Prof. Dr. rer. nat. habil. Klaus Wimmers
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Ponsuksili, S.; Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2025):
DNA methylation in adipocyte differentiation of porcine mesenchymal stem cells and the impact of the donor metabolic type
Genomics 117 (3): 111050, 1-13
https://doi.org/10.1016/j.ygeno.2025.111050
Oster, M.; Gladbach, C. A.; Vernunft, A.; Reyer, H.; Otten, W.; Metges, C. C.; Muráni, E.; Ponsuksili, S.; Frölich, K.; Wimmers, K.; Bostedt, H. (2025):
Influence of genotype-environment interaction on stress parameters during spontaneous farrowing in modern and traditional pig breeds housed in crates and pens
Theriogenology 240: 117394, 1-11
https://doi.org/10.1016/j.theriogenology.2025.117394
Lickfett, H.; Oster, M.; Vernunft, A.; Reyer, H.; Görs, S.; Metges, C. C.; Bostedt, H.; Wimmers, K. (2025):
Influence of genotype and environment on piglet vitality and metabolic state during the suckling period of divergent birth weight classes
Animal 19 (4): 101460, 1-14
https://doi.org/10.1016/j.animal.2025.101460
Cavalleri, M.; Sciascia, Q. L.; Görs, S.; Vernunft, A.; Reyer, H.; Wimmers, K.; Zentek, J.; Kluess, J.; Dänicke, S.; Metges, C. C. (2025):
Measurement of Oro-Cecal Transit Time in LPS-Treated Pigs Fed High and Low Fiber Diets Using the Lactose-13C-Ureide Test in Breath and Saliva Samples
Journal of Agricultural and Food Chemistry 73 (17): 10304−10315
https://doi.org/10.1021/acs.jafc.5c00534
Reyer, H.; Mielenz, M.; Daş, G.; Metges, C. C.; Wimmers, K. (2025):
Microbial profiling of black soldier fly larvae reared on substrates supplemented with different mineral sources originating from phosphorus recycling technologies
Animal Microbiome 7: 14, 1-14
https://doi.org/10.1186/s42523-025-00380-5
Ponsuksili, S.; Hadlich, F.; Li, S.; Trakooljul, N.; Reyer, H.; Oster, M.; Abitew, Y. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages
Physiological Genomics 57 (3): 125-139
https://doi.org/10.1152/physiolgenomics.00063.2024
Muráni, E.; Trakooljul, N.; Hadlich, F.; Wimmers, K. (2025):
Transcriptional signature of a hypersensitive glucocorticoid receptor variant in the neuroendocrine system suggests enhanced vulnerability to brain disorders
Brain, Behavior and Immunity 124 (2): 335-346
https://doi.org/10.1016/j.bbi.2024.12.004
Ma, W.; Brenmoehl, J.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2025):
Dexamethasone has profound influence on the energy metabolism of porcine blood leukocytes and prevents the LPS-induced glycolytic switch
Frontiers in Immunology 16: 1514061, 1-13
https://doi.org/10.3389/fimmu.2025.1514061
Sommerfeld, V.; Hanauska, A.; Huber, K.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):
Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens
Poultry Science 104 (1): 104545, 1-30
https://doi.org/10.1016/j.psj.2024.104545
Sommerfeld, V.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Huber, H.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):
Effects of feeding diets without mineral P supplement on intestinal phytate degradation, blood concentrations of Ca and P, and excretion of Ca and P in two laying hen strains before and after onset of laying activity
Poultry Science 103 (12): 104407, 1-12
https://doi.org/10.1016/j.psj.2024.104407
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Metzler-Zebeli, B.; Wimmers, K. (2024):
Hepatic Transcriptomics of Broilers with Low and High Feed Conversion in Response to Caloric Restriction
Metabolites 14: 625, 1-13
https://doi.org/10.3390/metabo14110625
Honerlagen, H.; Reyer, H.; Wimmers, K. (2024):
Fundamental insights into the host genome - rumen microbiota - trait complex of cow-individual nitrogen (N) utilisation and N excretion
Züchtungskunde 96 (1), 34-42
Abitew, Y. A.; Reyer, H.; Hadlich, F.; Oster, M.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2024):
Transcriptional responses to diets without mineral phosphorus supplementation in the jejunum of two high-yielding laying hen strains
Poultry Science 103 (12): 104484, 1-11
https://doi.org/10.1016/j.psj.2024.104484
Reyer, H.; Honerlagen, H.; Oster, M.; Ponsuksili, S.; Kuhla, B.; Wimmers, K. (2024):
Multi-tissue gene expression profiling of cows with a genetic predisposition for low and high milk urea levels
Animal Biotechnology 35 (1): 2322542, 1-9
https://doi.org/10.1080/10495398.2024.2322542
Kalbfleisch, T. S.; McKay, S. D.; Murdoch, B. M.; Adelson, D. L.; Almansa-Villa, D.; Becker, G.; Beckett, L. M.; Benítez-Galeano, M. J.; Biase, F.; Casey, T.; Chuong, E.; Clark, E.; Clark, S.; Cockett, N.; Couldrey, C.; Davis, B. W.; Elsik, C. G.; Faraut, T.; Gao, Y.; Genet, C.; Grady, P.; Green, J.; Green, R.; Guan, D.; Hagen, D.; Hartley, G. A.; Heaton, M.; Hoyt, S. J.; Huang, W.; Jarvis, E.; Kalleberg, J.; Khatib, H.; Koepfi, K.-P.; Koltes, J.; Koren, S.; Kuehn, C.; Leeb, T.; Leonard, A.; Liu, G. E.; Low, W. Y.; McConnell, H.; McRae, K.; Miga, K.; Mousel, M.; Neibergs, H.; Olagunju, T.; Pennell, M.; Petry, B.; Pewsner, M.; Phillippy, A. M.; Pickett, B. D.; Pineda, P.; Potapova, T.; Rachagani, S.; Rhie, A.; Rijnkels, M.; Robic, A.; Osorio, N. R.; Safonova, Y.; Schettini, G.; Schnabel, R. D.; Natesh, N. S.; Stegemiller, N. R.; Storer, J.; Stothard, P.; Stull, C.; Tosser-Klopp, G.; Traglia, G. M.; Tuggle, C. K.; Tassell, C. P. Van; Watson, C.; Weikard, R.; Wimmers, K.; Xie, S.; Yang, L.; Smith, T. P. L.; O’Neil, R. J.; Rosen, B. D. (2024):
The Ruminant Telomere-to-Telomere (RT2T) Consortium
Nature Genetics 56: 1566-1573
https://www.nature.com/articles/s41588-024-01835-2
Ponsuksili, S.; Siengdee, P.; Li, S.; Kriangwanich, W.; Oster, M.; Reyer, H.; Wimmers, K. (2024):
Effect of metabolically divergent pig breeds and tissues on mesenchymal stem cell expression patterns during adipogenesis
BMC Genomics 25: 407, 1-15
https://doi.org/10.1186/s12864-024-10308-z
Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2024):
Dynamics of DNA methylation during osteogenic differentiation of porcinesynovial membrane mesenchymal stem cells from two metabolically distinctbreeds
Epigenetics 19 (1): 2375011, 1-15
https://doi.org/10.1080/15592294.2024.2375011
Koch, F.; Reyer, H.; Görs, S.; Hansen, C.; Wimmers, K; Kuhla, B. (2024):
Heat stress and feeding effects on the mucosa-associated and digesta microbiome and their relationship to plasma and digesta fluid metabolites in the jejunum of dairy cows
Journal of Dairy Science 107 (7): 5162-5177
https://doi.org/10.3168/jds.2023-24242
Hasan, M.; Reyer, H.; Oster, M.; Trakooljul, N.; Ponsuksili, S.; Magowan, E.; Fischer, D.-C.; Wimmers, K. (2024):
Exposure to artificial ultraviolet-B light mediates alterations on the hepatic transcriptome and vitamin D metabolism in pigs
The Journal of Steroid Biochemistry and Molecular Biology 236: 106428, 1-8
https://doi.org/10.1016/j.jsbmb.2023.106428
Reyer, H.; Abou-Soliman, I.; Schulze, M.; Henne, H.; Reinsch, N.; Schön, J.; Wimmers, K. (2024):
Genome-Wide Association Analysis of Semen Characteristics in Piétrain Boars
Genes 15 (3): 382, 1-12
https://doi.org/10.3390/genes15030382