Prof. Dr. rer. nat. Klaus Wimmers
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Leibniz-Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Leibniz-Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Muràni, E.; Reyer, H.; Ponsuksili, S.; Fritschka, S.; Wimmers, K. (2012):
A substitution in the ligand binding domain of the porcine glucocorticoid receptor affects activity of the adrenal gland. Plos One 7 (9): 1-10
https://dx.doi.org/10.1371/journal.pone.0045518
Brunner, R. M.; Srikanchai, T.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2012):
Genes with expression levels correlating to drip loss prove association of their polymorphism with water holding capacity of pork. Mol Biol Rep 39 (1): 97-107
https://dx.doi.org/10.1007/s11033-011-0714-5
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs. J Anim Sci 90 (1): 1-15
https://dx.doi.org/10.2527/jas.2011-4269
Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Anders, E.; Wimmers, K.; Goldammer, T. (2012):
Comparative molecular characterization of the regucalcin (RGN) gene in rainbow trout (Oncorhynchus mykiss) and maraena whitefish (Coregonus marena). Mol Biol Rep 39 (4): 4291-4300
https://dx.doi.org/10.1007/s11033-011-1216-1
Rebl, A.; Verleih, M.; Korytar, T.; Kühn, C.; Wimmers, K.; Köllner, B.; Goldammer, T. (2012):
Identification of differentially expressed protective genes in liver of two rainbow trout strains. VET IMMUNOL IMMUNOP 145 (1-2): 305-315
https://dx.doi.org/10.1016/j.vetimm.2011.11.023
Wimmers, K.; Do, V. A. K.; Schütze, S.; Muràni, E.; Ponsuksili, S. (2011):
The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes. BMC Proceedings 5 (Suppl.4): S19, 1-4
https://dx.doi.org/10.1186/1753-6561-5-S4-S19
Laenoi, W.; Uddin, M. J.; Cinar, M. U.; Grosse-Brinkhaus, C.; Tesfaye, D.; Jonas, E; Scholz, A. M.; Tholen, E.; Looft, C.; Wimmers, K.; Phatsara, C.; Jüngst, H.; Sauerwein, H.; Mielenz, M.; Schellander, K. (2011):
Quantitative trait loci analysis for leg weakness-related traits in a Duroc x Pietrain crossbred population. Genet Sel Evol 43: 13-20
https://dx.doi.org/10.1186/1297-9686-43-13
Do, V. A. K.; Ponsuksili, S.; Muràni, E.; Wimmers, K. (2011):
Polymorphic sites in the 5'-region of the porcine C8A gene. Arch Tierzucht 54 (4): 430-438
Uddin, M. J.; Cinar, M. U.; Grosse-Brinkhaus, C.; Tesfaye, D.; Tholen, E.; Jüngst, H.; Looft, C.; Wimmers, K.; Phatsara, C.; Schellander, K. (2011):
Mapping quantitative trait loci for innate immune response in the pig. INT J IMMUNOGENET 38 (2): 121-131
https://dx.doi.org/10.1111/j.1744-313X.2010.00985.x
Ponsuksili, S.; Muràni, E.; Brand, B.; Schwerin, M.; Wimmers, K. (2011):
Integrating expression profiling and whole-genome association for dissection of fat traits in a porcine model. J Lipid Res 52 (4): 668-678
https://dx.doi.org/10.1194/Jlr.M013342
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2011):
A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model. Plos One 6 (7): 1-12
https://dx.doi.org/10.1371/journal.pone.0021691
Gandolfi, G.; Cinar, M. U.; Ponsuksili, S.; Wimmers, K.; Tesfaye, D.; Looft, C.; Jüngst, H.; Tholen, E.; Phatsara, C.; Schellander, K.; Davoli, R. (2011):
Association of PPARGC1A and CAPNS1 gene polymorphisms and expression with meat quality traits in pigs. Meat Sci 89 (4): 478-485
https://dx.doi.org/10.1016/j.meatsci.2011.05.015
Kayan, A.; Cinar, M. U.; Uddin, M. J.; Phatsara, C.; Wimmers, K.; Ponsuksili, S.; Tesfaye, D.; Looft, C.; Jüngst, H.; Tholen, E.; Schellander, K. (2011):
Polymorphism and expression of the porcine Tenascin C gene associated with meat and carcass quality. Meat Sci 89 (1): 76-83
https://dx.doi.org/10.1016/j.meatsci.2011.04.001
Kayan, A.; Uddin, M. J.; Cinar, M. U.; Grosse-Brinkhaus, C.; Phatsara, C.; Wimmers, K.; Ponsuksili, S.; Tesfaye, D.; Looft, C.; Jüngst, H.; Tholen, E.; Schellander, K. (2011):
Investigation on interferon alpha-inducible protein 6 (IFI6) gene as a candidate for meat and carcass quality in pig. Meat Sci 89 (4): 755-760
https://dx.doi.org/10.1016/j.meatsci.2011.03.009
Muràni, E.; Ponsuksili, S.; D´Eath, R. B.; Turner, S.P.; Evans, G.; Thölking, L.; Kurt, E.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2011):
Differential mRNA expression of genes in the porcine adrenal gland associated with psychosocial stress. J Mol Endocrinol 46 (3): 165-174
https://dx.doi.org/10.1530/Jme-10-0147
Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kühn, C.; Wimmers, K.; Goldammer, T. (2011):
Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses. In: Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses (Schwerin M. Editoren Heft 18: Seyfert, H-M, Viereck G, Hrsg.) BUK!, Kiel (0946-1981) (18): 39-41
Rebl, A.; Köbis, J.; Fischer, K.; Takizawa, F.; Verleih, M.; Wimmers, K.; Goldammer, T. (2011):
MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after VHSV infection.. Fish Shellfish Immun 31 (6): 1041-1050
https://dx.doi.org/10.1016/j.fsi.2011.09.004
Rehfeldt, C.; te Pas, M. F. W.; Wimmers, K.; Brameld, J. M.; Nissen, P. M.; Berri, C.; Valente, L. M. P.; Power, D. M.; Picard, B.; Stickland, N. C.; Oksbjerg, N. (2011):
Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II. Genetic factors related to animal performance and advances in methodology. Animal 5 (5): 718-730
https://dx.doi.org/10.1017/S1751731110002454
Rehfeldt, C.; te Pas, M. F. W.; Wimmers, K.; Brameld, J. M.; Nissen, P. M.; Berri, C.; Valente, L. M. P.; Power, D. M.; Picard, B.; Stickland, N. C.; Oksbjerg, N. (2011):
Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I. Regulation of myogenesis and environmental impact. Animal 5 (5): 703-717
https://dx.doi.org/10.1017/S1751731110002089
Laenoi, W.; Uddin, M. J.; Cinar, U; Grosse-Brinkhaus, C; Tesfaye, D.; Jonas, E; Scholz, A. M.; Tholen, E.; Looft, C.; Wimmers, K.; Phatsara, C.; Sauerwein, H.; Schellander, K. (2010):
QTL mapping for leg weakness related traits in a Duroc x Pietrain F2 resource population. In: Proceedings of the 9th World Congress on Genetics Applied to Livestock Production (Gesellschaft für Tierzuchtwissenschaften e.V., Hrsg.) (978-3-00-031608-1) (2010): 724