Prof. Dr. rer. nat. habil. Klaus Wimmers

Research Institute for Farm Animal Biology (FBN)
Director
Head of Working Group Physiological Genomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

ResearchGate

Research interests

inheritance and expression of traits related to productive adaptability and resilience in livestock
Trait-associated variation at the molecular levels of the genotype-phenotype map
Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

since 2016: director of the Research Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
2008-2016: adjunct Professor, University of Bonn
2004-2016: head of Institute for Genome Biology of the Research Institute for Farm Animal Biology (FBN)
2002: habilitation in Animal Breeding and Genetics, University of Bonn
1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
1994: doctorate (Dr. rer. nat.)
1990-1996: research fellow at the Institute of Animal production, TU Berlin
1989: Study of veterinary science, FU Berlin

Teaching

Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Reyer, H.; Mielenz, M.; Daş, G.; Metges, C. C.; Wimmers, K. (2025):

Microbial profiling of black soldier fly larvae reared on substrates supplemented with different mineral sources originating from phosphorus recycling technologies

Henry Reyer, Manfred Mielenz, Gürbüz Daş, Cornelia Christiane Metges, Klaus Wimmers

Animal Microbiome 7: 14, 1-14

https://doi.org/10.1186/s42523-025-00380-5

Ponsuksili, S.; Hadlich, F.; Li, S.; Trakooljul, N.; Reyer, H.; Oster, M.; Abitew, Y. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2025):

DNA methylation dynamics in the small intestine of egg-selected laying hens along egg production stages

Siriluck Wimmers, Shuaichen Li, Henry Reyer, Michael Oster, Yosef Amsalu Abitew, Klaus Wimmers

Physiological Genomics 57 (3): 125-139

https://doi.org/10.1152/physiolgenomics.00063.2024

Muráni, E.; Trakooljul, N.; Hadlich, F.; Wimmers, K. (2025):

Transcriptional signature of a hypersensitive glucocorticoid receptor variant in the neuroendocrine system suggests enhanced vulnerability to brain disorders

Eduard Muráni, Klaus Wimmers

Brain, Behavior and Immunity 124 (2): 335-346

https://doi.org/10.1016/j.bbi.2024.12.004

Ma, W.; Brenmoehl, J.; Trakooljul, N.; Wimmers, K.; Muráni, E. (2025):

Dexamethasone has profound influence on the energy metabolism of porcine blood leukocytes and prevents the LPS-induced glycolytic switch

Wenjuan Ma, Julia Brenmoehl, Klaus Wimmers, Eduard Muráni

Frontiers in Immunology 16: 1514061, 1-13

https://doi.org/10.3389/fimmu.2025.1514061

Sommerfeld, V.; Hanauska, A.; Huber, K.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):

Effects of myo-inositol supplementation in the diet on myo-inositol concentrations in the intestine, blood, eggs, and excreta of laying hens

Michael Oster, Klaus Wimmers, Siriluck Wimmers

Poultry Science: 104545, 1-30

https://doi.org/10.1016/j.psj.2024.104545

Sommerfeld, V.; Bennewitz, J.; Camarinha-Silva, A.; Feger, M.; Föller, M.; Huber, H.; Oster, M.; Ponsuksili, S.; Schmucker, S.; Seifert, J.; Stefanski, V.; Wimmers, K.; Rodehutscord, M. (2024):

Effects of feeding diets without mineral P supplement on intestinal phytate degradation, blood concentrations of Ca and P, and excretion of Ca and P in two laying hen strains before and after onset of laying activity

Michael Oster, Klaus Wimmers, Siriluck Wimmers

Poultry Science 103 (12): 104407, 1-12

https://doi.org/10.1016/j.psj.2024.104407

Omotoso, A. O.; Reyer, H.; Oster, M.; Ponsuksili, S.; Metzler-Zebeli, B.; Wimmers, K. (2024):

Hepatic Transcriptomics of Broilers with Low and High Feed Conversion in Response to Caloric Restriction

Henry Reyer, Michael Oster, Klaus Wimmers, Siriluck Wimmers

Metabolites 14: 625, 1-13

https://doi.org/10.3390/metabo14110625

Honerlagen, H.; Reyer, H.; Wimmers, K. (2024):

Fundamental insights into the host genome - rumen microbiota - trait complex of cow-individual nitrogen (N) utilisation and N excretion

Henry Reyer, Klaus Wimmers

Züchtungskunde 96 (1), 34-42

Abitew, Y. A.; Reyer, H.; Hadlich, F.; Oster, M.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2024):

Transcriptional responses to diets without mineral phosphorus supplementation in the jejunum of two high-yielding laying hen strains

Yosef Amsalu Abitew, Henry Reyer, Michael Oster, Klaus Wimmers, Siriluck Wimmers

Poultry Science 103 (12): 104484, 1-11

https://doi.org/10.1016/j.psj.2024.104484

Reyer, H.; Honerlagen, H.; Oster, M.; Ponsuksili, S.; Kuhla, B.; Wimmers, K. (2024):

Multi-tissue gene expression profiling of cows with a genetic predisposition for low and high milk urea levels

Henry Reyer, Michael Oster, Siriluck Wimmers, Björn Kuhla, Klaus Wimmers

Animal Biotechnology 35 (1): 2322542, 1-9

https://doi.org/10.1080/10495398.2024.2322542

Kalbfleisch, T. S.; McKay, S. D.; Murdoch, B. M.; Adelson, D. L.; Almansa-Villa, D.; Becker, G.; Beckett, L. M.; Benítez-Galeano, M. J.; Biase, F.; Casey, T.; Chuong, E.; Clark, E.; Clark, S.; Cockett, N.; Couldrey, C.; Davis, B. W.; Elsik, C. G.; Faraut, T.; Gao, Y.; Genet, C.; Grady, P.; Green, J.; Green, R.; Guan, D.; Hagen, D.; Hartley, G. A.; Heaton, M.; Hoyt, S. J.; Huang, W.; Jarvis, E.; Kalleberg, J.; Khatib, H.; Koepfi, K.-P.; Koltes, J.; Koren, S.; Kuehn, C.; Leeb, T.; Leonard, A.; Liu, G. E.; Low, W. Y.; McConnell, H.; McRae, K.; Miga, K.; Mousel, M.; Neibergs, H.; Olagunju, T.; Pennell, M.; Petry, B.; Pewsner, M.; Phillippy, A. M.; Pickett, B. D.; Pineda, P.; Potapova, T.; Rachagani, S.; Rhie, A.; Rijnkels, M.; Robic, A.; Osorio, N. R.; Safonova, Y.; Schettini, G.; Schnabel, R. D.; Natesh, N. S.; Stegemiller, N. R.; Storer, J.; Stothard, P.; Stull, C.; Tosser-Klopp, G.; Traglia, G. M.; Tuggle, C. K.; Tassell, C. P. Van; Watson, C.; Weikard, R.; Wimmers, K.; Xie, S.; Yang, L.; Smith, T. P. L.; O’Neil, R. J.; Rosen, B. D. (2024):

The Ruminant Telomere-to-Telomere (RT2T) Consortium

Klaus Wimmers

Nature genetics 56: 1566-1573

https://www.nature.com/articles/s41588-024-01835-2

Ponsuksili, S.; Siengdee, P.; Li, S.; Kriangwanich, W.; Oster, M.; Reyer, H.; Wimmers, K. (2024):

Effect of metabolically divergent pig breeds and tissues on mesenchymal stem cell expression patterns during adipogenesis

Siriluck Wimmers, Shuaichen Li, Michael Oster, Henry Reyer, Klaus Wimmers

BMC Genomics 25: 407, 1-15

https://doi.org/10.1186/s12864-024-10308-z

Li, S.; Siengdee, P.; Hadlich, F.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K.; Ponsuksili, S. (2024):

Dynamics of DNA methylation during osteogenic differentiation of porcinesynovial membrane mesenchymal stem cells from two metabolically distinctbreeds

Shuaichen Li, Michael Oster, Henry Reyer, Klaus Wimmers, Siriluck Wimmers

Epigenetics 19 (1): 2375011, 1-15

https://doi.org/10.1080/15592294.2024.2375011

Koch, F.; Reyer, H.; Görs, S.; Hansen, C.; Wimmers, K; Kuhla, B. (2024):

Heat stress and feeding effects on the mucosa-associated and digesta microbiome and their relationship to plasma and digesta fluid metabolites in the jejunum of dairy cows

Franziska Koch, Henry Reyer, Solvig Görs, Klaus Wimmers, Björn Kuhla

Journal of Dairy Science 107: 5162-5177

https://doi.org/10.3168/jds.2023-24242

Hasan, M.; Reyer, H.; Oster, M.; Trakooljul, N.; Ponsuksili, S.; Magowan, E.; Fischer, D.-C.; Wimmers, K. (2024):

Exposure to artificial ultraviolet-B light mediates alterations on the hepatic transcriptome and vitamin D metabolism in pigs

Henry Reyer, Michael Oster, Siriluck Wimmers, Klaus Wimmers

J Steroid Biochem Mol Biol 236: 106428, 1-8

https://doi.org/10.1016/j.jsbmb.2023.106428

Reyer, H.; Abou-Soliman, I.; Schulze, M.; Henne, H.; Reinsch, N.; Schön, J.; Wimmers, K. (2024):

Genome-Wide Association Analysis of Semen Characteristics in Piétrain Boars

Henry Reyer, Norbert Reinsch, Klaus Wimmers

Genes 15 (3): 382, 1-12

https://doi.org/10.3390/genes15030382

Nossol, C.; Landgraf, P.; Oster, M.; Kahlert, S.; Barta-Böszörmenyi, A.; Kluess, J.; Wimmers, K.; Isermann, B.; Stork, O.; Dieterich, D. C.; Dänicke, S.; Rothkötter, H. J. (2024):

Deoxynivalenol triggers the expression of IL-8-related signaling cascades and decreases protein biosynthesis in primary monocyte-derived cells

Michael Oster, Klaus Wimmers

Mycotoxin research 40 (2): 279-293

https://doi.org/10.1007/s12550-024-00528-3

Omotoso, A. O.; Reyer, H.; Oster, M.; Maak, S.; Ponsuksili, S.; Wimmers, K. (2023):

Broiler physiological response to low phosphorus diets at different stages of production. Poultry Sci 102 (2): 102351, 1-38

Henry Reyer, Michael Oster, Steffen Maak, Siriluck Wimmers, Klaus Wimmers

Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2023):

The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains. Poultry Sci 102 (1): 102256, 1-14

Siriluck Wimmers, Henry Reyer, Michael Oster, Muhammad Arsalan Iqbal, Klaus Wimmers

Salilew-Wondim, D.; Tholen, E.; Held-Hoelker, E.; Shellander, K.; Blaschka, C.; Drillich, M.; Iwersen, M.; Suess, D.; Gebremedhn, S.; Tesfaye, D.; Parys, C.; Helmbrecht, A.; Guyader, J.; Miskel, D.; Trakooljul, N.; Wimmers, K.; Hoelker, M. (2023):

Endometrial DNA methylation signatures during the time of breeding in relation to the pregnancy outcome in postpartum dairy cows fed a control diet or supplemented with rumen-protected methionine

Klaus Wimmers

Frontiers in Genetics 14: 1267053, 1-22

https://doi.org/10.3389/fgene.2023.1267053