Prof. Dr. rer. nat. Klaus Wimmers

+49 38208 68-602
Research Institute for Farm Animal Biology (FBN)
Director
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

Research interests

  • inheritance and expression of traits related to productive adaptability and resilience in livestock
  • Trait-associated variation at the molecular levels of the genotype-phenotype map
  • Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

  • since 2016: director of the Leibniz-Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
  • 2008-2016: adjunct Professor, University of Bonn
  • 2004-2016: head of Institute for Genome Biology of the Leibniz-Institute for Farm Animal Biology (FBN)
  • 2002: habilitation in Animal Breeding and Genetics, University of Bonn
    1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
  • 1994: doctorate (Dr. rer. nat.)
  • 1990-1996: research fellow at the Institute of Animal production, TU Berlin
  • 1989: Study of veterinary science, FU Berlin

Teaching

  • Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Transient shifts of incubation temperature reveal immediate and long-term transcriptional response in chicken breast muscle underpinning resilience and phenotypic plasticity. Plos One 11 (9): e0162485, 1-17
https://dx.doi.org/10.1371/journal.pone.0162485
Liu, X.; Trakooljul, N.; Hadlich, F.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2016):
MicroRNA-mRNA regulatory networking fine-tunes the porcine muscle fiber type, muscular mitochondrial respiratory and metabolic enzyme activities. BMC Genomics 17: 531, 1-14
https://dx.doi.org/10.1186/s12864-016-2850-8
Ponsuksili, S.; Reyer, H.; Trakooljul, N.; Muràni, E.; Wimmers, K. (2016):
Single- and Bayesian multi-marker genome-wide association for haematological parameters in pigs. Plos One 11 (7): e0159212, 1-14
https://dx.doi.org/10.1371/journal.pone.0159212
Muràni, E.; Ponsuksili, S.; Jaeger, A.; Görres, A.; Tuchscherer, A.; Wimmers, K. (2016):
A naturally hypersensitive glucocorticoid receptor elicits a compensatory reduction of hypothalamus-pituitary-adrenal axis activity early in ontogeny. Open Biol 6 (7): 150193, 1-11
https://dx.doi.org/10.1098/rsob.150193
Naraballobh, W; Trakooljul, N.; Muràni, E.; Brunner, R. M.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2016):
Immediate and long-term transcriptional response of hind muscle tissue to transient variation of incubation temperature in broilers. BMC Genomics 17: 323, 1-13
https://dx.doi.org/10.1186/s12864-016-2671-9
Brade, W.; Wimmers, K. (2016):
Methan-Minderungspotenziale bei Wiederkäuern. Ber Landwirtsch 94 (1): 1-21
https://dx.doi.org/10.12767/buel.v94i1.104.g233
Liu, X.; Trakooljul, N.; Muràni, E.; Krischek, C.; Schellander, K.; Wicke, M.; Wimmers, K.; Ponsuksili, S. (2016):
Molecular changes in mitochondrial respiratory activity and metabolic enzyme activity in muscle of four pig breeds with distinct metabolic types. J Bioenerg Biomembr 48 (1): 55-65
https://dx.doi.org/10.1007/s10863-015-9639-3
Reyer, H.; Ponsuksili, S.; Kanitz, E.; Pöhland, R.; Wimmers, K.; Muràni, E. (2016):
A natural mutation in helix 5 of the ligand binding domain of glucocorticoid receptor enhances receptor-ligand interaction. Plos One 11 (10): e0164628, 1-15
https://dx.doi.org/10.1371/journal.pone.0164628
Borowska, A.; Reyer, H.; Wimmers, K.; Varley, P. F.; Szwaczkowski, T. (2016):
Detection of SNP effects on feed conversion ratio in pigs based on entropy approach. Acta fytotechn zootechn 19 (3): 103-105
https://dx.doi.org/10.15414/afz.2016.19.03.103-105
Graczyk, M.; Reyer, H.; Wimmers, K.; Hawken, R.; Szwaczkowski, T. (2016):
The search for SNPs and genes associated with the feed conversion ratio using entropy analysis. Acta fytotechn zootechn 19 (3): 93-95
https://dx.doi.org/10.15414/afz.2016.19.03.93-95
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Haack, F.; Muràni, E.; Wimmers, K. (2016):
Genetically regulated hepatic transcripts and pathways orchestrate haematological, biochemical and body composition traits. Sci Rep-UK 6: 39614, 1-13
https://dx.doi.org/10.1038/srep39614
Zinovieva, N. A.; Dotsev, A. V.; Sermyagin, A. A.; Wimmers, K.; Reyer, H.; Sölkner, J.; Deniskova, T.E.; Brem, G. (2016):
[Study of genetic diversity and population structure of five Russian cattle breeds using whole-genome SNP analysis - russ.]. Selskokhoziaĭstvennaia Biol 51 (6): 788-800
https://dx.doi.org/10.15389/agrobiology.2016.6.788rus
Wolf, P.; Borgelt, L.; Polley, C.; Vollmar, B.; Oster, M.; Wimmers, K. (2016):
Dichte und Zusammensetzung des Femurknochens von Absetzferkeln in Abhängigkeit zur P-Versorgung. In: Kongressband 2016 Rostock : Vorträge zum Generalthema: Anforderungen an die Verwertung von Reststoffen in der Landwirtschaft. (VDLUFA-Schriftenreihe , 73) VDLUFA-Verlag, Darmstadt (978-3-941273-23-8): 393-401
Wolf, P.; Borgelt, L.; Polley, C.; Vollmar, B.; Oster, M.; Wimmers, K. (2016):
Knochendichte und -zusammensetzung von Absetzferkeln bei unterschiedlicher P-Versorgung. In: Tierernährung für Tierärzte : im Focus: Die Fütterung von Schweinen , Hannover, 6. April 2016 (J. Kamphues ..., Hrsg.) DVG, Gießen (978-3-86345-309-1): 157-164
Dotsev, A. V.; Deniskova, T.E.; Okhlopkov, I. M.; Brem, G.; Wimmers, K.; Reyer, H.; Zinoviewa, N. (2016):
Внутривидовая дифференциация снежного барана с использованием полногеномного SNP анализа [Intraspecies differentiation of the snow sheep using whole-genome SNP analysis. - russ]. In: Снежный баран Якутии: генетическое разнообразие и пути сохранения генофонда [The snow sheep of Yakutia: genetic diversity and the ways of preservation of the gene pool. - russ.] (Bagirov V.A., Okhlopkov I.M., Zinov'eva N.A., Hrsg.) Izdatel'stvo VIZH im. L.K. Ernsta, Dubrovicy (978-5-902483-39-7): 171-185
Wimmers, K. (2016):
Die Bedeutung der Epigenetik in der Pflanzen- und Tierzüchtung. In: Die postgenomische Ära: die Renaissance des Phänotyps : 26. Hülsenberger Gespräche 2016, Hamburg, 07. bis 08. Juni 2016 (Schriftenreihe der H. Wilhelm Schaumann Stiftung) Hamburg: 59-63
Görres, A.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Analysis of non-synonymous SNPs of the porcine SERPINA6 gene as potential causal variants for a QTL affecting plasma cortisol levels on SSC7. Anim Genet 46 (3): 239-246
https://dx.doi.org/10.1111/age.12276
Oster, M.; Scheel, M.; Muràni, E.; Ponsuksili, S.; Zebunke, M.; Puppe, B.; Wimmers, K. (2015):
The fight-or-flight response is associated with PBMC expression profiles related to immune defence and recovery in swine. Plos One 10 (3): e0120153, 1-15
https://dx.doi.org/10.1371/journal.pone.0120153
Jaeger, A.; Bardehle, D.; Oster, M.; Günther, J.; Muràni, E.; Ponsuksili, S.; Wimmers, K.; Kemper, N. (2015):
Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro. Vet Res 46: 50, 1-18
https://dx.doi.org/10.1186/s13567-015-0178-z
Jaeger, A.; Fritschka, S.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Identification and functional characterization of cis-regulatory elements controlling expression of the porcine ADRB2 gene. Int J Biol Sci 11 (9): 1006-1015
https://dx.doi.org/10.7150/ijbs.12456