Prof. Dr. rer. nat. habil. Klaus Wimmers
Research interests
- inheritance and expression of traits related to productive adaptability and resilience in livestock
- Trait-associated variation at the molecular levels of the genotype-phenotype map
- Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction
Curriculum Vitae
- since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
- 2008-2016: adjunct Professor, University of Bonn
- 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
- 2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn - 1994: doctorate (Dr. rer. nat.)
- 1990-1996: research fellow at the Institute of Animal production, TU Berlin
- 1989: Study of veterinary science, FU Berlin
Teaching
- Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock
Publications
Paul, D.; Oster, M.; Ponsuksili, S.; Wimmers, K.; Reyer, H. (2025):
Genome-wide association study of blood vitamin D metabolites and bone remodelling markers in pigs
BMC Genomics 26: 718
https://doi.org/10.1186/s12864-025-11914-1
Oster, M.; Qasir, H.; Reyer, H.; Ponsuksili, P.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
Transcriptional and endocrine orchestration of medullary bone formation and mineral turn-over in female chickens
Poultry Science 104 (11): 105798
https://doi.org/10.1016/j.psj.2025.105798
Meier, L.; Wallauch, N.; Feger, M.; Oster, M.; Sommerfeld, V.; Schmucker, S.; Wimmers, K.; Huber, K.; Stefanski, V.; Rodehutscord, M.; Föller, M. (2025):
Expression of fibroblast growth factor 23 (FGF23) and αKlotho in two commercial laying hen strains fed with and without dietary mineral P supplements before and after the onset of the laying phase
Poultry Science 104 (11): 105639
https://doi.org/10.1016/j.psj.2025.105639
Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Wimmers, K.; Ponsuksili, S. (2025):
A comprehensive analysis of allele-specific expression and transcriptomic profiling in pig limbic and endocrine tissues
Frontiers in Molecular Neuroscience 18: 1616363
https://doi.org/10.3389/fnmol.2025.1616363
Oster, M.; Reyer, H.; Hadlich, F.; Ponsuksili, S.; Wolf, P.; Wimmers, K.; Keiler, J. (2025):
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs
Animal Nutrition
https://doi.org/10.1016/j.aninu.2025.04.007
Qasir, H.; Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Muráni, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
Effects of a transient lack of dietary mineral phosphorus on renal gene expression and plasma metabolites in two high-yielding laying hen strains
BMC Genomics 26: 129, 1-13
https://doi.org/10.1186/s12864-025-11294-6
Ponsuksili, S.; Muráni, E.; Fuchs, B.; Galuska, C. E.; Reyer, H.; Iqbal, M. A.; Li, S.; Oster, M.; Wimmers, K. (2025):
Genetic regulation and variation of fetal plasma metabolome in the context of sex, paternal breeds and variable fetal weight
Open Biology 15 (3): 240285, 1-20
https://doi.org/10.1098/rsob.240285
Ponsuksili, S.; Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2025):
DNA methylation in adipocyte differentiation of porcine mesenchymal stem cells and the impact of the donor metabolic type
Genomics
https://doi.org/10.1016/j.ygeno.2025.111050
Oster, M.; Gladbach, C. A.; Vernunft, A.; Reyer, H.; Otten, W.; Metges, C. C.; Muráni, E.; Ponsuksili, S.; Frölich, K.; Wimmers, K.; Bostedt, H. (2025):
Influence of genotype-environment interaction on stress parameters during spontaneous farrowing in modern and traditional pig breeds housed in crates and pens
Theriogenology 240: 117394, 1-11
https://doi.org/10.1016/j.theriogenology.2025.117394
Lickfett, H.; Oster, M.; Vernunft, A.; Reyer, H.; Görs, S.; Metges, C. C.; Bostedt, H.; Wimmers, K. (2025):
Influence of genotype and environment on piglet vitality and metabolic state during the suckling period of divergent birth weight classes
Animal 19 (4): 101460, 1-14
https://doi.org/10.1016/j.animal.2025.101460
Cavalleri, M.; Sciascia, Q. L.; Görs, S.; Vernunft, A.; Reyer, H.; Wimmers, K.; Zentek, J.; Kluess, J.; Dänicke, S.; Metges, C. C. (2025):
Measurement of Oro-Cecal Transit Time in LPS-Treated Pigs Fed High and Low Fiber Diets Using the Lactose-13C-Ureide Test in Breath and Saliva Samples
Journal of Agricultural and Food Chemistry
https://doi.org/10.1021/acs.jafc.5c00534
Reyer, H.; Mielenz, M.; Daş, G.; Metges, C. C.; Wimmers, K. (2025):
Microbial profiling of black soldier fly larvae reared on substrates supplemented with different mineral sources originating from phosphorus recycling technologies
Animal Microbiome 7: 14, 1-14
https://doi.org/10.1186/s42523-025-00380-5
Ponsuksili, S.; Hadlich, F.; Li, S.; Trakooljul, N.; Reyer, H.; Oster, M.; Abitew, Y. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages
Physiological Genomics 57 (3): 125-139
https://doi.org/10.1152/physiolgenomics.00063.2024
Muráni, E.; Trakooljul, N.; Hadlich, F.; Wimmers, K. (2025):
Transcriptional signature of a hypersensitive glucocorticoid receptor variant in the neuroendocrine system suggests enhanced vulnerability to brain disorders
Brain, Behavior and Immunity 124 (2): 335-346
https://doi.org/10.1016/j.bbi.2024.12.004
Ma, W.; Brenmoehl, J.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2025):
Dexamethasone has profound influence on the energy metabolism of porcine blood leukocytes and prevents the LPS-induced glycolytic switch
Frontiers in Immunology 16: 1514061, 1-13
https://doi.org/10.3389/fimmu.2025.1514061
Sommerfeld, V.; Hanauska, A.; Huber, K.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):
Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens
Poultry Science: 104545, 1-30
https://doi.org/10.1016/j.psj.2024.104545
Sommerfeld, V.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Huber, H.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):
Effects of feeding diets without mineral P supplement on intestinal phytate degradation, blood concentrations of Ca and P, and excretion of Ca and P in two laying hen strains before and after onset of laying activity
Poultry Science 103 (12): 104407, 1-12
https://doi.org/10.1016/j.psj.2024.104407
Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Metzler-Zebeli, B.; Wimmers, K. (2024):
Hepatic Transcriptomics of Broilers with Low and High Feed Conversion in Response to Caloric Restriction
Metabolites 14: 625, 1-13
https://doi.org/10.3390/metabo14110625
Honerlagen, H.; Reyer, H.; Wimmers, K. (2024):
Fundamental insights into the host genome - rumen microbiota - trait complex of cow-individual nitrogen (N) utilisation and N excretion
Züchtungskunde 96 (1), 34-42
Abitew, Y. A.; Reyer, H.; Hadlich, F.; Oster, M.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2024):
Transcriptional responses to diets without mineral phosphorus supplementation in the jejunum of two high-yielding laying hen strains
Poultry Science 103 (12): 104484, 1-11
https://doi.org/10.1016/j.psj.2024.104484