Prof. Dr. rer. nat. Klaus Wimmers
+49 38208 68-602
Research Institute for Farm Animal Biology (FBN)
Director
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Director
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Leibniz-Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Leibniz-Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER
13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
Siriluck Wimmers,
Michael Oster,
Henry Reyer,
Fabio Sarais,
Christina Galuska,
Beate Fuchs,
Muhammad Arsalan Iqbal,
Eduard Muráni,
Klaus Wimmers
https://doi.org/10.1098/rsob.220151
Prahl, M.; Müller, C. B. M.; Albrecht, D.; Koch, F.; Wimmers, K.; Kuhla, B. (2022):
Hepatic urea, creatinine and uric acid metabolism in dairy cows with divergent milk urea concentrations. Sci Rep-UK 12: 17593, 1-14
https://doi.org/10.1038/s41598-022-22536-y
Vernunft, A.; Gladbach, C.; Oster, M.; Bostedt, H.; Wimmers, K. (2022):
Neue Erkenntnisse zur Vitalität und Verlusten bei Saugferkeln bei freier Abferkelung. In: 26. Mitteldeutscher Schweineworkshop in Bernburg, "Schweineproduktion und Schweinegesundheit - Was uns heute bewegt?!" (Hochschule Anhalt, Fachbereich Landwirtschaft, Prof. Dr. Heiko Scholz, Hrsg.) Hochschule Anhalt, Dessau (978-3-96057-134-6): 33-35"
Abu Risha, M.; Ali, A.; Siengdee, P.; Trakooljul, N.; Dannenberger, D.; Wimmers, K.; Ponsuksili, S. (2022):
Insights into molecular pathways and fatty acid membrane composition during the temperature stress response in the murine C2C12 cell model. Sci Total Environ 807 (3): 151019, 1-13
https://doi.org/10.1016/j.scitotenv.2021.151019
Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Hosseini, S.; Trakooljul, N.; Hirschfeld, M.; Wimmers, K.; Simianer, H.; Tetens, J.; Sharifi, R.; Brenig, B. (2022):
Epigenetic Regulation of Phenotypic Sexual Plasticity Inducing Skewed Sex Ratio in Zebrafish. Front Cell Dev Biol 10: 880779, 1-21
https://doi.org/10.3389/fcell.2022.880779
Ovilo, C.; Trakooljul, N.; Nunez, Y; Hadlich, F.; Murani, E.; Ayuso, M; García-Contreras, C; Vázquez-Gómez, M.; Rey, A.; Garcia, F; García-Casco, J.; Lopez-Bote, C.; Isabel, B.; Gonzales-Bulnes, A.; Wimmers, K.; Munoz, J. (2022):
SNP discovery and association study for growth, fatness and meat quality traits in Iberian crossbred pigs. Sci Rep-UK 12: 16361, 1-16
https://doi.org/10.1038/s41598-022-20817-0
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
https://doi.org/10.1016/j.gpb.2020.06.007
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418
Pan, Z.; Yao, Y.; Hongwei, Y.; Cai, Z.; Wang, Y.; Bai, L.; Kern, C.; Halstead, M.; Chanthavixay, G.; Trakooljul, N.; Wimmers, K.; Sahana, G.; Su, G.; Lund, M. S.; Fredholm, M.; Karlskov-Mortensen, P.; Ernst, C. W.; Ross, P.; Tuggle, C. K.; Fang, L.; Zhou, H. (2021):
Pig genome functional annotation enhances the biological interpretation of complex traits and human disease. Nat Commun 12: 5848, 1-15
https://doi.org/10.1038/s41467-021-26153-7
Deniskova, T.E.; Petrov, S. N.; Sermyagin, A. A.; Dotsev, A. V.; Fornara, M. S.; Reyer, H.; Wimmers, K.; Bagirov, V.A.; Brem, G.; Zinovieva, N. A. (2021):
A search for genomic variants associated with body weight in sheep based on high density SNP genotypes analysis. Agricultural Biology 56 (2): 279-291
https://doi.org/10.15389/agrobiology.2021.2.279eng
Zinovieva, N. A.; Sheiko, I. P.; Dotsev, A. V.; Sheiko, R. I.; Mikhailova, M. E.; Sermyagin, A. A.; Abdelmanova, A. S.; Kharzinova, V. R.; Reyer, H.; Wimmers, K.; Sölkner, J.; Pleshanov, N. V.; Brem, G. (2021):
Genome-wide SNP analysis clearly distinguished the Belarusian Red cattle from other European cattle breeds. Anim Genet 52 (5): 720-724
https://doi.org/10.1111/age.13102
Abousoliman, I.; Reyer, H.; Oster, M.; Murani, E.; Mohamed, I.; Wimmers, K. (2021):
Genome-Wide Analysis for Early Growth-Related Traits of the Locally Adapted Egyptian Barki Sheep. Genes-Basel 12 (8): 1243, 1-10
https://doi.org/10.3390/genes12081243
Chen, C.; D´Allesandro, E.; Murani, E.; Zheng, Y.; Giosa, D.; Yang, R; Wang, XY.; Gao, B; Li, S.; Wimmers, K.; Song, C. (2021):
SINE jumping contributes to large-scale polymorphisms in the pig genomes. Mobile DNA-UK 12: 17, 1-17
https://doi.org/10.1186/s13100-021-00246-y
Chen, Cai; Zheng, Y.; Wang, Mengli; Murani, E.; D´Allesandro, E.; Moawad, A.; Wang, XY.; Wimmers, K.; Song, C. (2021):
SINE Insertion in the Intron of Pig GHR May Decrease Its Expression by Acting as a Repressor. Animals-Basel 11 (7): 1871, 1-13
https://doi.org/10.3390/ani11071871
Wang, XY.; Chen, J.; Murani, E.; D´Allesandro, E.; An, Y.; Chen, C.; Li, S.; Galeano, G.; Wimmers, K.; Song, C. (2021):
A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1. Mobile DNA-UK 12 (1): 20, 1-13
https://doi.org/10.1186/s13100-021-00248-w
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Ponsuksili, S.; Oster, M.; Reyer, H.; Hadlich, F.; Trakooljul, N.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2021):
Genetic regulation and heritability of miRNA and mRNA expression link to phosphorus utilization and gut microbiome. Open Biol 11 (2): 200182, 1-11
https://doi.org/10.1098/rsob.200182
Ponsuksili, S.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Genetic background and production periods shape the microRNA profiles of the gut in laying hens. Genomics 113 (4): 1790-1801
https://doi.org/10.1016/j.ygeno.2021.04.018