Prof. Dr. rer. nat. habil. Klaus Wimmers

Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

Research interests

  • inheritance and expression of traits related to productive adaptability and resilience in livestock
  • Trait-associated variation at the molecular levels of the genotype-phenotype map
  • Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

  • since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
  • 2008-2016: adjunct Professor, University of Bonn
  • 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
  • 2002: habilitation in Animal Breeding and Genetics, University of Bonn
    1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
  • 1994: doctorate (Dr. rer. nat.)
  • 1990-1996: research fellow at the Institute of Animal production, TU Berlin
  • 1989: Study of veterinary science, FU Berlin

Teaching

  • Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Ponsuksili, S.; Siengdee, P.; Li, S.; Kriangwanich, W.; Oster, M.; Reyer, H.; Wimmers, K. (2024):
Effect of metabolically divergent pig breeds and tissues on mesenchymal stem cell expression patterns during adipogenesis
BMC Genomics 25: 407, 1-15
https://doi.org/10.1186/s12864-024-10308-z
Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2024):
Dynamics of DNA methylation during osteogenic differentiation of porcinesynovial membrane mesenchymal stem cells from two metabolically distinctbreeds
Epigenetics 19 (1): 2375011, 1-15
https://doi.org/10.1080/15592294.2024.2375011
Koch, F.; Reyer, H.; Görs, S.; Hansen, C.; Wimmers, K; Kuhla, B. (2024):
Heat stress and feeding effects on the mucosa-associated and digesta microbiome and their relationship to plasma and digesta fluid metabolites in the jejunum of dairy cows
Journal of Dairy Science 107: 5162-5177
https://doi.org/10.3168/jds.2023-24242
Hasan, M.; Reyer, H.; Oster, M.; Trakooljul, N.; Ponsuksili, S.; Magowan, E.; Fischer, D.-C.; Wimmers, K. (2024):
Exposure to artificial ultraviolet-B light mediates alterations on the hepatic transcriptome and vitamin D metabolism in pigs
J Steroid Biochem Mol Biol 236: 106428, 1-8
https://doi.org/10.1016/j.jsbmb.2023.106428
Reyer, H.; Abou-Soliman, I.; Schulze, M.; Henne, H.; Reinsch, N.; Schön, J.; Wimmers, K. (2024):
Genome-Wide Association Analysis of Semen Characteristics in Piétrain Boars.
Genes 15 (3): 382, 1-12
https://doi.org/10.3390/genes15030382
Nossol, C.; Landgraf, P.; Oster, M.; Kahlert, S.; Barta-Böszörmenyi, A.; Kluess, J.; Wimmers, K.; Isermann, B.; Stork, O.; Dieterich, D. C.; Dänicke, S.; Rothkötter, H. J. (2024):
Deoxynivalenol triggers the expression of IL-8-related signaling cascades and decreases protein biosynthesis in primary monocyte-derived cells
Mycotoxin research 40 (2): 279-293
https://doi.org/10.1007/s12550-024-00528-3
Koch, F.; Reyer, H.; Görs, S.; Hansen, C.; Wimmers, K.; Kuhla, B. (2024):
Heat stress and feeding effects on the mucosa-associated and digesta microbiome and their relationship to plasma and digesta fluid metabolites in the jejunum of dairy cows [epublished ahead of print].
Journal of dairy science
https://doi.org/10.3168/jds.2023-24242
Omotoso, A. O.; Reyer, H.; Oster, M.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2023):
Broiler physiological response to low phosphorus diets at different stages of production. Poultry Sci 102 (2): 102351, 1-38
Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2023):
The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains. Poultry Sci 102 (1): 102256, 1-14
Sallam, A. M.; Reyer, H.; Wimmers, K.; Bertolini, F.; Aboul-Naga, A.; Braz, C. U.; Rabee, A. E. (2023):
Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds
BMC Genomics 24: 573, 1-16
https://doi.org/10.1186/s12864-023-09679-6
Sallam, A. M.; Abousoliman, I.; Reyer, H.; Wimmers, K.; Rabee, A. E. (2023):
New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats
Sci Rep 13: 20086, 1-17
https://doi.org/10.1038/s41598-023-46997-x
Li, S.; Siengdee, P.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2023):
Transcriptome changes during osteogenesis of porcine mesenchymal stem cells derived from different types of synovial membranes and genetic background
Sci Rep 13: 10048, 1-15
https://doi.org/10.1038/s41598-023-37260-4
Dotsev, A. V.; Koshkina, O.; Kharzinova, V. R.; Deniskova, T. E.; Reyer, H.; Kunz, E.; Mészáros, G.; Shakhin, A.; Petrov, S. N.; Medvedev, D.; Kuksin, A.; Bat-Erdene, G.; Munkhtsog, B.; Bagirov, V. A.; Wimmers, K.; Sölkner, J.; Medugorac, I.; Zinovieva, N. A. (2023):
Genome-wide insights into intraspecific taxonomy and genetic diversity of argali (Ovis ammon).
Diversity 15 (5): 627, 1-13
https://doi.org/10.3390/d15050627
Prahl, M. C.; Müller, C. B. M.; Wimmers, K.; Kuhla, B. (2023):
Mammary gland, kidney and rumen urea and uric acid transporters of dairy cows differing in milk urea concentration. Sci Rep-UK 13: 17231, 1-12
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Wimmers, K. (2023):
Jejunal Microbiota of Broilers fed varying Levels of Mineral Phosphorus [epublished ahead of print]. Poultry Sci
Brenmoehl, J.; Brosig, E.; Trakooljul, N.; Walz, C.; Ohde, D.; Noce, A.; Walz, M.; Langhammer, M.; Petkov, S.; Röntgen, M.; Maak, S.; Galuska, C. E.; Fuchs, B.; Kuhla, B.; Ponsuksili, S.; Wimmers, K.; Hoeflich, A. (2023):
Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC) - a Possible Role of Lactate Dehydrogenase in Metabolic Flexibility. Cells-Basel 12 (15): 1925, 1-21
Gu, H.; Du, Z.; Murani, E.; D Alessandro, E.; Chen, C,; Wang, X.; Mao, J.; Wimmers, K.; Song, C. (2023):
A 314-bp SINE insertion in the ZNF2 promoter region may act as a repressor related to regulation of fat deposition in pigs. J Integr Agr 22 (2): 526-536
Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2023):
RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken. Evol Appl 16 (6): 1135-1153
Honerlagen, H.; Reyer, H.; Abousoliman, I.; Segelke, D.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2023):
Microbial signature inferred from genomic breeding selection on milk urea concentration and its relation to proxies of nitrogen-utilization efficiency in Holsteins. J Dairy Sci 106 (7): 4682-4697
Pan, Z.; Wang, Y.; Wang, M.; Wang, Y.; ZHU, X.; Gu, H.; Zhong, C.; An, L.; Shan, M.; Damas, J.; Halstead, M.; Guan, D.; Trakooljul, N.; Wimmers, K.; Bi, Y.; Wu, S.; Delany, M. E.; Bai, X; Cheng, H.; Sun, C.; Yang, N.; Hu, X.; Lewin, H.A.; Fang, L.; Zhou, H. (2023):
An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics. SCI ADV 9 (18): 1-14