Prof. Dr. rer. nat. habil. Klaus Wimmers

Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

ResearchGate

Research interests

inheritance and expression of traits related to productive adaptability and resilience in livestock
Trait-associated variation at the molecular levels of the genotype-phenotype map
Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
2008-2016: adjunct Professor, University of Bonn
2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
1994: doctorate (Dr. rer. nat.)
1990-1996: research fellow at the Institute of Animal production, TU Berlin
1989: Study of veterinary science, FU Berlin

Teaching

Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Reyer, H.; Honerlagen, H.; Oster, M.; Ponsuksili, S.; Kuhla, B.; Wimmers, K. (2024):

Multi-tissue gene expression profiling of cows with a genetic predisposition for low and high milk urea levels

Henry Reyer, Michael Oster, Siriluck Wimmers, Björn Kuhla, Klaus Wimmers

Animal Biotechnology 35 (1): 2322542, 1-9

https://doi.org/10.1080/10495398.2024.2322542

Kalbfleisch, T. S.; McKay, S. D.; Murdoch, B. M.; Adelson, D. L.; Almansa-Villa, D.; Becker, G.; Beckett, L. M.; Benítez-Galeano, M. J.; Biase, F.; Casey, T.; Chuong, E.; Clark, E.; Clark, S.; Cockett, N.; Couldrey, C.; Davis, B. W.; Elsik, C. G.; Faraut, T.; Gao, Y.; Genet, C.; Grady, P.; Green, J.; Green, R.; Guan, D.; Hagen, D.; Hartley, G. A.; Heaton, M.; Hoyt, S. J.; Huang, W.; Jarvis, E.; Kalleberg, J.; Khatib, H.; Koepfi, K.-P.; Koltes, J.; Koren, S.; Kuehn, C.; Leeb, T.; Leonard, A.; Liu, G. E.; Low, W. Y.; McConnell, H.; McRae, K.; Miga, K.; Mousel, M.; Neibergs, H.; Olagunju, T.; Pennell, M.; Petry, B.; Pewsner, M.; Phillippy, A. M.; Pickett, B. D.; Pineda, P.; Potapova, T.; Rachagani, S.; Rhie, A.; Rijnkels, M.; Robic, A.; Osorio, N. R.; Safonova, Y.; Schettini, G.; Schnabel, R. D.; Natesh, N. S.; Stegemiller, N. R.; Storer, J.; Stothard, P.; Stull, C.; Tosser-Klopp, G.; Traglia, G. M.; Tuggle, C. K.; Tassell, C. P. Van; Watson, C.; Weikard, R.; Wimmers, K.; Xie, S.; Yang, L.; Smith, T. P. L.; O’Neil, R. J.; Rosen, B. D. (2024):

The Ruminant Telomere-to-Telomere (RT2T) Consortium

Klaus Wimmers

Nature genetics 56: 1566-1573

https://www.nature.com/articles/s41588-024-01835-2

Ponsuksili, S.; Siengdee, P.; Li, S.; Kriangwanich, W.; Oster, M.; Reyer, H.; Wimmers, K. (2024):

Effect of metabolically divergent pig breeds and tissues on mesenchymal stem cell expression patterns during adipogenesis

Siriluck Wimmers, Shuaichen Li, Michael Oster, Henry Reyer, Klaus Wimmers

BMC Genomics 25: 407, 1-15

https://doi.org/10.1186/s12864-024-10308-z

Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2024):

Dynamics of DNA methylation during osteogenic differentiation of porcinesynovial membrane mesenchymal stem cells from two metabolically distinctbreeds

Shuaichen Li, Michael Oster, Henry Reyer, Klaus Wimmers, Siriluck Wimmers

Epigenetics 19 (1): 2375011, 1-15

https://doi.org/10.1080/15592294.2024.2375011

Koch, F.; Reyer, H.; Görs, S.; Hansen, C.; Wimmers, K; Kuhla, B. (2024):

Heat stress and feeding effects on the mucosa-associated and digesta microbiome and their relationship to plasma and digesta fluid metabolites in the jejunum of dairy cows

Franziska Koch, Henry Reyer, Solvig Görs, Klaus Wimmers, Björn Kuhla

Journal of Dairy Science 107: 5162-5177

https://doi.org/10.3168/jds.2023-24242

Hasan, M.; Reyer, H.; Oster, M.; Trakooljul, N.; Ponsuksili, S.; Magowan, E.; Fischer, D.-C.; Wimmers, K. (2024):

Exposure to artificial ultraviolet-B light mediates alterations on the hepatic transcriptome and vitamin D metabolism in pigs

Henry Reyer, Michael Oster, Siriluck Wimmers, Klaus Wimmers

J Steroid Biochem Mol Biol 236: 106428, 1-8

https://doi.org/10.1016/j.jsbmb.2023.106428

Reyer, H.; Abou-Soliman, I.; Schulze, M.; Henne, H.; Reinsch, N.; Schön, J.; Wimmers, K. (2024):

Genome-Wide Association Analysis of Semen Characteristics in Piétrain Boars

Henry Reyer, Norbert Reinsch, Klaus Wimmers

Genes 15 (3): 382, 1-12

https://doi.org/10.3390/genes15030382

Nossol, C.; Landgraf, P.; Oster, M.; Kahlert, S.; Barta-Böszörmenyi, A.; Kluess, J.; Wimmers, K.; Isermann, B.; Stork, O.; Dieterich, D. C.; Dänicke, S.; Rothkötter, H. J. (2024):

Deoxynivalenol triggers the expression of IL-8-related signaling cascades and decreases protein biosynthesis in primary monocyte-derived cells

Michael Oster, Klaus Wimmers

Mycotoxin research 40 (2): 279-293

https://doi.org/10.1007/s12550-024-00528-3

Omotoso, A. O.; Reyer, H.; Oster, M.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2023):

Broiler physiological response to low phosphorus diets at different stages of production. Poultry Sci 102 (2): 102351, 1-38

Henry Reyer, Michael Oster, Steffen Maak, Siriluck Wimmers, Klaus Wimmers

Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2023):

The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains. Poultry Sci 102 (1): 102256, 1-14

Siriluck Wimmers, Henry Reyer, Michael Oster, Muhammad Arsalan Iqbal, Klaus Wimmers

Sallam, A. M.; Reyer, H.; Wimmers, K.; Bertolini, F.; Aboul-Naga, A.; Braz, C. U.; Rabee, A. E. (2023):

Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds

Henry Reyer, Klaus Wimmers

BMC Genomics 24: 573, 1-16

https://doi.org/10.1186/s12864-023-09679-6

Sallam, A. M.; Abousoliman, I.; Reyer, H.; Wimmers, K.; Rabee, A. E. (2023):

New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats

Henry Reyer, Klaus Wimmers

Sci Rep 13: 20086, 1-17

https://doi.org/10.1038/s41598-023-46997-x

Li, S.; Siengdee, P.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2023):

Transcriptome changes during osteogenesis of porcine mesenchymal stem cells derived from different types of synovial membranes and genetic background

Michael Oster, Henry Reyer, Klaus Wimmers, Siriluck Wimmers

Sci Rep 13: 10048, 1-15

https://doi.org/10.1038/s41598-023-37260-4

Dotsev, A. V.; Koshkina, O.; Kharzinova, V. R.; Deniskova, T. E.; Reyer, H.; Kunz, E.; Mészáros, G.; Shakhin, A.; Petrov, S. N.; Medvedev, D.; Kuksin, A.; Bat-Erdene, G.; Munkhtsog, B.; Bagirov, V. A.; Wimmers, K.; Sölkner, J.; Medugorac, I.; Zinovieva, N. A. (2023):

Genome-wide insights into intraspecific taxonomy and genetic diversity of argali (Ovis ammon)

Henry Reyer, Klaus Wimmers

Diversity 15 (5): 627, 1-13

https://doi.org/10.3390/d15050627

Prahl, M. C.; Müller, C. B. M.; Wimmers, K.; Kuhla, B. (2023):

Mammary gland, kidney and rumen urea and uric acid transporters of dairy cows differing in milk urea concentration. Sci Rep-UK 13: 17231, 1-12

Klaus Wimmers, Björn Kuhla

Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Wimmers, K. (2023):

Jejunal Microbiota of Broilers fed varying Levels of Mineral Phosphorus

Michael Oster, Henry Reyer, Klaus Wimmers, Siriluck Wimmers

Poultry Sci

Brenmoehl, J.; Brosig, E.; Trakooljul, N.; Walz, C.; Ohde, D.; Noce, A.; Walz, M.; Langhammer, M.; Petkov, S.; Röntgen, M.; Maak, S.; Galuska, C. E.; Fuchs, B.; Kuhla, B.; Ponsuksili, S.; Wimmers, K.; Hoeflich, A. (2023):

Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC) - a Possible Role of Lactate Dehydrogenase in Metabolic Flexibility. Cells-Basel 12 (15): 1925, 1-21

Julia Brenmoehl, Klaus Wimmers, Siriluck Wimmers, Björn Kuhla, Beate Fuchs, Christina Galuska, Steffen Maak, Monika Röntgen, Andreas Höflich

Gu, H.; Du, Z.; Murani, E.; D Alessandro, E.; Chen, C,; Wang, X.; Mao, J.; Wimmers, K.; Song, C. (2023):

A 314-bp SINE insertion in the ZNF2 promoter region may act as a repressor related to regulation of fat deposition in pigs. J Integr Agr 22 (2): 526-536

Eduard Muráni, Klaus Wimmers

Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2023):

RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken. Evol Appl 16 (6): 1135-1153

Muhammad Arsalan Iqbal, Henry Reyer, Michael Oster, Eduard Muráni, Klaus Wimmers, Siriluck Wimmers

Honerlagen, H.; Reyer, H.; Abousoliman, I.; Segelke, D.; Ponsuksili, S.; Trakooljul, N.; Reinsch, N.; Kuhla, B.; Wimmers, K. (2023):

Microbial signature inferred from genomic breeding selection on milk urea concentration and its relation to proxies of nitrogen-utilization efficiency in Holsteins. J Dairy Sci 106 (7): 4682-4697

Henry Reyer, Siriluck Wimmers, Norbert Reinsch, Björn Kuhla, Klaus Wimmers