Prof. Dr. rer. nat. habil. Klaus Wimmers
Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Mulvenna, C.; McCormack, U. M.; Magowan, E.; McKillen, J.; Bedford, M. R.; Walk, C.; Oster, M.; Reyer, H.; Wimmers, K.; Fornara, D.; Ball, E. (2022):
The Growth Performance, Nutrient Digestibility, Gut Bacteria and Bone Strength of Broilers Offered Alternative, Sustainable Diets Varying in Nutrient Specification and Phytase Dose
Animals 12 (13): 1669, 1-19
https://doi.org/10.3390/ani12131669
Fornara, D.; Ball, E.; Mulvenna, C.; Reyer, H.; Oster, M.; Wimmers, K.; Poulsen, H.; Rosemarin, A. (2022):
Soil and Plant Responses to Phosphorus Inputs from Different Phytase-Associated Animal Diets
Agronomy 12 (1): 130, 1-16
https://doi.org/10.3390/agronomy12010130
Diehl, B.; Oster, M.; Vernunft, A.; Wimmers, K.; Bostedt, H. (2022):
Intrinsic challenges of neonatal adaptation in swine
Archives Animal Breeding 65 (4): 427-438
https://doi.org/10.5194/aab-65-427-2022
Li, Z.; Hadlich, F.; Wimmers, K.; Murani, E. (2022):
Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs
Frontiers in Immunology 13: 976454, 1-16
https://doi.org/10.3389/fimmu.2022.976454
Adzigbli, L.; Sokolov, E. P.; Wimmers, K.; Sokolova, I. M.; Ponsuksili, S. (2022):
Effects of hypoxia and reoxygenation on mitochondrial functions and transcriptional profiles of isolated brain and muscle porcine cells
Scientific Reports 12: 19881, 1-17
https://doi.org/10.1038/s41598-022-24386-0
Iqbal, M. A.; Reyer, H.; Oster, M.; Hadlich, F.; Trakooljul, N.; Perdomo-Sabogal, A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2022):
Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens
Frontiers in Genetics 13: 858232, 1-20
https://doi.org/10.3389/fgene.2022.858232
Sarais, F.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2022):
tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research
Non-Coding RNA 8 (3): 37, 1-19
https://doi.org/10.3390/ncrna8030037
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity
Scientific Reports 12: 16293, 1-13
https://doi.org/10.1038/s41598-022-20682-x
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight
Biology of Sex Differences 13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex Open Access
Siriluck Wimmers,
Eduard Muráni,
Muhammad Arsalan Iqbal,
Beate Fuchs,
Christina Galuska,
Henry Reyer,
Michael Oster,
Klaus Wimmers
Open Biology 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Prahl, M. C.; Müller, C. B. M.; Albrecht, D.; Koch, F.; Wimmers, K.; Kuhla, B. (2022):
Hepatic urea, creatinine and uric acid metabolism in dairy cows with divergent milk urea concentrations
Scientific Reports 12: 17593, 1-1
https://doi.org/10.1038/s41598-022-22536-y
Abu Risha, M.; Ali, A.; Siengdee, P.; Trakooljul, N.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2022):
Insights into molecular pathways and fatty acid membrane composition during the temperature stress response in the murine C2C12 cell model
Science of The Total Environment 807 (3): 151019, 1-13
https://doi.org/10.1016/j.scitotenv.2021.151019
Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain Transcriptome Responses to Dexamethasone Depending on Dose and Sex Reveal Factors Contributing to Sex-Specific Vulnerability to Stress-Induced Disorders
Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Hosseini, S.; Trakooljul, N.; Hirschfeld, M.; Wimmers, K.; Simianer, H.; Tetens, J.; Sharifi, R.; Brenig, B. (2022):
Epigenetic Regulation of Phenotypic Sexual Plasticity Inducing Skewed Sex Ratio in Zebrafish
Frontiers in Cell and Developmental Biology 10: 880779, 1-21
https://doi.org/10.3389/fcell.2022.880779
Ovilo, C.; Trakooljul, N.; Nunez, Y; Hadlich, F.; Murani, E.; Ayuso, M; García-Contreras, C; Vázquez-Gómez, M.; Rey, A.; Garcia, F; García-Casco, J.; Lopez-Bote, C.; Isabel, B.; Gonzales-Bulnes, A.; Wimmers, K.; Munoz, J. (2022):
SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs
Scientific Reports 12: 16361, 1-16
https://doi.org/10.1038/s41598-022-20817-0
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418
Pan, Z.; Yao, Y.; Hongwei, Y.; Cai, Z.; Wang, Y.; Bai, L.; Kern, C.; Halstead, M.; Chanthavixay, G.; Trakooljul, N.; Wimmers, K.; Sahana, G.; Su, G.; Lund, M. S.; Fredholm, M.; Karlskov-Mortensen, P.; Ernst, C. W.; Ross, P.; Tuggle, C. K.; Fang, L.; Zhou, H. (2021):
Pig genome functional annotation enhances the biological interpretation of complex traits and human disease. Nat Commun 12: 5848, 1-15
https://doi.org/10.1038/s41467-021-26153-7
Deniskova, T.E.; Petrov, S. N.; Sermyagin, A. A.; Dotsev, A. V.; Fornara, M. S.; Reyer, H.; Wimmers, K.; Bagirov, V.A.; Brem, G.; Zinovieva, N. A. (2021):
A search for genomic variants associated with body weight in sheep based on high density SNP genotypes analysis. Agricultural Biology 56 (2): 279-291
https://doi.org/10.15389/agrobiology.2021.2.279eng
Zinovieva, N. A.; Sheiko, I. P.; Dotsev, A. V.; Sheiko, R. I.; Mikhailova, M. E.; Sermyagin, A. A.; Abdelmanova, A. S.; Kharzinova, V. R.; Reyer, H.; Wimmers, K.; Sölkner, J.; Pleshanov, N. V.; Brem, G. (2021):
Genome-wide SNP analysis clearly distinguished the Belarusian Red cattle from other European cattle breeds. Anim Genet 52 (5): 720-724
https://doi.org/10.1111/age.13102