Prof. Dr. rer. nat. Klaus Wimmers
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Leibniz-Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Leibniz-Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Maak, S.; Boettcher, D.; Tetens, J.; Swalve, H. H.; Wimmers, K.; Thaller, G. (2009):
Expression of microRNAs is not related to increased expression of ZDHHC9 in hind leg muscles of splay leg piglets. Mol Cell Probe 24 (1): 32-37
https://dx.doi.org/10.1016/j.mcp.2009.09.001
Metges, C. C.; Peters, M.; Sauerwein, H.; Ooster, A.; Ponsuksili, S.; Altmann, S.; Oster, M.; Rehfeldt, C.; Wimmers, K. (2009):
Fetal Programming: Mütterliche Ernährung und Merkmalsausprägung der Nachkommen beim Schwein. Genomexpress (1.09): 11-13
Tetzlaff, S.; Muràni, E.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2009):
Differential expression of growth factors and their receptors points out their involvement in the inverted teat defect in pigs. J Anim Sci 87 (11): 3451-3457
https://dx.doi.org/10.2527/jas.2008-1660
Tetzlaff, S.; Jonas, E; Phatsara, C.; Muràni, E.; Ponsuksili, S.; Schellander, K.; Wimmers, K. (2009):
Evidence for association of lymphoid enhancer-binding factor-1 (LEF1) with the number of functional and inverted teats in pigs. Cytogenet Genome Res 124 (2): 139-146
https://dx.doi.org/10.1159/000207521
Tetzlaff, S.; Chomdej, S.; Jonas, E; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schellander, K.; Wimmers, K. (2009):
Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs. J Anim Breed Genet 126 (3): 237-241
https://dx.doi.org/10.1111/j.1439-0388.2008.00781.x
Maak, S.; Boettcher, D.; Tetens, J.; Wensch-Dorendorf, M.; Nürnberg, G.; Wimmers, K.; Swalve, H. H.; Thaller, G. (2009):
Identification of candidate genes for congenital splay leg in piglets by alternative analysis of DNA microarray data. Int J Biol Sci 5 (4): 331-337
https://dx.doi.org/10.7150/ijbs.5.331
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Jonas, E; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2008):
Expression profiling of muscle reveals transcripts differentially expressed in muscle that affect water-holding capacity of pork. J Agr Food Chem 56 (21): 10311-10317
https://dx.doi.org/10.1021/jf800881y
Wimmers, K.; Ngu, N.T.; Jennen, D.; Tesfaye, D.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2008):
Relationship between myosin heavy chain isoform expression and muscling in several diverse pig breeds. J Anim Sci 86 (4): 795-803
https://dx.doi.org/10.2527/jas.2006-521
Wimmers, K. (2008):
14. Mitteldeutscher Schwein-Workshop, Kurzfassungen, Fruchtbarkeit im Sauenbestand, 16.5.-17.5.08, Bernburg. In: Stand und Perspektiven der Molekulargenetik beim Schwein - Karten-basierte und Funktions-orientierte Ansätze zur Identifizierung von Genen für funktionale Merkmale
(Hochschule Anhalt, Hrsg.) (14): 111-124
Wimmers, K.; Kumar, K.G.; Schellander, K.; Ponsuksili, S. (2008):
Porcine IL12A and IL12B gene mapping, variation and evidence of association with lytic complement and blood leucocyte proliferation traits. INT J IMMUNOGENET 35 (1): 75-85
https://dx.doi.org/10.1111/j.1744-313X.2007.00742.x
Ponsuksili, S.; Jonas, E; Muràni, E.; Phatsara, C.; Srikanchai, T.; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2008):
Trait correlated expression combined with expression QTL analysis reveals biological pathways and candidate genes affecting water holding capacity of muscle. BMC Genomics 9: 367
https://dx.doi.org/10.1186/1471-2164-9-367
Liu, G.; Kim, EJ; Jonas, E; Wimmers, K.; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Tholen, E.; Jüngst, H.; Tesfaye, D.; Ji Lan Chen, J.L; Schellander, K. (2008):
Combined line-cross and half-sib QTL analysis in Duroc-Pietrain population. Mamm Genome 19 (6): 429-438
https://dx.doi.org/10.1007/s00335-008-9132-y
Phatsara, C.; Jonas, E; Yammuen-art, S; Buschbell, K; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Wimmers, K. (2008):
Physiological interactions between the endocrine and immune systems shown in gene analysis in pigs. Developments in Biologicals 132: 161-167
Ponsuksili, S.; Muràni, E.; Wimmers, K. (2008):
Porcine genome-wide gene expression in response to tetanus toxoid vaccine. Developments in Biologicals 132: 185-195
Wimmers, K.; Jonas, E; Schreinemachers, H.-J.; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Phatsara, C. (2008):
Verification of chromosomal regions affecting the innate immunity in pigs using linkage mapping.. Developments in Biologicals 132: 279-286
Jonas, E; Schreinemachers, H.-J.; Kleinwächter, T.; Ün, G.; Oltmanns, I.; Tetzlaff, S.; Jennen, D.; Tesfaye, D.; Ponsuksili, S.; Muràni, E.; Jüngst, H.; Tholen, E.; Schellander, K.; Wimmers, K. (2008):
QTL for the heritable inverted teat defect in pigs. Mamm Genome 19 (2): 127-138
https://dx.doi.org/10.1007/s00335-007-9086-5
Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T. (2008):
Characterization of Dehydrodolichyl diphosphate synthase gene in rainbow trout (Oncorhynchus mykiss). Comp Biochem Biophys B 152 (3): 260-265
https://dx.doi.org/10.1016/j.cbpb.2008.12.003
Thumdee, P.; Ponsuksili, S.; Muràni, E.; Nganvongpanit, K.; Gehrig, B; Tesfaye, D.; Gilles, M.; Hoelker, M; Jennen, D.; Griese, J.; Schellander, K.; Wimmers, K. (2007):
Expression of the prion protein gene (PRNP) and cellular prion protein (PrPc) in cattle and sheep foetuses and maternal tissues during pregnancy. Gene Expression 13 (4-5): 283-297
https://doi.org/10.3727/000000006780666984
Wimmers, K. (2007):
Defektgene beim Schwein: Stand der molekulargenetischen Charakterisierung und Perspektiven. Zuchtungskunde 80: 35-42
Mörlein, D; Link, G; Muràni, E.; Wimmers, K.; Wicke, M. (2007):
Evaluation of three pig crossbreed types with respect to strategies to improve the meat quality: MHS genotype rather than crossbreed type influences drip loss. Arch Tierzucht 50 (6): 605-618