Prof. Dr. rer. nat. habil. Klaus Wimmers
Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Chen, Cai; Zheng, Y.; Wang, Mengli; Murani, E.; D´Allesandro, E.; Moawad, A.; Wang, XY.; Wimmers, K.; Song, C. (2021):
SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor. Animals-Basel 11 (7): 1871, 1-13
https://doi.org/10.3390/ani11071871
Wang, XY.; Chen, J.; Murani, E.; D´Allesandro, E.; An, Y.; Chen, C.; Li, S.; Galeano, G.; Wimmers, K.; Song, C. (2021):
A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1. Mobile DNA-UK 12 (1): 20, 1-13
https://doi.org/10.1186/s13100-021-00248-w
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Ponsuksili, S.; Oster, M.; Reyer, H.; Hadlich, F.; Trakooljul, N.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2021):
Genetic regulation and heritability of miRNA and mRNA expression link to phosphorus utilization and gut microbiome. Open Biol 11 (2): 200182, 1-11
https://doi.org/10.1098/rsob.200182
Ponsuksili, S.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Genetic background and production periods shape the microRNA profiles of the gut in laying hens. Genomics 113 (4): 1790-1801
https://doi.org/10.1016/j.ygeno.2021.04.018
Iqbal, M. A.; Ali, A.; Hadlich, F.; Oster, M.; Reyer, H.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2021):
Dietary phosphorus and calcium in feed afects miRNA profles and their mRNA targets in jejunum of two strains of laying hens. Sci Rep-UK 11: 13534, 1-19
https://doi.org/10.1038/s41598-021-92932-3
Abu Risha, M.; Ali, A.; Siengdee, P.; Trakooljul, N.; Haack, F.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2021):
Wnt signaling related transcripts and their relationship to energy metabolism in C2C12 myoblasts under temperature stress. PeerJ 9: e11625, 1-20
https://doi.org/10.7717/peerj.11625
Abu Risha, M.; Siengdee, P.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2021):
PUFA Treatment Affects C2C12 Myocyte Differentiation, Myogenesis Related Genes and Energy Metabolism. Genes-Basel 12 (2): 192,1-18
https://doi.org/10.3390/genes12020192
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes. Genes-Basel 12 (8): 1264, 1-16
https://doi.org/10.3390/genes12081264
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
Prenatal Skeletal Muscle Transcriptome Analysis Reveals Novel MicroRNA-mRNA Networks Associated with Intrauterine Growth Restriction in Pigs. Cells-Basel 10 (5): 1007, 1-21
https://doi.org/10.3390/cells10051007
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Murani, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Jejunal transcriptomic profiling of two layer strains throughout the entire production period. Sci Rep-UK 11: 20086, 1-11
https://doi.org/10.1038/s41598-021-99566-5
Dänicke, S.; Heymann, A.-K.; Oster, M.; Wimmers, K.; Tesch, T.; Bannert, E.; Bühler, S.; Kersten, S.; Frahm, J.; Kluess, J.; Kahlert, S.; Rothkötter, H.-J.; Billenkamp, F. (2021):
Does chronic dietary exposure to the mycotoxin deoxynivalenol affect the porcine hepatic transcriptome when an acute-phase response is initiated through first or second-pass LPS challenge of the liver?. Innate Immun-London 27 (5): 388-408
https://doi.org/10.1177/17534259211030563
Honerlagen, H.; Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Kuhla, B.; Reinsch, N.; Wimmers, K. (2021):
Identification of Genomic Regions Influencing N-Metabolism and N-Excretion in Lactating Holstein- Friesians. Front Genet 12: 699550, 1-12
https://doi.org/10.3389/fgene.2021.699550
Deniskova, T.E.; Dotsev, A. V.; Selionova, M. I.; Reyer, H.; Sölkner, J.; Fornara, M. S.; Aybazov, A.-M. M.; Wimmers, K.; Brem, G.; Zinovieva, N. A. (2021):
SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats. Front Genet 12: 708740, 1-16
https://doi.org/10.3389/fgene.2021.708740
Abousoliman, I.; Reyer, H.; Oster, M.; Murani, E.; Mohamed, I.; Wimmers, K. (2021):
Genome-Wide SNP Analysis for Milk Performance Traits in Indigenous Sheep: A Case Study in the Egyptian Barki Sheep. Animal 11 (6): 1-9
https://doi.org/10.3390/ani11061671
Reyer, H.; Sjöberg, P. J. R.; Oster, M.; Wubuli, A.; Murani, E.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2021):
Mineral Phosphorus Supply in Piglets Impacts the Microbial Composition and Phytate Utilization in the Large Intestine. Microorganisms 9 (9): 1197, 1-10
https://doi.org/10.3390/microorganisms9061197
Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Omotoso, A. O.; Iqbal, M. A.; Murani, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Transcriptional responses in jejunum of two layer chicken strains following variations in dietary calcium and phosphorus levels. BMC Genomics 22: 485, 1-12
https://doi.org/10.1186/s12864-021-07814-9
Oster, M.; Reyer, H.; Keiler, J.; Ball, E.; Mulvenna, C.; Ponsuksili, S.; Wimmers, K. (2021):
Comfrey (Symphytum spp.) as a feed supplement in pig nutrition contributes to regional resource cycles. Sci Total Environ 796: 148988, 1-11
https://doi.org/10.1016/j.scitotenv.2021.148988
Li, Z.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K.; Murani, E. (2021):
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. Virulence 12 (1): 1808-1824
https://doi.org/10.1080/21505594.2021.1948276
Walz, C.; Brenmoehl, J.; Trakooljul, N.; Noce, A.; Caffier, C.; Ohde, D.; Langhammer, M.; Wimmers, K.; Ponsuksili, S.; Hoeflich, A. (2021):
Control of Protein and Energy Metabolism in the Pituitary Gland in Response to Three-Week Running Training in Adult Male Mice
. Cells-Basel 10 (4): 736, 1-20
https://doi.org/10.3390/cells10040736