Prof. Dr. rer. nat. habil. Klaus Wimmers
Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Nossol, C.; Barta-Böszörményi, A.; Kahlert, S.; Zuschratter, W.; Faber-Zuschratter, H.; Reinhardt, N.; Ponsuksili, S.; Wimmers, K.; Diesing, A.-K.; Rothkötter, H.-J. (2015):
Comparing two intestinal porcine epithelial cell lines (IPECs): morphological differentiation, function and metabolism. Plos One 10 (7): e0132323, 1-20
https://dx.doi.org/10.1371/journal.pone.0132323
Kluess, J. W.; Kahlert, S.; Kröber, A.; Diesing, A.-K.; Rothkötter, H.-J.; Wimmers, K.; Dänicke, S. (2015):
Deoxynivalenol, but not E. coli lipopolysaccharide, changes the response pattern of intestinal porcine epithelial cells (IPEC-J2) according to its route of application. Toxicol lett 239 (3): 161-171
https://dx.doi.org/10.1016/j.toxlet.2015.09.019
Schering, L.; Hoene, M.; Kanzleiter, T.; Jähnert, M.; Wimmers, K.; Klaus, S.; Eckel, J.; Weigert, C.; Schürmann, A.; Maak, S.; Jonas, W.; Sell, H. (2015):
Identification of novel putative adipomyokines by a cross-species annotation of secretomes and expression profiles. Arch Physiol Biochem 121 (5): 194-205
https://dx.doi.org/10.3109/13813455.2015.1092044
Wu, Z.; Gaur, U.; Mekchay, S.; Peng, X.; Li, L.; Sun, H.; Song, Z.; Dong, B.; Li, M.; Wimmers, K.; Ponsuksili, S.; Li, S.; Mei, S.; Liu, G. (2015):
Genome-wide identification of allele-specific expression in response to Streptococcus suis 2 infection in two differentially susceptible pig breeds. J Appl Genet 56 (4): 481-491
https://dx.doi.org/10.1007/s13353-015-0275-8
Siengdee, P.; Trakooljul, N.; Muràni, E.; Brand, B.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
Pre- and post-natal muscle microRNA expression profiles of two pig breeds differing in muscularity. Gene 561 (2): 190-198
https://dx.doi.org/10.1016/j.gene.2015.02.035
Ponsuksili, S.; Siengdee, P.; Du, Y.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K. (2015):
Identification of common regulators of genes in co-expression networks affecting muscle and meat properties. Plos One 10 (4): e0123678, 1-18
https://dx.doi.org/10.1371/journal.pone.0123678
Siengdee, P.; Trakooljul, N.; Muràni, E.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
MicroRNAs regulate cellular ATP levels by targeting mitochondrial energy metabolism genes during C2C12 myoblast differentiation. Plos One 10 (5): e0127850, 1-20
https://dx.doi.org/10.1371/journal.pone.0127850
Adler, M.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2015):
PBMC transcriptomic responses to primary and secondary vaccination differ due to divergent lean growth and antibody titers in a pig model. Physiol Genomics 47 (10): 470-478
https://dx.doi.org/10.1152/physiolgenomics.00015.2015
Liu, X; Du, Y.; Trakooljul, N.; Brand, B.; Muràni, E.; Krischek, C.; Wicke, M.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2015):
Muscle transcriptional profile based on muscle fiber, mitochondrial respiratory activity, and metabolic enzymes. Int J Biol Sci 11 (12): 1348-1362
https://dx.doi.org/10.7150/ijbs.13132
Ponsuksili, S.; Zebunke, M.; Muràni, E.; Trakooljul, N.; Krieter, J.; Puppe, B.; Schwerin, M.; Wimmers, K. (2015):
Integrated Genome-wide association and hypothalamus eQTL studies indicate a link between the circadian rhythm-related gene PER1 and coping behavior. Sci Rep-UK 5: 16264, 1-14
https://dx.doi.org/10.1038/srep16264
Schering, L.; Albrecht, E.; Liu, S.; Kühn, C.; Wimmers, K.; Maak, S. (2015):
Molekulare Ursachen einer differenten Expression von THRSP im bovinen Skelettmuskel. In: 16th Day of the Doctoral Student : abstracts, 13 May 2014 Dummerstorf (Schriftenreihe / Leibniz-Institut für Nutztierbiologie , 24) (Christa Kühn, Gunther Viereck, Hrsg.): 17-20
Kunze, M.; Wirthgen, E.; Walz, C.; Spitschak, M.; Brenmoehl, J.; Vanselow, J.; Schwerin, M.; Wimmers, K.; Hoeflich, A. (2015):
Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC-MS/MS. J Chromatogr B 1007: 132-139
https://dx.doi.org/10.1016/j.jchromb.2015.10.010
Reyer, H.; Hawken, R.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2015):
The genetics of feed conversion efficiency traits in a commercial broiler line. Sci Rep-UK 5: 16387, 1-11
https://dx.doi.org/10.1038/srep16387
Jaeger, A.; Fritschka, S.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Identification and functional characterization of cis-regulatory elements controlling expression of the porcine ADRB2 gene. Int J Biol Sci 11 (9): 1006-1015
https://dx.doi.org/10.7150/ijbs.12456
Jaeger, A.; Bardehle, D.; Oster, M.; Günther, J.; Muràni, E.; Ponsuksili, S.; Wimmers, K.; Kemper, N. (2015):
Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro. Vet Res 46: 50, 1-18
https://dx.doi.org/10.1186/s13567-015-0178-z
Oster, M.; Scheel, M.; Muràni, E.; Ponsuksili, S.; Zebunke, M.; Puppe, B.; Wimmers, K. (2015):
The fight-or-flight response is associated with PBMC expression profiles related to immune defence and recovery in swine. Plos One 10 (3): e0120153, 1-15
https://dx.doi.org/10.1371/journal.pone.0120153
Görres, A.; Ponsuksili, S.; Wimmers, K.; Muràni, E. (2015):
Analysis of non-synonymous SNPs of the porcine SERPINA6 gene as potential causal variants for a QTL affecting plasma cortisol levels on SSC7. Anim Genet 46 (3): 239-246
https://dx.doi.org/10.1111/age.12276
Muràni, E.; Reyer, H.; Görres, A.; Tuchscherer, A.; Kanitz, E.; Ponsuksili, S.; Wimmers, K. (2014):
From phenotype to QTN and back: Identification and characterization of a genetic variant of the porcine glucocorticoid receptor with a major effect on HPA axis activity. In: Proceedings / 10th World Congress of Genetics Applied to Livestock Production (https://asas.org/wcgalp-proceedings) (https://asas.org/wcgalp-proceedings/species-breeding-swine): 371
Do, V. A. K.; Wimmers, K. (2014):
Assignment for genes encoding the terminal complement components to porcine chromosome. Biotechnology in Animal Husbandry 30 (3): 407-414
https://dx.doi.org/10.2298/BAH1403407A
Oster, M.; Muràni, E.; Ponsuksili, S.; D´Eath, R. B.; Turner, S.P.; Evans, G.; Thölking, L.; Kurt, E.; Klont, R.; Foury, A.; Mormède, P.; Wimmers, K. (2014):
Transcriptional responses of PBMC in psychosocially stressed animals indicate an alerting of the immune system in female but not in castrated male pigs. BMC Genomics 15: 967-978
https://dx.doi.org/10.1186/1471-2164-15-967