Prof. Dr. rer. nat. habil. Klaus Wimmers

Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

Research interests

  • inheritance and expression of traits related to productive adaptability and resilience in livestock
  • Trait-associated variation at the molecular levels of the genotype-phenotype map
  • Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

  • since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
  • 2008-2016: adjunct Professor, University of Bonn
  • 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
  • 2002: habilitation in Animal Breeding and Genetics, University of Bonn
    1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
  • 1994: doctorate (Dr. rer. nat.)
  • 1990-1996: research fellow at the Institute of Animal production, TU Berlin
  • 1989: Study of veterinary science, FU Berlin

Teaching

  • Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Muràni, E.; Ponsuksili, S.; D´Eath, R.; Turner, S.P.; Evans, G.; Foury, A.; Kurt, E.; Thölking, L.; Klont, R.; Mormède, P.; Wimmers, K. (2010):
Transcriptional profiling of the adrenal gland for the identification of genes and pathways associated with stress response and aggressive behaviour. In: 32th ISAG conference proceedings (International Society for Animal Genetics, Hrsg.): 108
Muràni, E.; Ponsuksili, S.; D´Eath, R.; Turner, S.P.; Kurt, E.; Evans, G.; Thölking, L.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2010):
Association of HPA axis-related genetic variation with stress reactivity and aggressive behaviour in pigs. BMC Genet 11 (74): 1-11
https://dx.doi.org/10.1186/1471-2156-11-74
Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kotterba, G.; Anders, E.; Wimmers, K.; Goldammer, T. (2010):
Molecular characterization of PRR13 and its tissue-specific expression in rainbow trout (Oncorhynchus mykiss). Fish Physiol Biochem 36 (4): 1271-1276
https://dx.doi.org/10.1007/s10695-010-9407-6
Maak, S.; Boettcher, D.; Komolka, K.; Tetens, J.; Wimmers, K.; Reinsch, N.; Swalve, H. H.; Thaller, G. (2010):
Exclusion of sequence polymorphisms in the porcine ITGA5 and MIR148B loci as causal variation for congenital splay leg in piglets. Anim Genet 41 (4): 447-448
https://dx.doi.org/10.1111/j.1365-2052.2010.02047.x
Srikanchai, T.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2010):
Association of ZYX polymorphisms with carcass and meat quality traits in commercial pigs. Meat Sci 84 (1): 159-164
https://dx.doi.org/10.1016/j.meatsci.2009.08.042
Muràni, E.; Ponsuksili, S.; Seyfert, H.-M.; Shi, X.; Wimmers, K. (2009):
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing. BMC Mol Biol 10 (96): 1-11
https://dx.doi.org/10.1186/1471-2199-10-96
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2009):
Porcine muscle sensory attributes associate with major changes in gene networks invoving CAPZB, ANKDR1, and CTBP2. Funct Integr Genomic 9 (4): 455-471
https://dx.doi.org/10.1007/s10142-009-0131-1
Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T. (2009):
Cloning and tissue-specific expression of a delta-COP homologue in a freshwater and a brackish water-adapted strain of rainbow trout (Oncorhynchus mykiss). Genes Genet Syst 84 (3): 239-243
https://dx.doi.org/10.1266/ggs.84.239
Rebl, A.; Köllner, B.; Anders, E.; Wimmers, K.; Goldammer, T. (2009):
Peptidylarginine deiminase gene is differentially expressed in freshwater and brackish water rainbow trout. Mol Biol Rep 37 (5): 2333-2339
https://dx.doi.org/10.1007/s11033-009-9738-5
Muràni, E.; Ponsuksili, S.; Srikanchai, T.; Maak, S.; Wimmers, K. (2009):
Expression of the porcine adrenergic receptor beta 2 gene in longissimus dorsi muscle is affected by cis-regulatory DNA variation. Anim Genet 40 (1): 80-89
https://dx.doi.org/10.1111/j.1365-2052.2008.01811.x
Wimmers, K.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2009):
QTL for traits related to humoral immune response estimated from data of a porcine F2 resource population. INT J IMMUNOGENET 36 (3): 141-151
https://dx.doi.org/10.1111/j.1744-313X.2009.00838.x
Rehfeldt, C.; Mau, M.; Wimmers, K. (2009):
Chapter7. Regulatory aspects of fetal growth and muscle development relating to postnatal growth and carcass quality in pigs. In: Managing Prenatal Development to Enhance Livestock Productivity (Paul L. Greenwood, Alan W. Bell, Philip E. Vercoe, Gerrit J. Viljoen, Hrsg.) Springer, The Netherlands, IAEA, (978-90-481-3134-1): 203-241
Maak, S.; Boettcher, D.; Tetens, J.; Swalve, H. H.; Wimmers, K.; Thaller, G. (2009):
Expression of microRNAs is not related to increased expression of ZDHHC9 in hind leg muscles of splay leg piglets. Mol Cell Probe 24 (1): 32-37
https://dx.doi.org/10.1016/j.mcp.2009.09.001
Metges, C. C.; Peters, M.; Sauerwein, H.; Ooster, A.; Ponsuksili, S.; Altmann, S.; Oster, M.; Rehfeldt, C.; Wimmers, K. (2009):
Fetal Programming: Mütterliche Ernährung und Merkmalsausprägung der Nachkommen beim Schwein. Genomexpress (1.09): 11-13
Tetzlaff, S.; Muràni, E.; Schellander, K.; Ponsuksili, S.; Wimmers, K. (2009):
Differential expression of growth factors and their receptors points out their involvement in the inverted teat defect in pigs. J Anim Sci 87 (11): 3451-3457
https://dx.doi.org/10.2527/jas.2008-1660
Tetzlaff, S.; Jonas, E; Phatsara, C.; Muràni, E.; Ponsuksili, S.; Schellander, K.; Wimmers, K. (2009):
Evidence for association of lymphoid enhancer-binding factor-1 (LEF1) with the number of functional and inverted teats in pigs. Cytogenet Genome Res 124 (2): 139-146
https://dx.doi.org/10.1159/000207521
Tetzlaff, S.; Chomdej, S.; Jonas, E; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schellander, K.; Wimmers, K. (2009):
Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs. J Anim Breed Genet 126 (3): 237-241
https://dx.doi.org/10.1111/j.1439-0388.2008.00781.x
Maak, S.; Boettcher, D.; Tetens, J.; Wensch-Dorendorf, M.; Nürnberg, G.; Wimmers, K.; Swalve, H. H.; Thaller, G. (2009):
Identification of candidate genes for congenital splay leg in piglets by alternative analysis of DNA microarray data. Int J Biol Sci 5 (4): 331-337
https://dx.doi.org/10.7150/ijbs.5.331
Ponsuksili, S.; Muràni, E.; Phatsara, C.; Jonas, E; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K. (2008):
Expression profiling of muscle reveals transcripts differentially expressed in muscle that affect water-holding capacity of pork. J Agr Food Chem 56 (21): 10311-10317
https://dx.doi.org/10.1021/jf800881y
Wimmers, K.; Ngu, N.T.; Jennen, D.; Tesfaye, D.; Muràni, E.; Schellander, K.; Ponsuksili, S. (2008):
Relationship between myosin heavy chain isoform expression and muscling in several diverse pig breeds. J Anim Sci 86 (4): 795-803
https://dx.doi.org/10.2527/jas.2006-521