Prof. Dr. rer. nat. habil. Klaus Wimmers

Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

Research interests

  • inheritance and expression of traits related to productive adaptability and resilience in livestock
  • Trait-associated variation at the molecular levels of the genotype-phenotype map
  • Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

  • since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
  • 2008-2016: adjunct Professor, University of Bonn
  • 2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
  • 2002: habilitation in Animal Breeding and Genetics, University of Bonn
    1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
  • 1994: doctorate (Dr. rer. nat.)
  • 1990-1996: research fellow at the Institute of Animal production, TU Berlin
  • 1989: Study of veterinary science, FU Berlin

Teaching

  • Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Nalpadan, A. A.; Reyer, H.; Oster, M.; Trakooljul, N.; Ponsuksili, S.; Kozera, W.; Karpiesiuk, K.; Kepka-Borkowska, K.; Chalaskiewicz, K.; Pierzchala, M.; Taniguchi, H.; Lepczynski, A.; Slaska, B.; Asediya, V.; Pareek, C. S.; Wimmers, K. (2026):
Transcriptional insights into aflatoxin B1 induced hepatotoxicity and comparative effects of medicinal herbs in pigs
BMC Veterinary Research 22: 53, 1-11
https://doi.org/10.1186/s12917-025-05270-1
Richter, A.; Kinsky, L.; Lange, S.; Trakooljul, N.; Hadlich, F.; Sekora, A.; Knuebel, G.; Krohn, S.; Schmidt, C.; Busch, M.; Schreiber, T.; Kumstel, S.; Wimmers, K.; Murua Escobar, H.; Junghanss, C. (2025):
Venetoclax resistance in preclinical KMT2A-rearranged acute lymphoblastic leukemia models is characterized by high inter- and intra-model heterogeneity
npj Precision Oncology 10: 47, 1-12
https://doi.org/10.1038/s41698-025-01249-1
Reyer, H.; Oster, M.; Zentek, J.; Männer, K.; Trajoolkul, N.; Aumiller, T.; Wimmers, K. (2025):
Digestibility and transcriptomic profiling of kidney, pancreas, follicle, and uterus in laying hens supplemented with phytogenic feed additive
Poultry Science 105 (2): 106219, 1-7
https://doi.org/10.1016/j.psj.2025.106219
Ponsuksili, S.; Hadlich, F.; Trakooljul, N.; Li, S.; Reyer, H.; Oster, M.; Wimmers, K. (2025):
Tissue-Specific Chromatin Accessibility Regions and Transcription Factor Binding Sites in Pig Brain and Endocrine Tissues
Molecular Neurobiology 62: 13119-13135
https://doi.org/10.1007/s12035-025-05128-5
Oster, M.; Lickfett, H.; Vernunft, A.; Reyer, H.; Murani, E.; Bostedt, H.; Wimmers, K. (2025):
Neonatal blood count data of piglets in modern and traditional breeds following spontaneous or hormonally induced parturition
International Journal of Veterinary Science and Medicine
Ma, W.; Trakooljul, N.; Hadlich, F.; Wimmers, K.; Murani, E. (2025):
3D4 cells exhibit transcriptional features inconsistent with alveolar macrophage identity
Veterinary Research 56: 201, 1-11
https://doi.org/10.1186/s13567-025-01638-1
Lickfett, H.; Oster, M.; Vernunft, A.; Reyer, H.; Muráni, E.; Görs, S.; Metges, C. C.; Bostedt, H.; Wimmers, K. (2025):
Impact of parturition induction, farrowing environment and birth weight class on endocrine and metabolic plasma parameters related to piglet vitality
BMC Veterinary Research 21: 403, 1-15
https://doi.org/10.1186/s12917-025-04845-2
Paul, D.; Oster, M.; Ponsuksili, S.; Wimmers, K.; Reyer, H. (2025):
Genome-wide association study of blood vitamin D metabolites and bone remodelling markers in pigs
BMC Genomics 26: 718, 1-13
https://doi.org/10.1186/s12864-025-11914-1
Oster, M.; Qasir, H.; Reyer, H.; Ponsuksili, P.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
Transcriptional and endocrine orchestration of medullary bone formation and mineral turn-over in female chickens
Poultry Science 104 (11): 105798, 1-11
https://doi.org/10.1016/j.psj.2025.105798
Meier, L.; Wallauch, N.; Feger, M.; Oster, M.; Sommerfeld, V.; Schmucker, S.; Wimmers, K.; Huber, K.; Stefanski, V.; Rodehutscord, M.; Föller, M. (2025):
Expression of fibroblast growth factor 23 (FGF23) and αKlotho in two commercial laying hen strains fed with and without dietary mineral P supplements before and after the onset of the laying phase
Poultry Science 104 (11): 105639, 1-10
https://doi.org/10.1016/j.psj.2025.105639
Iqbal, M. A.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Wimmers, K.; Ponsuksili, S. (2025):
A comprehensive analysis of allele-specific expression and transcriptomic profiling in pig limbic and endocrine tissues
Frontiers in Molecular Neuroscience 18: 1616363, 1-22
https://doi.org/10.3389/fnmol.2025.1616363
Oster, M.; Reyer, H.; Hadlich, F.; Ponsuksili, S.; Wolf, P.; Wimmers, K.; Keiler, J. (2025):
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs
Animal Nutrition 22: 471-482
https://doi.org/10.1016/j.aninu.2025.04.007
Qasir, H.; Reyer, H.; Oster, M.; Ponsuksili, S.; Trakooljul, N.; Muráni, E.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
Effects of a transient lack of dietary mineral phosphorus on renal gene expression and plasma metabolites in two high-yielding laying hen strains
BMC Genomics 26: 129, 1-13
https://doi.org/10.1186/s12864-025-11294-6
Ponsuksili, S.; Muráni, E.; Fuchs, B.; Galuska, C. E.; Reyer, H.; Iqbal, M. A.; Li, S.; Oster, M.; Wimmers, K. (2025):
Genetic regulation and variation of fetal plasma metabolome in the context of sex, paternal breeds and variable fetal weight
Open Biology 15 (3): 240285, 1-20
https://doi.org/10.1098/rsob.240285
Ponsuksili, S.; Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2025):
DNA methylation in adipocyte differentiation of porcine mesenchymal stem cells and the impact of the donor metabolic type
Genomics 117 (3): 111050, 1-13
https://doi.org/10.1016/j.ygeno.2025.111050
Oster, M.; Gladbach, C. A.; Vernunft, A.; Reyer, H.; Otten, W.; Metges, C. C.; Muráni, E.; Ponsuksili, S.; Frölich, K.; Wimmers, K.; Bostedt, H. (2025):
Influence of genotype-environment interaction on stress parameters during spontaneous farrowing in modern and traditional pig breeds housed in crates and pens
Theriogenology 240: 117394, 1-11
https://doi.org/10.1016/j.theriogenology.2025.117394
Lickfett, H.; Oster, M.; Vernunft, A.; Reyer, H.; Görs, S.; Metges, C. C.; Bostedt, H.; Wimmers, K. (2025):
Influence of genotype and environment on piglet vitality and metabolic state during the suckling period of divergent birth weight classes
Animal 19 (4): 101460, 1-14
https://doi.org/10.1016/j.animal.2025.101460
Cavalleri, M.; Sciascia, Q. L.; Görs, S.; Vernunft, A.; Reyer, H.; Wimmers, K.; Zentek, J.; Kluess, J.; Dänicke, S.; Metges, C. C. (2025):
Measurement of Oro-Cecal Transit Time in LPS-Treated Pigs Fed High and Low Fiber Diets Using the Lactose-13C-Ureide Test in Breath and Saliva Samples
Journal of Agricultural and Food Chemistry 73 (17): 10304−10315
https://doi.org/10.1021/acs.jafc.5c00534
Reyer, H.; Mielenz, M.; Daş, G.; Metges, C. C.; Wimmers, K. (2025):
Microbial profiling of black soldier fly larvae reared on substrates supplemented with different mineral sources originating from phosphorus recycling technologies
Animal Microbiome 7: 14, 1-14
https://doi.org/10.1186/s42523-025-00380-5
Ponsuksili, S.; Hadlich, F.; Li, S.; Trakooljul, N.; Reyer, H.; Oster, M.; Abitew, Y. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):
DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages
Physiological Genomics 57 (3): 125-139
https://doi.org/10.1152/physiolgenomics.00063.2024