014):
Supplementation with conjugated linoleic acids extends the adiponectin deficit during early lactation in dairy cows. Gen Comp Endocr 198: 13-21
https://dx.doi.org/10.1016/j.ygcen.2013.12.008
Friedrichs, P.; Saremi, B.; Winand, S.; Rehage, J.; Dänicke, S.; Sauerwein, H.; Mielenz, M. (2014):
Energy and metabolic sensing G protein-coupled receptors during lactation-induced changes in energy balance. DOMEST ANIM ENDOCRIN 48: 33-41
https://dx.doi.org/10.1016/j.domaniend.2014.01.005
Kopp, C.; Singh, S. P.; Regenhard, P.; Müller, U.; Sauerwein, H.; Mielenz, M. (2014):
Trans-cinnamic acid increases adiponectin and the phosphorylation of AMP-activated protein kinase through G-protein-coupled receptor signaling in 3T3-L1 adipocytes. Int J Mol Sci 15 (2): 2906-2915
https://dx.doi.org/10.3390/ijms15022906
Saremi, B.; Winand, S.; Friedrichs, P.; Kinoshita, A.; Rehage, J.; Dänicke, S.; Häussler, S.; Breves, G.; Mielenz, M.; Sauerwein, H. (2014):
Longitudinal profiling of the tissue-specific expression of genes related with insulin sensitivity in dairy cows during lactation focusing on different fat depots. Plos One 9 (1): 1-15
https://dx.doi.org/10.1371/journal.pone.0086211
Mielenz, M. (2013):
Role of adipose tissue in metabolic regulation of farmed animals. Habilitationsschrift, Rheinische Friedrich-Wilhelms-Universität Bonn: 1-161
Saremi, B.; Mielenz, M.; Rahmann, M. M.; Hosseini, A.; Kopp, C.; Dänicke, S.; Ceciliani, F.; Sauerwein, H. (2013):
Hepatic and extrahepatic expression of serum amyloid A3 during lactation in dairy cows. J Dairy Sci 96 (11): 6944-6954
https://dx.doi.org/10.3168/jds.2012-6495
Sauerwein, H.; Saremi, B.; Pappritz, J.; von Soosten, D.; Meyer, U.; Dänicke, S.; Mielenz, M. (2013):
Aquaporin-7 mRNA in adipose depots of primiparous and pluriparous dairy cows: long-term physiological and conjugated linoleic acid-induced changes. J Dairy Sci 96 (7): 4508-4513
https://dx.doi.org/10.3168/jds.2012-6363
Mielenz, M.; Mielenz, B.; Singh, S. P.; Kopp, C.; Heinz, J.; Häussler, S.; Sauerwein, H. (2013):
Development, validation, and pilot application of a semiquantitative Western blot analysis and an ELISA for bovine adiponectin. DOMEST ANIM ENDOCRIN 44 (3): 121-130
https://dx.doi.org/10.1016/j.domaniend.2012.10.004
Mielenz, M.; Kuhla, B.; Hammon, H. M. (2013):
Abundance of adiponectin system and G-protein coupled receptor GPR109A mRNA in adipose tissue and liver of F2 offspring cows of Charolais x German Holstein crosses that differ in body fat accumulation. J Dairy Sci 96 (1): 278-289
https://dx.doi.org/10.3168/jds.2012-5816