Prof. Dr. rer. nat. habil. Klaus Wimmers
Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Methling, K.; Lalk, M.; Murani, E.; Wimmers, K. (2019):
Genetic regulation of liver metabolites and transcripts linking to biochemical-llinical parameters. Front Genet 10: 348, 1-15
https://doi.org/10.3389/fgene.2019.00348
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
https://doi.org/10.1186/s12864-019-5880-1
Gley, K.; Murani, E.; Haack, F.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Haplotypes of coping behavior associated QTL regions reveal distinct transcript profiles in amygdala and hippocampus. Behav Brain Res 372: 112038, 1-13
https://doi.org/10.1016/j.bbr.2019.112038
Sajjanar, B.; Trakooljul, N.; Wimmers, K.; Ponsuksili, S. (2019):
DNA methylation analysis of porcine mammary epithelial cells reveals differentially methylated loci associated with immune response against Escherichia coli challenge. BMC Genomics 20: 623, 1-15
https://doi.org/10.1186/s12864-019-5976-7
Sajjanar, B.; Siengdee, P.; Trakooljul, N.; Liu, X; Kalbe, C.; Wimmers, K.; Ponsuksili, S. (2019):
Cross-talk between energy metabolism and epigenetics during temperature stress response in C2C12 myoblasts. Int J Hyperther 36 (1): 776-784
https://doi.org/10.1080/02656736.2019.1639834
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
https://doi.org/10.1080/15476286.2019.1657743
Gley, K.; Muráni, E.; Trakooljul, N.; Zebunke, M.; Puppe, B.; Wimmers, K.; Ponsuksili, S. (2019):
Transcriptome profiles of hypothalamus and adrenal gland linked to haplotype related to coping behavior in pigs. Sci Rep-UK 9: 13038, 1-14
https://doi.org/10.1038/s41598-019-49521-2
Muráni, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2019):
Transcriptome responses to dexamethasone depending on dose and glucocorticoid receptor sensitivity in the liver. Front Genet 10: 559, 1-12
https://doi.org/10.3389/fgene.2019.00559
Li, Z.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A.; Metges, C. C.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2019):
Kinetics of physiological and behavioural responses in endotoxemic pigs with or without dexamethasone treatment. Int J Mol Sci 20 (6): 1393, 1-15
https://doi.org/10.3390/ijms20061393
Gerlinger, Ch.; Oster, M.; Borgelt, L.; Reyer, H.; Muráni, E.; Ponsuksili, S.; Polley, C.; Vollmar, B.; Reichel, M.; Wolf, P; Wimmers, K. (2019):
Physiological and transcriptional responses in weaned piglets fed diets with varying phosphorus and calcium levels. Nutrients 11 (2): 436, 1-15
https://doi.org/10.3390/nu11020436
Horodyska, J.; Hamill, R.; Reyer, H.; Trakooljul, N.; Lawlor, P. G.; McCormack, U. M.; Wimmers, K. (2019):
RNA-seq of liver from pigs divergent in feed efficiency highlights shifts in macronutrient metabolism, hepatic growth and immune response. Front Genet 10: 117, 1-11
https://doi.org/10.3389/fgene.2019.00117
Mebratie, W.; Reyer, H.; Wimmers, K.; Bovenhuis, H.; Jensen, J. (2019):
Genome wide association study of body weight and feed efficiency traits in a commercial broiler chicken population, a re-visitation. Sci Rep-UK 9: 922, 1-10
https://doi.org/10.1038/s41598-018-37216-z
Horodyska, J.; Reyer, H.; Wimmers, K.; Trakooljul, N.; Lawlor, P. G.; Hamill, R. (2019):
Transcriptome analysis of adipose tissue from pigs divergent in feed efficiency reveals alteration in gene networks related to adipose growth, lipid metabolism, extracellular matrix and immune response. Mol Genet genomics 294: 395-408
https://doi.org/10.1007/s00438-018-1515-5
Engelke, S. W.; Daş, G.; Derno, M.; Tuchscherer, A.; Wimmers, K.; Rychlik, M.; Kienberger, H.; Berg, W.; Kuhla, B.; Metges, C. C. (2019):
Methane prediction based on individual or groups of milk fatty acids for dairy cows fed rations with or without linseed. J Dairy Sci 102 (2): 1788-1802
https://doi.org/10.3168/jds.2018-14911
Suliman, Y.; Becker, D.; Wimmers, K. (2018):
Implication of transcriptome profiling of spermatozoa for stallion fertility. Reprod Fert Develop 30 (8): 1087-1098
https://doi.org/10.1071/RD17188
Naraballobh, W; Trakooljul, N.; Muráni, E.; Krischek, C.; Janisch, S.; Wicke, M.; Ponsuksili, S.; Wimmers, K. (2018):
miRNAs regulate acute transcriptional changes in broiler embryos in response to modification of incubation temperature. Sci Rep-UK 8: 11371, 1-12
https://doi.org/10.1038/s41598-018-29316-7
Reyer, H.; Metzler-Zebeli, B.U.; Trakooljul, N.; Oster, M.; Muráni, E.; Ponsuksili, S.; Hadlich, F.; Wimmers, K. (2018):
Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens. Sci Rep-UK 8: 12903, 1-9
https://doi.org/10.1038/s41598-018-31072-7
Kharzinova, V. R.; Dotsev, A. V.; Deniskova, T.E.; Fedorov, V.; Layshev, K.; Romanenko, T.; Okhlopkov, I. M.; Wimmers, K.; Reyer, H.; Brem, G.; Zinovieva, N. A. (2018):
Genetic diversity and population structure of domestic and wild reindeer (Rangifer tarandus L. 1758): A novel approach using BovineHD BeadChip. Plos One 13 (11): e0207944
https://doi.org/10.1371/journal.pone.0207944
Horodyska, J.; Wimmers, K.; Reyer, H.; Trakooljul, N.; Mullen, A.; Lawlor, P. G.; Hamill, R. (2018):
RNA-seq of muscle from pigs divergent in feed efficiency and product quality identifies differences in immune response, growth, and macronutrient and connective tissue metabolism. BMC Genomics 19: 791, 1-18
https://doi.org/10.1186/s12864-018-5175-y
Nossol, C.; Landgraf, P.; Kahlert, S.; Oster, M.; ISermann, B.; Dieterich, D; Wimmers, K.; Dänicke, S.; Rothkötter, H.-J. (2018):
Deoxynivalenol affects cell metabolism and increases protein biosynthesis in intestinal porcine epithelial cells (IPEC-J2): DON increases protein biosynthesis. Toxins 10 (11): 464, 1-26
https://doi.org/10.3390/toxins10110464