Prof. Dr. rer. nat. Klaus Wimmers

+49 38208 68-602
Research Institute for Farm Animal Biology (FBN)
Director
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Germany

Research interests

  • inheritance and expression of traits related to productive adaptability and resilience in livestock
  • Trait-associated variation at the molecular levels of the genotype-phenotype map
  • Transcriptional response to exogenous stimuli and epigenetic basis of genotype-environment interaction

Curriculum Vitae

  • since 2016: director of the Leibniz-Institute for Farm Animal Biology & Professor "Animal Breeding and Genetics", Faculty of Agricultural and Environmental Science, University Rostock
  • 2008-2016: adjunct Professor, University of Bonn
  • 2004-2016: head of Institute for Genome Biology of the Leibniz-Institute for Farm Animal Biology (FBN)
  • 2002: habilitation in Animal Breeding and Genetics, University of Bonn
    1996-2003: scientific coworker at the Institute of Animal science, University of Bonn
  • 1994: doctorate (Dr. rer. nat.)
  • 1990-1996: research fellow at the Institute of Animal production, TU Berlin
  • 1989: Study of veterinary science, FU Berlin

Teaching

  • Lectures and seminars at the Faculty of Agriculture, University of Bonn and at the Faculty of Agricultural and Environmental Sciences, University of Rostock

Publications

Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Prahl, M.; Müller, C. B. M.; Albrecht, D.; Koch, F.; Wimmers, K.; Kuhla, B. (2022):
Hepatic urea, creatinine and uric acid metabolism in dairy cows with divergent milk urea concentrations. Sci Rep-UK 12: 17593, 1-14
https://doi.org/10.1038/s41598-022-22536-y
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Ponsuksili, S.; Murani, E.; Hadlich, F.; Perdomo-Sabogal, A.; Trakooljul, N.; Oster, M.; Reyer, H.; Wimmers, K. (2022):
Genetic regulation and variation of expression of miRNA and mRNA transcripts in fetal muscle tissue in the context of sex, dam and variable fetal weight. BIOL SEX DIFFER 13: 24, 1-14
https://doi.org/10.1186/s13293-022-00433-3
Vernunft, A.; Gladbach, C.; Oster, M.; Bostedt, H.; Wimmers, K. (2022):
Neue Erkenntnisse zur Vitalität und Verlusten bei Saugferkeln bei freier Abferkelung. In: 26. Mitteldeutscher Schweineworkshop in Bernburg, "Schweineproduktion und Schweinegesundheit - Was uns heute bewegt?!" (Hochschule Anhalt, Fachbereich Landwirtschaft, Prof. Dr. Heiko Scholz, Hrsg.) Hochschule Anhalt, Dessau (978-3-96057-134-6): 33-35"
Ponsuksili, S.; Hadlich, F.; Perdomo-Sabogal, A.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2022):
The dynamics of molecular, immune and physiological features of the host and the gut microbiome, and their interactions before and after onset of laying in two hen trains [epublished ahead of print]. Poultry Sci
https://doi.org/10.1016/j.psj.2022.102256
Perdomo-Sabogal, A.; Trakooljul, N.; Hadlich, F.; Murani, E.; Wimmers, K.; Ponsuksili, S. (2022):
DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity. Sci Rep-UK 12: 16293, 1-13
https://doi.org/10.1038/s41598-022-20682-x
Sarais, F.; Perdomo-Sabogal, A.; Wimmers, K.; Ponsuksili, S. (2022):
tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research. NON-CODING RNA 8 (3): 37, 1-19
https://doi.org/10.3390/ncrna8030037
Iqbal, M. A.; Reyer, H.; Oster, M.; Hadlich, F.; Trakooljul, N.; Perdomo-Sabogal, A.; Schmucker, S.; Stefanski, V.; Roth, C.; Camarinha-Silva, A.; Huber, K.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2022):
Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens. Front Genet 13: 858232, 1-20
https://doi.org/10.3389/fgene.2022.858232
Adzigbli, L.; Sokolov, E. P.; Wimmers, K.; Sokolova, I. M.; Ponsuksili, S. (2022):
Efects of hypoxia and reoxygenation on mitochondrial functions and transcriptional profles of isolated brain and muscle porcine cells. Sci Rep-UK 12: 19881, 1-17
https://doi.org/10.1038/s41598-022-24386-0
Li, Z.; Hadlich, F.; Wimmers, K.; Murani, E. (2022):
Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs. Front Immunol 13: 1
https://doi.org/10.3389/fimmu.2022.976454
Gerlinger, Ch.; Oster, M.; Reyer, H.; Polley, C.; Vollmar, B.; Muráni, E.; Wimmers, K.; Wolf, P. (2021):
Effects of excessive or restricted phosphorus and calcium intake during early life on markers of bone architecture and composition in pigs. J Anim Physiol An N 105 (S. 2): 52-62
https://doi.org/10.1111/jpn.13286
Noce, A.; Qanbari, S.; Gonzalez-Prendes, R.; Brenmoehl, J.; Luigi-Sierra, M. G.; Theerkorn, M.; Fiege, M.-A.; Pilz, H.; Bota, A.; Vidu, L.; Horwath, C.; Haraszthy, L.; Penchev, P.; Ilieva, Y.; Peeva, T.; Lüpcke, W.; Krawczynski, R.; Wimmers, K.; Thiele, M.; Hoeflich, A. (2021):
Genetic Diversity of Bubalus bubalis in Germany and Global Relations of Its Genetic Background. Front Genet 11: 610353, 1-16
https://doi.org/10.3389/fgene.2020.610353
Müller, C. B. M.; Görs, S.; Derno, M.; Tuchscherer, A.; Wimmers, K.; Zeyner, A.; Kuhla, B. (2021):
Differences between Holstein dairy cows in renal clearance rate of urea affect milk urea concentration and the relationship between milk urea and urinary nitrogen excretion. Sci Total Environ 755 (Pt 2): 143198, 1-12
https://doi.org/10.1016/j.scitotenv.2020.143198
Zheng, Y.; Chen, C.; Chen, W.; Wang, X.; Wang, W.; Gao, B.; Wimmers, K.; Mao, J.; Song, C. (2021):
Two new SINE insertion polymorphisms in pig Vertnin (VRTN) gene revealed by comparative genomic alignment. J Integr Agr 19 (10): 2514-2522
https://doi.org/10.1016/s2095-3119(20)63255-5
Oster, M.; Reyer, H.; Gerlinger, Ch.; Trakooljul, N.; Siengdee, P.; Keiler, J.; Ponsuksili, S.; Wolf, P.; Wimmers, K. (2021):
mRNA Profiles of Porcine Parathyroid Glands Following Variable Phosphorus Supplies throughout Fetal and Postnatal Life. Biomedicines 9 (5): 454, 1-14
https://doi.org/10.3390/biomedicines9050454
Sowoidnich, K.; Oster, M.; Wimmers, K.; Maiwald, M.; Sumpf, B. (2021):
Shifted excitation Raman difference spectroscopy as enabling technique for the analysis of animal feedstuff. J Raman Spectrosc 52 (8): 1418-1427
https://doi.org/10.1002/jrs.6140
Walz, C.; Brenmoehl, J.; Trakooljul, N.; Noce, A.; Caffier, C.; Ohde, D.; Langhammer, M.; Wimmers, K.; Ponsuksili, S.; Hoeflich, A. (2021):
Control of Protein and Energy Metabolism in the Pituitary Gland in Response to Three-Week Running Training in Adult Male Mice . Cells-Basel 10 (4): 736, 1-20
https://doi.org/10.3390/cells10040736
Li, Z.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K.; Murani, E. (2021):
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. Virulence 12 (1): 1808-1824
https://doi.org/10.1080/21505594.2021.1948276
Oster, M.; Reyer, H.; Keiler, J.; Ball, E.; Mulvenna, C.; Ponsuksili, S.; Wimmers, K. (2021):
Comfrey (Symphytum spp.) as a feed supplement in pig nutrition contributes to regional resource cycles. Sci Total Environ 796: 148988, 1-11
https://doi.org/10.1016/j.scitotenv.2021.148988